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Greenville Hotel Guide. Hotels in Uptown Greenville, Greenville, United States of America

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Check prices for these dates

This weekend
28 Aug - 30 Aug
Next weekend
4 Sept - 6 Sept

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Our top choices for Uptown Greenville hotels

A modern hotel with a stone facade, large windows, and a well-lit entrance.

1. Hilton Garden INN Greenville University

Hilton Garden INN Greenville University
3.0 star property
Uptown Greenville
9.4 out of 10, Exceptional, (161 reviews)
"Best hotel in Greenville with a good restaurant in a great bar."
United States
Mark
The price is €118
includes taxes & fees
13 Sept - 14 Sept
Hilton Garden INN Greenville University
A hotel room with a blue sofa, a wooden coffee table, a white bed, a wall-mounted lamp, and a painting.

2. Holiday Inn Express Greenville by IHG

Holiday Inn Express Greenville by IHG
2.5 star property
2.3 km from Uptown Greenville
8.4 out of 10, Very good, (1,000 reviews)
"Breakfast was top class...Probably the best place we ate on the whole vacation. Nice rooms, nice staff...excellent place to stay"
United States
Tim
The price is €106
includes taxes & fees
30 Aug - 31 Aug
Holiday Inn Express Greenville by IHG
A multi-story hotel with a covered entrance, large windows, and a brick facade.

3. Microtel Inn & Suites by Wyndham Greenville/University Medic

Microtel Inn & Suites by Wyndham Greenville/University Medic
2.0 star property
2.5 km from Uptown Greenville
7.0 out of 10, Good, (1,000 reviews)
"Wonderful staff"
United States
Hipolito
The price is €63
includes taxes & fees
30 Aug - 31 Aug
Microtel Inn & Suites by Wyndham Greenville/University Medic
A circular fire pit with seating around it, a covered patio area, and a brick building in the background.

4. Homewood Suites By Hilton Greenville, NC

Homewood Suites By Hilton Greenville, NC
3.0 star property
2.4 km from Uptown Greenville
9.2 out of 10, Wonderful, (408 reviews)
"It's the next best thing to your comfy home."
United States
William-Karla
The price is €111
includes taxes & fees
3 Sept - 4 Sept
Homewood Suites By Hilton Greenville, NC
A modern dining area with a large window, a chandelier, and a patterned sofa.

5. Quality Inn Greenville near University

Quality Inn Greenville near University
2.5 star property
2 km from Uptown Greenville
7.4 out of 10, Good, (1,001 reviews)
"Nice place 👍"
United States
Dereck
The price is €73
includes taxes & fees
21 Sept - 22 Sept
Quality Inn Greenville near University
An outdoor patio area with a fire pit, seating, and umbrellas.

6. Residence Inn by Marriott Greenville

Residence Inn by Marriott Greenville
3.0 star property
2.4 km from Uptown Greenville
8.8 out of 10, Excellent, (527 reviews)
"The facilities were clean and quiet and the breakfast was good."
United States
Steve
The price is €112
includes taxes & fees
30 Aug - 31 Aug
Residence Inn by Marriott Greenville
An indoor swimming pool with clear markings, a "NO DIVING" sign, and a view of parked cars outside.

7. Fairfield Inn & Suites by Marriott Greenville

Fairfield Inn & Suites by Marriott Greenville
3.0 star property
2.4 km from Uptown Greenville
8.6 out of 10, Excellent, (504 reviews)
"Clean room and nice breakfast!"
United States
Frank
The price is €127
includes taxes & fees
5 Sept - 6 Sept
Fairfield Inn & Suites by Marriott Greenville
A Courtyard by Marriott hotel with a covered entrance, outdoor seating, and a landscaped area.

8. Courtyard Marriott Greenville

Courtyard Marriott Greenville
3.0 star property
Medical District, 2.8 km from Uptown Greenville
8.8 out of 10, Excellent, (933 reviews)
"Great hospitality"
United States
Quentin
The price is €123
includes taxes & fees
31 Aug - 1 Sept
Courtyard Marriott Greenville
A hotel room with a desk, two beds, a sofa, a TV, and a coffee machine.

