
Defiance Hotels
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Our top choices for Defiance hotels

WoodSpring Suites St Peters-OFallon
WoodSpring Suites St Peters-OFallonSt. Peters
9.0 out of 10, Wonderful, (45 reviews)
The price is €89
includes taxes & fees
2 Mar - 3 Mar

Baymont by Wyndham Warrenton
Baymont by Wyndham WarrentonWarrenton
7.4 out of 10, Good, (1,000 reviews)
The price is €70
includes taxes & fees
1 Mar - 2 Mar

Comfort Inn & Suites St. Louis - O'Fallon
Comfort Inn & Suites St. Louis - O'FallonO'Fallon
7.6 out of 10, Good, (1,000 reviews)
The price is €83
includes taxes & fees
29 Mar - 30 Mar

Quality Inn Foristell
Quality Inn ForistellForistell
8.2 out of 10, Very good, (944 reviews)
The price is €71
includes taxes & fees
8 Mar - 9 Mar

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
Heritage Inn & Suites St. Louis/Fenton, Trademark by WyndhamFenton
8.0 out of 10, Very good, (1,108 reviews)
The price is €87
includes taxes & fees
9 Mar - 10 Mar

Comfort Suites St Charles - St Louis
Comfort Suites St Charles - St LouisSt. Charles
8.4 out of 10, Very good, (1,001 reviews)
The price is €89
includes taxes & fees
22 Mar - 23 Mar

Holiday Inn Express & Suites Wentzville St Louis West by IHG
Holiday Inn Express & Suites Wentzville St Louis West by IHGWentzville
9.4 out of 10, Exceptional, (872 reviews)
The price is €136
includes taxes & fees
29 Mar - 30 Mar

Drury Inn & Suites St. Louis St. Peters
Drury Inn & Suites St. Louis St. PetersSt. Peters
9.4 out of 10, Exceptional, (1,002 reviews)
The price is €107
includes taxes & fees
5 Mar - 6 Mar

Super 8 by Wyndham Warrenton
Super 8 by Wyndham WarrentonWarrenton
7.4 out of 10, Good, (629 reviews)
The price is €59
includes taxes & fees
10 Mar - 11 Mar

Best Western Plus Washington Hotel
Best Western Plus Washington HotelWashington
9.2 out of 10, Wonderful, (662 reviews)
The price is €124
includes taxes & fees
1 Mar - 2 Mar

Relax Inn Saint Charles
Relax Inn Saint CharlesSt. Charles
6.8 out of 10, (1,005 reviews)
The price is €61
includes taxes & fees
3 Mar - 4 Mar

Fairfield Inn & Suites Wentzville
Fairfield Inn & Suites WentzvilleWentzville
9.0 out of 10, Wonderful, (658 reviews)
The price is €124
includes taxes & fees
8 Mar - 9 Mar

Best Western Plus Fenton
Best Western Plus FentonFenton
9.2 out of 10, Wonderful, (215 reviews)
The price is €89
includes taxes & fees
1 Mar - 2 Mar

Sleep Inn & Suites O'Fallon MO - Technology Drive
Sleep Inn & Suites O'Fallon MO - Technology DriveO'Fallon
9.0 out of 10, Wonderful, (1,002 reviews)
The price is €79
includes taxes & fees
15 Mar - 16 Mar

Courtyard by Marriott St. Louis St. Peters
Courtyard by Marriott St. Louis St. PetersSt. Peters
9.0 out of 10, Wonderful, (678 reviews)
The price is €114
includes taxes & fees
8 Mar - 9 Mar

Holiday Inn Express Warrenton by IHG
Holiday Inn Express Warrenton by IHGWarrenton
9.0 out of 10, Wonderful, (523 reviews)
The price is €139
includes taxes & fees
1 Mar - 2 Mar

Drury Inn & Suites Southwest St. Louis
Drury Inn & Suites Southwest St. LouisValley Park
9.6 out of 10, Exceptional, (1,000 reviews)
The price is €114
includes taxes & fees
4 Mar - 5 Mar

Super 8 by Wyndham Union
Super 8 by Wyndham UnionUnion
8.2 out of 10, Very good, (638 reviews)
The price is €74
includes taxes & fees
8 Mar - 9 Mar

Hampton Inn St. Louis Wentzville
Hampton Inn St. Louis WentzvilleWentzville
9.0 out of 10, Wonderful, (664 reviews)
The price is €116
includes taxes & fees
8 Mar - 9 Mar
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Stay near popular Defiance attractions
Learn more about Defiance
Nestled along the Missouri River, this historic village offers scenic hiking trails and access to nearby wine country. Visit the Daniel Boone Home in neighbouring Defiance Township or enjoy tastings at the family-owned wineries dotting the surrounding countryside.

Top Defiance Hotel Reviews

La Quinta Inn & Suites by Wyndham St. Louis Westport
10/10 Excellent
More cheap stays in Defiance

Relax Inn Saint Charles
3800 Harry S Truman Blvd St. Charles MO
The price is €61 per night from 3 Mar to 4 Mar
€61
3 Mar - 4 Mar
includes taxes & fees
6.8/10 (1,005 reviews)
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- Centene Community Ice Center
- Chandler Hill Vineyards
- Visit Crestwood
- Defiance Holidays
- Fenton Holidays
- Grant's Farm
- Visit Harvester
- Kirkwood Park
- Labadie Holidays
- Laumeier Sculpture Park
- Magic House - St. Louis Children's Museum
- Payne-Gentry Historical House
- Robertsville State Park
- Route 66 State Park
- Saint Louis Galleria Mall
- Sky Zone Indoor Trampoline Park - St. Louis
- Spooner's Frozen Custard
- St. Jordan Creek Winery
- St. Louis Car Museum
- Visit Edmundson
- St. Peters Holidays
- Sunset Hills Holidays
- Wentzville Holidays
- Woodbine Center Shopping Center
- Airport Van Rental Rental Cars in Liguori
- Car hire near Fast Lane Classic Cars
- Car hire Hamburg
- Car hire St. Peters
- Car hire Town and Country
- Car hire near Westport Plaza
- Enterprise Rental Cars in Des Peres
- Hertz Rental Cars in Lambert-St. Louis Intl.
- Localiza Rental Cars in House Springs
- National Car Rental Rental Cars in Town and Country












































































