Cheap Flights from St. Louis to San Diego

View €132 flight on Sat, 20 Sep 2025Opens in a new window

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Cheap flights from St. Louis to San Diego (STL-SAN)

Prices were available within the past 7 days and start at €132 for one-way flights and €231 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Delta
Sat, 20 Sep - Sat, 27 Sep
STL
St. Louis
SAN
San Diego
€231 Return, found 5 days ago
€231
Return
found 5 days ago
Select Delta flight, departing Sat, 20 Sep from St. Louis to San Diego, returning Sat, 27 Sep, priced at €231 found 5 days ago
Delta
Sat, 20 Sep - Sat, 27 Sep
STL
St. Louis
SAN
San Diego
€255 Return, found 5 days ago
€255
Return
found 5 days ago
Select Delta flight, departing Sat, 20 Sep from St. Louis to San Diego, returning Sat, 27 Sep, priced at €255 found 5 days ago
American Airlines
Sat, 20 Sep - Sat, 27 Sep
STL
St. Louis
SAN
San Diego
€263 Return, found 5 days ago
€263
Return
found 5 days ago
Select American Airlines flight, departing Sat, 20 Sep from St. Louis to San Diego, returning Sat, 27 Sep, priced at €263 found 5 days ago
Delta
Sat, 20 Sep - Sat, 27 Sep
STL
St. Louis
SAN
San Diego
€263 Return, found 5 days ago
€263
Return
found 5 days ago
Select Delta flight, departing Sat, 20 Sep from St. Louis to San Diego, returning Sat, 27 Sep, priced at €263 found 5 days ago
Delta
Sat, 20 Sep - Sat, 27 Sep
STL
St. Louis
SAN
San Diego
€264 Return, found 5 days ago
€264
Return
found 5 days ago
Select Delta flight, departing Sat, 20 Sep from St. Louis to San Diego, returning Sat, 27 Sep, priced at €264 found 5 days ago
United
Sat, 20 Sep - Sat, 27 Sep
STL
St. Louis
SAN
San Diego
€268 Return, found 5 days ago
€268
Return
found 5 days ago
Select United flight, departing Sat, 20 Sep from St. Louis to San Diego, returning Sat, 27 Sep, priced at €268 found 5 days ago

Find the cheapest month to fly from St. Louis (STL) to San Diego (SAN)

September is typically the cheapest month to fly

From €102 - €260 per traveller.

Graph displaying average flight prices per month

*Available to Expedia members.