Santa Cruz Holidays

  • Plan, book, travel with confidence

  • Better together

    Save up to €185 when you book a flight and hotel together*

  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package

  • Rest easy

    Plan, book, and manage your trip all in one place

Where to stay in Santa Cruz

Find the best Santa Cruz areas and neighborhoods for the activities you enjoy most. Learn more about Santa Cruz
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Centro - A

2 out of top 10 points of interest in this area

If you're spending some time in Centro - A, Brasil Plaza and Parque das Águas are top sights worth seeing.

Find hotels in Centro - A

Top hotels in Santa Cruz

I rent the Daily, (24hs) or Season of a Master Suite with Hydromassage.

I rent the Daily, (24hs) or Season of a Master Suite with Hydromassage.

Rondonópolis Mato Grosso
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I rent the Daily, (24hs) or Season of a Master Suite with Hydromassage.
Rede Andrade Center Premium

Rede Andrade Center Premium

3 out of 5
Av. Amazonas, 472 Rondonopolis MG
Fully refundableReserve now, pay when you stay
8.6/10 Excellent! (93 reviews)
Tudo perfeito adorei

Reviewed on 9 Mar 2026

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Rede Andrade Center Premium
Rede Andrade Rondonopolis

Rede Andrade Rondonopolis

2.5 out of 5
Rua Fernando Correa da Costa 624 Rondonopolis Mato Grosso
Fully refundableReserve now, pay when you stay
9/10 Wonderful! (166 reviews)
Otima localização

Reviewed on 11 Mar 2026

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Rede Andrade Rondonopolis
See all 27 properties in Santa Cruz
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Santa Cruz holiday package cost?
Starting from only , a holiday package is your passport to inexpensive travel. Put together your Santa Cruz escape by selecting from our wide range of flights, hotels and rental cars.
How do I get a cheap travel package to Santa Cruz?
Book everything in one place with our Santa Cruz holiday packages. You'll discover bargains on flights, hotels and more that'll keep your wallet happy and your adventurous side busy. And, with more than 550 air carriers and 1,000,000 properties throughout the world to pick from, you'll have endless opportunities to mix and match however you please.
Where should I stay in Santa Cruz?
With so much to explore in Santa Cruz, it'd be convenient for you to lock in a hotel near its attractions. Rondon Plaza Shopping, Santa Cruz Cathedral and Horto Florestal Park are some good ones to put on your to-do list.
How far in advance should I book my Santa Cruz holiday?
To bag discount prices, book early. Airlines generally release tickets, along with some of the lowest fares, nearly 12 months prior to departure. Hotels, activities and car rental should also be booked well in advance to avoid disappointment. If you've decided on a last-minute getaway to Santa Cruz, there are always plenty of great deals to be had on Expedia. Book your escape today!
What does an Expedia Santa Cruz travel package include?
Expedia has everything you need to plan your Santa Cruz escape, but what goes into your package is totally up to you. Select from any combination of flights, rental cars and hotels. Chasing some tours or activities to fill in your time? Once you've made your booking, you can add them too. Whatever your style or budget, there's a holiday package to suit your needs.
What should I know before booking a Santa Cruz travel package?
Tailor deals that match your budget with an Expedia package. Flights, hotels, rental cars — we've got them all. You'll save big dollars just for bundling your bookings. Whether you're going on an adventure in the snow or sunning yourself on a warm beach, your dream getaway is just clicks away.
Can I choose my airline with a Santa Cruz Expedia holiday package?
You sure can. We offer more than 550 partner airlines all over the world, so fly with the carrier that fits your needs.
If I'm not able to travel, can I cancel my Santa Cruz holiday package?
Because we know life can throw you a few curveballs, the answer is yes. For further information, head to our Customer Service Portal. But generally speaking, if you've booked your Santa Cruz holiday package in the last 24 hours, you may be able to cancel or change it without penalty. Your airline, hotel or car rental company may charge a fee if you made your booking a while ago.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.