Defiance Hotels

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Check prices for these dates

Next weekend
5 Jun - 7 Jun
In two weeks
12 Jun - 14 Jun

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Our top choices for Defiance hotels

Indoor pool

Baymont by Wyndham Warrenton

Baymont by Wyndham Warrenton
2.5 star property
Warrenton
7.6 out of 10, Good, (1,002 reviews)
"Excellent place to stay!"
United States
Steven
The price is €72
includes taxes & fees
7 Jun - 8 Jun
Baymont by Wyndham Warrenton
Exterior

WoodSpring Suites St Peters-OFallon

WoodSpring Suites St Peters-OFallon
2.5 star property
St. Peters
8.6 out of 10, Excellent, (136 reviews)
"Overall a good stay. Would stay there again."
United States
Roxanne
The price is €75
includes taxes & fees
22 Jun - 23 Jun
WoodSpring Suites St Peters-OFallon
Lobby

Quality Inn Foristell

Quality Inn Foristell
2.5 star property
Foristell
8.2 out of 10, Very good, (1,007 reviews)
"Staff was helpful, area was easy tp navigate. Place was great for the price"
United States
Ryan
The price is €86
includes taxes & fees
31 May - 1 Jun
Quality Inn Foristell
Lobby

Super 8 by Wyndham Warrenton

Super 8 by Wyndham Warrenton
2.0 star property
Warrenton
7.4 out of 10, Good, (651 reviews)
"Terrific staff very helpful manager"
United States
Dale
The price is €58
includes taxes & fees
7 Jun - 8 Jun
Super 8 by Wyndham Warrenton
Reception

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
3.0 star property
Fenton
7.8 out of 10, Good, (1,310 reviews)
"Would stay here again."
United States
Randy
The price is €99
includes taxes & fees
1 Jun - 2 Jun
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
Premium bedding, desk, iron/ironing board, free WiFi

Sleep Inn & Suites O'Fallon MO - Technology Drive

Sleep Inn & Suites O'Fallon MO - Technology Drive
2.5 star property
O'Fallon
9.0 out of 10, Wonderful, (1,007 reviews)
"Everything was excellent, location amenities, food.."
United States
FERNANDO
The price is €83
includes taxes & fees
3 Jun - 4 Jun
Sleep Inn & Suites O'Fallon MO - Technology Drive
43-inch LED TV with digital channels, TV

Comfort Inn & Suites St. Louis - O'Fallon

Comfort Inn & Suites St. Louis - O'Fallon
2.5 star property
O'Fallon
7.6 out of 10, Good, (1,000 reviews)
"Quiet and wood's surroundings nice place"
United States
Matthew
The price is €91
includes taxes & fees
21 Jun - 22 Jun
Comfort Inn & Suites St. Louis - O'Fallon
Property entrance

The Wildwood Hotel

The Wildwood Hotel
3.5 star property
Wildwood
9.2 out of 10, Wonderful, (1,654 reviews)
"Great place to stay, met my needs. "
United States
kathy
The price is €84
includes taxes & fees
22 Jun - 23 Jun
The Wildwood Hotel
Room, 2 Queen Beds, Non Smoking

Wingate by Wyndham St. Louis/Fenton Route 66

Wingate by Wyndham St. Louis/Fenton Route 66
3.0 star property
Fenton
7.8 out of 10, Good, (1,232 reviews)
"Lots of food choices and gas stations near by also very easy highway access"
United States
Daquana
The price is €88
includes taxes & fees
2 Jun - 3 Jun
Wingate by Wyndham St. Louis/Fenton Route 66
Front of property – evening/night

Cedar Creek

Cedar Creek
3.0 star property
New Haven
9.0 out of 10, Wonderful, (270 reviews)
"Nice quiet stay for nearby wedding. "
United States
joan
The price is €133
includes taxes & fees
30 Jun - 1 Jul
Cedar Creek
Lobby

Drury Inn & Suites St. Louis St. Peters

Drury Inn & Suites St. Louis St. Peters
3.0 star property
St. Peters
9.4 out of 10, Exceptional, (1,003 reviews)
"Great location and clean hotel!"
United States
Admir
The price is €108
includes taxes & fees
7 Jun - 8 Jun
Drury Inn & Suites St. Louis St. Peters
Free daily buffet breakfast

Best Western Plus Fenton

Best Western Plus Fenton
2.5 star property
Fenton
9.2 out of 10, Wonderful, (309 reviews)
"Staff and breakfast were amazing!"
United States
Shilo
The price is €103
includes taxes & fees
2 Jun - 3 Jun
Best Western Plus Fenton
Lobby

Best Western Plus Washington Hotel

Best Western Plus Washington Hotel
2.5 star property
Washington
9.2 out of 10, Wonderful, (688 reviews)
"Very clean and staff were friendly. Breakfast was good and will definitely stay here again. "
United States
Rod
The price is €126
includes taxes & fees
2 Jun - 3 Jun
Best Western Plus Washington Hotel
Lobby

Super 8 by Wyndham Union

Super 8 by Wyndham Union
2.0 star property
Union
8.2 out of 10, Very good, (662 reviews)
"Enjoyed my stay!!!"
United States
TINA
The price is €80
includes taxes & fees
7 Jun - 8 Jun
Super 8 by Wyndham Union
Family Studio Suite (No Elevator Access)

River Sirens Hotel

River Sirens Hotel
2.5 star property
Washington
9.8 out of 10, Exceptional, (199 reviews)
"We love the theme, the hotel was clean and we love that we could walk down to the alley and play arcade games and have a beer and we love the breakfast voucher as well. What a neat place to stay."
United States
Natalie
The price is €101
includes taxes & fees
31 May - 1 Jun
River Sirens Hotel
Lobby

