Sanibel Isles Holidays

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Where to stay in Sanibel Isles

Find the best Sanibel Isles areas and neighborhoods for the activities you enjoy most. Learn more about Sanibel Isles
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Mid Island

3 out of top 10 points of interest in this area

If you're spending some time in Mid Island, Periwinkle Way and Sanibel Island Southern Beach are top sights worth seeing.

Find hotels in Mid Island

Top hotels in Sanibel Isles

Margaritaville Beach Resort Fort Myers

Margaritaville Beach Resort Fort Myers

4 out of 5
251 Crescent Street Fort Myers Beach FL
The price is €509 per night from 5 Mar to 6 Mar
€509
5 Mar - 6 Mar
includes taxes & fees
9/10 Wonderful! (1,912 reviews)
Very clean and great staff

Reviewed on 1 Mar 2026

Margaritaville Beach Resort Fort Myers
Sanibel Island Beach Resort

Sanibel Island Beach Resort

3 out of 5
1231 Middle Gulf Dr Sanibel FL
Fully refundableReserve now, pay when you stay
The price is €454 per night from 4 Mar to 5 Mar
€454
4 Mar - 5 Mar
includes taxes & fees
9.2/10 Wonderful! (1,648 reviews)
Clean room, newly redone since the hurricane a few years back. A few steps to the beach. Enjoyed the tiki bar. Restaurant food was very good. Would have liked a few more options for breakfast. I would recommend this resort for all the above.

Reviewed on 1 Mar 2026

Sanibel Island Beach Resort
Baymont by Wyndham Fort Myers Central

Baymont by Wyndham Fort Myers Central

2.5 out of 5
4850 S Cleveland Ave Fort Myers FL
Fully refundableReserve now, pay when you stay
The price is €86 per night from 1 Apr to 2 Apr
€86
1 Apr - 2 Apr
includes taxes & fees
6.8/10 (1,012 reviews)
Clean room, daily cleaning, friendly staff good price.

Reviewed on 1 Mar 2026

Baymont by Wyndham Fort Myers Central
See all 15,560 properties in Sanibel Isles
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Sanibel Isles holiday package cost?
Discover the best of Sanibel Isles from as low as . We offer a great selection of rental cars, hotels and flights to suit your travel style. You can pick up even better deals when you add a few tours or experiences to your holiday package.
How do I get a cheap travel package to Sanibel Isles?
If you love landing a bargain, bundle your bookings into a Sanibel Isles holiday package. Whether you need hotels, flights, rental cars or activities, you can browse and book everything in one place. You'll have ample choice at your fingertips as well. Expedia has over 550 partner airlines and 1,000,000 hotels across the globe to select from. Fly with who you want, stay where you like and save your hard-earned money — now that's the ideal getaway!
Where should I stay in Sanibel Isles?
With interesting attractions like Sanibel Island Lighthouse and Sanibel and Captiva Island Visitors Centre in this neighbourhood, see if you can find a hotel near either of them. Sanibel Island Northern Beach is another sight in Sanibel Isles that people flock to.
What are the top hotels in Sanibel Isles?
When it comes to comfortable places to stay in Sanibel Isles, you can't beat Post Hurricane Update. Take a look at our offers and land a bargain.
How far in advance should I book my Sanibel Isles holiday?
Be rewarded with the biggest variety and the cheapest prices by booking your trip to Sanibel Isles nice and early. Air carriers typically sell flights around 12 months before departure, so secure your spot as soon as you can. That said, Expedia is committed to giving you the best deals around, so it's always a good time to book your dream holiday!
What does an Expedia Sanibel Isles travel package include?
It comes down to what sort of trip you're thinking about. Sanibel Isles travel deals can include flights, hotels and car rentals. You can mix and match to find the bundle that suits you. You can also add on activities and experiences after you've booked to score even bigger discounts.
What should I know before booking a Sanibel Isles travel package?
A travel package can be more affordable than individually booking everything you need for your escape. For example, bundle your hotels, flights and rental cars and save a tidy sum. Whatever your holiday goals are, you're bound to find a package that's right for you.
Can I choose my airline with a Sanibel Isles Expedia holiday package?
Yes, the choice is yours. Expedia has access to more than 550 partner airlines across the globe, so you can tailor your Sanibel Isles escape according to your needs and budget.
If I'm not able to travel, can I cancel my Sanibel Isles holiday package?
You can. We totally understand that life happens, so we're here to help if you need to make changes to your Sanibel Isles holiday package. It may be possible to cancel or change your itinerary for free if you've booked in the last 24 hours. Your airline, hotel or car rental company may impose a fee if your booking was made more than 24 hours ago. Visit our Customer Service Portal for more information. Also, be sure to check your itinerary for the finer details on change fees.

Popular places to visit

Sanibel Island Lighthouse which includes a beach, general coastal views and a sunset

Sanibel Island Lighthouse

You can find out about the history of Sanibel with a trip to Sanibel Island Lighthouse. Wander through the beautiful beaches and seaside in this family-friendly area.

Sanibel Island Lighthouse
Periwinkle Way featuring a garden

Periwinkle Way

The island’s spine is also its commercial hub. Drive or bike the road’s length to find attractions and discover many stores and restaurants.

Periwinkle Way

Things to do

Copacetic Day Sail

Copacetic Day Sail

€59
per adult
100% of travellers recommend
Copacetic Day Sail
Dolphin Wildlife Cruise Fort Myers Beach

Dolphin Wildlife Cruise Fort Myers Beach

€54
per adult
Dolphin Wildlife Cruise Fort Myers Beach
Ft Myers Beach: Tropical Beach Getaway 3 Hour TikiPub Cruise

Ft Myers Beach 3hr Tiki Pub Tropical Sandbar Getaway Cruise

€85
per adult
Ft Myers Beach 3hr Tiki Pub Tropical Sandbar Getaway Cruise
See all activities in Sanibel
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.