St. Charles Hotel Guide - Luxury Hotels in St. Charles, St. Louis

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Our top choices for St. Charles luxury hotels

Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa
4.5 star property
St. Charles
8.4 out of 10, Very good, (1001)
"Clean room, wonderful helpful pleasant staff, amenities, everything was great love staying here!"
United States
Robyn
The price is €192
includes taxes & fees
11 Jan - 12 Jan 2026
Ameristar Casino Resort and Spa

River City Casino & Hotel

River City Casino & Hotel
4.0 star property
St. Louis
9.0 out of 10, Wonderful, (1455)
"Everything was absolutely wonderfull"
United States
Suada
The price is €110
includes taxes & fees
1 Jan - 2 Jan 2026
River City Casino & Hotel

Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch
4.0 star property
Downtown St. Louis
8.4 out of 10, Very good, (4031)
"Staff was supper nice and it all went so smooth."
United States
Brayden
The price is €129
includes taxes & fees
1 Jan - 2 Jan 2026
Hyatt Regency St. Louis at The Arch

White House at Grand Central

White House at Grand Central
4.0 star property
Grand Center
8.4 out of 10, Very good, (126)
"Very clean and very friendly people "
United States
Mary
The price is €127
includes taxes & fees
6 Jan - 7 Jan 2026
White House at Grand Central

Moonrise Hotel

Moonrise Hotel
4.0 star property
Delmar Loop
9.0 out of 10, Wonderful, (1919)
"Great place"
United States
Edward
The price is €126
includes taxes & fees
14 Jan - 15 Jan 2026
Moonrise Hotel

Hilton Pennywell St. Louis at the Arch

Hilton Pennywell St. Louis at the Arch
4.0 star property
Downtown St. Louis
8.8 out of 10, Excellent, (1020)
"Staff were real nice. Accommodating. "
United States
Tim
The price is €107
includes taxes & fees
15 Jan - 16 Jan 2026
Hilton Pennywell St. Louis at the Arch

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
4.0 star property
Downtown St. Louis
8.8 out of 10, Excellent, (1178)
"Great staff and location"
United States
Robin or David
The price is €98
includes taxes & fees
25 Jan - 26 Jan 2026
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

The Cheshire

The Cheshire
4.0 star property
Richmond Heights
8.6 out of 10, Excellent, (1002)
"The place is beautiful, the room is very cozy and comfortable, the hotel well located with good breakfast. "
United States
Maria
The price is €119
includes taxes & fees
18 Jan - 19 Jan 2026
The Cheshire

Embassy Suites by Hilton St. Louis Downtown

Embassy Suites by Hilton St. Louis Downtown
4.0 star property
Downtown St. Louis
8.8 out of 10, Excellent, (1260)
"Very cool hotel, rooms were clean and nice design, the food at the bar/restaurant was fantastic!!!"
United States
Cullin
The price is €115
includes taxes & fees
15 Jan - 16 Jan 2026
Embassy Suites by Hilton St. Louis Downtown

Renaissance St. Louis Airport Hotel

Renaissance St. Louis Airport Hotel
4.0 star property
Berkeley
8.4 out of 10, Very good, (1064)
"I loved the service, room cleanliness, club lounge offered a nice variety of food and treats. The property is noticeably old but well maintained. "
United States
Ingrid I
The price is €121
includes taxes & fees
16 Jan - 17 Jan 2026
Renaissance St. Louis Airport Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top St. Charles Hotel Reviews

Frequently asked questions

Are you looking for a luxury hotel for your stay in St. Charles?
During your visit, you might want to enjoy the casinos and shopping which St. Charles is known for.
What's the best luxury hotel in St. Charles?
Ameristar Casino Resort and Spa is a luxury hotel with 6 restaurants and 2 bars, and it's a popular choice for Expedia travellers looking for an elegant place to stay.
When can I expect good weather in St. Charles?
Planning for the weather is an important factor for making your trip to St. Charles a success, especially when you're splurging. The hottest months are usually July and August, with an average temperature of 24°C, while the coldest months are January and February, with an average of 3°C. Average annual precipitation for St. Charles is 1172 mm.
What's there to see and do in St. Charles?
When you're in St. Charles, enjoy exploring the sights and attractions here including Historic Main Street, First Missouri State Capitol Historic Site and Katy Trail. If you have a little extra time during your trip, you might want to make a stop at Lewis & Clark Boathouse and Nature Center and St Charles Convention Center.

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