Uptown Holidays

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Where to stay in Uptown

Find the best Uptown areas and neighborhoods for the activities you enjoy most. Learn more about Uptown

Top hotels in Uptown

Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

4 out of 5
315 Chestnut St, St. Louis, MO
Fully refundableReserve now, pay when you stay
The price is €131 per night from 23 Aug to 24 Aug
€131
23 Aug - 24 Aug
includes taxes & fees
8.4/10 Very Good! (3,984 reviews)
"Great hotel"

Reviewed on 18 Aug 2025

Hyatt Regency St. Louis at The Arch
Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch

3 out of 5
2 South 4th Street, St. Louis, MO
Fully refundableReserve now, pay when you stay
The price is €136 per night from 2 Sept to 3 Sept
€136
2 Sept - 3 Sept
includes taxes & fees
9.4/10 Exceptional! (2,974 reviews)
"Perfect location"

Reviewed on 20 Aug 2025

Drury Plaza Hotel St. Louis at the Arch
Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

3.5 out of 5
7750 Carondelet Avenue, St. Louis, MO
Fully refundableReserve now, pay when you stay
The price is €109 per night from 31 Aug to 1 Sept
€109
31 Aug - 1 Sept
includes taxes & fees
8.8/10 Excellent! (2,898 reviews)
"Clean rooms excellent staff wonderful on site Breakfast"

Reviewed on 20 Aug 2025

Clayton Plaza Hotel & Extended Stay
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Things to do

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.