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Defiance Hotels

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Tonight
14 Oct - 15 Oct
Tomorrow
15 Oct - 16 Oct
This weekend
17 Oct - 19 Oct
Next weekend
24 Oct - 26 Oct

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Top 10 trending Defiance hotels

Lobby sitting area
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
3.0 star property
8.2 out of 10, Very good, (1022)
"Clean room and staff was great "
The price is €85
includes taxes & fees
2 Nov - 3 Nov
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
Ballroom
The Wildwood Hotel
The Wildwood Hotel
3.5 star property
9.2 out of 10, Wonderful, (1591)
"We enjoyed our stay!"
The Wildwood Hotel
Front of property
Sonesta ES Suites St. Louis - Chesterfield
Sonesta ES Suites St. Louis - Chesterfield
3.0 star property
8.0 out of 10, Very good, (1006)
"This was a very nice place to stay. Centrally located, very clean and quiet with a great breakfast!"
The price is €87
includes taxes & fees
12 Nov - 13 Nov
Sonesta ES Suites St. Louis - Chesterfield
Front of property
Super 8 by Wyndham Eureka/Six Flags Nearby
Super 8 by Wyndham Eureka/Six Flags Nearby
2.0 star property
7.0 out of 10, Good, (1009)
"Quiet ,clean and safe "
The price is €60
includes taxes & fees
28 Oct - 29 Oct
Super 8 by Wyndham Eureka/Six Flags Nearby
Property amenity
Baymont by Wyndham Warrenton
Baymont by Wyndham Warrenton
2.5 star property
7.4 out of 10, Good, (1007)
"Very friendly staff. Nice place to stay"
The price is €85
includes taxes & fees
2 Nov - 3 Nov
Baymont by Wyndham Warrenton
Lobby
Best Western Plus St. Louis West-Westport
Best Western Plus St. Louis West-Westport
2.5 star property
8.0 out of 10, Very good, (1011)
"It was a very nice place"
The price is €88
includes taxes & fees
21 Oct - 22 Oct
Best Western Plus St. Louis West-Westport
Lobby
Sleep Inn & Suites O'Fallon MO - Technology Drive
Sleep Inn & Suites O'Fallon MO - Technology Drive
2.5 star property
8.8 out of 10, Excellent, (1013)
"Great hotel! "
The price is €89
includes taxes & fees
20 Oct - 21 Oct
Sleep Inn & Suites O'Fallon MO - Technology Drive
Front of property – evening/night
Hollywood Casino & Hotel St. Louis
Hollywood Casino & Hotel St. Louis
3.5 star property
8.4 out of 10, Very good, (2167)
"Always our favorite place to stay!"
The price is €101
includes taxes & fees
29 Oct - 30 Oct
Hollywood Casino & Hotel St. Louis
Lobby
Days Inn by Wyndham St Peters/St Charles
Days Inn by Wyndham St Peters/St Charles
2.0 star property
6.4 out of 10, (997)
"The carpet felt a little damp but aside from that the room was clean and comfortable. "
The price is €66
includes taxes & fees
21 Oct - 22 Oct
Days Inn by Wyndham St Peters/St Charles
Exterior
Holiday Inn Express & Suites Wentzville St Louis West by IHG
Holiday Inn Express & Suites Wentzville St Louis West by IHG
2.5 star property
9.4 out of 10, Exceptional, (805)
"The area around the hotel appeared to be safe and well kept. "
The price is €135
includes taxes & fees
1 Nov - 2 Nov
Holiday Inn Express & Suites Wentzville St Louis West by IHG
1 bedroom, Egyptian cotton sheets, premium bedding, pillow-top beds
Best Western Plus Washington Hotel
Best Western Plus Washington Hotel
2.5 star property
9.0 out of 10, Wonderful, (611)
"Clean and welcoming - great staff"
The price is €127
includes taxes & fees
16 Oct - 17 Oct
Best Western Plus Washington Hotel
Lobby
AC Hotel by Marriott St. Louis Chesterfield
AC Hotel by Marriott St. Louis Chesterfield
3.5 star property
9.2 out of 10, Wonderful, (210)
"Loved my stay here "
The price is €152
includes taxes & fees
30 Oct - 31 Oct
AC Hotel by Marriott St. Louis Chesterfield
Exterior
Hampton Inn St. Charles St. Peters
Hampton Inn St. Charles St. Peters
2.5 star property
8.0 out of 10, Very good, (1012)
"Excellent hotel. Excellent location, friendly staff, and delicious breakfast."
The price is €99
includes taxes & fees
3 Nov - 4 Nov
Hampton Inn St. Charles St. Peters
Terrace/patio
Elimwood Hotel, a Ramada by Wyndham
Elimwood Hotel, a Ramada by Wyndham
3.0 star property
7.4 out of 10, Good, (1009)
"Clean nice room, staff was all very friendly & helpful, exceptionally so. "
The price is €92
includes taxes & fees
23 Oct - 24 Oct
Elimwood Hotel, a Ramada by Wyndham
Lobby
Drury Plaza Hotel St. Louis St. Charles
Drury Plaza Hotel St. Louis St. Charles
3.0 star property
9.6 out of 10, Exceptional, (1010)
"Great staff and great amenities!"
The price is €110
includes taxes & fees
19 Oct - 20 Oct
Drury Plaza Hotel St. Louis St. Charles
Exterior
Holiday Inn Express St. Louis West - O'Fallon by IHG
Holiday Inn Express St. Louis West - O'Fallon by IHG
2.5 star property
8.6 out of 10, Excellent, (800)
"Clean, well maintained hotel. Friendly staff, great breakfast. Close to shopping and restaurants."
The price is €97
includes taxes & fees
26 Oct - 27 Oct
Holiday Inn Express St. Louis West - O'Fallon by IHG
Premium bedding, desk, iron/ironing board, free cots/infant beds
Super 8 by Wyndham St Charles
Super 8 by Wyndham St Charles
2.0 star property
8.0 out of 10, Very good, (1011)
"Clean room and comfortable bed I would stay again. "
The price is €75
includes taxes & fees
27 Oct - 28 Oct
Super 8 by Wyndham St Charles
Lobby
Super 8 by Wyndham Union
Super 8 by Wyndham Union
2.0 star property
8.2 out of 10, Very good, (621)
"Clean room great staff"
The price is €74
includes taxes & fees
12 Nov - 13 Nov
Super 8 by Wyndham Union
Desk, blackout curtains, iron/ironing board, free cots/infant beds
Wingate by Wyndham St. Louis/Fenton Route 66
Wingate by Wyndham St. Louis/Fenton Route 66
3.0 star property
8.0 out of 10, Very good, (1057)
"Room was comfortable and clean. Breakfast was continental with a pancake machine which was slow so I opted out. "
The price is €79
includes taxes & fees
11 Nov - 12 Nov
Wingate by Wyndham St. Louis/Fenton Route 66
Lobby
Comfort Inn & Suites St. Louis - O'Fallon
Comfort Inn & Suites St. Louis - O'Fallon
2.5 star property
7.6 out of 10, Good, (1005)
"And nice hotel at a nice price "
The price is €77
includes taxes & fees
28 Oct - 29 Oct
Comfort Inn & Suites St. Louis - O'Fallon
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Stay near popular Defiance attractions

