San Cosme y Damian Holidays

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Top Flight + Hotel Deals in San Cosme y Damian

Price found within the past 48 hours. Click for updated prices.
Hotel Delle Civette

Hotel Delle Civette

Nomentano
€385
per person
26 Sept - 29 Sept
found 1 day ago
Return flight included
Dublin (DUB) to Rome (FCO)
9.6/10 Exceptional! (316 reviews)
Paolo and Alvis were especially helpful at check in and check out. But every single person at the reception is fantastic, it’s 24 hours you hand in your key they take care of it until you’re back whenever you want to come. Housekeeping was great and the room was incredibly clean. The area is quiet: mostly student and residential and is a 10 min walk from the metro station Bologna which connects you to Roma Termini (central station) in case you want to do day trip away from Rome, the Colosseum and many more main attractions is on the same direct line. Lots of supermarkets and restaurants around, and good night time vibe. Recommend visiting the museum that is just down the street from the hotel. Breakfast was included and was simple and tasty, coffee drinks were amazing and the staff is so lovely in the morning. Overall, highly recommend this hotel!

Reviewed on 3 Aug 2026

Hotiday Roma Trevi

Hotiday Roma Trevi

Rome City Centre
€1,876
per person
19 Sept - 26 Sept
found 13 hours ago
Return flight included
Shannon (SNN) to Rome (FCO)
No reviews
Relais de la Poste

Relais de la Poste

Rome City Centre
€1,174
per person
25 Oct - 1 Nov
found 1 day ago
Return flight included
Dublin (DUB) to Rome (FCO)
9.2/10 Wonderful! (707 reviews)
Nice hotel close to places to see things to do A/C didn’t work well in our room But staff moved us to another right away Great service

Reviewed on 12 Aug 2026

Il Campo Marzio

Il Campo Marzio

Rome City Centre
€633
per person
26 Sept - 29 Sept
found 1 day ago
Return flight included
Dublin (DUB) to Rome (FCO)
8.8/10 Excellent! (186 reviews)
Radio Hotel

Radio Hotel

Manhattan
Save 100% on your flight
€1,004
per person
26 Oct - 2 Nov
found 2 hours ago
Return direct flight included
Dublin (DUB) to New York (JFK)
8.6/10 Excellent! (2,493 reviews)
I really enjoyed my stay would definitely recommend.

Reviewed on 13 Aug 2026

Top hotels in San Cosme y Damian

Sun Hotel

Sun Hotel

Encarnacion Itapúa
€56
14 Sept - 15 Sept
includes taxes & fees
9/10 Wonderful! (133 reviews)
"Muy bien ubicado"

Reviewed on 9 Aug 2026

Sun Hotel
Carnaval Hotel Casino

Carnaval Hotel Casino

Av. Irrazabal, 750 Encarnacion
€64
16 Aug - 17 Aug
includes taxes & fees
9.4/10 Exceptional! (204 reviews)
"Muuuuy recomendado. Buenos amenities y buenisisima ubicación. Desayuno completisimo."

Reviewed on 19 Jul 2026

Carnaval Hotel Casino
Alula Hotel Encarnacion

Alula Hotel Encarnacion

1848 Gral Aquino Encarnación Itapúa
€84
13 Sept - 14 Sept
includes taxes & fees
Alula Hotel Encarnacion
See all 37 properties in Itapúa Department
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular San Cosme y Damian attractions

Guarani Jesuit Ruins of San Cosme and San Damián

Find out about the history of San Cosme y Damian when you take a trip to Guarani Jesuit Ruins of San Cosme and San Damián. Take in the museums while you're in the area.
See properties

Buenaventura Suarez Planetarium

9.0/10 (2 reviews)
You can spend time exploring the galleries in Buenaventura Suarez Planetarium in San Cosme y Damian. Take in the museums while you're in the area.
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Frequently asked questions

How much does a San Cosme y Damian holiday package cost?
You can pick up a holiday package to this popular destination from €385 on Expedia. But how much your holiday to San Cosme y Damian costs will depend on your hotel choice, length of stay and season.
What are the cheapest months to go to San Cosme y Damian?
If you're looking to book a cheap San Cosme y Damian holiday package, consider planning a trip in January, February and April. You'll typically find lower prices on hotels and flights during these months — perfect for travellers wishing to save money.
How many days is enough for San Cosme y Damian?
Generally, a handful of days is enough to check out the top attractions during your San Cosme y Damian holiday. But if you want to have time to relax or go on day tours, consider extending your trip.
How to find the best San Cosme y Damian package deals?
Use Expedia's filters to help you find some of the best San Cosme y Damian package deals. When you begin your search, just set your maximum budget and then sort the results by "Price: low to high." If you're looking to save, plan your break for midweek, or search for San Cosme y Damian package deals in the off-season. Play around with your travel dates and you may land even better discounts. As a rule of thumb, it's usually best to book your holiday package as early as possible.
Is it cheaper to book a San Cosme y Damian holiday as a package?
Expedia holiday packages are designed to help you keep more money in your pocket. Bundle your car rental, flight and hotel into one great-value price and you could save hundreds of dollars. You'll usually land a better deal than booking each component separately. And you'll still get the flexibility to create a personalised San Cosme y Damian holiday by choosing your favourite type of stay, airline and car class.
When to book a holiday package to San Cosme y Damian?
Secure incredible bargains by reserving your flights in advance with Expedia. If spontaneity is more your thing, take advantage of our last-minute deals for a spur-of-the-moment San Cosme y Damian getaway.
How to plan a trip to San Cosme y Damian?
  1. Choose when to go: Check your diary and get your bags packed. Your favourite time of year and the activities on offer will also help you decide when to holiday in San Cosme y Damian.
  2. Calculate your budget: Ensure you have enough money to cover everything from transportation and dining out to flights and experiences. Your accommodation will likely be the biggest expense during your trip to San Cosme y Damian.
  3. Decide your trip length: Think about how much time you want to spend discovering San Cosme y Damian. Plan your itinerary so you can get to all the attractions and activities you're interested in at a leisurely pace.
  4. Bundle your bookings: With your travel dates in order, you can combine your flights, car rental, hotels and more into a tailored San Cosme y Damian holiday package.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.