Holiday Rentals in St. Charles

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Our top choices for St. Charles holiday rentals

Walk to St. Charles Entertainment

Walk to St. Charles Entertainment
Saint Charles
9.0 out of 10, Wonderful, (10 reviews)
"We really enjoyed our stay. The house was clean, spacious, and very accommodating. We stayed for a dance competition and the proximity to the convention center was unbeatable. "
United States
Chloe
The price is €252
includes taxes & fees
19 Apr - 20 Apr
Walk to St. Charles Entertainment

Charming open 4bd and screen-in porch! Sleeps 10!

Charming open 4bd and screen-in porch! Sleeps 10!
Saint Charles
9.2 out of 10, Wonderful, (36 reviews)
"House had everything we needed, and was very well organized! Would definitely recommend!"
United States
Tim W.
The price is €426
includes taxes & fees
20 Apr - 21 Apr
Charming open 4bd and screen-in porch! Sleeps 10!

Aunt Doodle’s House 8 blocks from Historic Main Street.. Convenient location!

Aunt Doodle’s House 8 blocks from Historic Main Street.. Convenient location!
St. Charles Historic District
9.6 out of 10, Exceptional, (75 reviews)
"Great communication from host, cute house in an awesome location. Will definitely be staying again!"
United States
Sydney W.
The price is €189
includes taxes & fees
19 Apr - 20 Apr
Aunt Doodle’s House 8 blocks from Historic Main Street.. Convenient location!

Duplex Hideaway in St. Charles, MO

Duplex Hideaway in St. Charles, MO
St. Charles Historic District
10.0 out of 10, Exceptional, (5 reviews)
"I will stay here again. It was a great location for my visit. Lots of room and amenities. Highly recommend this location if you are visiting the St Louis area. Barely a mile to get to Hwy 70, so easy access to St Louis, St Peter's, Wentzville etc. Maybe two blocks from Historic St Charles and Ameristar Casino."
United States
Karen M.
The price is €204
includes taxes & fees
20 Apr - 21 Apr
Duplex Hideaway in St. Charles, MO

Spacious 2 Bedroom Townhome

Spacious 2 Bedroom Townhome
Saint Charles
8.0 out of 10, Very good, (14 reviews)
"The stay here was amazing!! Live the little townhouse so much. Host was amazing!!"
United States
Tina W.
The price is €247
includes taxes & fees
20 Apr - 21 Apr
Spacious 2 Bedroom Townhome

St. Charles Manor | 4BR Getaway Home+HotTub+GameRm .6 acres

St. Charles Manor | 4BR Getaway Home+HotTub+GameRm .6 acres
Saint Charles
10.0 out of 10, Exceptional, (5 reviews)
"Wonderful place to stay for a group trip! Lots of space and activities for everyone to do. The hosts are very accommodating and quick to respond for any last minute questions. "
United States
Scott S.
The price is €632
includes taxes & fees
19 Apr - 20 Apr
St. Charles Manor | 4BR Getaway Home+HotTub+GameRm .6 acres

The Original Custom House!

The Original Custom House!
St. Charles Historic District
9.6 out of 10, Exceptional, (37 reviews)
"The location is excellent. "
United States
McRay H.
The price is €302
includes taxes & fees
20 Apr - 21 Apr
The Original Custom House!

Main Street Balcony Apartment

Main Street Balcony Apartment
St. Charles Historic District
9.6 out of 10, Exceptional, (36 reviews)
"Great location for shopping and a lot of restaurants nearby. Beds were very comfortable. "
United States
Brooke I.
The price is €367
includes taxes & fees
19 Apr - 20 Apr
Main Street Balcony Apartment

Stay on Main Historic Studio

Stay on Main Historic Studio
St. Charles Historic District
9.0 out of 10, Wonderful, (34 reviews)
"Nice property.. Clean. "
United States
Belinda J.
The price is €169
includes taxes & fees
19 Apr - 20 Apr
Stay on Main Historic Studio

New Remodel in St. Charles - Sleeps 10! New patio! Large Fenced-in backyard!

New Remodel in St. Charles - Sleeps 10! New patio! Large Fenced-in backyard!
St. Charles Historic District
9.6 out of 10, Exceptional, (70 reviews)
"Very clean and comfortable. Enjoyed our stay"
United States
Dana S.
New Remodel in St. Charles - Sleeps 10! New patio! Large Fenced-in backyard!

Amazing Renovated Historic Loft on Main Street

Amazing Renovated Historic Loft on Main Street
St. Charles Historic District
10.0 out of 10, Exceptional, (59 reviews)
"Lovely accommodations, very clean, well equipped, great location. "
United States
Emily B.
The price is €237
includes taxes & fees
19 Apr - 20 Apr
Amazing Renovated Historic Loft on Main Street

1st Capitol Mansion - Suite 401

1st Capitol Mansion - Suite 401
St. Charles Historic District
7.6 out of 10, Good, (8 reviews)
"Nice property and a great location to all the shops and restaurants that St. Charles has to offer. The place was clean and nicely updated. Will definitely stay here again!"
United States
Emily L.
The price is €259
includes taxes & fees
30 Apr - 1 May
1st Capitol Mansion - Suite 401

The Bourbon & Brass | Speakeasy-Inspired 2BDR

The Bourbon & Brass | Speakeasy-Inspired 2BDR
St. Charles Historic District
8.0 out of 10, Very good, (1 review)
"Room was fantastic! The grounds need to be cleaned up a bit."
United States
Marilyn
The price is €273
includes taxes & fees
30 Apr - 1 May
The Bourbon & Brass | Speakeasy-Inspired 2BDR

2 Bdr Upstairs Apt Walking Distance to Main St

2 Bdr Upstairs Apt Walking Distance to Main St
Saint Charles
7.6 out of 10, Good, (4 reviews)
"The best price-value ratio. Quiet neighborhood, close to the city center."
United States
Tamas P.
The price is €249
includes taxes & fees
17 Apr - 18 Apr
2 Bdr Upstairs Apt Walking Distance to Main St

Spacious, Beautiful St. Charles Home-Remodeled-Sleeps 10! New Patio!

