Uptown Holidays
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Top hotels in Uptown
Hyatt Regency St. Louis at The Arch
315 Chestnut St St. Louis MO
Fully refundableReserve now, pay when you stay
The price is €128 per night from 25 May to 26 May
€128
25 May - 26 May
includes taxes & fees
8.6/10 Excellent! (4,014 reviews)
Great food, great staff!
Reviewed on 24 Apr 2026
Clayton Plaza Hotel & Extended Stay
7750 Carondelet Avenue St. Louis MO
Fully refundableReserve now, pay when you stay
The price is €99 per night from 17 May to 18 May
€99
17 May - 18 May
includes taxes & fees
9/10 Wonderful! (3,156 reviews)
I am a frequent traveler to STL. This is one of my favorite places to stay.
Reviewed on 24 Apr 2026
21C Museum Hotel St Louis
1528 Locust street St. Louis MO
Fully refundableReserve now, pay when you stay
The price is €173 per night from 3 May to 4 May
€173
3 May - 4 May
includes taxes & fees
9/10 Wonderful! (1,782 reviews)
The staff was great and willing to help. They even ran my uber eats up to my room and new key cards. This hotel will be my go-to when back in St. Louis.
Reviewed on 22 Apr 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Things to do
St Louis Self-Guided Driving and Walking Audio Tour
€13
per traveller
St. Louis Ghost Tour: Sinister Sins & Shadows
€28
per adult
Gateway Arch National Park Self Guided Audio Walking Tour
€13
per traveller
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.