9. Best Western Plus Suites-Greenville

Best Western Plus Suites-Greenville
2.5 star property
3.9 km from Uptown Greenville
9.0 out of 10, Wonderful, (1,001 reviews)
"Great stay"
United States
Ezekiel
The price is €108
includes taxes & fees
31 Aug - 1 Sept
Best Western Plus Suites-Greenville
A spacious lobby with a stone fireplace, comfortable seating, and a bar area.

10. Staybridge Suites Greenville Medical Center by IHG

Staybridge Suites Greenville Medical Center by IHG
3.0 star property
2.3 km from Uptown Greenville
9.2 out of 10, Wonderful, (357 reviews)
"Awesome Stay !!"
United States
Levi
The price is €123
includes taxes & fees
30 Aug - 31 Aug
Staybridge Suites Greenville Medical Center by IHG
A hotel lobby with a seating area, a coffee table, a potted plant, a television, and a large window with a view of the parking lot.

11. Super 8 by Wyndham Greenville

Super 8 by Wyndham Greenville
2.0 star property
2.3 km from Uptown Greenville
6.6 out of 10, (605 reviews)
"Great place to stay"
United States
ShaQuita
The price is €80
includes taxes & fees
30 Aug - 31 Aug
Super 8 by Wyndham Greenville
A spacious lobby with a high ceiling, a large window, a ceiling fan, a brown leather sofa, a glass coffee table with flowers, a patterned rug, and a red carpet.

12. Econo Lodge Greenville near University

Econo Lodge Greenville near University
2.0 star property
2.3 km from Uptown Greenville
7.2 out of 10, Good, (463 reviews)
"Nice place, is great for a whole family, close to beaches."
United States
Gerardo
The price is €70
includes taxes & fees
1 Sept - 2 Sept
Econo Lodge Greenville near University
A table set with glassware, plates, and cutlery, and a person arranging the table settings.

13. Holiday Inn Greenville by IHG

Holiday Inn Greenville by IHG
3.0 star property
Convention District, 4.3 km from Uptown Greenville
8.8 out of 10, Excellent, (1,000 reviews)
"great place to stay"
United States
Bridget
The price is €93
includes taxes & fees
8 Sept - 9 Sept
Holiday Inn Greenville by IHG
An outdoor patio with seating, potted plants, and a brick fireplace.

14. Hampton Inn Greenville

Hampton Inn Greenville
2.5 star property
Convention District, 4.3 km from Uptown Greenville
9.0 out of 10, Wonderful, (660 reviews)
"The rooms were very clean and spacious. The hot breakfast was delicious and plentiful. Nice hotel."
United States
Judy
The price is €124
includes taxes & fees
3 Sept - 4 Sept
Hampton Inn Greenville
A hotel room with two beds, each with patterned bedding, a bedside table with a lamp, and a framed picture on the wall.

15. Motel 6 Greenville, NC – ECU-Medical Center

Motel 6 Greenville, NC – ECU-Medical Center
2.0 star property
2.2 km from Uptown Greenville
6.6 out of 10, (131 reviews)
"I like that the bed had good covering. Not just a thin sheet and AC worked wonderfully."
United States
Renee
The price is €71
includes taxes & fees
1 Sept - 2 Sept
Motel 6 Greenville, NC – ECU-Medical Center
A hotel entrance with a sign reading 'Candlewood Suites.' There are potted plants and a mailbox in the foreground.

16. Candlewood Suites Greenville NC by IHG

Candlewood Suites Greenville NC by IHG
2.5 star property
4.7 km from Uptown Greenville
8.4 out of 10, Very good, (660 reviews)
"Nice accommodations, staff was very friendly, could use a little updating."
United States
Amanda
The price is €95
includes taxes & fees
30 Aug - 31 Aug
Candlewood Suites Greenville NC by IHG
A spacious lobby with a blue sofa, yellow armchairs, a central coffee table, and a wooden balcony railing.

