The illuminated Gateway Arch at night with a city skyline in the background.

Clayton Hotel Guide - Boutique Hotels in Clayton, St. Louis

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Check availability on Clayton Boutique Hotels

Our top choices for Clayton boutique hotels

1. Seven Gables, St. Louis West, a Tribute Portfolio Hotel

Seven Gables, St. Louis West, a Tribute Portfolio Hotel
3.5 star property
Clayton
8.4 out of 10, Very good, (601 reviews)
"I always stay at the Seven Gables Inn while visiting St. Louis - fantastic, walkable neighborhood, for central STL, including vintage shopping & dining options. The boutique hotel is very ‘Old St. Louis’ with extremely modern, comfortable, quiet and safe rooms."
United States
Jennifer
The price is €158
includes taxes & fees
27 Sept - 28 Sept
Seven Gables, St. Louis West, a Tribute Portfolio Hotel

2. The Cheshire

The Cheshire
4.0 star property
Richmond Heights
8.8 out of 10, Excellent, (1,007 reviews)
"Fantastic hotel, clean and nice rooms, great breakfast and location"
United States
Matthew
The price is €147
includes taxes & fees
20 Sept - 21 Sept
The Cheshire

3. Moonrise Hotel

Moonrise Hotel
4.0 star property
Delmar Loop
9.0 out of 10, Wonderful, (2,019 reviews)
"Great location, clean rooms, and friendly staff. We will definitely stay again."
United States
Nicole
The price is €135
includes taxes & fees
7 Oct - 8 Oct
Moonrise Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Clayton Hotel Reviews

Frequently asked questions

What's the best boutique hotel in Clayton?
Seven Gables, St. Louis West, a Tribute Portfolio Hotel is a favourite hotel with our travellers looking for stylish accommodation, and features 32 guestrooms, a garden and free WiFi.
What's there to see and do in Clayton?
The shopping, restaurants and sporting events are just some of the things to enjoy while you're in the area. Major sights and activities around Clayton include St. Louis Zoo, St. Louis Union Station and Gateway Arch. You might also want to consider exploring Chapel of St. Timothy And St. Titus, Concordia Seminary, Saint Louis Galleria Mall and St. Louis Art Museum while you're here.
What's the best way to get to my boutique hotel in Clayton?
You have a few options for getting to Clayton. The closest major airport is Lambert-St. Louis International Airport (STL), which is located 7.3 mi (11.7 km) away, but St. Louis, MO (SUS-Spirit of St. Louis) may also be an option. Make your way to Clayton Station to catch the metro.

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