Santa Isabel Hotels

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16 Dec - 17 Dec
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17 Dec - 18 Dec
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19 Dec - 21 Dec
Next weekend
26 Dec - 28 Dec

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Our top choices for Santa Isabel hotels

Outdoor pool
Holiday Inn Express & Suites Mexicali by IHG

Holiday Inn Express & Suites Mexicali by IHG

Holiday Inn Express & Suites Mexicali by IHG
3.0 star property
Mexicali
9.4 out of 10, Exceptional, (1004)
Set near Plaza La Gran Via, this hotel offers a refreshing outdoor pool for morning swims and a fitness centre. Free breakfast, WiFi, and parking enhance the stay, while attentive staff ensure comfort during business or leisure visits to Mexicali.
"Wonderful, excellent stay!"
United States
Martha
The price is €71
includes taxes & fees
9 Jan - 10 Jan 2026
Holiday Inn Express & Suites Mexicali by IHG
Lobby
Fairfield Inn & Suites by Marriott Mexicali

Fairfield Inn & Suites by Marriott Mexicali

Fairfield Inn & Suites by Marriott Mexicali
2.5 star property
Mexicali
9.6 out of 10, Exceptional, (1005)
Located minutes from the Mexico-USA border, this hotel offers complimentary parking and daily buffet breakfast. Take a refreshing dip in the outdoor pool after exploring nearby Plaza Cataviña and Plaza La Gran Via attractions.
"Staff friendly really clean overall Great hotel!!! A plus great location "
United States
Daniel
The price is €97
includes taxes & fees
26 Dec - 27 Dec
Fairfield Inn & Suites by Marriott Mexicali
Lounge
Hotel Araiza Mexicali

Hotel Araiza Mexicali

Hotel Araiza Mexicali
4.0 star property
Mexicali
8.6 out of 10, Excellent, (1731)
Centrally positioned near restaurants and shops, this hotel offers 2 outdoor pools, a hot tub, and fitness centre. Guests enjoy free WiFi and parking while exploring nearby attractions like Eagles Nest Stadium and Arenia Casino.
"Great hotel "
United States
Beatriz
The price is €113
includes taxes & fees
1 Jan - 2 Jan 2026
Hotel Araiza Mexicali
Property amenity
Courtyard by Marriott Mexicali

Courtyard by Marriott Mexicali

Courtyard by Marriott Mexicali
3.0 star property
Mexicali
9.4 out of 10, Exceptional, (819)
Enjoy Mexicali's attractions with a stay at this modern hotel, featuring an international restaurant and bar, fitness centre, and terrace. Close to Plaza La Gran Via and the Mexico-USA border, the hotel offers clean rooms with free WiFi and parking.
"Great location, clean hotel rooms, friendly staff. "
United States
Elizabeth
The price is €100
includes taxes & fees
21 Dec - 22 Dec
Courtyard by Marriott Mexicali
Lobby
City Express Plus by Marriott Mexicali

City Express Plus by Marriott Mexicali

City Express Plus by Marriott Mexicali
3.5 star property
Mexicali
8.6 out of 10, Excellent, (1003)
This business-friendly hotel offers a refreshing outdoor pool and convenient on-site dining. Free breakfast, WiFi, and parking enhance your stay while the helpful staff ensures comfort. Explore nearby Arenia Casino and UABC Cultural Studies Institute from this clean, accessible location.
"Excellent hotel"
United States
Agustin
The price is €61
includes taxes & fees
21 Dec - 22 Dec
City Express Plus by Marriott Mexicali
Exterior
Hotel Lucerna Mexicali

Hotel Lucerna Mexicali

Hotel Lucerna Mexicali
4.0 star property
Mexicali
9.2 out of 10, Wonderful, (1434)
Discover a peaceful retreat at this Mexicali hotel with a refreshing outdoor pool and fitness centre. Just 15 minutes from the international border, guests love the quiet atmosphere, helpful staff, and proximity to Eagles Nest Stadium and Arenia Casino.
"excellent service, room really nice. hostess where really friendly. room service available delicious food."
United States
sandra
The price is €101
includes taxes & fees
30 Dec - 31 Dec
Hotel Lucerna Mexicali
Outdoor pool
Calafia Hotel

Calafia Hotel

Calafia Hotel
3.5 star property
Eguía
8.2 out of 10, Very good, (1007)
Experience tranquility at this Mexicali hotel, just 15 minutes from the Mexico-USA border. Take a refreshing dip in the outdoor pool, enjoy meals at Cafeteria Palmira, or unwind at the bar. Near Eagles Nest Stadium and Arenia Casino with attentive staff.
"The room was nice and clean. We stayed for a couple of nights and were very happy with our visit."
United States
Lauren
The price is €75
includes taxes & fees
21 Dec - 22 Dec
Calafia Hotel
Interior entrance
Sleep Inn Mexicali

