San Sisto Holidays

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Top hotels in San Sisto

Villa di Piazzano - Small Luxury Hotel of the World

Villa di Piazzano - Small Luxury Hotel of the World

5 out of 5
Localita Piazzano, C.P. 6, Cortona, AR
Fully refundableReserve now, pay when you stay
The price is €558 per night from 21 Jul to 22 Jul
€558
21 Jul - 22 Jul
includes taxes & fees
9.6/10 Exceptional! (212 reviews)
"Would definitely come back! The Italian garden at the property is beautiful."

Reviewed on 9 Jul 2025

Villa di Piazzano - Small Luxury Hotel of the World
Giotto Hotel & Spa

Giotto Hotel & Spa

4 out of 5
Via Fontebella 41, Assisi, PG
Fully refundableReserve now, pay when you stay
8.8/10 Excellent! (703 reviews)
"Beautiful scenery and a welcoming staff.The hotel's central location makes it easy to visit the Basilica of St. Francis and other Assisi attractions. Wonderful views, particularly at sunrise and sunset, of the Umbrian valley and the expansive terrace. Good Breakfast: With so many options, the breakfast ..."

Reviewed on 2 Jul 2025

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Giotto Hotel & Spa
TH Assisi - Hotel Cenacolo

TH Assisi - Hotel Cenacolo

4 out of 5
Viale Patrono d'Italia 70, Santa Maria degli Angeli, Assisi, PG
Fully refundableReserve now, pay when you stay
The price is €94 per night from 7 Aug to 8 Aug
€94
7 Aug - 8 Aug
includes taxes & fees
9/10 Wonderful! (550 reviews)
Great Stay
"Very clean and nice hotel, excellent restaurant, rooms large for Europe. Quiet area close to Assisi, will return. Parking available too."

Reviewed on 5 Jul 2025

TH Assisi - Hotel Cenacolo
See all 3,406 properties in San Sisto
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Popular places to visit

Perugina Chocolate Factory

Enjoy an outing to Perugina Chocolate Factory during your stay in San Sisto. Discover the area's jazz scene and cathedral.

Perugina Chocolate Factory

Santa Maria della Misericordia Hospital

If Santa Maria della Misericordia Hospital is what brings you to town, hopefully you'll have a chance to explore more of Perugia.

Santa Maria della Misericordia Hospital

Renato Curi Stadium

Catch an event at Renato Curi Stadium during your trip to Perugia. Discover the local chocolate shops and its jazz scene while you're in the area.

Renato Curi Stadium

What to do in San Sisto

Truffle hunting or Olive harvest - seasonal

Truffle hunting or Olive harvest - seasonal

€89
per adult
Truffle hunting or Olive harvest - seasonal
Wine tasting

Wine tasting

€70
per adult
Wine tasting
Experiences in Umbria, Toscana and Marche

Experiences in Umbria, Toscana and Marche

€60
per adult
Experiences in Umbria, Toscana and Marche
See all activities in San Sisto

Frequently asked questions

How much does a San Sisto holiday package cost?
You can snap up a holiday package to this destination on Expedia. However, how much your holiday to San Sisto costs will depend on factors like the season, hotel choice and length of stay.
What are the cheapest months to go to San Sisto?
You're likely to find lower prices and better availability in January, February and March. Browse our cheap San Sisto holiday packages and you could get some excellent off-season deals.
How many days is enough for San Sisto?
With a well-planned schedule, you can easily tick off the most popular San Sisto sights in a few days. But if you want to discover hidden gems or go on day trips, consider booking your San Sisto holiday for longer.
How to find the best San Sisto package deals?
Use Expedia's handy filters to help you find some great San Sisto package deals. When you start your search, simply set your maximum budget and then sort the results by "Price: low to high." If you want to save, plan your escape for midweek, or browse for San Sisto package deals in the off-season. Switch up your travel dates and you may score even better discounts. As a rule of thumb, it's typically best to book your holiday package as early as possible.
Is it cheaper to book a San Sisto holiday as a package?
Expedia holiday packages are designed to help you keep more money in your pocket. Bundle your hotel, flight and car rental into one great-value price and you could save hundreds of dollars. You'll usually get a better deal than booking each component separately. And you'll still get the flexibility to create a tailored San Sisto holiday by choosing your favourite type of stay, airline and car class.
When to book a holiday package to San Sisto?
If you're planning a spur-of-the-moment San Sisto getaway, browse our last-minute deals that can be booked up to one week before you take off. Prefer not to wait until the last minute? You can land incredible deals on your hotels and flights by booking well in advance.
How to plan a trip to San Sisto?

  1. Choose your travel dates: What you'd like to do in San Sisto and your favourite season can help you decide when to go.
  2. Set a budget: Factor in costs like flights, food and transportation when working out how much to save for your trip to San Sisto. Then, choose a property that suits your budget, whether that's an affordable option or a more luxurious retreat.
  3. Determine how many days away: Start by making a list of all the activities and attractions you want to get to in San Sisto. Then, estimate how long you'll need for each, along with any travel time.
  4. Bundle your bookings: With your travel dates in order, you can combine your car rental, hotels, flights and more into a customised San Sisto holiday package.

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.