Clayton Hotel Guide - Hotels with Spa in Clayton, St. Louis
Change your mind
Book hotels with free cancellation
Be picky
Search almost a million properties worldwide
Check availability on Clayton Hotels with Spa
Top Clayton Hotels with Spa
Our top choices for Clayton hotels with a spa

21C Museum Hotel St Louis
21C Museum Hotel St Louis
9.0 out of 10, Wonderful, (1316)
The price is €157
includes taxes & fees
14 Sept - 15 Sept

Ameristar Casino Resort and Spa
Ameristar Casino Resort and Spa
8.4 out of 10, Very good, (1001)
The price is €184
includes taxes & fees
24 Aug - 25 Aug

Four Seasons Hotel St Louis
Four Seasons Hotel St Louis
9.4 out of 10, Exceptional, (1000)
The price is €426
includes taxes & fees
26 Aug - 27 Aug

The Ritz-Carlton, St. Louis
The Ritz-Carlton, St. Louis
9.2 out of 10, Wonderful, (544)
The price is €519
includes taxes & fees
21 Sept - 22 Sept
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top Clayton Hotel Reviews

Clayton Plaza Hotel & Extended Stay
10/10 Excellent
Explore a world of travel with Expedia
Explore a world of travel with Expedia
More accommodation types in Clayton
More top Clayton Hotels
- Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
- Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
- Moonrise Hotel
- 21C Museum Hotel St Louis
- Pear Tree Inn St. Louis Near Union Station
- River City Casino & Hotel
- Drury Inn & Suites St. Louis Union Station
- Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West
- Hilton St. Louis at the Ballpark
- Pear Tree Inn St. Louis Convention Center
- Live by Loews - St.Louis
- Wingate by Wyndham St. Louis/Fenton Route 66
- Forest Park Hotel by MDR
- Embassy Suites by Hilton St. Louis Downtown
- St. Louis Union Station Hotel, Curio Collection by Hilton
- Drury Inn & Suites St. Louis Airport
Expedia's Latest Trends
Hotels
- 2 Heated Communal Pools and a splash pool with Sea Views
- Hotels near Orio Al Serio
- Villas Europe
- Hotels in Madeira Island
- Hotels with Spa in Manchester City Centre
- Laguna Park 2
- Bull Eugenia Victoria & Spa
- Hotel Montemar Benidorm
- The Prime Energize Hotel & Spa
- Apartment with a swimming pool and a beautiful view of the sea, city & mountain.
- Hotels with Connecting Rooms in Lake Garda
- Hotels with Pool in County Kilkenny
- Hotel Sol e Mar - Adults Only
- Hotels near Pisa Central Station
Flights
Activities