Zona 21 Holidays

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    Save up to €900 when you book a flight and hotel together*

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    With over 300,000 hotels worldwide, it's easy to create a perfect package

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Where to stay in Zona 21

Find the best Zona 21 areas and neighborhoods for the activities you enjoy most. Learn more about Zona 21
Quetzaltenango Central Park in the morning - Parque a Centro América Xela - Guatemala

Zona 10

2 out of top 10 points of interest in this area

Zona 10 is known for its abundant dining options, and you can plan a trip to Oakland Mall and Avenida La Reforma while you're in town.

Find hotels in Zona 10

Top hotels in Zona 21

Barceló Guatemala City

Barceló Guatemala City

4.5 out of 5
7 Avenida 15-45, Zona 9 Guatemala City Guatemala
Fully refundableReserve now, pay when you stay
The price is €120 per night from 22 Jun to 23 Jun
€120
22 Jun - 23 Jun
includes taxes & fees
9.2/10 Wonderful! (3,320 reviews)
"All the Barcelo team members are very nice, it is a bit expensive when compared to a whole bunch of properties that have sprung up, but the Barcelo Hotel holds a lot of good memories for me, I have been staying there for over 20 years."

Reviewed on 28 May 2026

Barceló Guatemala City
Clarion Suites Guatemala City

Clarion Suites Guatemala City

4 out of 5
14 Street 3-08 Zona 10 Guatemala City Guatemala
Fully refundableReserve now, pay when you stay
The price is €107 per night from 31 May to 1 Jun
€107
31 May - 1 Jun
includes taxes & fees
9.2/10 Wonderful! (1,027 reviews)
"El personal muy amable como siempre. Todo muy bien con mi estadía."

Reviewed on 30 May 2026

Clarion Suites Guatemala City
Hotel Museo Spa Casa Santo Domingo

Hotel Museo Spa Casa Santo Domingo

4.5 out of 5
3a Calle Oriente No 28 A Antigua Guatemala Sacatepequez
Fully refundableReserve now, pay when you stay
The price is €260 per night from 21 Jun to 22 Jun
€260
21 Jun - 22 Jun
includes taxes & fees
9.2/10 Wonderful! (1,061 reviews)
"Hermosas areas verdes."

Reviewed on 24 May 2026

Hotel Museo Spa Casa Santo Domingo
See all 1,251 properties in Zona 21
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Zona 21 holiday package cost?
Live it up in Zona 21 from as low as . Choose from a great selection of hotels, flights and rental cars to suit every budget. Land even better deals when you add a couple of experiences or tours to your holiday package.
How do I get a cheap travel package to Zona 21?
Bundle your bookings with Expedia to save big bucks on your next big adventure. With more than 550 airlines and 1,000,000 hotels worldwide, your Zona 21 holiday package can be customized exactly to suit your budget. With all that extra money, why not include a few interesting experiences and tours? It's an easy way to unlock even more discounts. The holiday you've always dreamed of in Zona 21 is much closer than you thought!
Where should I stay in Zona 21?
With so much to discover in Zona 21, it'd be convenient for you to secure a room in a hotel close to its attractions. Mundo Petapa, Universidad del San Carlos de Guatemala and Embassy of El Salvador are some fascinating ones to add to your itinerary.
What are the top hotels in Zona 21?
House 23 and Beautiful House 20 Minutes From The Airport And 5 Minutes From Mundo Petapa Park are two of the most well-known hotels in Zona 21. Why not look up the amenities and facilities at each and then make a decision?
How far in advance should I book my Zona 21 holiday?
Browse Expedia to compare international flights ASAP. You can generally purchase a ticket up to 12 months in advance. If you can't see your preferred carrier, or you've left things to the last minute, don't worry. The lowest prices to Zona 21 sometimes emerge just weeks before the date of departure.
What does an Expedia Zona 21 travel package include?
Hotels, rental cars and flights, or any combination of them — you decide! Whether you're headed to Zona 21 with the kids or adventuring solo, there's a bundle to suit your budget and style. Once you've made your booking, why not add on a couple of tours as well?
What should I know before booking a Zona 21 travel package?
You'll save plenty with an Expedia travel package. Combine your airfares, rental cars and hotels and unlock exciting discounts. Hotels aren't your only choice, though. Book with us and take your pick of beachside villas, rural cottages and just about everything in between!
Can I choose my airline with a Zona 21 Expedia holiday package?
Yes — and it's easy too. Expedia has access to more than 550 partner airlines around the world. Our holiday packages give you the freedom to pick from available flights, hotels and activities that fit your needs.
If I'm not able to travel, can I cancel my Zona 21 holiday package?
Your situation can change unexpectedly, so yes, you can. You may be able to cancel or amend your Zona 21 holiday package for free within 24 hours of booking. For bookings older than that, you can still cancel or make changes, but your hotel, car rental company or airline may charge additional fees. Want more information? Take a look at our Customer Service Portal. We're here to help make sure your getaway goes off without a hitch.

Popular places to visit

U.S. Embassy in Guatemala

U.S. Embassy in Guatemala is just one of the places to see in Guatemala City, so why not enjoy the other things to explore during your travels? Take in the festivals while you're in the area.

U.S. Embassy in Guatemala

Estadio Nacional Mateo Flores

Catch an event at Estadio Nacional Mateo Flores during your trip to Guatemala City. Make time to visit the area's shops or simply enjoy its top-notch restaurants.

Estadio Nacional Mateo Flores

Things to do

Antigua Guatemala , Full-Day Shared Tour from Guatemala City

Antigua Guatemala Full-Day Shared City Tour

€47
per adult
80% of travellers recommend
Antigua Guatemala Full-Day Shared City Tour
UNESCO JEWEL Antigua Guatemala & Jade Factory Full Day Tour

UNESCO JEWEL Antigua Guatemala & Jade Factory Full Day Tour

€52
per adult
100% of travellers recommend
UNESCO JEWEL Antigua Guatemala & Jade Factory Full Day Tour
Plaza Central

Guatemala City Tour

€69
per adult
100% of travellers recommend
Guatemala City Tour
See all activities in Guatemala City
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.