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Port Saint Lucie Hotel Guide - St. Lucie Medical Center hotels in Port Saint Lucie, United States of America.

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24 Dec - 25 Dec
Tomorrow
25 Dec - 26 Dec
This weekend
26 Dec - 28 Dec
Next weekend
2 Jan - 4 Jan

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Our top choices for St. Lucie Medical Center hotels

Outdoor pool, open 8:00 AM to 10:00 PM, pool umbrellas, pool loungers
Holiday Inn Port St. Lucie by IHG

Holiday Inn Port St. Lucie by IHG

Holiday Inn Port St. Lucie by IHG
3.0 star property
Sandhill Crossing, 1 km from St. Lucie Medical Center
6.8 out of 10, (1001)
"The room was spot less and the staff was very helpful."
United States
Edward
The price is €100
includes taxes & fees
30 Dec - 31 Dec
Holiday Inn Port St. Lucie by IHG
Interior detail
Old Colorado Inn

Old Colorado Inn

Old Colorado Inn
3.5 star property
10.7 km from St. Lucie Medical Center
9.8 out of 10, Exceptional, (679)
"Perfect location. Quaint place to stay."
United States
Stephen
Old Colorado Inn
Desk, free WiFi, bed sheets
Home2 Suites by Hilton Stuart

Home2 Suites by Hilton Stuart

Home2 Suites by Hilton Stuart
3.0 star property
7.9 km from St. Lucie Medical Center
9.4 out of 10, Exceptional, (607)
"Love staying here. The staff are wonderful, the rooms are clean and the breakfast is decent with lots of options. "
United States
Heather
The price is €124
includes taxes & fees
4 Jan - 5 Jan 2026
Home2 Suites by Hilton Stuart
On the beach, sun-loungers, beach umbrellas, beach towels
Hutchinson Shores Resort & Spa

Hutchinson Shores Resort & Spa

Hutchinson Shores Resort & Spa
4.0 star property
10.7 km from St. Lucie Medical Center
9.4 out of 10, Exceptional, (1000)
"Room was clean and comfortable, staff was very kind and helpful, I will definitely visit again "
United States
Andrekiss
The price is €263
includes taxes & fees
1 Jan - 2 Jan 2026
Hutchinson Shores Resort & Spa
Property amenity
Comfort Suites Stuart - Hutchinson Island

Comfort Suites Stuart - Hutchinson Island

Comfort Suites Stuart - Hutchinson Island
3.0 star property
15.6 km from St. Lucie Medical Center
9.6 out of 10, Exceptional, (1004)
"Beautiful place "
United States
Inna
The price is €113
includes taxes & fees
2 Jan - 3 Jan 2026
Comfort Suites Stuart - Hutchinson Island
On the beach
Vistana Beach Club

Vistana Beach Club

Vistana Beach Club
3.5 star property
9.2 km from St. Lucie Medical Center
9.2 out of 10, Wonderful, (119)
"VERY NICE"
United States
Rikke
The price is €219
includes taxes & fees
5 Jan - 6 Jan 2026
Vistana Beach Club
Outdoor pool, pool loungers
Best Western Port St. Lucie

Best Western Port St. Lucie

Best Western Port St. Lucie
2.5 star property
4.3 km from St. Lucie Medical Center
8.6 out of 10, Excellent, (1001)
"Love this place. Great place with a lot of space."
United States
Bradley
The price is €95
includes taxes & fees
28 Dec - 29 Dec
Best Western Port St. Lucie
Free daily buffet breakfast
TownePlace Suites by Marriott Port St. Lucie I-95

TownePlace Suites by Marriott Port St. Lucie I-95

TownePlace Suites by Marriott Port St. Lucie I-95
3.0 star property
Traditions, 13.5 km from St. Lucie Medical Center
9.4 out of 10, Exceptional, (1005)
"Room was clean, friendly staff and good complimentary breakfast"
United States
REX
The price is €119
includes taxes & fees
28 Dec - 29 Dec
TownePlace Suites by Marriott Port St. Lucie I-95
Property amenity
Courtyard by Marriott Port St. Lucie Tradition

