Cheap flights from Panama starting at €139

View €139 flight on Fri, 31 Jul 2026Opens in a new window

Popular airlines from Panama

  • Avianca

  • United

  • American Airlines

  • Delta

  • Aeromexico

  • Copa

  • Air Europa

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Cheapest flights from Panama

These prices were available within the past 7 days. Prices quoted are per person, return, for the period specified. Prices and availability are subject to change. Additional terms apply.

Copa
Fri, 31 Jul - Fri, 14 Aug
PTY
Panama City
MDE
Medellín
€264 Return, found 6 days ago
€264
Return
found 6 days ago
Select Copa flight, departing Fri, 31 Jul from Panama City to Medellín, returning Fri, 14 Aug, priced at €264 found 6 days ago
Copa
Fri, 31 Jul - Fri, 14 Aug
PTY
Panama City
MDE
Medellín
€272 Return, found 6 days ago
€272
Return
found 6 days ago
Select Copa flight, departing Fri, 31 Jul from Panama City to Medellín, returning Fri, 14 Aug, priced at €272 found 6 days ago
Copa
Fri, 3 Jul - Mon, 24 Aug
PTY
Panama City
MDE
Medellín
€274 Return, found 5 days ago
€274
Return
found 5 days ago
Select Copa flight, departing Fri, 3 Jul from Panama City to Medellín, returning Mon, 24 Aug, priced at €274 found 5 days ago
avianca
Fri, 31 Jul - Fri, 14 Aug
PTY
Panama City
MDE
Medellín
€291 Return, found 6 days ago
€291
Return
found 6 days ago
Select avianca flight, departing Fri, 31 Jul from Panama City to Medellín, returning Fri, 14 Aug, priced at €291 found 6 days ago
avianca
Fri, 31 Jul - Fri, 14 Aug
PTY
Panama City
MDE
Medellín
€310 Return, found 6 days ago
€310
Return
found 6 days ago
Select avianca flight, departing Fri, 31 Jul from Panama City to Medellín, returning Fri, 14 Aug, priced at €310 found 6 days ago
avianca
Tue, 15 Dec - Wed, 13 Jan
PTY
Panama City
MDE
Medellín
€310 Return, found 2 days ago
€310
Return
found 2 days ago
Select avianca flight, departing Tue, 15 Dec from Panama City to Medellín, returning Wed, 13 Jan, priced at €310 found 2 days ago
Copa
Fri, 31 Jul - Fri, 14 Aug
PTY
Panama City
MDE
Medellín
€318 Return, found 6 days ago
€318
Return
found 6 days ago
Select Copa flight, departing Fri, 31 Jul from Panama City to Medellín, returning Fri, 14 Aug, priced at €318 found 6 days ago
Aeromexico
Wed, 13 Jan - Sat, 16 Jan
PTY
Panama City
CUN
Cancun
€322 Return, found 1 day ago
€322
Return
found 1 day ago
Select Aeromexico flight, departing Wed, 13 Jan from Panama City to Cancun, returning Sat, 16 Jan, priced at €322 found 1 day ago
United
Tue, 21 Jul - Tue, 28 Jul
PTY
Panama City
FLL
Fort Lauderdale
€491 Return, found 2 days ago
€491
Return
found 2 days ago
Select United flight, departing Tue, 21 Jul from Panama City to Fort Lauderdale, returning Tue, 28 Jul, priced at €491 found 2 days ago
Delta
Fri, 28 Aug - Tue, 1 Sept
PTY
Panama City
JFK
New York
€578 Return, found 2 hours ago
€578
Return
found 2 hours ago
Select Delta flight, departing Fri, 28 Aug from Panama City to New York, returning Tue, 1 Sept, priced at €578 found 2 hours ago

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