Photo by Krystalene Clough

Popular airlines from San Francisco Intl. Airport (SFO) to McGhee Tyson Airport (TYS)
- American Airlines
American Airlines
- Delta
Delta
- United
United
- Frontier Airlines
Frontier Airlines
- Alaska Airlines
Alaska Airlines
- Plan, book, fly with confidence
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Cheap flights from San Francisco to Knoxville (SFO-TYS)
Prices were available within the past 7 days and start at €134 for one-way flights and €310 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Mon, 8 Sep - Mon, 15 Sep
SFO
San Francisco
TYS
Knoxville
€310 Return, found 13 hours ago
€310
Return
found 13 hours ago

Mon, 8 Sep - Mon, 15 Sep
SFO
San Francisco
TYS
Knoxville
€322 Return, found 13 hours ago
€322
Return
found 13 hours ago

Mon, 8 Sep - Mon, 15 Sep
SFO
San Francisco
TYS
Knoxville
€329 Return, found 13 hours ago
€329
Return
found 13 hours ago

Mon, 8 Sep - Mon, 15 Sep
SFO
San Francisco
TYS
Knoxville
€349 Return, found 13 hours ago
€349
Return
found 13 hours ago

Mon, 8 Sep - Mon, 15 Sep
SFO
San Francisco
TYS
Knoxville
€352 Return, found 13 hours ago
€352
Return
found 13 hours ago

Mon, 8 Sep - Mon, 15 Sep
SFO
San Francisco
TYS
Knoxville
€353 Return, found 13 hours ago
€353
Return
found 13 hours ago

Mon, 8 Sep - Mon, 15 Sep
SFO
San Francisco
TYS
Knoxville
€366 Return, found 13 hours ago
€366
Return
found 13 hours ago

Mon, 8 Sep - Mon, 15 Sep
SFO
San Francisco
TYS
Knoxville
€374 Return, found 13 hours ago
€374
Return
found 13 hours ago

Mon, 8 Sep - Mon, 15 Sep
SFO
San Francisco
TYS
Knoxville
€378 Return, found 13 hours ago
€378
Return
found 13 hours ago

Mon, 8 Sep - Mon, 15 Sep
SFO
San Francisco
TYS
Knoxville
€380 Return, found 13 hours ago
€380
Return
found 13 hours ago
Find the cheapest month to fly from San Francisco (SFO) to Knoxville (TYS)
January is typically the cheapest month to fly
From €136 - €465 per traveller.
Graph displaying average flight prices per month
Origin airport | San Francisco Intl. |
Destination airport | McGhee Tyson |
Airlines serving | American Airlines, Delta, United |
Return price | €310 |
Distance | 3385 km |
Perfect flights from San Francisco to Knoxville
Embark on an unforgettable journey without breaking the bank with Expedia's incredible deals on cheap flights from San Francisco to Knoxville. Whether you're aching for a romantic escape with your partner, craving an adventurous solo expedition, or yearning to immerse yourself in the local history and culture, we've got you covered.
Picture yourself strolling through the streets of , surrounded by breathtaking architecture and absorbing the vibrant atmosphere of this captivating city. Indulge in the mouth-watering local specialties, from tantalizing street food to exquisite fine dining. With Expedia, you can experience all of this and more, without sacrificing your budget.
Our flexible San Francisco Intl. to McGhee Tyson ticket options cater to your travel preferences, with incredible one-way fares from €134 and roundtrip prices from €310. Whether you're planning a short city break or a longer adventure, our dynamic pricing ensures that you find the best deals for your journey.
But the magic doesn't stop there. Expedia offers a range of partner services to enhance your trip. Rent a car at McGhee Tyson and explore and its surrounding areas at your own pace. Discover hidden gems off the beaten path, and create unforgettable memories. We also provide a handpicked selection of accommodations, from charming bed and breakfasts to luxury hotels, ensuring that you have a comfortable and memorable stay.
Planning your next great adventure is a breeze with Expedia. Our user-friendly platform, unbeatable prices, and round-the-clock customer support are designed to make your travel experience seamless and stress-free. So, why wait? Book your to travel arrangements today and embark on the journey of a lifetime in Knoxville.
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