
Defiance Holidays
Photo by Michael True
- Plan, book, travel with confidence
Better together
Save up to €185 when you book a flight and hotel together*
Find the right fit
With over 300,000 hotels worldwide, it's easy to create a perfect package
Rest easy
Plan, book, and manage your trip all in one place
Top hotels in Defiance

Hollywood Casino & Hotel St. Louis
777 Casino Center Drive, Maryland Heights, MO
Fully refundableReserve now, pay when you stay
The price is €123 per night from 11 Aug to 12 Aug
€123
11 Aug - 12 Aug
includes taxes & fees
8.2/10 Very Good! (2,040 reviews)
"Very nice!"
Reviewed on 6 Aug 2025

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
1088 South Highway Drive, Fenton, MO
Fully refundableReserve now, pay when you stay
The price is €89 per night from 31 Aug to 1 Sept
€89
31 Aug - 1 Sept
includes taxes & fees
8.2/10 Very Good! (1,000 reviews)
"Very clean and friendly staff. Breakfast was excellent"
Reviewed on 5 Aug 2025

Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West
13639 Riverport Dr, Maryland Heights, MO
Fully refundableReserve now, pay when you stay
The price is €74 per night from 8 Sept to 9 Sept
€74
8 Sept - 9 Sept
includes taxes & fees
7.2/10 Good! (1,010 reviews)
"Great Service and Rooms are Excellent"
Reviewed on 7 Aug 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Popular places to visit

Gateway Arch
Enjoy 360-degree views and learn about the history of St. Louis at this world-famous landmark.

St. Louis Zoo
In the middle of St. Louis, meet the exotic and endangered animals that live in meticulously recreated ecosystems from all over the world.
Enterprise Center
Catch an event at Enterprise Center during your trip to St. Louis. Experience the area's acclaimed art galleries or attend a baseball game.
What to do in Defiance

St. Louis Arch Walking Tour and Entrance Ticket
€43
per adult
100% of travellers recommend

St Louis Ghost Tours: Sinister Sins & Shadows Ghost Tour
€21
per adult

Best of St. Louis Small Group Tour w/ Arch & River Cruise
€145
per adult
84% of travellers recommend
Frequently asked questions
More trip options
Expedia's Latest Trends
Hotels
- Hotels near Frankfurt Intl.
- Eden Andalou Aquapark & Spa
- Hotels near Bramall Lane
- Cheap Hotels in Letterkenny
- Hotels with Spa in Wexford
- Hotels near Caragh Lake
- Caravan Parks Bettystown
- Hotels in Leeds City Center
- Hotels in Salou
- Melia Punta Cana Beach Wellness Inclusive - Adults only
- The Lawrence
- Teach Teolai
- Hotels in Pitlochry
- Crowne Plaza HY36 Midtown Manhattan by IHG
- Moment Hotels
- Hotels near Southampton Cruise Terminal
Flights
General
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.