Milan Hotel Guide - San Sebastiano hotels in Milan, Italy.

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Tonight
19 Dec - 20 Dec
Tomorrow
20 Dec - 21 Dec
This weekend
19 Dec - 21 Dec
Next weekend
26 Dec - 28 Dec

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Our top choices for San Sebastiano hotels

Front of property
Oriana Homèl Milano

Oriana Homèl Milano

Oriana Homèl Milano
Centro Storico, 0.1 km from San Sebastiano
10.0 out of 10, Exceptional, (39)
"Perfect stay!"
Australia
Martin
The price is €161
includes taxes & fees
24 Dec - 25 Dec
Oriana Homèl Milano
Superior Apartment, 3 Bedrooms, Balcony , Via Cannobio 12 | Balcony
Heart Milan Apartments Duomo Missori

Heart Milan Apartments Duomo Missori

Heart Milan Apartments Duomo Missori
Centro Storico, 0.2 km from San Sebastiano
10.0 out of 10, Exceptional, (11)
"Great property and stay! The property was super communicative and met us at the apartment to give us the keys! The apartment was large with plenty of space, an awesome balcony, and comfy beds. The location was perfect - close to the Duomo and transpiration options (metro and tram stops) "
United States
Alison
The price is €193
includes taxes & fees
22 Dec - 23 Dec
Heart Milan Apartments Duomo Missori
Premium bedding, down duvets, pillow-top beds, minibar
AF Duomo - Milano Luxury Suites

AF Duomo - Milano Luxury Suites

AF Duomo - Milano Luxury Suites
Centro Storico, 0.3 km from San Sebastiano
9.8 out of 10, Exceptional, (28)
"Amazing view!!"
United States
Laura
The price is €636
includes taxes & fees
26 Dec - 27 Dec
AF Duomo - Milano Luxury Suites
Front of property
Room Mate Collection Giulia, Milan

Room Mate Collection Giulia, Milan

Room Mate Collection Giulia, Milan
4.0 star property
Centro Storico, 0.4 km from San Sebastiano
9.6 out of 10, Exceptional, (1001)
"Excellent stay from start to finish ."
United States
Sergey
The price is €345
includes taxes & fees
24 Dec - 25 Dec
Room Mate Collection Giulia, Milan
Deluxe Room, 1 King Bed
Casa Brivio

Casa Brivio

Casa Brivio
Centro Storico, 0.4 km from San Sebastiano
9.6 out of 10, Exceptional, (34)
"Memorable stay."
United States
Nabeel
Casa Brivio
Down duvets, minibar, in-room safe, blackout curtains
Speronari Suites

Speronari Suites

Speronari Suites
Centro Storico, 0.2 km from San Sebastiano
9.4 out of 10, Exceptional, (204)
"Great location."
United States
Bruce
The price is €303
includes taxes & fees
21 Dec - 22 Dec
Speronari Suites
Exterior
Ostello Bello Milano Duomo

Ostello Bello Milano Duomo

Ostello Bello Milano Duomo
0.4 km from San Sebastiano
9.4 out of 10, Exceptional, (250)
"Everything was perfect. Awesome location. Friendly staff, would definitely stay again. "
United States
Youbi
The price is €104
includes taxes & fees
22 Dec - 23 Dec
Ostello Bello Milano Duomo
Exterior
Santa Marta Suites

Santa Marta Suites

Santa Marta Suites
4.0 star property
Centro Storico, 0.2 km from San Sebastiano
9.2 out of 10, Wonderful, (157)
"Super location!"
United States
Ivan
Santa Marta Suites
Exterior
Matilde Boutique Hotel, WorldHotels Elite

Matilde Boutique Hotel, WorldHotels Elite

Matilde Boutique Hotel, WorldHotels Elite
4.0 star property
Centro Storico, 0.2 km from San Sebastiano
9.2 out of 10, Wonderful, (143)
"Great room, nice staff and breakfast. Concierge team was wonderful "
United States
Karrie Ellen
The price is €715
includes taxes & fees
31 Dec - 1 Jan 2026
Matilde Boutique Hotel, WorldHotels Elite
Bar (on property)
Park Hyatt Milano