Wetlands landscape with a bird blind and cloudy sky reflected in a lake at the August A. Busch Memorial Conservation Area in St. Charles County Missouri

August A. Busch Memorial Conservation Area

Explore the great outdoors at August A. Busch Memorial Conservation Area, a lovely green space in Defiance. While in this family-friendly area, you can savour the top-notch restaurants.
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Missouri wineries have some of the most superb wine we've ever tasted! We recommend sipping on some chambourcin while basking in the sunshine.
Photo by Pages of Travel
Open Photo by Pages of Travel

Chandler Hill Vineyards

You can enjoy a tasting or tour at Chandler Hill Vineyards during your travels to Defiance. While in this romantic area, you can savour the top-notch restaurants.
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Learn more about Defiance

Nestled along the Missouri River, this historic village offers scenic hiking trails and access to nearby wine country. Visit the Daniel Boone Home in neighbouring Defiance Township or enjoy tastings at the family-owned wineries dotting the surrounding countryside.

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Top Defiance Hotel Reviews

Drury Inn & Suites Southwest St. Louis

Drury Inn & Suites Southwest St. Louis

10/10 Excellent
"Breakfast was wonderful! We had a nice stay! Friendly staff, easy check in and out! Will definitely stay here again!"
Dawn 1-night trip
Posted 3 days ago
Drury Inn & Suites Southwest St. Louis

More cheap stays in Defiance

Relax Inn Saint Charles

Relax Inn Saint Charles

3800 Harry S Truman Blvd, St. Charles, MO
The price is €62 per night from 19 Oct to 20 Oct
€62
19 Oct - 20 Oct
includes taxes & fees
6.4/10 (1,005 reviews)

Frequently asked questions

What's the best place to stay in Defiance?
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham, located 17.9 mi (28.8 km) from the heart of Defiance, is a top choice for your stay, based on our traveller data. Two other options for your visit to the area are Hollywood Casino & Hotel St. Louis and La Quinta Inn & Suites by Wyndham St. Louis Westport. See all available top hotels, or vacation rentals in Defiance.
What are some of the best holiday rentals that Defiance has to offer?
St. Charles 1860's Gem - Sleeps 6!: This holiday home rental outside of Defiance is located on a river, and has a garden, a selection of books and air conditioning to put you at ease in your new surroundings. Kitchen amenities include a dishwasher, a fridge and a stovetop. See all vacation rentals in Defiance.
If I need to cancel my hotel reservation in Defiance, will I receive a refund?
Yes! The majority of room reservations are fully refundable if you cancel before the accommodation's cancellation deadline, which often is within 24-48 hours of your check-in date. If you have a reservation that's non-refundable, you might be able to cancel it and receive a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Defiance.
What are some accommodation options with pools in Defiance?
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham: Features an indoor pool, an outdoor pool and buffet. La Quinta Inn & Suites by Wyndham St. Louis Westport and Ameristar Casino Resort and Spa are two additional hotels with an on-site pool. View all hotels with pools in Defiance.
How is it staying in Defiance?
Visitors can enjoy all that Defiance has to offer, including the wineries and parks. Top sights in the area include St. Louis Union Station, Busch Stadium and Gateway Arch. In Defiance, there are 20 hotels and other accommodation options to choose from. Find out more about Defiance.
What should I do while I'm visiting Defiance?
Natural beauty is on display at August A. Busch Memorial Conservation Area, Missouri River and Matson Hill Park Trailhead. A couple of additional sights to add to your itinerary are Yellow Farmhouse Winery and Chandler Hill Vineyards. Take a look at what more there is to see and do in Expedia's Defiance guide.
What's the weather like in Defiance?
The hottest months are usually July and August, with an average temperature of 24°C, while the coldest months are January and February, with an average of 3°C. Average annual precipitation for Defiance is 1228 mm.

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