Courtyard by Marriott Port St. Lucie Tradition

Courtyard by Marriott Port St. Lucie Tradition
3.0 star property
Traditions, 13.6 km from St. Lucie Medical Center
9.4 out of 10, Exceptional, (487)
"Clean & comfortable!"
United States
Tammy
The price is €132
includes taxes & fees
28 Dec - 29 Dec
Courtyard by Marriott Port St. Lucie Tradition
BBQ/picnic Area
Residence Inn by Marriott Port St. Lucie

Residence Inn by Marriott Port St. Lucie

Residence Inn by Marriott Port St. Lucie
3.0 star property
11.7 km from St. Lucie Medical Center
9.2 out of 10, Wonderful, (1001)
"Great stay! Very friendly staff "
United States
Giovanni
The price is €112
includes taxes & fees
29 Dec - 30 Dec
Residence Inn by Marriott Port St. Lucie
Room, 2 Queen Beds, Balcony, Ocean View
The Lucie

The Lucie

The Lucie
3.0 star property
9.5 km from St. Lucie Medical Center
9.0 out of 10, Wonderful, (1002)
"Great stay, excellent staff. "
United States
Steve
The price is €194
includes taxes & fees
25 Dec - 26 Dec
The Lucie
Property amenity
Hampton Inn & Suites Stuart-North

Hampton Inn & Suites Stuart-North

Hampton Inn & Suites Stuart-North
2.5 star property
8.3 km from St. Lucie Medical Center
8.8 out of 10, Excellent, (1001)
"Staff warm and friendly and helpful with local spots to visit! "
United States
CHRISTY
The price is €123
includes taxes & fees
1 Jan - 2 Jan 2026
Hampton Inn & Suites Stuart-North
Free daily buffet breakfast
Tru by Hilton Port St. Lucie Tradition

Tru by Hilton Port St. Lucie Tradition

Tru by Hilton Port St. Lucie Tradition
2.5 star property
Traditions, 13.6 km from St. Lucie Medical Center
9.2 out of 10, Wonderful, (758)
" I’ve stayed twice and it’s been an excellent experience. Clean facilities and great staff. "
United States
Daniel
The price is €90
includes taxes & fees
4 Jan - 5 Jan 2026
Tru by Hilton Port St. Lucie Tradition
Terrace/patio
Home2 Suites by Hilton Ft. Pierce I-95

Home2 Suites by Hilton Ft. Pierce I-95

Home2 Suites by Hilton Ft. Pierce I-95
3.0 star property
16.9 km from St. Lucie Medical Center
9.4 out of 10, Exceptional, (165)
"Convenient location and good breakfast "
United States
Bruce
The price is €108
includes taxes & fees
30 Dec - 31 Dec
Home2 Suites by Hilton Ft. Pierce I-95
Snack bar
Hilton Garden Inn at PGA Village / Port St. Lucie

Hilton Garden Inn at PGA Village / Port St. Lucie

Hilton Garden Inn at PGA Village / Port St. Lucie
3.0 star property
12.8 km from St. Lucie Medical Center
8.8 out of 10, Excellent, (1000)
"The room was very clean and the staff was friendly and helpful"
United States
Alan
The price is €113
includes taxes & fees
28 Dec - 29 Dec
Hilton Garden Inn at PGA Village / Port St. Lucie
Outdoor pool, pool umbrellas, pool loungers
Sheraton PGA Vacation Resort, Port St. Lucie

Sheraton PGA Vacation Resort, Port St. Lucie

Sheraton PGA Vacation Resort, Port St. Lucie
3.5 star property
12.8 km from St. Lucie Medical Center
9.0 out of 10, Wonderful, (646)
"Was very happy with our stay"
United States
matthew
The price is €135
includes taxes & fees
7 Jan - 8 Jan 2026
Sheraton PGA Vacation Resort, Port St. Lucie
Outdoor pool, pool loungers
Best Western Downtown Stuart

Best Western Downtown Stuart

Best Western Downtown Stuart
3.0 star property
12.1 km from St. Lucie Medical Center
8.6 out of 10, Excellent, (1001)
"Nice hotel for the money"
United States
Rosemary
The price is €111
includes taxes & fees
30 Dec - 31 Dec
Best Western Downtown Stuart
In-room safe, desk, laptop workspace, iron/ironing board
Holiday Inn Express & Suites Port St. Lucie West by IHG

