Photo by Fabrice Récalt

Santana Hotels

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3 Dec - 4 Dec
Tomorrow
4 Dec - 5 Dec
This weekend
5 Dec - 7 Dec
Next weekend
12 Dec - 14 Dec

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Top 10 trending Santana hotels

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Omali São Tomé – Principe Collection

Omali São Tomé – Principe Collection

4.0 star property
São Tomé
9.4 out of 10, Exceptional, (61)
"The employees really make the property a superstar. "
United States
Mona
The price is €215
includes taxes & fees
11 Dec - 12 Dec
Omali São Tomé – Principe Collection
Outdoor pool
Pestana Miramar São Tomé

Pestana Miramar São Tomé

3.0 star property
São Tomé
7.2 out of 10, Good, (45)
"Very helpful and accommodating staff"
United States
sandra
The price is €145
includes taxes & fees
5 Dec - 6 Dec
Pestana Miramar São Tomé
Coffee shop
Hotel Central

Hotel Central

3.5 star property
São Tomé
8.2 out of 10, Very good, (24)
"Great value. Great location. Ok breakfast. Overall good value for money"
Norway
Elisabeth
Hotel Central
Lobby sitting area
Mucumbli Hotel

Mucumbli Hotel

3.0 star property
Neves
9.4 out of 10, Exceptional, (26)
"A bit rustier than i expected. Beds were SUPER sq "
Norway
Morten
The price is €130
includes taxes & fees
4 Dec - 5 Dec
Mucumbli Hotel
Lobby sitting area
SH Boutique Hotel

SH Boutique Hotel

3.5 star property
São Tomé
8.6 out of 10, Excellent, (10)
"Staff were very accommodating "
United States
Simon Peter
SH Boutique Hotel
Restaurant
Hotel Kenito

Hotel Kenito

2.5 star property
São Tomé
10.0 out of 10, Exceptional, (3)
"Exceptional"
United States
Nii Tetteh
The price is €90
includes taxes & fees
3 Jan - 4 Jan 2026
Hotel Kenito
Exterior
Hotel Kriola

Hotel Kriola

3.0 star property
São Tomé
9.0 out of 10, Wonderful, (4)
"Loved the mermaids in the pool"
United Kingdom
Eduardo Jorge Bettencourt da
Hotel Kriola
Outdoor pool
Pestana São Tomé

Pestana São Tomé

5.0 star property
Vila Maria
8.0 out of 10, Very good, (75)
"We had a very pleasant stay! The room was comfortable, the breakfast was great and the all around atmosphere of the place was nice. Beautiful views from the balcony of the room, and while having breakfast next to the ocean."
Norway
Richard
The price is €201
includes taxes & fees
5 Dec - 6 Dec
Pestana São Tomé
On the beach
Residêncial Tamarindos

Residêncial Tamarindos

3.0 star property
Guadalupe
8.6 out of 10, Excellent, (14)
"Couldn’t have had better hosts Perfect location for great hikes and waterfalls Many thanks to Marlena and Betty who made our visit memorable x"
United Kingdom
Maria
Residêncial Tamarindos
Poolside bar
Praia Accommodation

Praia Accommodation

3.0 star property
São Tomé
7.2 out of 10, Good, (17)
"Great place to stay "
United States
Daniel
Praia Accommodation
Outdoor pool, pool umbrellas, pool loungers
Hotel Praia

Hotel Praia

3.5 star property
São Tomé
7.6 out of 10, Good, (17)
"Solid, basic hotel. "
United States
Jonathan
Hotel Praia
Aerial view
N Guembú Nature Resort

N Guembú Nature Resort

3.0 star property
Malanza
7.8 out of 10, Good, (8)
"Very nice area and very friendly staff, who organized a trip to the island Ilhéu das Rolas with the Equator Monument. The beach on the left is fine for a swim. Good beds. Very good internet. "
Denmark
Dorte
N Guembú Nature Resort
Exterior
Casa de Ferias

