Winston-Salem Hotel Guide - Wilkes Regional hotels in Winston-Salem, United States of America.

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Check prices for these dates

Tonight
13 Jan - 14 Jan
Tomorrow
14 Jan - 15 Jan
This weekend
16 Jan - 18 Jan
Next weekend
23 Jan - 25 Jan

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Our top choices for Wilkes Regional hotels

Free continental breakfast
Hampton Inn Winston-Salem Hanes Mall

Hampton Inn Winston-Salem Hanes Mall

Hampton Inn Winston-Salem Hanes Mall
2.5 star property
1 km from Wilkes Regional
9.2 out of 10, Wonderful, (1,001 reviews)
"Super friendly staff, very clean and good breakfast "
United States
jane
The price is €102
includes taxes & fees
25 Jan - 26 Jan
Hampton Inn Winston-Salem Hanes Mall
Restaurant
Home2 Suites by Hilton Winston-Salem Hanes Mall

Home2 Suites by Hilton Winston-Salem Hanes Mall

Home2 Suites by Hilton Winston-Salem Hanes Mall
3.0 star property
1.8 km from Wilkes Regional
9.2 out of 10, Wonderful, (489 reviews)
"Nearby Mall and restaurants"
United States
Pablo
The price is €118
includes taxes & fees
20 Jan - 21 Jan
Home2 Suites by Hilton Winston-Salem Hanes Mall
Pillow-top beds, desk, laptop workspace, blackout curtains
Comfort Suites Hanes Mall

Comfort Suites Hanes Mall

Comfort Suites Hanes Mall
2.5 star property
0.7 km from Wilkes Regional
8.8 out of 10, Excellent, (1,000 reviews)
"Clean rooms, exelent service, great breakfast and the employees."
United States
Yadira
The price is €92
includes taxes & fees
15 Jan - 16 Jan
Comfort Suites Hanes Mall
Restaurant
Springhill Suites by Marriott Winston-Salem Hanes Mall

Springhill Suites by Marriott Winston-Salem Hanes Mall

Springhill Suites by Marriott Winston-Salem Hanes Mall
3.0 star property
1.8 km from Wilkes Regional
9.0 out of 10, Wonderful, (1,000 reviews)
"Check in was quick and easy and the staff was friendly. "
United States
Roxanne
The price is €104
includes taxes & fees
18 Jan - 19 Jan
Springhill Suites by Marriott Winston-Salem Hanes Mall
Exterior
La Quinta Inn & Suites by Wyndham Winston-Salem

La Quinta Inn & Suites by Wyndham Winston-Salem

La Quinta Inn & Suites by Wyndham Winston-Salem
3.0 star property
0.8 km from Wilkes Regional
8.4 out of 10, Very good, (26 reviews)
"Best La Quinta we have stayed at in a few years. Room was great as was the location near other amenities."
United States
Melvin
The price is €68
includes taxes & fees
19 Jan - 20 Jan
La Quinta Inn & Suites by Wyndham Winston-Salem
Lobby
Hilton Garden Inn Winston-Salem/Hanes Mall

Hilton Garden Inn Winston-Salem/Hanes Mall

Hilton Garden Inn Winston-Salem/Hanes Mall
3.0 star property
2.4 km from Wilkes Regional
8.8 out of 10, Excellent, (721 reviews)
"The room was very comfortable ,the staff was friendly and helpful great stay Thank You Jay "
United States
Jay
The price is €115
includes taxes & fees
25 Jan - 26 Jan
Hilton Garden Inn Winston-Salem/Hanes Mall
Business centre
Residence Inn by Marriott Winston-Salem Hanes Mall

Residence Inn by Marriott Winston-Salem Hanes Mall

Residence Inn by Marriott Winston-Salem Hanes Mall
3.0 star property
2.4 km from Wilkes Regional
8.8 out of 10, Excellent, (391 reviews)
"Room was spotless and front desk staff was amazing!!! Breakfast food was ok. Would stay here again"
United States
LaMarr
The price is €112
includes taxes & fees
2 Feb - 3 Feb
Residence Inn by Marriott Winston-Salem Hanes Mall
Exterior
Courtyard by Marriott Winston-Salem Hanes Mall

