Cheap Flights from Madrid to San Diego

View €528 flight on Tue, 26 Aug 2025Opens in a new window

Popular airlines from Madrid to San Diego

  • Plan, book, fly with confidence

  • trending down icon
    Be in the know
    Get alerts if flight prices drop or rise*
  • bex rewards loyalty icon
    Book smarter
    Save up to 15% on select hotels after you book a flight*
  • payments icon
    Earn twice
    Earn your airline miles on top of our rewards
    Sign in

Cheap flights from Madrid to San Diego (MAD-SAN)

Prices were available within the past 7 days and start at €528 for one-way flights and €711 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Delta
Thu, 17 Jul - Wed, 30 Jul
MAD
Madrid
SAN
San Diego
€711 Return, found 4 days ago
€711
Return
found 4 days ago
Select Delta flight, departing Thu, 17 Jul from Madrid to San Diego, returning Wed, 30 Jul, priced at €711 found 4 days ago
Virgin Atlantic
Thu, 17 Jul - Wed, 30 Jul
MAD
Madrid
SAN
San Diego
€720 Return, found 4 days ago
€720
Return
found 4 days ago
Select Virgin Atlantic flight, departing Thu, 17 Jul from Madrid to San Diego, returning Wed, 30 Jul, priced at €720 found 4 days ago
Virgin Atlantic
Thu, 17 Jul - Wed, 30 Jul
MAD
Madrid
SAN
San Diego
€744 Return, found 4 days ago
€744
Return
found 4 days ago
Select Virgin Atlantic flight, departing Thu, 17 Jul from Madrid to San Diego, returning Wed, 30 Jul, priced at €744 found 4 days ago
Air France
Thu, 17 Jul - Wed, 30 Jul
MAD
Madrid
SAN
San Diego
€745 Return, found 4 days ago
€745
Return
found 4 days ago
Select Air France flight, departing Thu, 17 Jul from Madrid to San Diego, returning Wed, 30 Jul, priced at €745 found 4 days ago
KLM
Thu, 17 Jul - Wed, 30 Jul
MAD
Madrid
SAN
San Diego
€759 Return, found 4 days ago
€759
Return
found 4 days ago
Select KLM flight, departing Thu, 17 Jul from Madrid to San Diego, returning Wed, 30 Jul, priced at €759 found 4 days ago
JetBlue Airways
Thu, 17 Jul - Wed, 30 Jul
MAD
Madrid
SAN
San Diego
€904 Return, found 4 days ago
€904
Return
found 4 days ago
Select JetBlue Airways flight, departing Thu, 17 Jul from Madrid to San Diego, returning Wed, 30 Jul, priced at €904 found 4 days ago

Find the cheapest month to fly from Madrid (MAD) to San Diego (SAN)

February is typically the cheapest month to fly

From €508 - €1,069 per traveller.

Graph displaying average flight prices per month

*Available to Expedia members.