Santo Domingo de los Tsáchilas Holidays

  • Plan, book, travel with confidence

  • Better together

    Save up to €900 when you book a flight and hotel together*
  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package
  • Rest easy

    Plan, book, and manage your trip all in one place

Top hotels in Santo Domingo de los Tsáchilas

Hilton Colon Quito

Hilton Colon Quito

Amazonas N 1914 Y Patria Avenida 1 Quito
Fully refundableReserve now, pay when you stay
€86
18 Oct - 19 Oct
8.6/10 Excellent! (497 reviews)
"I liked everything from the hotel. The staff was friendly and professional. I highly recommend this hotel to everyone who visits Quito. I am planning to travel back to Quito by the beginning of 2026 and I will look forward to stay again on this hotel. Thank you for everything."

Reviewed on 20 Sept 2026

Hilton Colon Quito
Hotel Reina Isabel

Hotel Reina Isabel

Av. Amazonas N23-44 y Veintimilla Quito Pichincha
Fully refundableReserve now, pay when you stay
€86
28 Sept - 29 Sept
9/10 Wonderful! (1,001 reviews)
"Fue tan agradable nuestra estadía que decidimos alargar un día más nuestra estadía. Excelente en todos sus aspectos su atención. Lo recomendamos, por precio, atención y ubicación. Gracias."

Reviewed on 24 Sept 2026

Hotel Reina Isabel
Hotel Plaza Grande

Hotel Plaza Grande

Garcia Moreno N5-16 Y Chile Quito Pichincha
Fully refundableReserve now, pay when you stay
€176
29 Sept - 30 Sept
9.8/10 Exceptional! (265 reviews)
"Lovely hotel with exceptional service. Terrific value"

Reviewed on 11 Sept 2026

Hotel Plaza Grande
See all 544 properties in Santo Domingo de los Tsáchilas
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Santo Domingo de los Tsáchilas holiday package cost?
Handcraft your Santo Domingo de los Tsáchilas holiday package from as little as . Pick from any combination of rental cars, flights and hotels to craft the trip you've been dreaming about. Be sure to add on a few experiences or tours!
How do I get a cheap travel package to Santo Domingo de los Tsáchilas?
Imagine all the thrilling things you could do in Santo Domingo de los Tsáchilas with extra cash in your wallet. Watch your savings stack up when you bundle your hotel and airfare bookings into a Santo Domingo de los Tsáchilas holiday package. You have loads of choice when you book with Expedia too. In fact, you can pick from more than 550 airlines and 1,000,000 properties worldwide. Whether you're taking a holiday with the whole family or going it alone, planning a getaway to Santo Domingo de los Tsáchilas is better with a package.
What are the top hotels in Santo Domingo de los Tsáchilas?
If you're on your way to Santo Domingo de los Colorados, you can't go wrong with Grand Hotel Santander and Victoria Suites Hostal. Both are excellent bases for exploring this buzzing Santo Domingo de los Tsáchilas city.
How far in advance should I book my Santo Domingo de los Tsáchilas holiday?
While prices do change, we generally recommend booking your seats as soon as possible. Many international airfares are available on Expedia up to 12 months in advance. If you're booking late, you may still get lucky. Low prices to Santo Domingo de los Tsáchilas occasionally appear just weeks before departure.
What does an Expedia Santo Domingo de los Tsáchilas travel package include?
Rental cars, flights and hotels — we've got them all. With Expedia, you can shape your Santo Domingo de los Tsáchilas travel package the way you want. All you have to do is work out what you need. Once you've made your booking, you can add extras like activities and tours. The more you bundle, the more you save!
What should I know before booking a Santo Domingo de los Tsáchilas travel package?
A travel package can be more affordable than individually booking all you need for your adventure. For example, bundle your hotels, flights and rental cars and land a great deal. Whatever kind of holiday you're planning, there's bound to be a package to suit your budget.
Can I choose my airline with a Santo Domingo de los Tsáchilas Expedia holiday package?
Yes, you're in charge. We have access to over 550 airlines worldwide, so you can customize your Santo Domingo de los Tsáchilas getaway according to your budget and needs.
If I'm not able to travel, can I cancel my Santo Domingo de los Tsáchilas holiday package?
Yes, you can cancel your Santo Domingo de los Tsáchilas booking if your travel plans have been upended. Whether you'll be charged a fee or not depends on your airline, hotel or car rental company. You may be able to change or cancel your booking free of charge if you booked in the last 24 hours. Head to our Customer Service Portal for more information.

Stay near popular Santo Domingo de los Tsáchilas attractions

Parque Independencia

Explore the great outdoors at Parque Independencia, a lovely green space in Santo Domingo de los Colorados. Make some time to visit the spas while you're in the area.
See properties

What to do in Santo Domingo de los Tsáchilas

Mindo Ziplines Tour, offers a 10-wire tour through the cloud forest where you can enjoy adventure, nature, adrenaline.

Mindo Ziplines Tours / Canopy Tour / Zip Line

€18
per adult
Mindo Ziplines Tours / Canopy Tour / Zip Line
Tour of hummingbirds in Mindo

Chaquimallana Reserve : Mindo's Best Hummingbird Experience.

€4
per adult
Chaquimallana Reserve : Mindo's Best Hummingbird Experience.
Mindo Adventure.

Mindo: Bird watching, Chocolate, Waterfall and Adventure

€65
per adult
100% of travellers recommend
Mindo: Bird watching, Chocolate, Waterfall and Adventure
See all activities in Santo Domingo de los Tsáchilas
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.