A coastal landscape with a wooden deck, lush green foliage, and a view of the ocean under a cloudy sky.

Santana Hotel Guide - Luxury Hotels in Santana, Cantagalo

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Santana Luxury Hotels

Our top choices for Santana luxury hotels

Front of property – evening/night

1. Roça Santo António Ecolodge Hotel

Roça Santo António Ecolodge Hotel
3.5 star property
Santana
8.4 out of 10, Very good, (16 reviews)
"Very friendly and helpful people. Great spot. It is out of the city so a good 'get away'. But you need your own vehicle."
United Kingdom
Anonymous traveller
The price is €224
includes taxes & fees
10 Nov - 11 Nov
Roça Santo António Ecolodge Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Santana Hotel Reviews

Frequently asked questions

Are you looking for a luxury hotel for your stay in Santana?
Use Expedia to help you arrange a flight to São Tomé Island (TMS-São Tomé Intl.) airport, and then choose from a variety of places to stay that will deliver the luxury you want. Amenities are important when you plan a holiday, so we make it easy to find what you need to make your stay special. If you want an upscale hotel that has a spa, an indoor pool or luxury bedding, Expedia can help you find the best luxury hotel experience that Santana offers.
When can I expect good weather in Santana?
Planning for the weather is a good way to make your trip to Santana relaxing and enjoyable, especially when you're splurging. The hottest months are usually March and April, with an average temperature of 28°C, while the coldest months are July and August, with an average of 25°C. The rainiest months in Santana are November, October, December and April, with each month seeing an average of 249 mm of rainfall.
What's there to see and do in Santana?
When you're in Santana, enjoy exploring the sights and attractions here including São Sebastião Museum, São Nicolau Waterfall and Pico São Tomé. If you have extra time while you're in the area, you might want to stop by Cloçon Téla Chocolate Factory and Estadio Nacional 12 de Julho.