17. Comfort Inn & Suites Greenville Near East Carolina University

Comfort Inn & Suites Greenville Near East Carolina University
2.5 star property
4.9 km from Uptown Greenville
8.8 out of 10, Excellent, (530 reviews)
"Clean property, helpful and friendly staff, and wonderful breakfast."
United States
Kendall
The price is €106
includes taxes & fees
6 Sept - 7 Sept
Comfort Inn & Suites Greenville Near East Carolina University
A compact living space with a kitchenette, a dining area, and a seating area with a sofa and a coffee table.

18. Affordable Suites Greenville

Affordable Suites Greenville
2.0 star property
3.8 km from Uptown Greenville
8.4 out of 10, Very good, (667 reviews)
"Staff is very helpful and courteous."
United States
Noman
The price is €67
includes taxes & fees
14 Sept - 15 Sept
Affordable Suites Greenville

19. Red Roof Inn Greenville, NC

Red Roof Inn Greenville, NC
2.0 star property
3.4 km from Uptown Greenville
4.8 out of 10, (286 reviews)
"N/A"
United States
Orlando
The price is €62
includes taxes & fees
4 Sept - 5 Sept
Red Roof Inn Greenville, NC
A hotel room with two beds, a red armchair, a sofa, and a desk.

20. Country Inn & Suites by Radisson, Greenville, NC

Country Inn & Suites by Radisson, Greenville, NC
3.0 star property
6.7 km from Uptown Greenville
7.6 out of 10, Good, (913 reviews)
"Clean and comfortable. I had a nice quiet stay."
United States
Lakeisha
The price is €90
includes taxes & fees
16 Sept - 17 Sept
Country Inn & Suites by Radisson, Greenville, NC
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Uptown Greenville

Find the best Uptown Greenville areas for the activities you enjoy most.

University District

While University District isn't home to many top sights, Dowdy–Ficklen Stadium and Williams Arena at Minges Coliseum are some notable places to visit nearby.

Convention District

When in Convention District, you can plan a visit to Williams Arena at Minges Coliseum and Dowdy–Ficklen Stadium, some noteworthy sights in the nearby area.

Medical District

If you're looking for some top things to see and do in Medical District and surrounding area, you can visit North Pines and Arlington Crossing.

Westhaven

Westhaven might not have many top sights, but 11 Galleria and Williams Arena at Minges Coliseum are two attractions nearby that you can check out.

A cityscape with a dense forest in the foreground and a clear blue sky.

College View Historic District

If you're looking for some top things to see and do in College View Historic District and surrounding area, you can visit Williams Arena at Minges Coliseum and Dowdy–Ficklen Stadium.

Top Uptown Greenville Hotel Reviews

Staybridge Suites Greenville Medical Center by IHG

Staybridge Suites Greenville Medical Center by IHG

10/10 Excellent
"The entire staff was so kind and helpful! My room was fantastic!"
Megan 1-night trip
Posted 2 days ago
Staybridge Suites Greenville Medical Center by IHG

Frequently asked questions

What is Uptown Greenville like?
Travellers will be sure to find plenty to entertain them in Greenville's Uptown Greenville neighbourhood. Are you looking for Uptown Greenville travel tips? Make sure that you visit Greenville Museum of Art and Town Common while you're in the neighbourhood.
What's a favourite place to stay in Uptown Greenville?
Based on our traveller data, Hilton Garden INN Greenville University is one of the top choices for your stay in Uptown Greenville. This hotel is a short 3-minute walk from East Carolina University, and it offers a restaurant and a 24-hour fitness centre.
If I need to cancel my hotel reservation in Uptown Greenville, will I receive a refund?
Yes, the majority of hotel room reservations are refundable provided that you cancel before the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of the scheduled arrival. If you have a reservation that's non-refundable, it might still be possible to cancel it and be given a refund within a 24-hour period of booking. Enter dates in and click on "Search", then use the "fully refundable" filter to view top deals in Uptown Greenville.
What is there to do around this Greenville neighbourhood?
A few attractions you might want to check out while you're in Uptown Greenville are Greenville Museum of Art and Town Common. Shepherd Memorial Library - Carver Branch and North Pines are also worth a visit when you're out sightseeing in Greenville.