Cheap flights from Guna Yala starting at €129

View €129 flight on Tue, 16 Dec 2025Opens in a new window

Popular airlines from Guna Yala

  • Avianca

    Avianca

  • United

    United

  • Copa

    Copa

  • American Airlines

    American Airlines

  • Aeromexico

    Aeromexico

  • Delta

    Delta

  • Turkish Airlines

    Turkish Airlines

  • notification illustration

    Be in the know

    Get alerts if flight prices drop or rise*
  • deals illustration

    Book smarter

    Save up to 15% on select hotels after you book a flight*
  • trophy illustration

    Earn twice

    Earn your airline miles on top of our rewards
    Sign in

Cheapest flights from Guna Yala

These prices were available within the past 7 days. Prices quoted are per person, return, for the period specified. Prices and availability are subject to change. Additional terms apply.

avianca
Tue, 16 Dec - Sun, 21 Dec
PTY
Panama City
MDE
Medellin
€243 Return, found 1 day ago
€243
Return
found 1 day ago
Select avianca flight, departing Tue, 16 Dec from Panama City to Medellin, returning Sun, 21 Dec, priced at €243 found 1 day ago
Copa
Fri, 6 Feb - Sun, 8 Feb
PTY
Panama City
MDE
Medellin
€250 Return, found 4 days ago
€250
Return
found 4 days ago
Select Copa flight, departing Fri, 6 Feb from Panama City to Medellin, returning Sun, 8 Feb, priced at €250 found 4 days ago
avianca
Tue, 16 Dec - Sun, 21 Dec
PTY
Panama City
MDE
Medellin
€252 Return, found 1 day ago
€252
Return
found 1 day ago
Select avianca flight, departing Tue, 16 Dec from Panama City to Medellin, returning Sun, 21 Dec, priced at €252 found 1 day ago
Copa
Fri, 6 Feb - Sun, 8 Feb
PTY
Panama City
MDE
Medellin
€260 Return, found 4 days ago
€260
Return
found 4 days ago
Select Copa flight, departing Fri, 6 Feb from Panama City to Medellin, returning Sun, 8 Feb, priced at €260 found 4 days ago
Aeromexico
Fri, 6 Feb - Sun, 8 Feb
PTY
Panama City
CUN
Cancun
€282 Return, found 4 days ago
€282
Return
found 4 days ago
Select Aeromexico flight, departing Fri, 6 Feb from Panama City to Cancun, returning Sun, 8 Feb, priced at €282 found 4 days ago
Copa
Fri, 6 Feb - Sun, 8 Feb
PTY
Panama City
MDE
Medellin
€292 Return, found 4 days ago
€292
Return
found 4 days ago
Select Copa flight, departing Fri, 6 Feb from Panama City to Medellin, returning Sun, 8 Feb, priced at €292 found 4 days ago
Copa
Fri, 6 Feb - Sun, 8 Feb
PTY
Panama City
MDE
Medellin
€301 Return, found 4 days ago
€301
Return
found 4 days ago
Select Copa flight, departing Fri, 6 Feb from Panama City to Medellin, returning Sun, 8 Feb, priced at €301 found 4 days ago
Copa
Wed, 24 Dec - Wed, 31 Dec
PTY
Panama City
BOG
Bogotá
€305 Return, found 19 hours ago
€305
Return
found 19 hours ago
Select Copa flight, departing Wed, 24 Dec from Panama City to Bogotá, returning Wed, 31 Dec, priced at €305 found 19 hours ago
American Airlines
Fri, 21 Nov - Tue, 25 Nov
PTY
Panama City
MIA
Miami
€610 Return, found 2 days ago
€610
Return
found 2 days ago
Select American Airlines flight, departing Fri, 21 Nov from Panama City to Miami, returning Tue, 25 Nov, priced at €610 found 2 days ago
United
Fri, 21 Nov - Tue, 25 Nov
PTY
Panama City
MIA
Miami
€633 Return, found 2 days ago
€633
Return
found 2 days ago
Select United flight, departing Fri, 21 Nov from Panama City to Miami, returning Tue, 25 Nov, priced at €633 found 2 days ago

Explore a world of travel with Expedia

*Available to Expedia members.