San Diego Hotel Guide - Business Hotels in San Diego, California

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Our top choices for San Diego business-friendly hotels

Room, 1 King Bed with Sofa bed, Marina View | View from room
Sheraton San Diego Resort

Sheraton San Diego Resort

Sheraton San Diego Resort
4.0 star property
Harbor Island
8.4 out of 10, Very good, (3167)
"Great stay! "
United States
Melissa
The price is €135
includes taxes & fees
28 Dec - 29 Dec
Sheraton San Diego Resort
Reception
Hampton Inn & Suites by Hilton San Diego SeaWorld

Hampton Inn & Suites by Hilton San Diego SeaWorld

Hampton Inn & Suites by Hilton San Diego SeaWorld
3.0 star property
Point Loma
9.2 out of 10, Wonderful, (423)
"Clean rooms, friendly staff."
United States
KARLA
The price is €99
includes taxes & fees
3 Jan - 4 Jan 2026
Hampton Inn & Suites by Hilton San Diego SeaWorld
3 restaurants, breakfast, lunch, dinner served; Regional cuisine
Wyndham San Diego Bayside

Wyndham San Diego Bayside

Wyndham San Diego Bayside
4.0 star property
Downtown San Diego
8.4 out of 10, Very good, (6040)
"Always an amazing stay"
United States
Jana
The price is €158
includes taxes & fees
22 Dec - 23 Dec
Wyndham San Diego Bayside
Standard Room, 1 King Bed, Non Smoking, Bay View
The DEXTRO Little Italy, BW Premier Collection

The DEXTRO Little Italy, BW Premier Collection

The DEXTRO Little Italy, BW Premier Collection
3.0 star property
Downtown San Diego
8.8 out of 10, Excellent, (760)
"Friendly staff and clean rooms. "
Canada
Justine
The price is €108
includes taxes & fees
21 Dec - 22 Dec
The DEXTRO Little Italy, BW Premier Collection
Exterior
Manchester Grand Hyatt San Diego

Manchester Grand Hyatt San Diego

Manchester Grand Hyatt San Diego
4.0 star property
Downtown San Diego
9.0 out of 10, Wonderful, (2874)
"Lovely hotel with friendly staff."
United States
Lynnea
The price is €196
includes taxes & fees
22 Dec - 23 Dec
Manchester Grand Hyatt San Diego
Outdoor pool, pool loungers
Hilton San Diego Bayfront

Hilton San Diego Bayfront

Hilton San Diego Bayfront
4.0 star property
Downtown San Diego
8.6 out of 10, Excellent, (1874)
"Enjoyed my stay"
United States
Brandon
The price is €158
includes taxes & fees
4 Jan - 5 Jan 2026
Hilton San Diego Bayfront
Exterior
San Diego Marriott Gaslamp Quarter

San Diego Marriott Gaslamp Quarter

San Diego Marriott Gaslamp Quarter
4.0 star property
Downtown San Diego
8.8 out of 10, Excellent, (1599)
"Clean room, comfortable beds. Good location and the staff was very friendly!!"
United States
Linda
The price is €125
includes taxes & fees
21 Dec - 22 Dec
San Diego Marriott Gaslamp Quarter
Exterior
Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG

Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG

Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG
2.5 star property
Otay Mesa
8.0 out of 10, Very good, (1566)
"Great place to stay. Really clean and helpful staff "
United States
Zulma
The price is €115
includes taxes & fees
21 Dec - 22 Dec
Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG
Standard Room, 2 Queen Beds, Non Smoking, Microwave
Best Western Yacht Harbor Hotel

Best Western Yacht Harbor Hotel

Best Western Yacht Harbor Hotel
2.5 star property
Point Loma
8.6 out of 10, Excellent, (1638)
"The breakfast options were good and the staff were very helpful."
Canada
Gail or Rob
The price is €98
includes taxes & fees
21 Dec - 22 Dec
Best Western Yacht Harbor Hotel
Terrace/patio
DoubleTree by Hilton San Diego - Del Mar

DoubleTree by Hilton San Diego - Del Mar

DoubleTree by Hilton San Diego - Del Mar
4.0 star property
Carmel Valley
8.4 out of 10, Very good, (1900)
"Excellent location"
United States
Paolo
The price is €95
includes taxes & fees
4 Jan - 5 Jan 2026
DoubleTree by Hilton San Diego - Del Mar
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top San Diego Hotel Reviews