Quality Inn Near Six Flags St. Louis

Quality Inn Near Six Flags St. Louis
2.5 star property
Pacific
8.4 out of 10, Very good, (382 reviews)
"Great last minute booking when we needed to get off the road after a long day."
United States
Brent
The price is €102
includes taxes & fees
2 Jun - 3 Jun
Quality Inn Near Six Flags St. Louis
Exterior

Comfort Suites St Charles - St Louis

Comfort Suites St Charles - St Louis
2.5 star property
St. Charles
8.4 out of 10, Very good, (1,000 reviews)
"Good nice place"
United States
Cathy
The price is €97
includes taxes & fees
7 Jun - 8 Jun
Comfort Suites St Charles - St Louis
Lobby lounge

Fairfield Inn & Suites Wentzville

Fairfield Inn & Suites Wentzville
3.0 star property
Wentzville
9.0 out of 10, Wonderful, (675 reviews)
"Property was nice, easy check-in, nice breakfast, room was clean."
United States
Doris
The price is €130
includes taxes & fees
7 Jun - 8 Jun
Fairfield Inn & Suites Wentzville
Indoor pool

Holiday Inn St. Louis West Six Flags by IHG

Holiday Inn St. Louis West Six Flags by IHG
3.0 star property
Eureka
9.0 out of 10, Wonderful, (1,000 reviews)
"Room was very clean and the breakfast was great!! "
United States
Myra
The price is €131
includes taxes & fees
22 Jun - 23 Jun
Holiday Inn St. Louis West Six Flags by IHG
Lobby

Days Inn by Wyndham St Peters/St Charles

Days Inn by Wyndham St Peters/St Charles
2.0 star property
St. Peters
6.2 out of 10, (1,003 reviews)
"Overall great experience, staff was friendly and very helpful. Made it a seamless experience from check in to check out."
United States
Chris
The price is €73
includes taxes & fees
15 Jun - 16 Jun
Days Inn by Wyndham St Peters/St Charles
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Stay near popular Defiance attractions

Photo by Pages of Travel
Open Photo by Pages of Travel

Chandler Hill Vineyards

3.9/5 (7 reviews)
This elegant Missouri winery showcases local and California wines from its hillside setting. Savour varietals on the expansive terrace while enjoying vineyard views and seasonal cuisine from their full-service kitchen.
See properties

Learn more about Defiance

Nestled along the Missouri River, this historic village offers scenic hiking trails and access to nearby wine country. Visit the Daniel Boone Home in neighbouring Defiance Township or enjoy tastings at the family-owned wineries dotting the surrounding countryside.

See all hotels in Defiance
A covered bridge at the Historic Daniel Boone Home Park in Defiance, Missouri

Top Defiance Hotel Reviews

Sleep Inn & Suites O'Fallon MO - Technology Drive

Sleep Inn & Suites O'Fallon MO - Technology Drive

2/10 Terrible
"Had a hard time checking in receptionist was not there to be almost 30 minutes waiting for this guy to attend me"
Elias 1-night trip
Posted 3 hours ago
Sleep Inn & Suites O'Fallon MO - Technology Drive

More cheap stays in Defiance

Motel 6 Maryland Heights, MO

Motel 6 Maryland Heights, MO

12330 Dorsett Rd Maryland Heights MO
The price is €60 per night from 31 May to 1 Jun
€60
31 May - 1 Jun
includes taxes & fees
6.2/10 (1,000 reviews)

Frequently asked questions

What's the best place to stay in Defiance?
Hollywood Casino & Hotel St. Louis, located 18.1 mi (29.2 km) from the heart of Defiance, is a top choice for your stay, based on our traveller data. Two other options for your visit to the area are Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham and The Wildwood Hotel. See all available top hotels, or vacation rentals in Defiance.
What are some of the best holiday rentals that Defiance has to offer?
🌟 Adorable Historic 🏠 in the ❤️ of St. Charles 🌟: This holiday home rental outside of Defiance offers a patio, a garden and air conditioning to help you feel perfectly comfortable in your new surroundings. Kitchen amenities include a dishwasher, a fridge and a stovetop. See all vacation rentals in Defiance.
If I need to cancel my hotel reservation in Defiance, will I receive a refund?
Yes! The majority of room reservations are fully refundable if you cancel before the accommodation's cancellation deadline, which often is within 24-48 hours of your check-in date. If you have a reservation that's non-refundable, you might be able to cancel it and receive a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Defiance.
What are some accommodation options with pools in Defiance?
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham: Offers an indoor pool, an outdoor pool and buffet. The Wildwood Hotel and Ameristar Casino Resort and Spa are two additional hotels with an on-site pool. View all hotels with pools in Defiance.
How is it staying in Defiance?
Visitors can enjoy all that Defiance has to offer, including the wineries and parks. Top sights in the area include St. Louis Union Station, Busch Stadium and Gateway Arch. In Defiance, there are 19 hotels and other accommodation options to choose from. Find out more about Defiance.
What should I do while I'm visiting Defiance?
Natural beauty is on display at August A. Busch Memorial Conservation Area, Missouri River and Matson Hill Park Trailhead. A couple of additional sights to add to your itinerary are Chandler Hill Vineyards and Sugar Creek Winery. Take a look at what more there is to see and do in Expedia's Defiance guide.
What's the weather like in Defiance?
The hottest months are usually July and August, with an average temperature of 24°C, while the coldest months are January and February, with an average of 3°C. Average annual precipitation for Defiance is 1228 mm.

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