San Fransisco District Holidays

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    Better together

    Save up to €185 when you book a flight and hotel together*
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    Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package
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    Rest easy

    Plan, book, and manage your trip all in one place

Top Flight + Hotel Deals in San Fransisco District

Price found within the past 48 hours. Click for updated prices.
MARINN Tropical Vibes Hotel

MARINN Tropical Vibes Hotel

3.5 out of 5
Amador
per person
14 Sept - 21 Sept
found 1 day ago
Return direct flight included
Dublin (DUB) to Panama City (PTY)
8/10 Very Good! (107 reviews)
The property is okay overall,the surroundings the only issue is that the property doesn't have a pool.

Reviewed on 25 Jun 2025

Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

4 out of 5
Casco Viejo
Save 100% on your flight
per person
14 Sept - 21 Sept
found 1 day ago
Return direct flight included
Dublin (DUB) to Panama City (PTY)
9/10 Wonderful! (925 reviews)
Love the location and the restaurant inside the hotel was phenomenal.

Reviewed on 11 Jul 2025

Waldorf Astoria Panama

Waldorf Astoria Panama

5 out of 5
Bella Vista
per person
14 Sept - 21 Sept
found 1 day ago
Return direct flight included
Dublin (DUB) to Panama City (PTY)
9/10 Wonderful! (1,002 reviews)
The customer service was top tier and the concierge, Lil always made the best record!

Reviewed on 14 Jul 2025

Megapolis Hotel Panamá

Megapolis Hotel Panamá

4.5 out of 5
San Francisco
per person
14 Sept - 21 Sept
found 1 day ago
Return direct flight included
Dublin (DUB) to Panama City (PTY)
8.4/10 Very Good! (936 reviews)
Excellent service, clean environment n excellent buffet

Reviewed on 9 Jul 2025

Arcadia Condo Suites

Arcadia Condo Suites

2.5 out of 5
Costa del Este
per person
14 Sept - 21 Sept
found 1 day ago
Return direct flight included
Dublin (DUB) to Panama City (PTY)
9.2/10 Wonderful! (29 reviews)
I had to wait 2 days to solve my tv issue. Weekend or not i should have been taken care of promptly. Overall the experience is nice. Rooms were good.

Reviewed on 7 Jul 2025

Top hotels in San Fransisco District

Hotel Gran David

Hotel Gran David

3.5 out of 5
Vía Interamericana, Santiago, Veraguas
Fully refundableReserve now, pay when you stay
8.4/10 Very Good! (310 reviews)
"I did not like the stale smell in the room when I entered it and the smell was persistent."

Reviewed on 12 Jun 2025

Get rates
Hotel Gran David
Hotel Mykonos Panama

Hotel Mykonos Panama

3.5 out of 5
Panamerican Highway, in front of Ruben Cantu Airport, Nuevo Santiago, Veraguas
Fully refundableReserve now, pay when you stay
The price is €85 per night from 26 Jul to 27 Jul
€85
26 Jul - 27 Jul
includes taxes & fees
8.8/10 Excellent! (519 reviews)
Good hotel ran by a great staff!
"The staff was friendly and helpful. Pool is one of my favorites clean with a swim up bar. Good breakfast buffet. I was there for a graduation ceremony, a good facility for that as well."

Reviewed on 13 Jul 2025

Hotel Mykonos Panama
HOTEL VISTA LAGO

HOTEL VISTA LAGO

3 out of 5
Rincón Largo, La Pena, Santiago de Veraguas
Fully refundableReserve now, pay when you stay
The price is €72 per night from 16 Jul to 17 Jul
€72
16 Jul - 17 Jul
includes taxes & fees
9.2/10 Wonderful! (60 reviews)
"Very clean, food was 10/10"

Reviewed on 10 Jul 2025

HOTEL VISTA LAGO
See all 25 properties in San Fransisco District
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a San Fransisco District holiday package cost?
Our San Fransisco District packages, which begin from just €813, are an easy way to save precious money. All you have to do is choose your favourite hotels, flights and more to create your ideal escape.
How do I get a cheap travel package to San Fransisco District?
Book everything all in one place with our San Fransisco District holiday packages. You'll find bargains on hotels, flights, tours and more that'll keep your pocketbook happy and your adventurous spirit busy. And, with more than 550 partner airlines and 1,000,000 properties throughout the world to choose from, you'll have endless opportunities to mix and match however you please.
How far in advance should I book my San Fransisco District holiday?
It's difficult to pick the best time for airfares, but we generally say the earlier, the better. Most international flights on Expedia become available up to a year in advance. If you can't book ahead, don't stress. Bargain prices occasionally appear within a few weeks of departure dates.
What does an Expedia San Fransisco District travel package include?
Car rentals, hotels and flights --- we connect you to all the best deals. All you have to do is select your ideal combination. Once you've made your booking, you can add on the fun stuff like activities and tours. Our travel packages make it easy to customize an exciting San Fransisco District getaway.
What should I know before booking a San Fransisco District travel package?
A package can be easier on the bank balance than separately booking everything you need for your adventure. For example, combine your hotels, flights and rental cars and score impressive savings. No matter your holiday goals, there's sure to be a package that matches your budget.
Can I choose my airline with a San Fransisco District Expedia holiday package?
Yes --- that's the beauty of an Expedia package. You can pick and choose your flights, hotels and more. We have more than 550 airline partners throughout the world, so you have options galore when creating your San Fransisco District escape.
If I'm not able to travel, can I cancel my San Fransisco District holiday package?
If your holiday plans in San Fransisco District have changed, it's a relief to know that you can amend or cancel your booking. If your booking was made in the last 24 hours, you may be able to get a refund. If your booking is older than that, your airline, hotel or car rental company may impose a cancellation fee. To find out more, visit our Customer Service Portal.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.