St. Louis Hotel Guide - Hotels with Spa in St. Louis, Missouri

Top St. Louis (and vicinity) attractions for a relaxing vacation

For travellers seeking an indulgent escape in the greater St. Louis area, the vibrant neighbourhood of Clayton is a splendid choice. This upscale district is home to an array of luxurious spa hotels where guests can unwind after exploring the city's highlights. Just a short drive away, the Missouri Botanical Garden offers a serene retreat with its stunning landscapes and tranquil Japanese Garden, perfect for a leisurely stroll. Art enthusiasts will appreciate a visit to the Saint Louis Art Museum, where world-class exhibits await amidst the picturesque setting of Forest Park, one of the largest urban parks in the United States. Families can enjoy a day of fun at the Saint Louis Zoo, known for its exceptional animal exhibits and free admission, providing a delightful experience for all ages. After a day of adventure, retreat to your spa hotel in Clayton, where attentive service and pampering treatments await, ensuring you feel rejuvenated and cared for. The combination of luxury accommodation and engaging local attractions makes Clayton an ideal base for a memorable family getaway.

Find the best hotels & resorts with spas in St. Louis (and vicinity)

For those seeking a rejuvenating escape in St. Louis, these hotels offer exceptional spa amenities that promise relaxation and pampering during your stay.

The Royal Sonesta Chase Park Plaza St. Louis

• Why it's great for tailored spa getaway: The Royal Sonesta Chase Park Plaza St. Louis is a sophisticated choice for travellers seeking a relaxing getaway, with a wonderful review rating of 9.0. This hotel features spa treatment rooms, offering guests the chance to unwind with various treatments tailored to their needs.
• Other amenities: Beyond spa services, guests can enjoy a health club, luxurious designer toiletries, and a poolside bar for refreshing drinks. This hotel also provides valet parking, a concierge service, and the option of self-parking. With nearby golf options and a beautiful balcony in select rooms, it’s an ideal choice for those wanting a mix of relaxation and leisure.
• Neighborhood: Central West End
• Nearby attractions: Forest Park - 0 km

21C Museum Hotel St Louis

• Why it's great for tailored spa getaway: At 21C Museum Hotel St Louis, guests can enjoy a unique blend of art and relaxation, complemented by an excellent review rating of 9.0. The onsite spa features massage treatments and a steam room, ensuring guests can indulge in self-care after exploring the vibrant city.
• Other amenities: The hotel also offers an indoor pool, accessible fitness centre, and luxurious deep soaking bathtubs in select rooms. Guests can take advantage of valet parking and daily housekeeping, while the chic decor and contemporary art installations throughout the hotel create a vibrant atmosphere that enhances the overall experience.
• Neighborhood: Downtown West
• Nearby attractions: City Museum - 0.5 km, Enterprise Center - 0.7 km, St. Louis Union Station - 0.7 km

DoubleTree by Hilton Hotel St. Louis - Chesterfield

• Why it's great for tailored spa getaway: The DoubleTree by Hilton Hotel St. Louis - Chesterfield is a great option for relaxation seekers, a solid review rating of 8.6. The hotel features treatment rooms where guests can indulge in therapeutic treatments for a refreshing experience.
• Other amenities: The hotel also offers an indoor pool, hot tub, and access to a health club, ensuring guests can maintain their wellness routines. Additional features include onsite shopping, billiards, and air conditioning for utmost comfort. Guests can also enjoy daily housekeeping, premium bedding, and the convenience of early check-in or late check-out.
• Nearby attractions: Chesterfield Arts - 1.7 km, The J - Chesterfield Gym & Fitness Center - 2.4 km

DoubleTree by Hilton Hotel St. Louis - Chesterfield

• Why it's great for tailored spa getaway: The DoubleTree by Hilton Hotel St. Louis - Chesterfield offers spa treatments that promise relaxation, complemented by a solid review rating of 8.6. With dedicated treatment rooms, guests can enjoy a range of services designed to rejuvenate and refresh during their stay in this welcoming environment.
• Other amenities: The hotel features an indoor pool, hot tub, and tennis courts for active guests. A fitness centre and concierge services further enhance the experience, while the on-site restaurant and poolside bar provide delightful dining options. Additional conveniences include free toiletries, accessible parking, and grocery facilities nearby.
• Nearby attractions: Chesterfield Arts - 1.7 km, The J - Chesterfield Gym & Fitness Center - 2.4 km

Ameristar Casino Resort and Spa

• Why it's great for tailored spa getaway: Ameristar Casino Resort and Spa is a fantastic destination for spa lovers, featuring a review rating of 8.4. The hotel boasts an onsite spa offering an array of treatments, including hydrotherapy and aromatherapy, ensuring guests can indulge in relaxation and pampering throughout their stay.
• Other amenities: Guests can enjoy a variety of leisure options including pools and hot tubs, as well as 24-hour fitness facilities. The hotel also offers luxurious suites, premium bedding, and a casino for entertainment. With concierge services, snack bars, and nearby golf options, this resort caters to those looking for both relaxation and excitement.
• Nearby attractions: Historic Main Street - 1.1 km, Ameristar Casino St. Charles - 0 km, Lewis & Clark Boathouse and Nature Center - 1.1 km