Park Hyatt Milano

Park Hyatt Milano
5.0 star property
Scala, 0.5 km from San Sebastiano
9.6 out of 10, Exceptional, (285)
"Great location"
United States
Lisa
The price is €1,286
includes taxes & fees
22 Dec - 23 Dec
Park Hyatt Milano
View from property
Santa Marta Suites

Santa Marta Suites

Santa Marta Suites
Centro Storico, 0.2 km from San Sebastiano
9.4 out of 10, Exceptional, (136)
"Amazing location, amazing staff! The hotel has 5 floors, each with a suite and a hotel style room. The top floor has a terrace with views of the city. We walked everywhere during our stay. The front desk staff was fantastic, as was the restaurant. Thank you so much for a great first trip to Milano!"
United States
Brittany
Santa Marta Suites
Rooftop terrace
The Square Milano Duomo - Preferred Hotels & Resorts

The Square Milano Duomo - Preferred Hotels & Resorts

The Square Milano Duomo - Preferred Hotels & Resorts
4.0 star property
Centro Storico, 0.3 km from San Sebastiano
9.2 out of 10, Wonderful, (1000)
"Very nice hotel, nice rooms, great friendly staff, very nice location."
United States
Reem
The price is €350
includes taxes & fees
20 Dec - 21 Dec
The Square Milano Duomo - Preferred Hotels & Resorts
Bar (on property)
Palazzo Touring Club Milan, A Radisson Collection Hotel

Palazzo Touring Club Milan, A Radisson Collection Hotel

Palazzo Touring Club Milan, A Radisson Collection Hotel
5.0 star property
Centro Storico, 0.4 km from San Sebastiano
9.4 out of 10, Exceptional, (190)
"Very clean hotel nice staff the room is big and the shower was excellent The breakfast is amazing overall very good hotel We will definitely be back!"
United States
Galit
The price is €407
includes taxes & fees
21 Dec - 22 Dec
Palazzo Touring Club Milan, A Radisson Collection Hotel
Deluxe Condo
notaMi - Cinque Vie Top Floor City Center

notaMi - Cinque Vie Top Floor City Center

notaMi - Cinque Vie Top Floor City Center
0.4 km from San Sebastiano
9.6 out of 10, Exceptional, (15)
"My husband and my 7 years old daughter love this property. Clean, with everything you need for comfortable stay. Metro 8 min walking, near Duomo and other great places in Milan. Would stay there again."
United States
svitlana
The price is €298
includes taxes & fees
4 Jan - 5 Jan 2026
notaMi - Cinque Vie Top Floor City Center
Interior entrance
Brera Apartments in City Center

Brera Apartments in City Center

Brera Apartments in City Center
Centro Storico, 0.2 km from San Sebastiano
9.2 out of 10, Wonderful, (29)
"We really enjoyed our stay. It was in a great location with so many restaurants and shopping nearby along with historical sites."
United States
Leann
The price is €211
includes taxes & fees
6 Jan - 7 Jan 2026
Brera Apartments in City Center
Rooftop terrace
Prestige Boutique Homes Aparthotel Piazza Duomo View

Prestige Boutique Homes Aparthotel Piazza Duomo View

Prestige Boutique Homes Aparthotel Piazza Duomo View
Centro Storico, 0.2 km from San Sebastiano
9.4 out of 10, Exceptional, (46)
"Wonderful stay! The room was perfect and the view of the duomo was beautiful! The staff was outstanding and welcoming. Highly recommend!"
United States
Robert
The price is €376
includes taxes & fees
20 Dec - 21 Dec
Prestige Boutique Homes Aparthotel Piazza Duomo View
2 restaurants, Italian cuisine
Palazzo Cordusio Gran Meliá – The Leading Hotels of the World

Palazzo Cordusio Gran Meliá – The Leading Hotels of the World

Palazzo Cordusio Gran Meliá – The Leading Hotels of the World
5.0 star property
Centro Storico, 0.4 km from San Sebastiano
9.4 out of 10, Exceptional, (43)
"The room was extremely nice and the staff was kind"
United States
Roman
The price is €827
includes taxes & fees
20 Dec - 21 Dec
Palazzo Cordusio Gran Meliá – The Leading Hotels of the World
Property entrance
Luxury Suite Milano Duomo

