San Sisto Holidays

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Top hotels in San Sisto

Villa di Piazzano - Small Luxury Hotel of the World

Villa di Piazzano - Small Luxury Hotel of the World

5 out of 5
Localita Piazzano, C.P. 6, Cortona, AR
The price is €550 per night from 12 Aug to 13 Aug
€550
12 Aug - 13 Aug
includes taxes & fees
9.6/10 Exceptional! (218 reviews)
"AMAZING! Gorgeous! I would recommend to everyone!"

Reviewed on 29 Jul 2025

Villa di Piazzano - Small Luxury Hotel of the World
Hotel Sangallo Palace

Hotel Sangallo Palace

4 out of 5
Via L Masi 9, Perugia, PG
Fully refundableReserve now, pay when you stay
The price is €139 per night from 7 Aug to 8 Aug
€139
7 Aug - 8 Aug
includes taxes & fees
8.8/10 Excellent! (573 reviews)
"What a lovely hotel. Rooms really comfortable and balcony a surprise extra"

Reviewed on 2 Aug 2025

Hotel Sangallo Palace
Giotto Hotel & Spa

Giotto Hotel & Spa

4 out of 5
Via Fontebella 41, Assisi, PG
8.8/10 Excellent! (709 reviews)
"Amazing views!!! ❤️ I attached a picture with the view from my room."

Reviewed on 22 Jul 2025

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Giotto Hotel & Spa
See all 3,412 properties in San Sisto
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Popular places to visit

Perugina Chocolate Factory

Enjoy an outing to Perugina Chocolate Factory during your stay in San Sisto. Discover the area's jazz scene and cathedral.

Perugina Chocolate Factory

Santa Maria della Misericordia Hospital

If Santa Maria della Misericordia Hospital is what brings you to town, hopefully you'll have a chance to explore more of Perugia.

Santa Maria della Misericordia Hospital

Renato Curi Stadium

Catch an event at Renato Curi Stadium during your trip to Perugia. Discover the local chocolate shops and its jazz scene while you're in the area.

Renato Curi Stadium

What to do in San Sisto

Perugia: San Lorenzo Cathedral Audioguide Tour

Perugia: San Lorenzo Cathedral Audioguide Tour

€4
per adult
Perugia: San Lorenzo Cathedral Audioguide Tour
Perugia: Chapter Museum Entry Ticket

Capitularies Museum of Saint Lorenzo Entry Ticket

€8
per adult
Capitularies Museum of Saint Lorenzo Entry Ticket
Perugia: Entry Ticket and Guided Tour of Perugia Underground

Perugia: Entry Ticket and Guided Tour of Perugia Underground

€12
per adult
90% of travellers recommend
Perugia: Entry Ticket and Guided Tour of Perugia Underground
See all activities in San Sisto

Frequently asked questions

How much does a San Sisto holiday package cost?
You can snap up a holiday package to this destination on Expedia. However, how much your holiday to San Sisto costs will depend on factors like the season, hotel choice and length of stay.
What are the cheapest months to go to San Sisto?
You're likely to find lower prices and better availability in January, February and March. Browse our cheap San Sisto holiday packages and you could get some excellent off-season deals.
How many days is enough for San Sisto?
With a well-planned schedule, you can easily tick off the most popular San Sisto sights in a few days. But if you want to discover hidden gems or go on day trips, consider booking your San Sisto holiday for longer.
How to find the best San Sisto package deals?
Use Expedia's handy filters to help you find some great San Sisto package deals. When you start your search, simply set your maximum budget and then sort the results by "Price: low to high." If you want to save, plan your escape for midweek, or browse for San Sisto package deals in the off-season. Switch up your travel dates and you may score even better discounts. As a rule of thumb, it's typically best to book your holiday package as early as possible.
Is it cheaper to book a San Sisto holiday as a package?
Expedia holiday packages are designed to help you keep more money in your pocket. Bundle your hotel, flight and car rental into one great-value price and you could save hundreds of dollars. You'll usually get a better deal than booking each component separately. And you'll still get the flexibility to create a tailored San Sisto holiday by choosing your favourite type of stay, airline and car class.
When to book a holiday package to San Sisto?
If you're planning a spur-of-the-moment San Sisto getaway, browse our last-minute deals that can be booked up to one week before you take off. Prefer not to wait until the last minute? You can land incredible deals on your hotels and flights by booking well in advance.
How to plan a trip to San Sisto?

  1. Choose your travel dates: What you'd like to do in San Sisto and your favourite season can help you decide when to go.
  2. Set a budget: Factor in costs like flights, food and transportation when working out how much to save for your trip to San Sisto. Then, choose a property that suits your budget, whether that's an affordable option or a more luxurious retreat.
  3. Determine how many days away: Start by making a list of all the activities and attractions you want to get to in San Sisto. Then, estimate how long you'll need for each, along with any travel time.
  4. Bundle your bookings: With your travel dates in order, you can combine your car rental, hotels, flights and more into a customised San Sisto holiday package.

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.