Holiday Inn Express & Suites Port St. Lucie West by IHG

Holiday Inn Express & Suites Port St. Lucie West by IHG
2.5 star property
Saint Lucie West, 11.7 km from St. Lucie Medical Center
8.6 out of 10, Excellent, (1000)
"Clean room, quite, good breakfast made for a nice stay"
United States
Ronald
The price is €103
includes taxes & fees
11 Jan - 12 Jan 2026
Holiday Inn Express & Suites Port St. Lucie West by IHG
Lobby sitting area
Homewood Suites by Hilton Port Saint Lucie-Tradition

Homewood Suites by Hilton Port Saint Lucie-Tradition

Homewood Suites by Hilton Port Saint Lucie-Tradition
3.0 star property
Traditions, 13.7 km from St. Lucie Medical Center
8.8 out of 10, Excellent, (1000)
"Great stay!"
United States
Terry
The price is €114
includes taxes & fees
3 Jan - 4 Jan 2026
Homewood Suites by Hilton Port Saint Lucie-Tradition
Lobby
Fairfield Inn & Suites by Marriott Fort Pierce

Fairfield Inn & Suites by Marriott Fort Pierce

Fairfield Inn & Suites by Marriott Fort Pierce
2.5 star property
16.8 km from St. Lucie Medical Center
8.6 out of 10, Excellent, (1000)
"everything was clean and the breakfast was great"
United States
Jim
The price is €92
includes taxes & fees
29 Dec - 30 Dec
Fairfield Inn & Suites by Marriott Fort Pierce
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top St. Lucie Medical Center Hotel Reviews

Best Western Port St. Lucie

Best Western Port St. Lucie

10/10 Excellent
"Love this place. Great place with a lot of space."
Bradley 1-night trip
Posted 2 weeks ago
Best Western Port St. Lucie

Hotels near other St. Lucie Medical Center attractions

Drone photography of Veterans Memorial Park in Oldsmar, Florida, a waterside park featuring a memorial, a bocce court, fitness equipment, trails, and a gazebo in Tampa Bay

Veterans Memorial Park

4.2/5 (62 reviews)
You can find out about the history of Port Saint Lucie when you stop by Veterans Memorial Park. Stroll along the beautiful beaches or attend a sporting event in this culturally rich area.
See properties
View over Fort Pierce Inlet State Park on the Treasure Coast of Florida in St. Lucie County

St Lucie Inlet State Park

4.5/5 (15 reviews)
Find out about the history of Jensen Beach with a stop at St Lucie Inlet State Park. Wander through the beautiful beaches and waterfront in this culturally rich area.
See properties

Frequently asked questions

What's the area like around St. Lucie Medical Center?
St. Lucie Medical Center is located in Port Saint Lucie. If you're looking for a convenient place to stay, take a look at the 20 hotels and other accommodation options you'll find within a mile.
Where is the best place to stay close to St. Lucie Medical Center?
Holiday Inn Port St. Lucie by IHG is one of the top choices for your stay based on our traveller data, and this hotel offers a restaurant and an outdoor pool. It's located just a short 0.6 mi (1 km) from St. Lucie Medical Center. Another good choice is Best Western Port St. Lucie, located 2.7 mi (4.3 km) away.
How many hotels should I expect to find close to St. Lucie Medical Center?
Expedia has 20 hotels and other accommodation options within a mile from St. Lucie Medical Center.
If I need to cancel the hotel reservation for my stay near St. Lucie Medical Center, will I receive a refund?
Yes, you'll find most hotel reservations are fully refundable if you cancel before the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your check-in date. If you booked a non-refundable reservation, you might still have the option to cancel and receive a refund within a 24-hour period of your booking. Add your dates and click on "Search", then use the filter option "fully refundable" to review the best options available near St. Lucie Medical Center.
What can I see and do near St. Lucie Medical Center?
Local parks like Port St. Lucie Botanical Gardens, River Park Marina and Veterans Memorial Park are peaceful spots to stop and take in some fresh air. Dip your toes in the water at Normandy Beach, Fort Pierce Beach and Herman's Bay Beach. Spend some time exploring the great outdoors at Walton Scrub Preserve, Spruce Bluff Preserve and Ocean Bay Beachside.