Santa Fe Hotels

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Check prices for these dates

Tonight
9 Dec - 10 Dec
Tomorrow
10 Dec - 11 Dec
This weekend
12 Dec - 14 Dec
Next weekend
19 Dec - 21 Dec

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Our top choices for Santa Fe hotels

Restaurant
Hotel Eleo at the University of Florida

Hotel Eleo at the University of Florida

3.0 star property
Gainesville
9.4 out of 10, Exceptional, (1281)
"Second time here and will be coming back. Love this place"
United States
Nate
The price is €123
includes taxes & fees
14 Dec - 15 Dec
Hotel Eleo at the University of Florida
Outdoor pool
Sleep Inn & Suites University/Shands

Sleep Inn & Suites University/Shands

2.5 star property
Gainesville
8.8 out of 10, Excellent, (1032)
"Nice stay, pleasant staff. Surrounding area not outstanding but hotel itself was excellent "
United States
chris
The price is €79
includes taxes & fees
30 Dec - 31 Dec
Sleep Inn & Suites University/Shands
Exterior
Holiday Inn Express & Suites Alachua - Gainesville Area by IHG

Holiday Inn Express & Suites Alachua - Gainesville Area by IHG

3.5 star property
Alachua
9.4 out of 10, Exceptional, (1006)
"Staff was great and the location is perfect ! "
United States
JAY
The price is €109
includes taxes & fees
21 Dec - 22 Dec
Holiday Inn Express & Suites Alachua - Gainesville Area by IHG
Bar (on property)
DoubleTree by Hilton Gainesville

DoubleTree by Hilton Gainesville

4.0 star property
Gainesville
7.8 out of 10, Good, (1005)
"We thought the hotel was very nice and reasonable price. We especially liked the quality and comfort of the Bed, pillows and linens."
United States
Shirley
The price is €78
includes taxes & fees
16 Dec - 17 Dec
DoubleTree by Hilton Gainesville
Exterior
Hyatt Place Gainesville Downtown

Hyatt Place Gainesville Downtown

3.0 star property
Downtown Gainesville
9.2 out of 10, Wonderful, (1104)
"Great location great staff great experience I have stayed at the hotel before multiple times an again."
United States
Charles
The price is €100
includes taxes & fees
16 Dec - 17 Dec
Hyatt Place Gainesville Downtown
Free daily continental breakfast
Quality Inn Alachua - Gainesville Area

Quality Inn Alachua - Gainesville Area

2.5 star property
Alachua
7.2 out of 10, Good, (1003)
"The hotel staff was excellent at check-in and check out. "
United States
Edward
The price is €72
includes taxes & fees
16 Dec - 17 Dec
Quality Inn Alachua - Gainesville Area
Free daily full breakfast
Holiday Inn Express Starke by IHG

Holiday Inn Express Starke by IHG

2.5 star property
Starke
9.6 out of 10, Exceptional, (393)
"Excellent staff, clean room, amenities."
United States
Maria
The price is €91
includes taxes & fees
22 Dec - 23 Dec
Holiday Inn Express Starke by IHG
Exterior
Hilton University of Florida Conference Center Gainesville

Hilton University of Florida Conference Center Gainesville

3.5 star property
Gainesville
8.4 out of 10, Very good, (1003)
"I will recommend my friends and family to come at this location anytime they are in gainesville "
United States
Recardo
The price is €102
includes taxes & fees
16 Dec - 17 Dec
Hilton University of Florida Conference Center Gainesville
Exterior
Country Inn & Suites by Radisson, Gainesville, FL

Country Inn & Suites by Radisson, Gainesville, FL

3.0 star property
Gainesville
9.2 out of 10, Wonderful, (1618)
"Staff were very friendly, the room was clean and quiet. Very happy with our stay!"
United States
Stacey
The price is €90
includes taxes & fees
29 Dec - 30 Dec
Country Inn & Suites by Radisson, Gainesville, FL
Property amenity
AC Hotel by Marriott Gainesville Downtown

AC Hotel by Marriott Gainesville Downtown

2.5 star property
College Park
9.0 out of 10, Wonderful, (461)
"First time staying here and loved the convenience, will stay here again:) "
United States
Ericka
The price is €125
includes taxes & fees
14 Dec - 15 Dec
AC Hotel by Marriott Gainesville Downtown
Exterior
Best Western Gateway Grand

Best Western Gateway Grand

3.0 star property
Gainesville
8.6 out of 10, Excellent, (1348)
"Staff was great. Clean and breakfast was fantastic!"
United States
Mary
The price is €90
includes taxes & fees
16 Dec - 17 Dec
Best Western Gateway Grand
Exterior
Extended Stay America Select Suites Gainesville I-75

Extended Stay America Select Suites Gainesville I-75

2.5 star property
Gainesville
6.0 out of 10, (1000)
"Great stay. "
United States
Thomas
The price is €65
includes taxes & fees
23 Dec - 24 Dec
Extended Stay America Select Suites Gainesville I-75
Breakfast area
Hampton Inn & Suites Alachua I-75

Hampton Inn & Suites Alachua I-75

2.5 star property
Alachua
9.4 out of 10, Exceptional, (472)
"Staff very helpful- clean updated facility. "
United States
bethany
The price is €92
includes taxes & fees
1 Jan - 2 Jan 2026
Hampton Inn & Suites Alachua I-75
Lobby
Red Roof Inn PLUS+ Gainesville

