Cheap flights from Panama starting at €159

View €159 flight on Sun, 10 Aug 2025Opens in a new window

Popular airlines from Panama

  • Avianca

    Avianca

  • United

    United

  • Copa

    Copa

  • American Airlines

    American Airlines

  • Delta

    Delta

  • Aeromexico

    Aeromexico

  • Iberia

    Iberia

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Cheapest flights from Panama

These prices were available within the past 7 days. Prices quoted are per person, return, for the period specified. Prices and availability are subject to change. Additional terms apply.

Copa
Thu, 25 Sep - Mon, 29 Sep
PTY
Panama City
BOG
Bogotá
€259 Return, found 4 days ago
€259
Return
found 4 days ago
Select Copa flight, departing Thu, 25 Sep from Panama City to Bogotá, returning Mon, 29 Sep, priced at €259 found 4 days ago
Copa
Sat, 9 Aug - Sun, 10 Aug
PTY
Panama City
BOG
Bogotá
€262 Return, found 2 days ago
€262
Return
found 2 days ago
Select Copa flight, departing Sat, 9 Aug from Panama City to Bogotá, returning Sun, 10 Aug, priced at €262 found 2 days ago
Copa
Fri, 12 Sep - Tue, 16 Sep
PTY
Panama City
MDE
Medellin
€279 Return, found 5 days ago
€279
Return
found 5 days ago
Select Copa flight, departing Fri, 12 Sep from Panama City to Medellin, returning Tue, 16 Sep, priced at €279 found 5 days ago
Aeromexico
Thu, 18 Sep - Sun, 21 Sep
PTY
Panama City
CUN
Cancun
€280 Return, found 4 days ago
€280
Return
found 4 days ago
Select Aeromexico flight, departing Thu, 18 Sep from Panama City to Cancun, returning Sun, 21 Sep, priced at €280 found 4 days ago
Copa
Tue, 16 Sep - Thu, 18 Sep
PTY
Panama City
MDE
Medellin
€282 Return, found 4 days ago
€282
Return
found 4 days ago
Select Copa flight, departing Tue, 16 Sep from Panama City to Medellin, returning Thu, 18 Sep, priced at €282 found 4 days ago
Copa
Mon, 8 Sep - Thu, 11 Sep
PTY
Panama City
MDE
Medellin
€282 Return, found 3 days ago
€282
Return
found 3 days ago
Select Copa flight, departing Mon, 8 Sep from Panama City to Medellin, returning Thu, 11 Sep, priced at €282 found 3 days ago
Aeromexico
Wed, 17 Dec - Sat, 27 Dec
PTY
Panama City
CUN
Cancun
€284 Return, found 22 hours ago
€284
Return
found 22 hours ago
Select Aeromexico flight, departing Wed, 17 Dec from Panama City to Cancun, returning Sat, 27 Dec, priced at €284 found 22 hours ago
Delta
Thu, 18 Sep - Sun, 21 Sep
PTY
Panama City
MIA
Miami
€386 Return, found 4 days ago
€386
Return
found 4 days ago
Select Delta flight, departing Thu, 18 Sep from Panama City to Miami, returning Sun, 21 Sep, priced at €386 found 4 days ago
avianca
Sun, 14 Sep - Sun, 28 Sep
PTY
Panama City
MDE
Medellin
€402 Return, found 2 hours ago
€402
Return
found 2 hours ago
Select avianca flight, departing Sun, 14 Sep from Panama City to Medellin, returning Sun, 28 Sep, priced at €402 found 2 hours ago
United
Thu, 13 Nov - Mon, 24 Nov
PTY
Panama City
LAX
Los Angeles
€574 Return, found 1 day ago
€574
Return
found 1 day ago
Select United flight, departing Thu, 13 Nov from Panama City to Los Angeles, returning Mon, 24 Nov, priced at €574 found 1 day ago
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