Seneca Holidays
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Where to stay in Seneca
Find the best Seneca areas and neighborhoods for the activities you enjoy most. Learn more about Seneca
Serenity Bay
When in Serenity Bay, you can plan a visit to Keowee Key Golf Course and Lake Keowee, some noteworthy sights in the nearby area.
Top hotels in Seneca
Lakeside Lodge Clemson
13500 Clemson Blvd Seneca SC
Fully refundableReserve now, pay when you stay
The price is €115 per night from 6 Jan to 7 Jan
€115
6 Jan - 7 Jan
includes taxes & fees
8.8/10 Excellent! (1,000 reviews)
Enjoyed our stay.
Reviewed on 15 Dec 2025
Tru by Hilton Seneca Clemson
13050 Clemson Blvd Seneca SC
Fully refundableReserve now, pay when you stay
The price is €99 per night from 11 Jan to 12 Jan
€99
11 Jan - 12 Jan
includes taxes & fees
9.2/10 Wonderful! (800 reviews)
Breakfast was typical but the staff was very friendly and helpful. Nice clean room, safe area close to Clemson University.
Reviewed on 28 Dec 2025
Quality Inn Seneca Clemson Area US-123
226 Hi Tech Rd Seneca SC
Fully refundableReserve now, pay when you stay
The price is €74 per night from 25 Jan to 26 Jan
€74
25 Jan - 26 Jan
includes taxes & fees
7.8/10 Good! (666 reviews)
Good available parking. Room clean. Breakfast was minimal, but good. The tub was slippery and needed a mat. I almost fell a couple of times. I would stay here again.
Reviewed on 29 Dec 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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