Courtyard by Marriott Winston-Salem Hanes Mall

Courtyard by Marriott Winston-Salem Hanes Mall
3.0 star property
1.3 km from Wilkes Regional
8.4 out of 10, Very good, (711 reviews)
"Clean Room, nice staff Would definitely stay here again "
United States
Dan
The price is €95
includes taxes & fees
25 Jan - 26 Jan
Courtyard by Marriott Winston-Salem Hanes Mall
Lobby
Sleep Inn Hanes Mall

Sleep Inn Hanes Mall

Sleep Inn Hanes Mall
2.5 star property
Williamsburg Square, 0.9 km from Wilkes Regional
7.8 out of 10, Good, (1,000 reviews)
"Great stay! "
United States
Raphel
The price is €67
includes taxes & fees
26 Jan - 27 Jan
Sleep Inn Hanes Mall
Full-sized fridge, microwave, stovetop
WoodSpring Suites Winston-Salem near Hanes Mall

WoodSpring Suites Winston-Salem near Hanes Mall

WoodSpring Suites Winston-Salem near Hanes Mall
2.5 star property
2 km from Wilkes Regional
7.8 out of 10, Good, (272 reviews)
"Friendly and accommodating staff"
United States
Patrick Thomas
The price is €72
includes taxes & fees
15 Jan - 16 Jan
WoodSpring Suites Winston-Salem near Hanes Mall
Exterior
Best Western Plus Hanes Mall Hotel

Best Western Plus Hanes Mall Hotel

Best Western Plus Hanes Mall Hotel
2.5 star property
2 km from Wilkes Regional
7.6 out of 10, Good, (1,000 reviews)
"Clean and good breakfast friendly staff"
United States
Raymond
The price is €75
includes taxes & fees
18 Jan - 19 Jan
Best Western Plus Hanes Mall Hotel
Room, 2 Double Beds, Non Smoking
Suburban Studios Winston-Salem near Hanes Mall

Suburban Studios Winston-Salem near Hanes Mall

Suburban Studios Winston-Salem near Hanes Mall
2.0 star property
Williamsburg Square, 0.8 km from Wilkes Regional
7.0 out of 10, Good, (284 reviews)
"clean room, staff, allowed me to check is early."
United States
Gary
The price is €55
includes taxes & fees
15 Jan - 16 Jan
Suburban Studios Winston-Salem near Hanes Mall
Lobby
Quality Inn & Suites Hanes Mall

Quality Inn & Suites Hanes Mall

Quality Inn & Suites Hanes Mall
2.5 star property
2.4 km from Wilkes Regional
6.8 out of 10, (1,003 reviews)
"Very nice and friendly check-in experience.. "
United States
Joy
The price is €54
includes taxes & fees
22 Jan - 23 Jan
Quality Inn & Suites Hanes Mall
Exterior
Red Roof Inn Winston-Salem

Red Roof Inn Winston-Salem

Red Roof Inn Winston-Salem
2.0 star property
0.7 km from Wilkes Regional
5.6 out of 10, (431 reviews)
"Clean rooms "
United States
Shirley
The price is €62
includes taxes & fees
15 Jan - 16 Jan
Red Roof Inn Winston-Salem
Staircase
Summit Street Inns

Summit Street Inns

Summit Street Inns
3.5 star property
6.2 km from Wilkes Regional
9.8 out of 10, Exceptional, (232 reviews)
"Great Hotel! Favorite place to stay in Winston Salem."
United States
Pedro
The price is €121
includes taxes & fees
18 Jan - 19 Jan
Summit Street Inns
Courtyard
The Historic Brookstown Inn, Trademark Collection by Wyndham

The Historic Brookstown Inn, Trademark Collection by Wyndham

The Historic Brookstown Inn, Trademark Collection by Wyndham
3.5 star property
6.4 km from Wilkes Regional
9.6 out of 10, Exceptional, (1,005 reviews)
"Amazing historic hotel "
United States
Laura
The price is €112
includes taxes & fees
25 Jan - 26 Jan
The Historic Brookstown Inn, Trademark Collection by Wyndham
Free daily continental breakfast
The Zevely Inn