Sleep Inn Mexicali

Sleep Inn Mexicali
3.0 star property
Mexicali
8.2 out of 10, Very good, (1004)
Stylish business-friendly hotel in Mexicali offers free breakfast, WiFi, and parking within 15 minutes of the International Border Line. Visit the fitness centre for a workout, and explore nearby Casino Caliente and Plaza La Gran Via. The helpful staff ensures a pleasant stay.
"Friendly staff, clean rooms "
United States
Sara
The price is €64
includes taxes & fees
19 Dec - 20 Dec
Sleep Inn Mexicali
Lobby
City Express Junior by Marriott Mexicali

City Express Junior by Marriott Mexicali

City Express Junior by Marriott Mexicali
3.0 star property
Mexicali
7.8 out of 10, Good, (1001)
Located just a 15-minute drive from the Mexico-USA border, this business-friendly hotel offers complimentary continental breakfast, WiFi, and self parking. Explore nearby Casino Caliente and Plaza La Gran Via attractions during your Mexicali visit.
"Excellent location and great price. Will definitely stay here again"
United States
Luis
The price is €52
includes taxes & fees
14 Jan - 15 Jan 2026
City Express Junior by Marriott Mexicali
Front of property – evening/night
Hotel del Norte

Hotel del Norte

Hotel del Norte
3.0 star property
Mexicali Historic Center
8.2 out of 10, Very good, (1006)
Enjoy Mexican cuisine at RESTAURANTE DEL NORTE after exploring nearby cultural sites. Free breakfast, WiFi, and parking enhance your stay at this Mexicali hotel. The helpful staff receives consistent praise from fellow travellers.
"Breakfast great. Convenient "
United States
Eddie
The price is €52
includes taxes & fees
22 Dec - 23 Dec
Hotel del Norte
Interior detail
Extended Suites Mexicali Cataviña

Extended Suites Mexicali Cataviña

Extended Suites Mexicali Cataviña
3.0 star property
Mexicali
8.0 out of 10, Very good, (2202)
Centrally located in Mexicali, this aparthotel offers apartment-style living with practical kitchenettes and LCD TVs. The outdoor pool provides refreshing relaxation while the 24-hour fitness centre and front desk ensure convenience at any hour. Plaza Cataviña and Plaza La Gran Via are just moments away.
"Very nice people clean rooms all new appliances excellent service and great location will recommend to anyone looking for good rest! "
United States
JOSE
Extended Suites Mexicali Cataviña
Double Room
Motel Diana

Motel Diana

Motel Diana
2.5 star property
Mexicali
9.2 out of 10, Wonderful, (7)
"Bed was hard "
United States
Luger
The price is €31
includes taxes & fees
18 Dec - 19 Dec
Motel Diana
Front of property
Motel Olimpo

Motel Olimpo

Motel Olimpo
2.0 star property
Mexicali
8.0 out of 10, Very good, (2)
"Nice and a clean place. "
United States
Sonia
The price is €35
includes taxes & fees
18 Dec - 19 Dec
Motel Olimpo
Lobby sitting area
Real Inn Mexicali

Real Inn Mexicali

Real Inn Mexicali
4.0 star property
Civic Center
8.2 out of 10, Very good, (1556)
Within a 15-minute drive of the Mexico-USA border, this business-friendly hotel features an outdoor pool and fitness centre. Grab international cuisine at Stock Cafe or unwind at the bar. Enjoy free WiFi, parking, and easy access to Sol Children's Museum and Vicente Guerrero Park.
"It was a good stay. "
United States
Miguel
The price is €80
includes taxes & fees
28 Dec - 29 Dec
Real Inn Mexicali
Lobby lounge
City Express by Marriott Mexicali

City Express by Marriott Mexicali

City Express by Marriott Mexicali
3.0 star property
Mexicali
8.2 out of 10, Very good, (1010)
Located within a 15-minute drive of Mexico-USA border, this hotel offers free WiFi and continental breakfast on weekdays. Visit the health club for a workout after exploring nearby Eagles Nest Stadium and Arenia Casino. Guests consistently praise the clean rooms and attentive staff.
"The are is safe and nice restaurants around. "
United States
Judy
The price is €79
includes taxes & fees
19 Dec - 20 Dec
City Express by Marriott Mexicali
Front of property
Hotel Cosmos Don Carlos

