Siesta Isle Holidays

  • Plan, book, travel with confidence

  • Better together

    Save up to €185 when you book a flight and hotel together*

  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package

  • Rest easy

    Plan, book, and manage your trip all in one place
Price found within the past 48 hours. Click for updated prices.
Lani Kai Beachfront Resort

Lani Kai Beachfront Resort

3.5 out of 5
Price was €503, price is now €463 per person
€463
per person
8 Jan - 10 Jan
found 22 hours ago
Return flight included
Toronto (YYZ) to Fort Myers (RSW)
17.6/10 Exceptional! (1,027 reviews)
Courteous staff. Rooms were clean. Some

Reviewed on 13 Nov 2025

Where to stay in Siesta Isle

Find the best Siesta Isle areas and neighborhoods for the activities you enjoy most. Learn more about Siesta Isle
Default Image

Mid Island

1 out of top 10 points of interest in this area
4.5/5(2 area reviews)

While visiting Mid Island, you might make a stop by sights like Estero Boulevard Beach and Sterling Ave Beach.

Find hotels in Mid Island

Top hotels in Siesta Isle

Latitude 26 Waterfront Boutique Resort - Fort Myers Beach

Latitude 26 Waterfront Boutique Resort - Fort Myers Beach

2.5 out of 5
17990 San Carlos Blvd, Fort Myers Beach, FL
Fully refundableReserve now, pay when you stay
The price is €94 per night from 16 Nov to 17 Nov
€94
16 Nov - 17 Nov
includes taxes & fees
8.6/10 Excellent! (1,004 reviews)
Super nice boutique hotel Love the atmosphere The bikes and kayaks free to use The dock and fire pits

Reviewed on 9 Nov 2025

Latitude 26 Waterfront Boutique Resort - Fort Myers Beach
Margaritaville Beach Resort Fort Myers

Margaritaville Beach Resort Fort Myers

4 out of 5
251 Crescent Street Fort Myers Beach FL
The price is €206 per night from 17 Nov to 18 Nov
€206
17 Nov - 18 Nov
includes taxes & fees
8.8/10 Excellent! (1,609 reviews)
Yes

Reviewed on 7 Nov 2025

Margaritaville Beach Resort Fort Myers
Lani Kai Beachfront Resort

Lani Kai Beachfront Resort

3.5 out of 5
1400 Estero Blvd Fort Myers Beach FL
Fully refundableReserve now, pay when you stay
The price is €229 per night from 16 Nov to 17 Nov
€229
16 Nov - 17 Nov
includes taxes & fees
8.8/10 Excellent! (1,013 reviews)
Friendly staff, room was clean, easy to find parking (but you have to pay for parking even if you are a guest of the hotel). Parking is in addition to a resort fee. They responded to our questions right away. Great atmosphere with music. I wish the information was updated that the sunroof deck bar ...

Reviewed on 9 Nov 2025

Lani Kai Beachfront Resort
See all 17,400 properties in Siesta Isle
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Siesta Isle holiday package cost?
Starting from only €463, a package is your ticket to cheap travel. Create your own Siesta Isle adventure by selecting from our comprehensive range of flights, hotels and rental cars.
How do I get a cheap travel package to Siesta Isle?
Find flights that fit your schedule, add a hotel to your booking and see how much you save with a Siesta Isle holiday package. It's as easy as that! From flights and hotels to rental cars and tours, Expedia is where your cheap holiday begins. And with over 550 partner airlines and 1,000,000 hotel options worldwide to pick from, you'll never be short of choice.
Where should I stay in Siesta Isle?
With interesting attractions like Key West Express and Fishing Pier Fort Myers Beach in this neighbourhood, see if you can find a hotel near either one. Bunche Beach is another sight that lures the crowds.
What are the top hotels in Siesta Isle?
If it's your first time in Siesta Isle, secure a room at Latitude 26 Waterfront Boutique Resort - Fort Myers Beach or House Was Not Affected By Hurricane Ian. Still Renting. Both hotels offer comfy beds and are favourites with lots of travellers.
How far in advance should I book my Siesta Isle holiday?
The earlier you book, the better. Airlines usually advertise flights up to a year in advance, and this is a great opportunity to land some rock-bottom prices. Boss just told you to use up your holiday time next week? No need to worry. Expedia are never short on fantastic bargains to send you off on the getaway of your dreams, at an affordable price.
What does an Expedia Siesta Isle travel package include?
Flights, rental cars and hotels — you'll find them all here. With Expedia, you can shape your Siesta Isle travel package just the way you want. All you have to do is decide what you need. Once you've made your booking, you can add on extras like activities and tours. The more you bundle, the more you save!
What should I know before booking a Siesta Isle travel package?
A travel package can be tailored to your budget and is a terrific way to make your budget go further. What you include is completely up to you. Rental cars, hotels and flights — come up with a combination that works with your plans.
Can I choose my airline with a Siesta Isle Expedia holiday package?
You certainly can. We have more than 550 airline partners worldwide, so select the carrier that fits your budget and travelling style.
If I'm not able to travel, can I cancel my Siesta Isle holiday package?
It's difficult to predict what the future holds, so it's good to know that you can change or cancel your Siesta Isle holiday package. If your booking was made in the last 24 hours, you may be eligible for a refund. If your booking is older, your airline, hotel or car rental company may charge a fee. Visit our Customer Service Portal for more information.

Popular places to visit

Ostego Bay Marine Science Center

You can spend time browsing the exhibits at Ostego Bay Marine Science Center in Fort Myers Beach. Stroll along the beautiful beaches in this family-friendly area or visit its lively bars.

Ostego Bay Marine Science Center

Things to do

Copacetic Day Sail

Copacetic Day Sail

€60
per adult
100% of travellers recommend
Copacetic Day Sail
Southwest Florida Sunset Sail

Southwest Florida Sunset Sail

€60
per adult
100% of travellers recommend
Southwest Florida Sunset Sail
Dolphin Wildlife Cruise Fort Myers Beach

Dolphin Wildlife Cruise Fort Myers Beach

€55
per adult
Dolphin Wildlife Cruise Fort Myers Beach
See all activities in Fort Myers Beach
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.