Cheap flights from Panama starting at €158

View €158 flight on Wed, 10 Sep 2025Opens in a new window

Popular airlines from Panama

  • Avianca

    Avianca

  • United

    United

  • Copa

    Copa

  • American Airlines

    American Airlines

  • Delta

    Delta

  • Aeromexico

    Aeromexico

  • KLM

    KLM

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Cheapest flights from Panama

These prices were available within the past 7 days. Prices quoted are per person, return, for the period specified. Prices and availability are subject to change. Additional terms apply.

Aeromexico
Sat, 13 Dec - Wed, 24 Dec
PTY
Panama City
CUN
Cancun
€279 Return, found 20 hours ago
€279
Return
found 20 hours ago
Select Aeromexico flight, departing Sat, 13 Dec from Panama City to Cancun, returning Wed, 24 Dec, priced at €279 found 20 hours ago
Copa
Tue, 2 Sep - Thu, 4 Sep
PTY
Panama City
MDE
Medellin
€280 Return, found 21 hours ago
€280
Return
found 21 hours ago
Select Copa flight, departing Tue, 2 Sep from Panama City to Medellin, returning Thu, 4 Sep, priced at €280 found 21 hours ago
Aeromexico
Tue, 20 Jan - Wed, 28 Jan
PTY
Panama City
CUN
Cancun
€281 Return, found 5 days ago
€281
Return
found 5 days ago
Select Aeromexico flight, departing Tue, 20 Jan from Panama City to Cancun, returning Wed, 28 Jan, priced at €281 found 5 days ago
avianca
Fri, 15 Aug - Fri, 22 Aug
PTY
Panama City
BOG
Bogotá
€299 Return, found 2 days ago
€299
Return
found 2 days ago
Select avianca flight, departing Fri, 15 Aug from Panama City to Bogotá, returning Fri, 22 Aug, priced at €299 found 2 days ago
Aeromexico
Thu, 8 Jan - Wed, 14 Jan
PTY
Panama City
CUN
Cancun
€302 Return, found 3 hours ago
€302
Return
found 3 hours ago
Select Aeromexico flight, departing Thu, 8 Jan from Panama City to Cancun, returning Wed, 14 Jan, priced at €302 found 3 hours ago
Copa
Tue, 2 Sep - Thu, 4 Sep
PTY
Panama City
MDE
Medellin
€314 Return, found 21 hours ago
€314
Return
found 21 hours ago
Select Copa flight, departing Tue, 2 Sep from Panama City to Medellin, returning Thu, 4 Sep, priced at €314 found 21 hours ago
avianca
Fri, 15 Aug - Fri, 22 Aug
PTY
Panama City
BOG
Bogotá
€315 Return, found 2 days ago
€315
Return
found 2 days ago
Select avianca flight, departing Fri, 15 Aug from Panama City to Bogotá, returning Fri, 22 Aug, priced at €315 found 2 days ago
Copa
Tue, 2 Sep - Thu, 4 Sep
PTY
Panama City
MDE
Medellin
€320 Return, found 21 hours ago
€320
Return
found 21 hours ago
Select Copa flight, departing Tue, 2 Sep from Panama City to Medellin, returning Thu, 4 Sep, priced at €320 found 21 hours ago
Delta
Sat, 27 Sep - Fri, 3 Oct
PTY
Panama City
LAX
Los Angeles
€463 Return, found 4 days ago
€463
Return
found 4 days ago
Select Delta flight, departing Sat, 27 Sep from Panama City to Los Angeles, returning Fri, 3 Oct, priced at €463 found 4 days ago
American Airlines
Sat, 27 Sep - Fri, 3 Oct
PTY
Panama City
LAX
Los Angeles
€564 Return, found 4 days ago
€564
Return
found 4 days ago
Select American Airlines flight, departing Sat, 27 Sep from Panama City to Los Angeles, returning Fri, 3 Oct, priced at €564 found 4 days ago
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