Santa Isabel Holidays

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    Save up to €900 when you book a flight and hotel together*

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    With over 300,000 hotels worldwide, it's easy to create a perfect package

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Top hotels in Santa Isabel

Hotel Araiza Mexicali

Hotel Araiza Mexicali

4 out of 5
Blvd. Benito Juarez 2220 Mexicali BC
Fully refundableReserve now, pay when you stay
The price is €115 per night from 8 Nov to 9 Nov
€115
8 Nov - 9 Nov
includes taxes & fees
Hotel Araiza Mexicali
Hotel Lucerna Mexicali

Hotel Lucerna Mexicali

4 out of 5
Boulevard Benito Juarez 2151 Mexicali BC
Fully refundableReserve now, pay when you stay
The price is €97 per night from 6 Dec to 7 Dec
€97
6 Dec - 7 Dec
includes taxes & fees
9.2/10 Wonderful! (1,815 reviews)
"Hi"

Reviewed on 4 Nov 2026

Hotel Lucerna Mexicali
Holiday Inn Mexicali Centro Civico by IHG

Holiday Inn Mexicali Centro Civico by IHG

3.5 out of 5
Av de los Heroes 201 Centro Cavico Mexicali BC
Fully refundable
The price is €120 per night from 6 Dec to 7 Dec
€120
6 Dec - 7 Dec
includes taxes & fees
Holiday Inn Mexicali Centro Civico by IHG
See all 80 properties in Santa Isabel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Santa Isabel holiday package cost?
You'll find cheap prices on Expedia for your Santa Isabel getaway. However, factors like the season, length of stay and your choice of hotel will influence how much your holiday to Santa Isabel costs.
What are the cheapest months to go to Santa Isabel?
January, February and August are great times to search for cheap Santa Isabel holiday packages. Opting to travel in less busy periods means you can generally find better prices on accommodation and flights.
How many days is enough for Santa Isabel?
With a well-organised travel plan, you can easily tick off the top Santa Isabel attractions in a few days. But if you prefer to discover lesser-known spots or take day trips, consider booking your Santa Isabel holiday for longer.
How to find the best Santa Isabel package deals?
Start your search for a Santa Isabel package deal by entering your preferred travel dates and destination under our "Packages" tab. Then apply a few filters, like "Guest rating" and "Property type," to tailor the results to your exact needs. You can also sort by "Package discount" and discover offers that come with irresistible savings. If you don't find the perfect Santa Isabel package deal straight away, simply tweak your dates and search again. Bear in mind that deals are only available for a limited time, so book early and get your Santa Isabel escape underway.
Is it cheaper to book a Santa Isabel holiday as a package?
Expedia holiday packages are designed to make your money go further. Bundle your flight, car rental and hotel into one great-value price and you could save hundreds of dollars. You'll generally land a better deal than booking each component individually. And you'll still have the flexibility to create a personalised Santa Isabel holiday by choosing your favourite accommodation type, airline and car class.
When to book a holiday package to Santa Isabel?
If you have your Santa Isabel holiday dates confirmed, book as soon as you can to grab some incredible deals. With Expedia, you can generally reserve some flights up to a year in advance. Prefer spontaneous adventures? Our last-minute deals are perfect for travelling on a whim.
How to plan a trip to Santa Isabel?

  1. Choose when to go: Check your diary and get your bags packed. Your favourite season and the available activities will also help you decide when to holiday in Santa Isabel.
  2. Plan your budget wisely: On top of the cost of your stay, you should factor in other expenses. These include flights, food and transportation. Also, set aside a little extra for unexpected expenses that could crop up during your trip to Santa Isabel.
  3. Set the duration of your trip: Start by listing all the attractions you'd like to get to in Santa Isabel. Then, estimate how long you'll need for each, along with any travel time.
  4. Bundle your bookings: With your travel dates in place, you can combine your hotels, flights, car rental and more into a tailored Santa Isabel holiday package.

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.