The Zevely Inn

The Zevely Inn
3.0 star property
6.4 km from Wilkes Regional
9.6 out of 10, Exceptional, (138 reviews)
"Great breakfast - innkeeper gave great suggestions for things to do in the area. "
United States
Regina
The Zevely Inn
Exterior
Holiday Inn Express & Suites Winston Salem Sw Clemmons by IHG

Holiday Inn Express & Suites Winston Salem Sw Clemmons by IHG

Holiday Inn Express & Suites Winston Salem Sw Clemmons by IHG
2.5 star property
7.9 km from Wilkes Regional
9.6 out of 10, Exceptional, (487 reviews)
"Good breakfast and very comfortable bed also very clean"
United States
Joseph
The price is €101
includes taxes & fees
25 Jan - 26 Jan
Holiday Inn Express & Suites Winston Salem Sw Clemmons by IHG
Restaurant
The Shaffner Inn

The Shaffner Inn

The Shaffner Inn
3.0 star property
6.4 km from Wilkes Regional
9.2 out of 10, Wonderful, (202 reviews)
"One of the best B&B we have ever seen"
United States
dale T.
The Shaffner Inn
Free daily buffet breakfast
Hampton Inn & Suites Winston-Salem Downtown

Hampton Inn & Suites Winston-Salem Downtown

Hampton Inn & Suites Winston-Salem Downtown
2.5 star property
6.8 km from Wilkes Regional
9.0 out of 10, Wonderful, (661 reviews)
"Great location good breakfast "
United States
Carlos
The price is €82
includes taxes & fees
25 Jan - 26 Jan
Hampton Inn & Suites Winston-Salem Downtown
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Wilkes Regional Hotel Reviews

Sleep Inn Hanes Mall

Sleep Inn Hanes Mall

10/10 Excellent
"Good breakfast if need anything they were right there. It’s well kept meaning very clean. No complains here I was there from January 9th 2026 til January 11 2026 we’ll be back soon "
Starr 2-night trip
Posted 2 days ago
Sleep Inn Hanes Mall

Hotels near other Wilkes Regional attractions

Hanes Mall

4.2/5 (656 reviews)
You can search for that perfect souvenir at Hanes Mall during your visit to Winston-Salem. Attend a sporting event or simply enjoy the local cheese shops while you're in the area.
See properties

Adventure Landing Winston-Salem

Enjoy an outing to Adventure Landing Winston-Salem during your stay in Winston-Salem. Attend a sporting event or visit the shops in this family-friendly area.
See properties

Frequently asked questions

What's the area like around Wilkes Regional?
Wilkes Regional is located in Winston-Salem. This family-friendly area is known for its array of dining options and sporting events. If you're looking for a convenient place to stay, take a look at the 19 hotels and other accommodation options you'll find within a mile.
What's the best place to stay close to Wilkes Regional?
La Quinta Inn & Suites by Wyndham Winston-Salem is one of the top choices for your stay based on our traveller data, and this hotel offers free breakfast and free parking. It's located just a short 0.5 mi (0.8 km) from Wilkes Regional. Other good options close by include Comfort Suites Hanes Mall and Sleep Inn Hanes Mall.
How many hotels will I find close to Wilkes Regional?
Expedia has 19 hotels and other accommodation options within a mile from Wilkes Regional.
If I need to cancel the hotel reservation for my stay near Wilkes Regional, will I receive a refund?
Yes, most hotel bookings are refundable if you cancel before the hotel's cancellation deadline, which often is within 24-48 hours of check in. If you have a non-refundable reservation, you might still have the option to cancel and receive a refund within 24 hours of booking. Plug in your dates, click on "Search", then use the "fully refundable" filter to get the top deals on offer near Wilkes Regional.
What can I see and do near Wilkes Regional?
Study the collections at Old Salem, Reynolda House Museum of American Art or Southeastern Center for Contemporary Art. You might spend a leisurely day outdoors at Reynolda Gardens and Hobby Park. Attractions like Theatre Alliance and Frank L. Horton Museum Center highlight the local culture.