Santa María Department Holidays

  • Plan, book, travel with confidence

  • Better together

    Save up to €900 when you book a flight and hotel together*

  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package

  • Rest easy

    Plan, book, and manage your trip all in one place

Top hotels in Santa María Department

Patios de Cafayate - Wine Hotel & Restaurant

Patios de Cafayate - Wine Hotel & Restaurant

4 out of 5
Ruta Nacional 40 Y Ruta Provincial 68 Cafayate Salta
Fully refundableReserve now, pay when you stay
The price is €148 per night from 1 Jun to 2 Jun
€148
1 Jun - 2 Jun
9.6/10 Exceptional! (394 reviews)
Breakfast was awesome. Mountain views outstanding. Just needs a bit of a touch up on paint in some walls.

Reviewed on 30 Apr 2026

Patios de Cafayate - Wine Hotel & Restaurant
Piattelli Wine Resort

Piattelli Wine Resort

4.5 out of 5
Ruta Provincial 2 Km 3 Cafayate Salta
Fully refundableReserve now, pay when you stay
The price is €219 per night from 7 May to 8 May
€219
7 May - 8 May
9.8/10 Exceptional! (72 reviews)
Excelente hotel. Bellísima ubicación. Comida deliciosa. Estuvimos en varios hoteles y fue el mejor de todos en la zona. Repetible.

Reviewed on 26 Apr 2026

Piattelli Wine Resort
El Porvenir Wine Lodge

El Porvenir Wine Lodge

4.5 out of 5
Belgrano Cafayate Salta
Fully refundableReserve now, pay when you stay
The price is €134 per night from 1 Jun to 2 Jun
€134
1 Jun - 2 Jun
9.6/10 Exceptional! (32 reviews)
Beautiful location and resort❣️

Reviewed on 4 Apr 2026

El Porvenir Wine Lodge
See all 86 properties in Santa María Department
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Santa María Department holiday package cost?
We make it simple to travel somewhere new, with Santa María Department packages starting from just . You'll have the flexibility to combine your favourite hotels, airlines and car rental. For the ultimate getaway, why not add a few tours and experiences to your itinerary?
How do I get a cheap travel package to Santa María Department?
One of the easiest ways to save money (and time) is to bundle your bookings with Expedia. Flights, hotels, rental cars and activities — we've got it all. Pick and choose a combination that suits your style and see your savings grow. We know a package deal is never one-size-fits-all. That's why Expedia offers over 550 airlines and 1,000,000 properties worldwide, which lets you customize your Santa María Department holiday.
How far in advance should I book my Santa María Department holiday?
Savvy travellers book early. Air carriers typically advertise flight tickets up to a year ahead of departure, and this is an ideal opportunity to score some rock-bottom prices. Just been told you should take some holiday time in a few weeks? Don't fret. Expedia are never short on fantastic bargains to send you off on the getaway of your dreams, at an affordable price.
What does an Expedia Santa María Department travel package include?
Travel packages include hotels, rental cars and flights, but you can mix and match them to create your dream Santa María Department trip. You can also add on fun stuff like activities and tours once you've made your booking. You're in charge! When you bundle your bookings with Expedia, you'll enjoy deals you won't find elsewhere.
What should I know before booking a Santa María Department travel package?
You can save big by combining your flights, hotels and rental cars. Once you've created your package, add on fun stuff like day tours or experiences. Your next unforgettable adventure is only a couple of clicks away.
Can I choose my airline with a Santa María Department Expedia holiday package?
With a holiday package, you're always in charge. Whether you're hoping to fly to Santa María Department in first class or coach, simply choose from the available airline options. Expedia has access to more than 550 partner airlines worldwide.
If I'm not able to travel, can I cancel my Santa María Department holiday package?
You sure can, and we'll help you every step of the way. You may be able to cancel or amend your Santa María Department holiday package for free if you booked in the last 24 hours. But you may incur a fee from your hotel, airline or car rental company if you booked more than 24 hours ago. If your circumstances unexpectedly change, take a look at our Customer Service Portal for more information.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.