Defiance Holidays

Photo by Michael True

  • Plan, book, travel with confidence

    • payments icon

    Better together

    Save up to €185 when you book a flight and hotel together*
    lob hotels icon

    Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package
    lob packages icon

    Rest easy

    Plan, book, and manage your trip all in one place

Top hotels in Defiance

Hollywood Casino & Hotel St. Louis

Hollywood Casino & Hotel St. Louis

3.5 out of 5
777 Casino Center Drive, Maryland Heights, MO
Fully refundableReserve now, pay when you stay
The price is €123 per night from 11 Aug to 12 Aug
€123
11 Aug - 12 Aug
includes taxes & fees
8.2/10 Very Good! (2,040 reviews)
"Very nice!"

Reviewed on 6 Aug 2025

Hollywood Casino & Hotel St. Louis
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

3 out of 5
1088 South Highway Drive, Fenton, MO
Fully refundableReserve now, pay when you stay
The price is €89 per night from 31 Aug to 1 Sept
€89
31 Aug - 1 Sept
includes taxes & fees
8.2/10 Very Good! (1,000 reviews)
"Very clean and friendly staff. Breakfast was excellent"

Reviewed on 5 Aug 2025

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West

Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West

3 out of 5
13639 Riverport Dr, Maryland Heights, MO
Fully refundableReserve now, pay when you stay
The price is €74 per night from 8 Sept to 9 Sept
€74
8 Sept - 9 Sept
includes taxes & fees
7.2/10 Good! (1,010 reviews)
"Great Service and Rooms are Excellent"

Reviewed on 7 Aug 2025

Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West
See all 830 properties in Defiance
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Popular places to visit

Gateway Arch which includes central business district, modern architecture and a city

Gateway Arch

Enjoy 360-degree views and learn about the history of St. Louis at this world-famous landmark.

Gateway Arch
St. Louis Zoo

St. Louis Zoo

In the middle of St. Louis, meet the exotic and endangered animals that live in meticulously recreated ecosystems from all over the world.

St. Louis Zoo

Enterprise Center

Catch an event at Enterprise Center during your trip to St. Louis. Experience the area's acclaimed art galleries or attend a baseball game.

Enterprise Center

What to do in Defiance

St. Louis Arch Walking Tour and Entrance Ticket

St. Louis Arch Walking Tour and Entrance Ticket

€43
per adult
100% of travellers recommend
St. Louis Arch Walking Tour and Entrance Ticket
St. Louis: Gateway Ghouls and Hauntings Walking Tour

St Louis Ghost Tours: Sinister Sins & Shadows Ghost Tour

€21
per adult
St Louis Ghost Tours: Sinister Sins & Shadows Ghost Tour
Best of St. Louis Small Group Tour w/ Arch & River Cruise

Best of St. Louis Small Group Tour w/ Arch & River Cruise

€145
per adult
84% of travellers recommend
Best of St. Louis Small Group Tour w/ Arch & River Cruise
See all activities in Defiance

Frequently asked questions

How much does a Defiance holiday package cost?
You can grab a holiday package to this popular destination on Expedia. However, how much your holiday to Defiance costs will depend on factors like the season, hotel choice and length of stay.
What are the cheapest months to go to Defiance?
Plan your getaway for the shoulder or low season and you're likely to find cheap Defiance holiday packages. Remember that public holidays and major local events can have an impact on prices, so do a little research before booking.
How many days is enough for Defiance?
With a well-planned schedule, you can easily tick off the main Defiance attractions in a few days. But if you want to explore off the beaten track or go on day trips, consider booking your Defiance holiday for longer.
How to find the best Defiance package deals?
Use Expedia's filters to find some terrific Defiance package deals. When you begin your search, simply set your maximum budget and then sort the results by "Price: low to high." If you're looking to save, plan your trip for midweek, or search for Defiance package deals in the off-season. Switch up your travel dates and you may land even bigger discounts. As a rule of thumb, it's typically best to book your holiday package well in advance.
Is it cheaper to book a Defiance holiday as a package?
Expedia holiday packages are designed to help you keep more cash in your pocket. Bundle your hotel, car rental and flight into one great-value price and you could save hundreds of dollars. You'll usually land a better deal than booking each component separately. And you'll still enjoy the flexibility to create a customised Defiance holiday by choosing your favourite airline, accommodation type and car class.
When to book a holiday package to Defiance?
If you have your Defiance holiday dates locked in, book as soon as you can to snap up some awesome deals. With Expedia, you can generally reserve some flights up to one year ahead of time. Prefer spontaneous getaways? Our last-minute deals are perfect for quick escapes.
How to plan a trip to Defiance?

  1. Choose your dates: The things you'd like to do in Defiance and your favourite season can help you decide when to get away.
  2. Plan your budget wisely: In addition to the cost of your hotel, you'll need to factor in other expenses too. These include transportation, food and flights. Also, set aside some extra funds for unexpected costs that could crop up during your trip to Defiance.
  3. Decide how long to go away for: Now that you know more about Defiance, you can figure out the perfect length of your holiday. Create a draft itinerary and allocate enough time for all the things you want to do.
  4. Combine your airfare and accommodation: Once you've nailed down your travel dates and duration, lock in the right Defiance holiday package for you.

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.