Defiance Hotels
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Family friendly
Check prices for these dates
Top 10 trending Defiance hotels

The Wildwood Hotel
Wildwood
9.2 out of 10, Wonderful, (1609)

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
Fenton
8.0 out of 10, Very good, (1029)
The price is €85
includes taxes & fees
7 Dec - 8 Dec

Best Western Plus St. Louis West-Westport
Maryland Heights
8.0 out of 10, Very good, (1023)
The price is €99
includes taxes & fees
1 Dec - 2 Dec

Baymont by Wyndham Warrenton
Warrenton
7.4 out of 10, Good, (1003)
The price is €83
includes taxes & fees
5 Dec - 6 Dec

Sonesta ES Suites St. Louis - Chesterfield
Chesterfield
8.0 out of 10, Very good, (1030)
The price is €93
includes taxes & fees
11 Dec - 12 Dec

AC Hotel by Marriott St. Louis Chesterfield
Chesterfield
9.2 out of 10, Wonderful, (231)
The price is €119
includes taxes & fees
21 Dec - 22 Dec
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Stay near popular Defiance attractions
Learn more about Defiance
Nestled along the Missouri River, this historic village offers scenic hiking trails and access to nearby wine country. Visit the Daniel Boone Home in neighbouring Defiance Township or enjoy tastings at the family-owned wineries dotting the surrounding countryside.

Top Defiance Hotel Reviews

Embassy Suites by Hilton St. Louis St. Charles
10/10 Excellent
More cheap stays in Defiance

Relax Inn Saint Charles
3800 Harry S Truman Blvd St. Charles MO
The price is €62 per night from 1 Dec to 2 Dec
€62
1 Dec - 2 Dec
includes taxes & fees
6.4/10 (1,006 reviews)
Frequently asked questions
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Near an Airport
Hotels Near Defiance, St. Louis
- St. Charles Hotels
- Chesterfield Hotels
- Maryland Heights Hotels
- St. Peters Hotels
- Innsbrook Hotels
- O'Fallon Hotels
- Wentzville Hotels
- Fenton Hotels
- Kirkwood Hotels
- Washington Hotels
- Eureka Hotels
- Bridgeton Hotels
- Ozarks Hotels
- Hazelwood Hotels
- Wildwood Hotels
- Florissant Hotels
- Ballwin Hotels
- Warrenton Hotels
- Valley Park Hotels
- Troy Hotels
More top Defiance Hotels
- Courtyard by Marriott St Louis Creve Coeur
- Best Western Plus St. Louis West-Westport
- La Quinta Inn & Suites by Wyndham St. Louis Westport
- Hampton Inn St. Charles St. Peters
- Country Inn & Suites by Radisson, St. Charles Historic District
- Best Western Plus The Charles Hotel
- Embassy Suites by Hilton St. Louis St. Charles
- Drury Inn & Suites Southwest St. Louis
- Hyatt Place St. Louis/Chesterfield
- Relax Inn Saint Charles
- Drury Plaza Hotel St. Louis Chesterfield
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