
Defiance Hotels
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Our top choices for Defiance hotels

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
Heritage Inn & Suites St. Louis/Fenton, Trademark by WyndhamFenton
8.0 out of 10, Very good, (1,195 reviews)
The price is €88
includes taxes & fees
12 Apr - 13 Apr

Baymont by Wyndham Warrenton
Baymont by Wyndham WarrentonWarrenton
7.6 out of 10, Good, (1,001 reviews)
The price is €72
includes taxes & fees
12 Apr - 13 Apr

Wingate by Wyndham St. Louis/Fenton Route 66
Wingate by Wyndham St. Louis/Fenton Route 66Fenton
7.8 out of 10, Good, (1,191 reviews)
The price is €84
includes taxes & fees
13 Apr - 14 Apr

Sleep Inn & Suites O'Fallon MO - Technology Drive
Sleep Inn & Suites O'Fallon MO - Technology DriveO'Fallon
9.0 out of 10, Wonderful, (1,001 reviews)
The price is €83
includes taxes & fees
14 Apr - 15 Apr

Super 8 by Wyndham Warrenton
Super 8 by Wyndham WarrentonWarrenton
7.4 out of 10, Good, (640 reviews)
The price is €51
includes taxes & fees
26 Apr - 27 Apr

WoodSpring Suites St Peters-OFallon
WoodSpring Suites St Peters-OFallonSt. Peters
8.8 out of 10, Excellent, (76 reviews)
The price is €90
includes taxes & fees
12 Apr - 13 Apr

Quality Inn Foristell
Quality Inn ForistellForistell
8.2 out of 10, Very good, (966 reviews)
The price is €86
includes taxes & fees
6 May - 7 May

Best Western Plus Fenton
Best Western Plus FentonFenton
9.2 out of 10, Wonderful, (259 reviews)
The price is €98
includes taxes & fees
16 Apr - 17 Apr

The Wildwood Hotel
The Wildwood HotelWildwood
9.2 out of 10, Wonderful, (1,629 reviews)
The price is €88
includes taxes & fees
13 Apr - 14 Apr

Comfort Suites St Charles - St Louis
Comfort Suites St Charles - St LouisSt. Charles
8.4 out of 10, Very good, (1,010 reviews)
The price is €87
includes taxes & fees
10 May - 11 May

Hampton Inn St. Louis Wentzville
Hampton Inn St. Louis WentzvilleWentzville
9.0 out of 10, Wonderful, (688 reviews)
The price is €132
includes taxes & fees
26 Apr - 27 Apr

Hampton Inn St. Charles St. Peters
Hampton Inn St. Charles St. PetersSt. Charles
8.0 out of 10, Very good, (1,006 reviews)
The price is €112
includes taxes & fees
3 May - 4 May

Fairfield Inn & Suites Wentzville
Fairfield Inn & Suites WentzvilleWentzville
9.0 out of 10, Wonderful, (669 reviews)
The price is €125
includes taxes & fees
16 Apr - 17 Apr

Holiday Inn Express & Suites Wentzville St Louis West by IHG
Holiday Inn Express & Suites Wentzville St Louis West by IHGWentzville
9.4 out of 10, Exceptional, (891 reviews)
The price is €146
includes taxes & fees
26 Apr - 27 Apr

Super 8 by Wyndham Washington
Super 8 by Wyndham WashingtonWashington
8.4 out of 10, Very good, (717 reviews)
The price is €84
includes taxes & fees
22 Apr - 23 Apr

Best Western Plus Washington Hotel
Best Western Plus Washington HotelWashington
9.2 out of 10, Wonderful, (672 reviews)
The price is €125
includes taxes & fees
20 Apr - 21 Apr

Cedar Creek
Cedar CreekNew Haven
9.0 out of 10, Wonderful, (265 reviews)
The price is €132
includes taxes & fees
12 Apr - 13 Apr

Drury Inn & Suites Southwest St. Louis
Drury Inn & Suites Southwest St. LouisValley Park
9.6 out of 10, Exceptional, (1,013 reviews)
The price is €111
includes taxes & fees
10 May - 11 May

Courtyard by Marriott St. Louis St. Peters
Courtyard by Marriott St. Louis St. PetersSt. Peters
9.0 out of 10, Wonderful, (704 reviews)
The price is €108
includes taxes & fees
19 Apr - 20 Apr

Comfort Inn & Suites St. Louis - O'Fallon
Comfort Inn & Suites St. Louis - O'FallonO'Fallon
7.6 out of 10, Good, (1,002 reviews)
The price is €79
includes taxes & fees
6 May - 7 May
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Stay near popular Defiance attractions
Learn more about Defiance
Nestled along the Missouri River, this historic village offers scenic hiking trails and access to nearby wine country. Visit the Daniel Boone Home in neighbouring Defiance Township or enjoy tastings at the family-owned wineries dotting the surrounding countryside.

Top Defiance Hotel Reviews

Ameristar Casino Resort and Spa
2/10 Terrible
More cheap stays in Defiance

Relax Inn Saint Charles
3800 Harry S Truman Blvd St. Charles MO
The price is €62 per night from 25 Apr to 26 Apr
€62
25 Apr - 26 Apr
includes taxes & fees
6.8/10 (1,003 reviews)
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- Centene Community Ice Center
- Chandler Hill Vineyards
- Visit Crestwood
- Defiance Holidays
- Fenton Holidays
- Grant's Farm
- Visit Harvester
- Kirkwood Park
- Labadie Holidays
- Laumeier Sculpture Park
- Magic House - St. Louis Children's Museum
- Payne-Gentry Historical House
- Robertsville State Park
- Route 66 State Park
- Saint Louis Galleria Mall
- Sky Zone Indoor Trampoline Park - St. Louis
- Spooner's Frozen Custard
- St. Jordan Creek Winery
- St. Louis Car Museum
- Visit Edmundson
- St. Peters Holidays
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- Wentzville Holidays
- Woodbine Center Shopping Center
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