San Antonio Holidays

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    Save up to €900 when you book a flight and hotel together*
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Where to stay in San Antonio

Find the best San Antonio areas and neighborhoods for the activities you enjoy most. Learn more about San Antonio
A historic town with terracotta-roofed buildings, a prominent bell tower, and a sign for 'Edificio Domingo Guevara Yanez'.

Cusco Historic Center

6 out of top 10 points of interest in this area

Cusco Historic Center is known for its popular shops, and with sights like Santa Catalina Convent and Coricancha, you won't get bored spending a day wandering around this part of Cusco.

A densely packed urban street with terracotta-tiled roofs, narrow sidewalks, and a mix of residential and commercial buildings.

San Blas

Take a walk through the heart of Cusco’s artisan district, one of the city’s most beguiling and lively areas.

A cityscape with red-tiled roofs, a prominent church, and distant mountains.

San Cristóbal

While visiting San Cristóbal, you might make a stop by sights like Museo de Arte Precolombino and Plaza Sán Cristobal.

A person with arms outstretched, overlooking terraced agricultural fields in a mountainous landscape.

Santa Monica

While Santa Monica may not have many sights to explore, venturing just a little farther will lead you to top things to see and do like Real Plaza Cusco and Ttio Market.

A person climbing a stone wall with a backpack.

Santiago

If you're spending some time in Santiago, Santiago Plaza and "El Molino I" Shopping Center are top sights worth seeing.

Top hotels in San Antonio

Kantu Hotel

Kantu Hotel

calle chaparro 121 Cusco Cuzco
Fully refundableReserve now, pay when you stay
€53
31 Oct - 1 Nov
9/10 Wonderful! (690 reviews)
"It was good and clean."

Reviewed on 29 Sept 2026

Kantu Hotel
Palacio del Inka, A Luxury Collection Hotel by Marriott

Palacio del Inka, A Luxury Collection Hotel by Marriott

Plazoleta Santo Domingo No 259 Cusco Cusco
Fully refundableReserve now, pay when you stay
€341
30 Oct - 31 Oct
9.6/10 Exceptional! (1,004 reviews)
"Arqualogical, very "Cusco", a palace. Restaurant was very expensive in wines to the point that in my country i find the same wine at a cost per bottle less than what you charge by cup. A cup of regular wine can not cost 75 soles."

Reviewed on 28 Sept 2026

Palacio del Inka, A Luxury Collection Hotel by Marriott
Wyndham Costa del Sol Cusco

Wyndham Costa del Sol Cusco

Santa Teresa N 344 Cusco Cusco
€162
31 Oct - 1 Nov
9.4/10 Exceptional! (1,251 reviews)
"1"

Reviewed on 29 Sept 2026

Wyndham Costa del Sol Cusco
See all 1,867 properties in San Antonio
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a San Antonio holiday package cost?
We make it simple to travel the world, with San Antonio packages starting from as little as . You'll have the flexibility to combine your preferred hotels, airlines and car rental. For the ultimate escape, why not add a few activities and tours to your travel itinerary?
How do I get a cheap travel package to San Antonio?
Crafting your own San Antonio holiday package with Expedia is one of the easiest ways to save. We offer more than 550 partner airlines and 1,000,000 hotel options spread across the globe. With such a fabulous range to pick from, you'll have no trouble pulling together your perfect getaway.
Where should I stay in San Antonio?
With fascinating attractions such as Regional Hospital of Cusco and National University of Saint Anthony the Abbot in Cuzco in this neighbourhood, see if you can find a hotel near either of them. Real Plaza Cusco is another sight that visitors flock to.
What are the top hotels in San Antonio?
If it's comfort and convenience you're seeking, you can't go past Apart Las Margaritas Hotel. Spend your nights relaxing here and your days roaming around San Antonio's best sights.
How far in advance should I book my San Antonio holiday?
While not all air carriers advertise tickets early, you can normally start comparing international fares on Expedia up to a year in advance. This is the time you'll bag some incredible deals. If you've left things to the last minute, you might get lucky. Low prices sometimes emerge a few weeks before departure.
What does an Expedia San Antonio travel package include?
With Expedia, you can choose a combination of car rentals, hotels and flights to build your perfect San Antonio package. Once you've made your booking, you can add on fun stuff like sightseeing tours and activities. Remember, the more you bundle, the bigger the savings!
What should I know before booking a San Antonio travel package?
Bundling your bookings into a San Antonio holiday package is the easiest way to organise your trip. Not only that, you'll save big just for combining your hotels, flights and car rentals. Once you've booked, why not add on an activity or a tour?
Can I choose my airline with a San Antonio Expedia holiday package?
You can, and with more than 550 airlines to select from throughout the world, you're not short on choice. Look through the available options and see which airline best fits your budget and needs.
If I'm not able to travel, can I cancel my San Antonio holiday package?
Plans can change unexpectedly, so yes, you can. You may be able to cancel or change your San Antonio holiday package at no cost within 24 hours of booking. For older bookings, you can still cancel and rebook, but your car rental company, hotel or airline may charge a fee. Looking for more information? Check out our Customer Service Portal. We're here to help make sure your trip goes off without a hitch.

Things to do

Cusco: Rainbow Mountain and Red Valley Day Trip with Meals

Cusco: Rainbow Mountain and Red Valley Day Trip with Meals

€20
per adult
96% of travellers recommend
Cusco: Rainbow Mountain and Red Valley Day Trip with Meals
Cusco: Half-Day City Tour with Sacsayhuaman and Q'enco

Cusco: Half-Day City Tour with Sacsayhuaman and Q'enco

€12
per adult
100% of travellers recommend
Cusco: Half-Day City Tour with Sacsayhuaman and Q'enco
Cusco:Chinchero,Moray & Salt Mines drop-off in Ollantaytambo

Cusco:Chinchero,Moray & Salt Mines drop-off in Ollantaytambo

€32
per adult
Cusco:Chinchero,Moray & Salt Mines drop-off in Ollantaytambo
See all activities in Cusco
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.