Red Roof Inn PLUS+ Gainesville

2.5 star property
Gainesville
7.4 out of 10, Good, (1231)
"Just drove through and needed a place to stay seems decent!"
United States
Jordan
The price is €64
includes taxes & fees
10 Dec - 11 Dec
Red Roof Inn PLUS+ Gainesville
Exterior
Hampton Inn & Suites Gainesville-Downtown

Hampton Inn & Suites Gainesville-Downtown

3.0 star property
Downtown Gainesville
8.6 out of 10, Excellent, (1003)
"clean room, nice locations"
United States
Christine
The price is €74
includes taxes & fees
19 Dec - 20 Dec
Hampton Inn & Suites Gainesville-Downtown
Property amenity
Hotel Indigo Gainesville-Celebration Pointe by IHG

Hotel Indigo Gainesville-Celebration Pointe by IHG

3.5 star property
Gainesville
9.0 out of 10, Wonderful, (1004)
"Super nice hotel. Comfortable and clean too. The food in their restaurant was delicious! "
United States
MACEY
The price is €99
includes taxes & fees
16 Dec - 17 Dec
Hotel Indigo Gainesville-Celebration Pointe by IHG
Outdoor pool
Best Western Waldo Inn and Suites

Best Western Waldo Inn and Suites

2.5 star property
Waldo
8.8 out of 10, Excellent, (950)
"Room was clean, staff was very friendly, loved the breakfast"
United States
Christina
The price is €99
includes taxes & fees
22 Dec - 23 Dec
Best Western Waldo Inn and Suites
Lobby
SpringHill Suites by Marriott Gainesville

SpringHill Suites by Marriott Gainesville

3.0 star property
Gainesville
8.8 out of 10, Excellent, (1000)
"The room is gorgeous,and the staff is friendly."
United States
Jimmy
The price is €90
includes taxes & fees
22 Dec - 23 Dec
SpringHill Suites by Marriott Gainesville
Deluxe Room, 2 Queen Beds, Non Smoking
HOM Hotel Gainesville, SureStay Collection by Best Western

HOM Hotel Gainesville, SureStay Collection by Best Western

2.5 star property
Gainesville
8.4 out of 10, Very good, (1798)
"Nice place to stay"
United States
Balasubramani
The price is €74
includes taxes & fees
16 Dec - 17 Dec
HOM Hotel Gainesville, SureStay Collection by Best Western
Lobby
Comfort Suites Gainesville near University

Comfort Suites Gainesville near University

2.5 star property
Gainesville
9.2 out of 10, Wonderful, (1144)
"Clean rooms, pet friendly, great staff & nice amenities. "
United States
Phillip
The price is €86
includes taxes & fees
23 Dec - 24 Dec
Comfort Suites Gainesville near University
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Santa Fe Hotel Reviews

Holiday Inn Express & Suites Alachua - Gainesville Area by IHG

Holiday Inn Express & Suites Alachua - Gainesville Area by IHG

10/10 Excellent
"We stayed here for Thanksgiving, and it was great. The room was clean, the staff was awesome, and breakfast was delicious. The location is conveniently close to the freeway, with Publix just across the parking lot, and there are multiple food options nearby. We will definitely stay here again."
Keri 2-night trip
Posted 2 days ago
Holiday Inn Express & Suites Alachua - Gainesville Area by IHG

More cheap stays in Santa Fe

Days Inn by Wyndham Gainesville University I-75

Days Inn by Wyndham Gainesville University I-75

920 Nw 69th Ter Gainesville FL
The price is €62 per night from 10 Dec to 11 Dec
€62
10 Dec - 11 Dec
includes taxes & fees
5.4/10 (1,003 reviews)

Frequently asked questions

What's the best place for a stay in Santa Fe?
Located 17.8 mi (28.7 km) from the heart of Santa Fe, Hotel Eleo at the University of Florida is a top choice for your stay, based on our traveller data. Other good choices for your stay in the area are HOM Hotel Gainesville, SureStay Collection by Best Western and Sleep Inn & Suites University/Shands. See all available top hotels, or vacation rentals in Santa Fe.
What are some of the best holiday rentals that Santa Fe has to offer?
Walking distance to Brewery and Restaurants ⭐️⭐️⭐️⭐️⭐️: This holiday home rental outside of Santa Fe is located on a river, and has a fireplace, a patio and air conditioning to put you at ease in your new surroundings. Kitchen amenities include a dishwasher, a fridge and a stovetop. Make the most of games in this rental home to help you unwind. See all vacation rentals in Santa Fe.
If I need to cancel my hotel reservation in Santa Fe, will I receive a refund?
Yes! Most hotel room reservations are fully refundable if cancelled before the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of the scheduled arrival. If you have a non-refundable reservation, you might be able to cancel it and get a refund within 24 hours of booking. Filter your search by fully refundable to find flexible hotel deals in Santa Fe.
What is staying in Santa Fe like?
Travellers to Santa Fe will find plenty to explore and enjoy. There are 709 hotels and other accommodation options in the surrounding area. Find out more about Santa Fe.
What is there to see in Santa Fe?
Places to visit in the wider area include O'Leno State Park, San Felasco Hammock Preserve State Park and Lakeside Park. You'll also find Devil's Milhopper Geological State Park and Gainesville Raceway in the area. Take a look at what more there is to see and do in Expedia's Santa Fe guide.
What's the weather like in Santa Fe?
The hottest months are usually July and August, with an average temperature of 27°C, while the coldest months are January and February, with an average of 15°C. The rainiest months in Santa Fe are August, June, July and September, with each month seeing an average of 177 mm of rainfall.

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