Cheap Flights from Rome to San Diego

View €759 flight on Sun, 14 Sep 2025Opens in a new window

Popular airlines from Rome to San Diego

  • Plan, book, fly with confidence

  • trending down icon
    Be in the know
    Get alerts if flight prices drop or rise*
  • bex rewards loyalty icon
    Book smarter
    Save up to 15% on select hotels after you book a flight*
  • payments icon
    Earn twice
    Earn your airline miles on top of our rewards
    Sign in

Cheap flights from Rome to San Diego (ROM-SAN)

Prices were available within the past 7 days and start at €759 for one-way flights and €864 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

KLM
Sun, 6 Jul - Sat, 12 Jul
FCO
Rome
SAN
San Diego
€864 Return, found 4 days ago
€864
Return
found 4 days ago
Select KLM flight, departing Sun, 6 Jul from Rome to San Diego, returning Sat, 12 Jul, priced at €864 found 4 days ago
KLM
Sun, 6 Jul - Sat, 12 Jul
FCO
Rome
SAN
San Diego
€890 Return, found 4 days ago
€890
Return
found 4 days ago
Select KLM flight, departing Sun, 6 Jul from Rome to San Diego, returning Sat, 12 Jul, priced at €890 found 4 days ago
Iberia
Mon, 30 Jun - Sat, 5 Jul
FCO
Rome
SAN
San Diego
€913 Return, found 4 days ago
€913
Return
found 4 days ago
Select Iberia flight, departing Mon, 30 Jun from Rome to San Diego, returning Sat, 5 Jul, priced at €913 found 4 days ago
United
Sun, 6 Jul - Sat, 12 Jul
FCO
Rome
SAN
San Diego
€971 Return, found 4 days ago
€971
Return
found 4 days ago
Select United flight, departing Sun, 6 Jul from Rome to San Diego, returning Sat, 12 Jul, priced at €971 found 4 days ago
Delta
Sun, 6 Jul - Sat, 12 Jul
FCO
Rome
SAN
San Diego
€982 Return, found 4 days ago
€982
Return
found 4 days ago
Select Delta flight, departing Sun, 6 Jul from Rome to San Diego, returning Sat, 12 Jul, priced at €982 found 4 days ago
Lufthansa
Sun, 6 Jul - Sat, 12 Jul
FCO
Rome
SAN
San Diego
€990 Return, found 4 days ago
€990
Return
found 4 days ago
Select Lufthansa flight, departing Sun, 6 Jul from Rome to San Diego, returning Sat, 12 Jul, priced at €990 found 4 days ago

Find the cheapest month to fly from Rome (ROM) to San Diego (SAN)

May is typically the cheapest month to fly

From €628 - €914 per traveller.

Graph displaying average flight prices per month

*Available to Expedia members.