Casa de Ferias

3.0 star property
São Tomé
9.6 out of 10, Exceptional, (4)
"I had a very good time here, got a lot of service and information from the family and in fact almost felt like a family member."
Sweden
Lars Roland
The price is €65
includes taxes & fees
29 Dec - 30 Dec
Casa de Ferias
Standard Cabin
CAMPISMO PRAIA GRANDE

CAMPISMO PRAIA GRANDE

1.0 star property
Malanza
8.6 out of 10, Excellent, (4)
"A little piece of paradise on an amazing beach. "
United Kingdom
John
The price is €54
includes taxes & fees
25 Dec - 26 Dec
CAMPISMO PRAIA GRANDE
Bungalow
Guest House Quinta Natural

Guest House Quinta Natural

3.0 star property
Trindade
10.0 out of 10, Exceptional, (1)
Guest House Quinta Natural
Exterior
Alojamento Santos Silva

Alojamento Santos Silva

3.0 star property
São Tomé
The price is €315
includes taxes & fees
3 Jan - 4 Jan 2026
Alojamento Santos Silva
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Learn more about Santana

Head to Estadio Nacional 12 de Julho and São Sebastião Museum—just two of the sights around Santana.

See all hotels in Santana
Isn’t this a nice place to have a breakfast!
Photo by Fabrice Récalt
Open Photo by Fabrice Récalt

Top Santana Hotel Reviews

Pestana São Tomé

Pestana São Tomé

10/10 Excellent
"Had a great time had a very nice view and great people working here."
Michael 2-night trip
Posted 3 weeks ago
Pestana São Tomé

More cheap stays in Santana

Sweet Guest House

Sweet Guest House

Vila Dolores n. 087 São Tomé
Get rates
8.6/10 Excellent! (44 reviews)

Frequently asked questions

Where is the best place to stay in Santana?
Based on our traveller data, Roça Santo António Ecolodge Hotel is one of the top choices for your stay. This hotel offers free breakfast and a restaurant. Pool and Beach Villa in Santana is another good choice for your visit. See all available top hotels, or vacation rentals in Santana.
What are some of the best holiday rentals that Santana has to offer?
Alojamento Santos Silva: This holiday home rental outside of Santana offers an outdoor pool, a garden and laundry facilities to help you feel perfectly comfortable in your new surroundings. Kitchen amenities include an oven, a microwave and kitchenware. Another good choice for your trip to Santana is endless horizon - Cozy house in charming Santana with WiFi. See all vacation rentals in Santana.
If I need to cancel my hotel reservation in Santana, will I receive a refund?
Yes! The majority of hotel bookings are fully refundable as long as you cancel prior to the hotel's cancellation deadline, which often is within 24-48 hours of check in. If you booked a non-refundable reservation, you may still be able to cancel and get a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Santana.
What's the best family accommodation in Santana?
Roça Santo António Ecolodge Hotel is a hotel with a children's pool and a restaurant, and it's a top choice on Expedia for families. Also, attractions in the area such as Cloçon Téla Chocolate Factory are fun for the whole family. Find more child-friendly accommodations in Santana.
What are some accommodation options with pools in Santana?
Roça Santo António Ecolodge Hotel is a top hotel with a children's pool, an outdoor pool and free buffet breakfast. View all hotels with pools in Santana.
How is it to stay in Santana?
Those travelling to Santana will definitely enjoy the sights to see and things to do. In Santana, there are 5 hotels and other accommodation options to choose from. Find out more about Santana.
What are the top places to visit in Santana?
Places to visit in the wider area include Estadio Nacional 12 de Julho, São Sebastião Museum and Pico São Tomé. You'll also find Palácio dos Congressos and São Nicolau Waterfall in the area. Take a look at what more there is to see and do in Expedia's Santana guide.
What's the weather like in Santana?
The hottest months are usually March and April, with an average temperature of 28°C, while the coldest months are July and August, with an average of 25°C. The rainiest months in Santana are November, October, December and April, with each month seeing an average of 249 mm of rainfall.

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