Luxury Suite Milano Duomo

Luxury Suite Milano Duomo
Centro Storico, 0.3 km from San Sebastiano
9.4 out of 10, Exceptional, (231)
"Beds were very comfortable, location was awesome "
United States
Nadia
The price is €258
includes taxes & fees
15 Jan - 16 Jan 2026
Luxury Suite Milano Duomo
Courtyard
Milan Retreats Duomo

Milan Retreats Duomo

Milan Retreats Duomo
Centro Storico, 0.3 km from San Sebastiano
9.2 out of 10, Wonderful, (690)
"Great place and great apartment. I’ll come again "
United States
Mohammed
The price is €121
includes taxes & fees
21 Dec - 22 Dec
Milan Retreats Duomo
Rooftop terrace
ODSweet Duomo Milano Hotel

ODSweet Duomo Milano Hotel

ODSweet Duomo Milano Hotel
4.0 star property
Centro Storico, 0.2 km from San Sebastiano
9.2 out of 10, Wonderful, (167)
"Great location with a nice rooftop. Great room and great staff. I recommend it. "
United States
VICTOR
The price is €385
includes taxes & fees
24 Dec - 25 Dec
ODSweet Duomo Milano Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top San Sebastiano Hotel Reviews

The Square Milano Duomo - Preferred Hotels & Resorts

The Square Milano Duomo - Preferred Hotels & Resorts

10/10 Excellent
"The room was spacious and spotless. Perfect location. "
Douglas 3-night trip
Posted 3 days ago
The Square Milano Duomo - Preferred Hotels & Resorts

Hotels near other San Sebastiano attractions

Biblioteca Ambrosiana

One of Europe’s first public libraries is home to Leonardo da Vinci’s Codex Atlanticus, which is housed alongside a huge book and art collection.
See properties

Via Torino

During your visit to Milan, you can browse for the perfect souvenirs at Via Torino. Make time to visit the area's stunning cathedral or simply enjoy its charming cafes.
See properties

Frequently asked questions

What's the area like around San Sebastiano?
San Sebastiano is located in a historic area of Milan known for its stunning cathedral and top museums. If you're looking for a convenient place to stay, take a look at the 1290 hotels and other accommodation options you'll find within a mile.
What's the best place to stay near San Sebastiano?
Adjacent to San Sebastiano, Hotel Dei Cavalieri Milano Duomo is one of the top choices for your stay based on our traveller data, and this hotel offers a restaurant and a bar. Other good options within a short distance include The Square Milano Duomo - Preferred Hotels & Resorts and Hotel Brunelleschi.
How many hotels will I be able to find close to San Sebastiano?
Expedia has 1290 hotels and other accommodation options within a mile from San Sebastiano.
If I need to cancel the hotel reservation for my stay near San Sebastiano, will I receive a refund?
Yes, the majority of hotel bookings are fully refundable provided that you cancel prior to the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of check in. If you booked a non-refundable reservation, it may still be possible to cancel it and be given a refund within 24 hours of your booking. Enter dates in and click on "Search", then use the filter option "fully refundable" to view the best options available near San Sebastiano.
What can I see and do near San Sebastiano?
Museo del Novecento, Castello Sforzesco and Pinacoteca di Brera feature captivating exhibits. Sights like Cathedral of Milan, Biblioteca Ambrosiana and Royal Palace of Milan are must-sees while exploring the area. You can check out the local talent at Teatro alla Scala, Teatro Dal Verme and Teatro Manzoni.
How can I get to San Sebastiano?
With so many choices for transport, seeing the area around San Sebastiano is easy. You can access metro transport at Duomo Station, Via Orefici P.za Cordusio Tram Stop and Cordusio M1 Tram Stop. If you're taking a train into town, Milan Cadorna Nord Station and Milan (XNC-Cadorna Train Station) are the closest stations to Milan Centre.