€475 Cheap Flights Mexico City to Panama City (MEX-PTY)

View €475 flight on Mon, 5 Jan 2026Opens in a new window

Popular airlines from Benito Juarez International Airport (MEX) to Tocumen Intl. Airport (PTY)

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Cheap flights from Mexico City to Panama City (MEX-PTY)

Prices were available within the past 7 days and start at €475 for one-way flights and €508 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Copa
Thu, 18 Dec - Mon, 5 Jan
MEX
Mexico City
PTY
Panama City
€508 Return, found 2 days ago
€508
Return
found 2 days ago
Select Copa flight, departing Thu, 18 Dec from Mexico City to Panama City, returning Mon, 5 Jan, priced at €508 found 2 days ago
Aeromexico
Thu, 18 Dec - Mon, 5 Jan
MEX
Mexico City
PTY
Panama City
€641 Return, found 2 days ago
€641
Return
found 2 days ago
Select Aeromexico flight, departing Thu, 18 Dec from Mexico City to Panama City, returning Mon, 5 Jan, priced at €641 found 2 days ago
avianca
Thu, 18 Dec - Mon, 5 Jan
MEX
Mexico City
PTY
Panama City
€647 Return, found 2 days ago
€647
Return
found 2 days ago
Select avianca flight, departing Thu, 18 Dec from Mexico City to Panama City, returning Mon, 5 Jan, priced at €647 found 2 days ago
avianca
Thu, 18 Dec - Mon, 5 Jan
MEX
Mexico City
PTY
Panama City
€653 Return, found 2 days ago
€653
Return
found 2 days ago
Select avianca flight, departing Thu, 18 Dec from Mexico City to Panama City, returning Mon, 5 Jan, priced at €653 found 2 days ago
avianca
Thu, 18 Dec - Mon, 5 Jan
MEX
Mexico City
PTY
Panama City
€663 Return, found 2 days ago
€663
Return
found 2 days ago
Select avianca flight, departing Thu, 18 Dec from Mexico City to Panama City, returning Mon, 5 Jan, priced at €663 found 2 days ago
avianca
Thu, 18 Dec - Mon, 5 Jan
MEX
Mexico City
PTY
Panama City
€663 Return, found 2 days ago
€663
Return
found 2 days ago
Select avianca flight, departing Thu, 18 Dec from Mexico City to Panama City, returning Mon, 5 Jan, priced at €663 found 2 days ago
avianca
Thu, 18 Dec - Mon, 5 Jan
MEX
Mexico City
PTY
Panama City
€669 Return, found 2 days ago
€669
Return
found 2 days ago
Select avianca flight, departing Thu, 18 Dec from Mexico City to Panama City, returning Mon, 5 Jan, priced at €669 found 2 days ago
avianca
Thu, 18 Dec - Mon, 5 Jan
MEX
Mexico City
PTY
Panama City
€679 Return, found 2 days ago
€679
Return
found 2 days ago
Select avianca flight, departing Thu, 18 Dec from Mexico City to Panama City, returning Mon, 5 Jan, priced at €679 found 2 days ago
American Airlines
Thu, 18 Dec - Mon, 5 Jan
MEX
Mexico City
PTY
Panama City
€1,051 Return, found 2 days ago
€1,051
Return
found 2 days ago
Select American Airlines flight, departing Thu, 18 Dec from Mexico City to Panama City, returning Mon, 5 Jan, priced at €1,051 found 2 days ago
United
Thu, 18 Dec - Mon, 5 Jan
MEX
Mexico City
PTY
Panama City
€1,287 Return, found 2 days ago
€1,287
Return
found 2 days ago
Select United flight, departing Thu, 18 Dec from Mexico City to Panama City, returning Mon, 5 Jan, priced at €1,287 found 2 days ago

Find the cheapest month to fly from Mexico City (MEX) to Panama City (PTY)

August is typically the cheapest month to fly

From €237 - €414 per traveller.

Graph displaying average flight prices per month

Mexico City to Panama City route information
Origin airport
Mexico City Intl.
Destination airport
Tocumen Intl.
Return price
€508
Distance
2397 km
Average flight time
4 hours 45 mins

Perfect flights from Mexico City to Panama City

Embark on an unforgettable journey without breaking the bank with Expedia's incredible deals on cheap flights from Mexico City to Panama City. Whether you're aching for a romantic escape with your partner, craving an adventurous solo expedition, or yearning to immerse yourself in the local history and culture, we've got you covered.
 
Picture yourself strolling through the streets of , surrounded by breathtaking architecture and absorbing the vibrant atmosphere of this captivating city. Indulge in the mouth-watering local specialties, from tantalizing street food to exquisite fine dining. With Expedia, you can experience all of this and more, without sacrificing your budget.
 
Our flexible Mexico City Intl. to Tocumen Intl. ticket options cater to your travel preferences, with incredible one-way fares from €475 and roundtrip prices from €508. Whether you're planning a short city break or a longer adventure, our dynamic pricing ensures that you find the best deals for your journey.
 
But the magic doesn't stop there. Expedia offers a range of partner services to enhance your trip. Rent a car at Tocumen Intl. and explore and its surrounding areas at your own pace. Discover hidden gems off the beaten path, and create unforgettable memories. We also provide a handpicked selection of accommodations, from charming bed and breakfasts to luxury hotels, ensuring that you have a comfortable and memorable stay.
 
Planning your next great adventure is a breeze with Expedia. Our user-friendly platform, unbeatable prices, and round-the-clock customer support are designed to make your travel experience seamless and stress-free. So, why wait? Book your to travel arrangements today and embark on the journey of a lifetime in Panama City.

Frequently asked questions

How much is a flight from Benito Juárez Intl. Airport to PTY?
If you're planning on travelling from Benito Juárez Intl. Airport to Panama Airport, round-trip journeys start from €508. This price is based on fares advertised within the last 7 days on Expedia for flights departing within the next year, so don't let a good deal slip through your fingers. Book today and save yourself money and time. Prices and availability are subject to change. Additional terms apply.
Do I need to pay a cancellation fee if I cancel my flight from MEX to PTY?
Most flights can be cancelled online, but whether or not you incur a fee varies between airlines. If you do need to cancel your getaway, follow the instructions in the Customer Service Portal.
How do I find cheap flights from Mexico Airport to PTY that have flexible change policies?
Many airlines offer the option to reschedule your flight without a change fee. All you pay is the difference between the original flight and the new flight. When you're searching for Benito Juárez Intl. Airport to Panama Airport flights, you'll see a "no change fees" filter for you to select.
How far is the flight from MEX to Tocumen Intl. Airport (PTY)?
The flight distance between Mexico Airport and Tocumen Intl. Airport (PTY) is 2,400 kilometres. Listen to some music or finish off your latest read and the journey will whiz by.
Which airlines fly direct from MEX to PTY?
If you'd like to fly directly from Benito Juárez Intl. Airport to Panama Airport, Copa Airlines (CM) is a top option. It operates 152 flights every month between Mexico City and Tocumen.
Are Mexico City Intl. Airport (MEX) to Tocumen Intl. Airport (PTY) flight tickets cheaper when they're purchased at the last minute?
Booking last minute from MEX to Tocumen Intl. Airport (PTY) can be hit-or-miss. It is possible to score a bargain, but you could also miss out entirely! If you'd rather play it safe and start your trip planning early on, Expedia compares flight deals up to 12 months in advance. Just remember that not all airlines publish their prices that far in advance. Our suggestion? Check back often as updates are made frequently.

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