Cheap flights from Madre de Dios Region starting at €32

View €32 flight on Mon, 1 Jun 2026Opens in a new window

Popular airlines from Madre de Dios Region

  • LATAM Airlines Group

    LATAM Airlines Group

  • Sky Airlines

    Sky Airlines

  • Aerolineas Argentinas

    Aerolineas Argentinas

  • Iberia

    Iberia

  • Aeromexico

    Aeromexico

  • notification illustration

    Be in the know

    Get alerts if flight prices drop or rise*
  • deals illustration

    Book smarter

    Save up to 15% on select hotels after you book a flight*
  • trophy illustration

    Earn twice

    Earn your airline miles on top of our rewards
    Sign in

Cheapest flights from Madre de Dios Region

These prices were available within the past 7 days. Prices quoted are per person, return, for the period specified. Prices and availability are subject to change. Additional terms apply.

LATAM Airlines Group
Fri, 20 Mar - Mon, 23 Mar
PEM
Puerto Maldonado
CUZ
Cusco
€63 Return, found 4 days ago
€63
Return
found 4 days ago
Select LATAM Airlines Group flight, departing Fri, 20 Mar from Puerto Maldonado to Cusco, returning Mon, 23 Mar, priced at €63 found 4 days ago
LATAM Airlines Group
Fri, 20 Mar - Mon, 23 Mar
PEM
Puerto Maldonado
CUZ
Cusco
€68 Return, found 4 days ago
€68
Return
found 4 days ago
Select LATAM Airlines Group flight, departing Fri, 20 Mar from Puerto Maldonado to Cusco, returning Mon, 23 Mar, priced at €68 found 4 days ago
LATAM Airlines Group
Fri, 20 Mar - Mon, 23 Mar
PEM
Puerto Maldonado
CUZ
Cusco
€124 Return, found 4 days ago
€124
Return
found 4 days ago
Select LATAM Airlines Group flight, departing Fri, 20 Mar from Puerto Maldonado to Cusco, returning Mon, 23 Mar, priced at €124 found 4 days ago
LATAM Airlines Group
Fri, 20 Mar - Mon, 23 Mar
PEM
Puerto Maldonado
CUZ
Cusco
€130 Return, found 4 days ago
€130
Return
found 4 days ago
Select LATAM Airlines Group flight, departing Fri, 20 Mar from Puerto Maldonado to Cusco, returning Mon, 23 Mar, priced at €130 found 4 days ago
LATAM Airlines Group
Fri, 20 Mar - Mon, 23 Mar
PEM
Puerto Maldonado
CUZ
Cusco
€202 Return, found 4 days ago
€202
Return
found 4 days ago
Select LATAM Airlines Group flight, departing Fri, 20 Mar from Puerto Maldonado to Cusco, returning Mon, 23 Mar, priced at €202 found 4 days ago
LATAM Airlines Group
Fri, 20 Mar - Mon, 23 Mar
PEM
Puerto Maldonado
CUZ
Cusco
€212 Return, found 4 days ago
€212
Return
found 4 days ago
Select LATAM Airlines Group flight, departing Fri, 20 Mar from Puerto Maldonado to Cusco, returning Mon, 23 Mar, priced at €212 found 4 days ago

Explore a world of travel with Expedia

*Available to Expedia members.