The DEXTRO Little Italy, BW Premier Collection

The DEXTRO Little Italy, BW Premier Collection

10/10 Excellent
"Great"
Gabby 1-night trip
Posted 2 days ago
The DEXTRO Little Italy, BW Premier Collection

Frequently asked questions

How much do business-friendly hotels in San Diego cost?
You can expect to pay between €73 and €196 per night for business-friendly hotels in San Diego. Awesome deals on properties that are suitable for corporate travellers are just a few clicks away on Expedia. These prices were available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.
What are the best business-friendly hotels in San Diego?
A lot of corporate travellers recommend TownePlace Suites by Marriott San Diego Airport/Liberty Station. This 3-stars stay offers amenities such as a barbecue grill and a swimming pool. Tower23 Hotel is another top-rated option. It has a 4-stars rating and conveniences including an ocean view and a Tempur-Pedic mattress. You can pick from multiple business-friendly hotels in San Diego that have a total average guest review rating of 8.5.
How many business-friendly hotels are there in San Diego?
San Diego offers 248 hotels that accommodate corporate travellers. Whether you're searching for a central location or conveniences like dependable WiFi and conference rooms, you'll find the right property on Expedia.
What are the best cheap business-friendly hotels in San Diego?
TownePlace Suites by Marriott San Diego Airport/Liberty Station is a great choice for corporate travellers after a money-saving option. It comes with amenities like a swimming pool and a barbecue grill. Another economical stay for a work-related trip is  Hampton Inn & Suites San Diego Airport Liberty Station. An electric car charging station and a swimming pool are two of the conveniences here. Rates for business-friendly hotels in San Diego start at only €73 per night, so you'll have cash left over to spend on post-meeting activities. However, your San Diego visit shouldn't be all work and no play. Check out a few fun and free attractions, such as Mission Bay and Mission Beach. This price was available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.
What are the top business-friendly motels in San Diego?
Crown City Inn is a top pick, located about 3 kilometres southwest of downtown San Diego. Offering pool sun loungers and a garden, this business-friendly motel has what you need to get the job done. The Rambler Motel also caters to corporate travellers. It's around 10 kilometres southeast of central San Diego and includes a firepit, a swimming pool and more.There are so many things to do and see around San Diego. Take time out from your hectic schedule to visit leading attractions like San Diego Zoo and Mission Bay.
Are there any family-friendly hotels in San Diego that are also business friendly?
Pacific Terrace Hotel is a top pick for both leisure and corporate guests. A nearby theme park and a nearby beach are just two of the amenities you'll find at this 4-stars San Diego escape. Alternatively, get away with the family and get down to business at Homewood Suites by Hilton San Diego Airport/Liberty Station. Enjoy the use of conveniences such as complimentary breakfast and a playground at this leading 3-stars property. San Diego has plenty of family-friendly attractions to discover once you've wrapped up work. Make new memories with the kids at San Diego Zoo and Mission Bay.
Are there any 5-star business-friendly hotels in San Diego?
Book your spot at Pendry San Diego. Around 0.64 kilometres from the downtown area of San Diego, this business-friendly retreat has a 5-star rating and amenities including designer toiletries and room service. THE US GRANT, a Luxury Collection Hotel, San Diego is another 5-star pick that's ideal for corporate guests. It's situated about 0.16 kilometres from the city centre and offers designer toiletries and concierge services.
Why book your business-friendly hotel in San Diego with Expedia?
Expedia is here to help you find an ideal business-friendly hotel when you need to travel for work. From conference spaces and meeting rooms to on-site cafés and more, our stays have the things you need to get the job done.
How can I find cheap business-friendly hotels in San Diego?
When work takes you on the road in San Diego, our "business friendly" filter will help you find the right hotel. From free WiFi to workspaces and meeting rooms, they have the amenities you need to get the job done. Another handy tip? Narrow your search by your preferred star rating and budget to see the cheapest accommodation.
What is there to do in San Diego near my business-friendly hotel?
Whatever you love to do, San Diego has loads to keep you occupied. San Diego Zoo, Mission Bay and Mission Beach are on most visitors' sightseeing plans. Don't go home without exploring Coronado Beach, Seaport Village and Old Town San Diego State Park either. With Expedia's business-friendly hotel deals, you can discover even more wonderful attractions like these with the cash you save.

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