Clayton Hotel Guide - Hotels with Spa in Clayton, St. Louis

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Check availability on Clayton Hotels with Spa

Top Clayton Hotels with Spa

Our top choices for Clayton hotels with a spa

21C Museum Hotel St Louis
Exterior

21C Museum Hotel St Louis

4.5 star property
9.0 out of 10, Wonderful, (1316)
"Amazing hotel!"
The price is €157
includes taxes & fees
14 Sept - 15 Sept
21C Museum Hotel St Louis
Ameristar Casino Resort and Spa
6 restaurants, breakfast served

Ameristar Casino Resort and Spa

4.5 star property
8.4 out of 10, Very good, (1001)
"Loved my stay here will be back "
The price is €184
includes taxes & fees
24 Aug - 25 Aug
Ameristar Casino Resort and Spa
Four Seasons Hotel St Louis
Rooftop bar

Four Seasons Hotel St Louis

5.0 star property
9.4 out of 10, Exceptional, (1000)
"We’ve stayed at this hotel several times and keep coming back. Great hotel staff and property. "
The price is €426
includes taxes & fees
26 Aug - 27 Aug
Four Seasons Hotel St Louis
The Ritz-Carlton, St. Louis
Meeting facility

The Ritz-Carlton, St. Louis

5.0 star property
9.2 out of 10, Wonderful, (544)
"Great place"
The price is €519
includes taxes & fees
21 Sept - 22 Sept
The Ritz-Carlton, St. Louis
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Clayton Hotel Reviews

Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

10/10 Excellent
"Clean rooms excellent staff wonderful on site Breakfast"
Karen 1-night trip
Posted 1 day ago
Clayton Plaza Hotel & Extended Stay

Frequently asked questions

Looking for a spa hotel in Clayton?
Book one of our lush spa hotels and pamper yourself from the moment you arrive. Travellers highly recommend the restaurants in Clayton. Make sure you pay a visit to the museums during your stay. Hotels with spas are the perfect way to break away from your daily routine and add a layer of luxury to your stay.
What's there to see and do in Clayton?
Enjoy all that Clayton has to offer when you visit Chapel of St. Timothy And St. Titus, Concordia Seminary, St. Louis Union Station and Busch Stadium. If you have some spare time during your trip, you might want to check out Gateway Arch and Saint Louis Galleria Mall.
What is a Clayton spa hotel?
Spa hotels in Clayton provide lodging and have an on-site spa offering services including facials and body treatments. Some also offer in-room treatments. Spa hotels are great for rest, rejuvenation and relaxation.