Hotel Cosmos Don Carlos

Hotel Cosmos Don Carlos
3.0 star property
Eguía
8.0 out of 10, Very good, (490)
Located near the International Border Line Mexico-USA, this hotel offers a convenient outdoor pool and Mexican cuisine at Fonda Don Carlos restaurant. With free WiFi and parking, it's just minutes from Eagles Nest Stadium and Arenia Casino.
"Great stay!"
United States
Gustavo Adolfo
Hotel Cosmos Don Carlos
Exterior
One Mexicali

One Mexicali

One Mexicali
3.0 star property
Mexicali
7.8 out of 10, Good, (1004)
Just 15 minutes from the International Border Line Mexico-USA, this business-friendly hotel offers a daily buffet breakfast and free WiFi. Visit nearby Arenia Casino or explore UABC Cultural Studies Institute, both within easy reach.
"NICE PLACE"
United States
ROBERTO
The price is €67
includes taxes & fees
20 Dec - 21 Dec
One Mexicali
Interior
Hotel Siesta Real

Hotel Siesta Real

Hotel Siesta Real
3.0 star property
Mexicali
8.2 out of 10, Very good, (896)
This comfortable hotel offers an outdoor pool and restaurant just a short drive from Arenia Casino and Eagles Nest Stadium. Enjoy free WiFi and parking during your stay, with easy access to local attractions.
"Easy check in , close to restaurants and shopping "
United States
Danny
The price is €73
includes taxes & fees
18 Dec - 19 Dec
Hotel Siesta Real
TV
Hotel Colonial Mexicali

Hotel Colonial Mexicali

Hotel Colonial Mexicali
3.5 star property
Civic Center
8.0 out of 10, Very good, (1012)
This Colonial hotel offers 2 refreshing outdoor pools and a children's pool, plus a restaurant and terrace. Located just 15 minutes from the Mexico-USA border, with convenient access to Sol Children's Museum and Vicente Guerrero Park.
"Great hotel"
United States
Juan
Hotel Colonial Mexicali
Exterior
Motel Marche

Motel Marche

Motel Marche
3.0 star property
Mexicali
8.2 out of 10, Very good, (153)
Unwind at this laid-back Mexicali motel offering 24-hour room service and a convenient bar/lounge. Located close to City Forest and Zoo and Sol Children's Museum, guests appreciate the attentive service and complimentary WiFi and parking.
"Very clean and property was very well kept."
United States
Angel
The price is €65
includes taxes & fees
18 Dec - 19 Dec
Motel Marche
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Santa Isabel Hotel Reviews

Hotel Lucerna Mexicali

Hotel Lucerna Mexicali

10/10 Excellent
"Very goog"
Melecio 1-night trip
Posted 2 days ago
Hotel Lucerna Mexicali

More cheap stays in Santa Isabel

Motel Diana

Motel Diana

200 Av. Tabasco Loma Linda Mexicali BC
The price is €31 per night from 18 Dec to 19 Dec
€31
18 Dec - 19 Dec
includes taxes & fees
9.2/10 Wonderful! (7 reviews)

Frequently asked questions

What's the best place for a stay in Santa Isabel?
Hotel Lucerna Mexicali, located 7.5 mi (12.1 km) from the heart of Santa Isabel, is a top choice for your stay, based on our traveller data. Other good choices for your stay in the area are Hotel Araiza Mexicali and Real Inn Mexicali. See all available top hotels, or vacation rentals in Santa Isabel.
What are some of the best holiday rentals that Santa Isabel has to offer?
Casa Grande Los Laureles With Kids games, Plenty of open space.: This holiday home rental outside of Santa Isabel offers a balcony, a pool table and a BBQ to help you feel perfectly comfortable in your new surroundings. It has 4 bedrooms, as well as a kitchen with a fridge, a stovetop and a microwave, so that you can cook with friends or family. See all vacation rentals in Santa Isabel.
If I need to cancel my hotel reservation in Santa Isabel, will I receive a refund?
Yes! You'll find that most hotel room reservations are fully refundable if cancelled prior to the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of check in. If your reservation is non-refundable, it might still be possible to cancel it and get a refund within 24 hours of your booking. Filter your search by fully refundable to find flexible hotel deals in Santa Isabel.
What is staying in Santa Isabel like?
Visitors to Santa Isabel will definitely find plenty to explore and enjoy. There are 69 hotels and other accommodation options in the surrounding area. Find out more about Santa Isabel.
What is there to see in Santa Isabel?
Places to visit in the wider area include Mexicali Border Port I, City Forest and Zoo and Plaza Comercial La Cachanilla. You'll also find Eagles Nest Stadium and Imperial Valley Mall in the area. Take a look at what more there is to see and do in Expedia's Santa Isabel guide.
What's the seasonal weather like in Santa Isabel?
The hottest months are usually July and August, with an average temperature of 34°C, while the coldest months are December and January, with an average of 16°C. Average annual precipitation for Santa Isabel is 84 mm.

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