Defiance Holidays
- Plan, book, travel with confidence
- Better togetherSave up to €900 when you book a flight and hotel together*
- Find the right fitWith over 300,000 hotels worldwide, it's easy to create a perfect package
- Rest easyPlan, book, and manage your trip all in one place
Top hotels in Defiance
Hollywood Casino & Hotel St. Louis
777 Casino Center Drive Maryland Heights MO
Fully refundableReserve now, pay when you stay
The price is €110 per night from 1 Jun to 2 Jun
€110
1 Jun - 2 Jun
includes taxes & fees
8.4/10 Very Good! (2,234 reviews)
"Stayed here for our wedding can’t say enough good things and can’t wait to come back!"
Reviewed on 20 May 2026
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
1088 South Highway Drive Fenton MO
Fully refundableReserve now, pay when you stay
The price is €99 per night from 26 May to 27 May
€99
26 May - 27 May
includes taxes & fees
8/10 Very Good! (1,289 reviews)
"Very clean"
Reviewed on 21 May 2026
The Wildwood Hotel
2801 Fountain Pl Wildwood MO
Fully refundableReserve now, pay when you stay
The price is €88 per night from 25 May to 26 May
€88
25 May - 26 May
includes taxes & fees
9.2/10 Wonderful! (1,645 reviews)
"Yup"
Reviewed on 20 May 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Popular places to visit
Gateway Arch
5/5(16 reviews)
Enjoy 360-degree views and learn about the history of St. Louis at this world-famous landmark.
St. Louis Zoo
In the middle of St. Louis, meet the exotic and endangered animals that live in meticulously recreated ecosystems from all over the world.
Enterprise Center
Catch an event at Enterprise Center during your trip to St. Louis. Experience the area's fascinating museums or attend a baseball game.
What to do in Defiance
St. Louis Narrated Trolley Tour
€26
per adult
90% of travellers recommend
St. Louis Ghost Tour: Sinister Sins & Shadows
€20
per adult
St. Louis Premium Small Group Tour With Arch & River Cruise
€144
per adult
84% of travellers recommend
Explore a world of travel with Expedia
- 4 Star Hotels in Innsbrook
- Aspenhoff Hotels
- Drury Inn & Suites Hotels in Augusta
- Augusta Hotels
- Cheap Hotels in Bridgeton
- Cabin Rentals in Chesterfield
- Luxury Hotels in Chesterfield
- Chesterfield Hotels
- Creve Coeur Hotels
- Defiance Hotels
- Des Peres Hotels
- Earth City Hotels
- Hotels with Bar in Eureka
- Eureka Hotels
- Fenton Hotels
- Frontenac Hotels
- Best Western Hotels in Harvester
- Innsbrook Hotels
- Lake St Louis Hotels
- Hotels near Lambert-St. Louis Intl.
- Hotels near Magic House - St. Louis Children's Museum
- Casino Hotels in Maryland Heights
- Maryland Heights Hotels
- Hotels near National Equestrian Center
- O'fallon Hotels
- Pacific Hotels
- Parkdale Hotels
- St. Ann Hotels
- Cheap Hotels in St. Charles
- Luxury Hotels in St. Charles
- St. Charles Hotels
- Cottages in St. Peters
- Casino Hotels in St. Peters
- St. Peters Hotels
- Hotels with WiFi in Sunset Hills
- Union Hotels
- Lgbt-Friendly Hotels in Washington
- Washington Hotels
- Hotels near Westport Plaza
- Westwood Hotels
- Wright City Hotels
- Flights to Ballwin
- Flights to O'Fallon
- Flights to Pacific
- Flights to Wentzville
- Flights from Lambert-St. Louis Intl.
- Flights from Nashville (BNA) to St. Louis (STL)
- Flights from Burlington (BTV) to St. Louis (STL)
- Flights from Detroit (DTW) to St. Louis (STL)
- Flights from Dublin (DUB) to St. Louis (SUS)
- Flights from Newark Liberty Intl. Airport (EWR) to St. Louis (STL)
- Flights from Londonderry (LDY) to St. Louis (STL)
- Flights from Naypyidaw (NYT) to St. Louis (STL)
- Flights from Cork (ORK) to St. Louis (STL)
- Flights from Seattle (SEA) to St. Louis (STL)
- Flights from Knoxville (TYS) to St. Louis (STL)
- Flights from Surat Thani (URT) to St. Louis (STL)
- Flights from Toronto (YYZ) to St. Louis (STL)
- Calvary Cemetery
- Centene Community Ice Center
- Chandler Hill Vineyards
- Visit Crestwood
- Fenton Holidays
- Grant's Farm
- Visit Harvester
- Kirkwood Park
- Labadie Holidays
- Laumeier Sculpture Park
- Magic House - St. Louis Children's Museum
- Mastodon State Historic Site
- Missouri Botanical Gardens and Arboretum
- Payne-Gentry Historical House
- River City Casino
- Robertsville State Park
- Route 66 State Park
- Saint Louis Galleria Mall
- Sister Marie Charles Park
- Sky Zone Indoor Trampoline Park - St. Louis
- Spooner's Frozen Custard
- St. Jordan Creek Winery
- St. Louis Art Museum
- St. Louis Car Museum
- Visit Edmundson
- St. Louis Zoo
- St. Louis Holidays
- St. Peters Holidays
- Sunset Hills Holidays
- Tower Grove Park
- Wentzville Holidays
- Woodbine Center Shopping Center
- World Chess Hall of Fame
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.
