San Domino Holidays

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    Save up to €185 when you book a flight and hotel together*
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    Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package
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    Plan, book, and manage your trip all in one place

Top hotels in San Domino

Eden

Eden

3 out of 5
Via Garibaldi 1 - Isolotto Di San Domino, Tremiti Islands, FG
The price is €137 per night from 31 Aug to 1 Sept
€137
31 Aug - 1 Sept
includes taxes & fees
8.2/10 Very Good! (219 reviews)
"Friendly staff, great location. Katia at Reception was amazing"

Reviewed on 2 Aug 2025

Eden
Hotel Kyrie Isole Tremiti

Hotel Kyrie Isole Tremiti

3 out of 5
Isole Tremiti, San Domino, Tremiti Islands, FG
8/10 Very Good! (127 reviews)
"The hotel is in a very good location, walking distance (10-15mins) from the main square with shops, restaurants and a grocery shop. The hotel is in a beautiful scenery, up on the top of the island, with complimentary (free for guests of the hotel) frequent and very convenient shuttle transport from ..."

Reviewed on 13 Jul 2024

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Hotel Kyrie Isole Tremiti
L'ISOLA DEI SAPORI BOUTIQUE HOTEL

L'ISOLA DEI SAPORI BOUTIQUE HOTEL

STRADA PROVINCIALE 41 KM 34,00, Cagnano Varano, FG
9.2/10 Wonderful! (14 reviews)
"The owner was so kind and friendly."

Reviewed on 26 Jul 2025

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L'ISOLA DEI SAPORI BOUTIQUE HOTEL
See all 25 properties in San Domino
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Popular places to visit

San Domino Lighthouse

Learn about the local history of Tremiti Islands when you take a trip to San Domino Lighthouse. Wander the beaches and waterfront while you're in the area.

San Domino Lighthouse

Cala delle Arene Beach

Why not spend a care-free afternoon at Cala delle Arene Beach during your travels in Tremiti Islands? Wander the waterfront and parks while you're in the area.

Cala delle Arene Beach

Cala Matano

If a restful holiday is part of your travel plans, Cala Matano might be the perfect place to visit during your trip to Tremiti Islands. Wander the waterfront and parks while you're in the area.

Cala Matano

Frequently asked questions

How much does a San Domino holiday package cost?
Browse and book everything in one place with our San Domino holiday packages, which start from just . Handpick the hotels and flights that suit your plans. Then, add on a couple of sightseeing activities to cap off your unique adventure.
How do I get a cheap travel package to San Domino?
Booking a flight and hotel together with Expedia won't just save you time — it'll save you a few dollars too. A San Domino holiday package makes it a cinch to organise the perfect trip. With more than 550 airlines throughout the world to select from, finding flights that fit your busy schedule won't be a hassle. On top of that, we have over 1,000,000 hotel options globally to select from. Now that's choice! Whatever your budget, Expedia will help show you the world.
How far in advance should I book my San Domino holiday?
While prices change from time to time, we generally advise booking your seats as early as possible. Most international fares are available on Expedia up to a year in advance. If circumstances have left you booking last minute, you may still get lucky. Low prices to San Domino sometimes occur just weeks before departure.
What does an Expedia San Domino travel package include?
It comes down to what you want. If you're travelling by yourself, you might decide to bundle hotels and flights. Bringing the entire family to San Domino? A travel package including flights, hotels and rental cars might be a better fit. Expedia gives you the flexibility to tailor-make your travel package.
What should I know before booking a San Domino travel package?
You'll score terrific savings when you combine your hotels, flights and rental cars into a travel package. Plus, booking everything together just makes things easier. So why waste time or money? Whether you're putting together a luxury city stay with your love or a budget family adventure, browse our package deals today.
Can I choose my airline with a San Domino Expedia holiday package?
Yes, of course. We have more than 550 airline partners worldwide, so opt for the carrier that matches your budget needs.
If I'm not able to travel, can I cancel my San Domino holiday package?
Don't worry if you're rethinking your San Domino holiday package — it's possible to change or amend your booking. And if you've booked it within 24 hours, you may be able to do it at no cost. However, bookings made more than 24 hours ago may incur a fee from your airline, hotel or car rental company. We understand life can throw the occasional spanner in the works, so look up our Customer Service Portal if that happens. When you're ready to make changes, we'll take care of it.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.