Spacious, Beautiful St. Charles Home-Remodeled-Sleeps 10! New Patio!
St. Charles Historic District
9.8 out of 10, Exceptional, (60 reviews)
"The booking was easy and the host attentive. No problem with the stay. Would stay again!"
United States
Andrew K.
Spacious, Beautiful St. Charles Home-Remodeled-Sleeps 10! New Patio!

The Historic Bricks on Main

The Historic Bricks on Main
St. Charles Historic District
9.0 out of 10, Wonderful, (17 reviews)
"Host was very welcoming and helpful when we have any questions no matter what time of day. The place was very quaint and comfy. We would highly recommend. "
United States
Chelsea L.
The price is €215
includes taxes & fees
30 Apr - 1 May
The Historic Bricks on Main

Stylish1BRStudioCleanQuietandCozy

Stylish1BRStudioCleanQuietandCozy
Saint Charles
The price is €215
includes taxes & fees
4 May - 5 May
Stylish1BRStudioCleanQuietandCozy

The Lofts of North Main Street

The Lofts of North Main Street
St. Charles Historic District
9.6 out of 10, Exceptional, (168 reviews)
"Host was very responsive and location was perfect"
United States
Peggy K.
The price is €224
includes taxes & fees
22 Apr - 23 Apr
The Lofts of North Main Street

Historic Main St. Customs House Upstairs Apartment

Historic Main St. Customs House Upstairs Apartment
St. Charles Historic District
9.6 out of 10, Exceptional, (36 reviews)
"Great Stay and great location! "
United States
Angela
The price is €302
includes taxes & fees
21 Apr - 22 Apr
Historic Main St. Customs House Upstairs Apartment

Cottage on Historic Main Street- Low Cleaning fee

Cottage on Historic Main Street- Low Cleaning fee
St. Charles Historic District
10.0 out of 10, Exceptional, (12 reviews)
"A very quiet, clean and relaxing stay. "
United States
Dora S.
The price is €215
includes taxes & fees
21 Apr - 22 Apr
Cottage on Historic Main Street- Low Cleaning fee
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top St. Charles Hotel Reviews

Find out more about St. Charles

Everything you need to know about St. Charles holiday rentals

Whether you’re excited for the perfect family holiday, a romantic getaway for two, or the ultimate city break, we’ve got the St. Charles holiday rental for you. At Expedia, you can take your pick from private holiday homes, apartments, cottages, apart-hotels, cabins, villas... The list goes on, and on… and on!

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect St. Charles holiday rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search. 

St. Charles holiday rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in St. Charles. If you’re looking for a little peace, consider booking during the quieter months, such as  . For more hustle and bustle, you may prefer to visit in . 

Prices vary throughout the year and depends on the property type. Your chosen location and amenities will impact the cost of your trip, too. A St. Charles holiday rental often works out to be a fantastic, cost-effective option for groups and families visiting for a few nights or longer. And if a hotel room is just too small, get a holiday rental with multiple bedrooms and shared living spaces to kick back in.  The selection of St. Charles holiday rentals we have selected for you start as low as €105 per night. Entering your travel dates in the search wizard you might find even better deals!

How to find incredible deals on St. Charles rentals

At Expedia, we put the best St. Charles holiday rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia. 

To find some top St. Charles rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream St. Charles holiday.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around St. Charles. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence. 

Frequently asked questions

Can I find holiday rentals in St. Charles?

Yes, there are holiday rentals close to the most popular sights in St. Charles, or you can select a more secluded option if you're looking for a relaxing stay. Tourists like the array of shops and top-notch restaurants in St. Charles. The live music and theatre scene are some other things you might like to check out during your trip.

What are some of the best holiday rentals that St. Charles has to offer?

St. Charles 1860's Gem - Sleeps 6!: This highly rated holiday home rental in St. Charles is located on a river, and has a garden, a selection of books and air conditioning to put you at ease in your new surroundings. Kitchen amenities include a dishwasher, a fridge and a stovetop.

How many holiday rentals are there in St. Charles?

Expedia has 86 holiday rentals for your stay in St. Charles.

What can I see and do in St. Charles?

Katy Trail and Mississippi River are a couple of scenic spots to enjoy the outdoors, whereas Missouri Artists on Main is one of the cultural attractions. Other places in town to visit include Historic Main Street and Lewis & Clark Boathouse and Nature Center.

What are holiday rentals like in St. Charles?

Holiday rentals are privately owned properties you can book for a few days, or a quick weekend, in St. Charles. Holiday rentals provide amenities like laundry facilities and kitchens so you'll feel just like you're staying in your own home. If you're concerned about a sanitised environment, holiday rentals can offer a sense of security away from shared hotel lifts and busy front desks while still allowing you the experience of travel. You'll also have more space in a holiday rental than in a hotel, which makes a holiday rental a great choice for a family getaway.