
Popular airlines from Chicago O'Hare Intl. Airport (ORD) to Tocumen Intl. Airport (PTY)
- Avianca
Avianca
- Copa
Copa
- United
United
- American Airlines
American Airlines
- Delta
Delta
- Plan, book, fly with confidence
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Cheap flights from Chicago to Panama City (ORD-PTY)
Prices were available within the past 7 days and start at €341 for one-way flights and €552 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Fri, 5 Dec - Fri, 12 Dec
ORD
Chicago
PTY
Panama City
€552 Return, found 5 days ago
€552
Return
found 5 days ago

Sat, 17 Jan - Mon, 19 Jan
ORD
Chicago
PTY
Panama City
€565 Return, found 4 days ago
€565
Return
found 4 days ago

Fri, 5 Dec - Fri, 12 Dec
ORD
Chicago
PTY
Panama City
€578 Return, found 5 days ago
€578
Return
found 5 days ago

Fri, 5 Dec - Fri, 12 Dec
ORD
Chicago
PTY
Panama City
€582 Return, found 5 days ago
€582
Return
found 5 days ago

Fri, 5 Dec - Fri, 12 Dec
ORD
Chicago
PTY
Panama City
€599 Return, found 5 days ago
€599
Return
found 5 days ago

Fri, 5 Dec - Fri, 12 Dec
ORD
Chicago
PTY
Panama City
€629 Return, found 5 days ago
€629
Return
found 5 days ago

Fri, 21 Nov - Sat, 29 Nov
ORD
Chicago
PTY
Panama City
€634 Return, found 6 days ago
€634
Return
found 6 days ago

Fri, 5 Dec - Fri, 12 Dec
ORD
Chicago
PTY
Panama City
€642 Return, found 5 days ago
€642
Return
found 5 days ago

Thu, 15 Jan - Tue, 20 Jan
ORD
Chicago
PTY
Panama City
€659 Return, found 6 days ago
€659
Return
found 6 days ago

Wed, 14 Jan - Mon, 19 Jan
ORD
Chicago
PTY
Panama City
€739 Return, found 6 days ago
€739
Return
found 6 days ago
Find the cheapest month to fly from Chicago (ORD) to Panama City (PTY)
February is typically the cheapest month to fly
From €287 - €515 per traveller.
Graph displaying average flight prices per month
Origin airport | O'Hare Intl. |
Destination airport | Tocumen Intl. |
Airlines serving | American Airlines, Copa, Delta, United |
Return price | €551 |
Distance | 3731 km |
Average flight time | 5 hours 23 mins |
Perfect flights from Chicago to Panama City
Embark on an unforgettable journey without breaking the bank with Expedia's incredible deals on cheap flights from Chicago to Panama City. Whether you're aching for a romantic escape with your partner, craving an adventurous solo expedition, or yearning to immerse yourself in the local history and culture, we've got you covered.
Picture yourself strolling through the streets of , surrounded by breathtaking architecture and absorbing the vibrant atmosphere of this captivating city. Indulge in the mouth-watering local specialties, from tantalizing street food to exquisite fine dining. With Expedia, you can experience all of this and more, without sacrificing your budget.
Our flexible O'Hare Intl. to Tocumen Intl. ticket options cater to your travel preferences, with incredible one-way fares from €341 and roundtrip prices from €552. Whether you're planning a short city break or a longer adventure, our dynamic pricing ensures that you find the best deals for your journey.
But the magic doesn't stop there. Expedia offers a range of partner services to enhance your trip. Rent a car at Tocumen Intl. and explore and its surrounding areas at your own pace. Discover hidden gems off the beaten path, and create unforgettable memories. We also provide a handpicked selection of accommodations, from charming bed and breakfasts to luxury hotels, ensuring that you have a comfortable and memorable stay.
Planning your next great adventure is a breeze with Expedia. Our user-friendly platform, unbeatable prices, and round-the-clock customer support are designed to make your travel experience seamless and stress-free. So, why wait? Book your to travel arrangements today and embark on the journey of a lifetime in Panama City.
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Top Routes to Panama City
Top Routes from Chicago
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