Cheap flights from Isla Colon starting at €154

View €154 flight on Tue, 16 Sep 2025Opens in a new window

Popular airlines

  • United

    United

  • American Airlines

    American Airlines

  • KLM

    KLM

  • Delta

    Delta

  • Avianca

    Avianca

  • Air France

    Air France

  • Air Europa

    Air Europa

  • Plan, book, fly with confidence

  • trending down icon

    Be in the know

    Get alerts if flight prices drop or rise*
  • bex rewards loyalty icon

    Book smarter

    Save up to 15% on select hotels after you book a flight*
  • payments icon

    Earn twice

    Earn your airline miles on top of our rewards
    Sign in

Cheapest flights from Isla Colon

These prices were available within the past 7 days. Prices quoted are per person, return, for the period specified. Prices and availability are subject to change. Additional terms apply.

Aeromexico
Fri, 12 Dec - Tue, 23 Dec
PTY
Panama City
CUN
Cancun
€275 Return, found 2 days ago
€275
Return
found 2 days ago
Select Aeromexico flight, departing Fri, 12 Dec from Panama City to Cancun, returning Tue, 23 Dec, priced at €275 found 2 days ago
Copa
Fri, 22 Aug - Thu, 28 Aug
PTY
Panama City
MDE
Medellin
€277 Return, found 3 days ago
€277
Return
found 3 days ago
Select Copa flight, departing Fri, 22 Aug from Panama City to Medellin, returning Thu, 28 Aug, priced at €277 found 3 days ago
Copa
Fri, 12 Sep - Tue, 16 Sep
PTY
Panama City
MDE
Medellin
€279 Return, found 17 hours ago
€279
Return
found 17 hours ago
Select Copa flight, departing Fri, 12 Sep from Panama City to Medellin, returning Tue, 16 Sep, priced at €279 found 17 hours ago
Copa
Fri, 22 Aug - Thu, 28 Aug
PTY
Panama City
MDE
Medellin
€311 Return, found 3 days ago
€311
Return
found 3 days ago
Select Copa flight, departing Fri, 22 Aug from Panama City to Medellin, returning Thu, 28 Aug, priced at €311 found 3 days ago
Copa
Fri, 12 Sep - Tue, 16 Sep
PTY
Panama City
MDE
Medellin
€313 Return, found 17 hours ago
€313
Return
found 17 hours ago
Select Copa flight, departing Fri, 12 Sep from Panama City to Medellin, returning Tue, 16 Sep, priced at €313 found 17 hours ago
Delta
Wed, 29 Oct - Tue, 4 Nov
PTY
Panama City
MIA
Miami
€324 Return, found 5 days ago
€324
Return
found 5 days ago
Select Delta flight, departing Wed, 29 Oct from Panama City to Miami, returning Tue, 4 Nov, priced at €324 found 5 days ago
Copa
Fri, 22 Aug - Thu, 28 Aug
PTY
Panama City
MDE
Medellin
€340 Return, found 3 days ago
€340
Return
found 3 days ago
Select Copa flight, departing Fri, 22 Aug from Panama City to Medellin, returning Thu, 28 Aug, priced at €340 found 3 days ago
Copa
Fri, 12 Sep - Tue, 16 Sep
PTY
Panama City
MDE
Medellin
€343 Return, found 17 hours ago
€343
Return
found 17 hours ago
Select Copa flight, departing Fri, 12 Sep from Panama City to Medellin, returning Tue, 16 Sep, priced at €343 found 17 hours ago
avianca
Fri, 22 Aug - Thu, 28 Aug
PTY
Panama City
MDE
Medellin
€358 Return, found 3 days ago
€358
Return
found 3 days ago
Select avianca flight, departing Fri, 22 Aug from Panama City to Medellin, returning Thu, 28 Aug, priced at €358 found 3 days ago
American Airlines
Sat, 13 Sep - Sun, 14 Sep
PTY
Panama City
MIA
Miami
€398 Return, found 4 days ago
€398
Return
found 4 days ago
Select American Airlines flight, departing Sat, 13 Sep from Panama City to Miami, returning Sun, 14 Sep, priced at €398 found 4 days ago

Flights from Isla Colon: Essential Travel Information

Cheapest flight from Isla Colon
€275 (roundtrip)
Best airlines to fly from Isla Colon
avianca, Copa, Delta, American Airlines, United, Aeromexico
Cheapest month to fly from Isla Colon
December
Isla Colon IATA code
PAC
Isla Colon Country/State
Bocas del Toro Province
Airline ticket deals from Isla Colon
€275 - €398

 

*Available to Expedia members.