
Popular airlines from McGhee Tyson Airport (TYS) to Chicago O'Hare Intl. Airport (ORD)
- Aer Lingus
Aer Lingus
- Lufthansa
Lufthansa
- British Airways
British Airways
- Turkish Airlines
Turkish Airlines
- American Airlines
American Airlines
- Air Serbia
Air Serbia
- Swiss International Air Lines
Swiss International Air Lines
- Plan, book, fly with confidence
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Cheap flights from Knoxville to Chicago (TYS-ORD)
Prices were available within the past 7 days and start at for one-way flights and €180 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Fri, 12 Sep - Mon, 15 Sep
TYS
Knoxville
ORD
Chicago
€180 Return, found 1 day ago
€180
Return
found 1 day ago

Fri, 12 Sep - Mon, 15 Sep
TYS
Knoxville
ORD
Chicago
€189 Return, found 1 day ago
€189
Return
found 1 day ago

Fri, 22 Aug - Mon, 25 Aug
TYS
Knoxville
ORD
Chicago
€193 Return, found 2 days ago
€193
Return
found 2 days ago

Fri, 12 Sep - Mon, 15 Sep
TYS
Knoxville
ORD
Chicago
€197 Return, found 1 day ago
€197
Return
found 1 day ago

Fri, 22 Aug - Mon, 25 Aug
TYS
Knoxville
ORD
Chicago
€202 Return, found 2 days ago
€202
Return
found 2 days ago

Fri, 12 Sep - Mon, 15 Sep
TYS
Knoxville
ORD
Chicago
€210 Return, found 1 day ago
€210
Return
found 1 day ago

Fri, 22 Aug - Mon, 25 Aug
TYS
Knoxville
ORD
Chicago
€210 Return, found 2 days ago
€210
Return
found 2 days ago

Fri, 12 Sep - Mon, 15 Sep
TYS
Knoxville
ORD
Chicago
€215 Return, found 1 day ago
€215
Return
found 1 day ago

Fri, 12 Sep - Mon, 15 Sep
TYS
Knoxville
ORD
Chicago
€218 Return, found 1 day ago
€218
Return
found 1 day ago

Fri, 12 Sep - Mon, 15 Sep
TYS
Knoxville
ORD
Chicago
€219 Return, found 1 day ago
€219
Return
found 1 day ago

Fri, 12 Sep - Mon, 15 Sep
TYS
Knoxville
ORD
Chicago
€219 Return, found 1 day ago
€219
Return
found 1 day ago

Fri, 12 Sep - Mon, 15 Sep
TYS
Knoxville
ORD
Chicago
€223 Return, found 1 day ago
€223
Return
found 1 day ago

Fri, 12 Sep - Mon, 15 Sep
TYS
Knoxville
ORD
Chicago
€228 Return, found 1 day ago
€228
Return
found 1 day ago

Fri, 12 Sep - Mon, 15 Sep
TYS
Knoxville
ORD
Chicago
€232 Return, found 1 day ago
€232
Return
found 1 day ago

Fri, 19 Sep - Mon, 22 Sep
TYS
Knoxville
ORD
Chicago
€232 Return, found 1 hour ago
€232
Return
found 1 hour ago

Fri, 12 Sep - Mon, 15 Sep
TYS
Knoxville
ORD
Chicago
€235 Return, found 1 day ago
€235
Return
found 1 day ago

Fri, 22 Aug - Mon, 25 Aug
TYS
Knoxville
ORD
Chicago
€236 Return, found 2 days ago
€236
Return
found 2 days ago

Fri, 12 Sep - Mon, 15 Sep
TYS
Knoxville
ORD
Chicago
€240 Return, found 1 day ago
€240
Return
found 1 day ago

Fri, 12 Sep - Mon, 15 Sep
TYS
Knoxville
ORD
Chicago
€244 Return, found 1 day ago
€244
Return
found 1 day ago

Fri, 12 Sep - Mon, 15 Sep
TYS
Knoxville
ORD
Chicago
€244 Return, found 1 day ago
€244
Return
found 1 day ago
Find the cheapest month to fly from Knoxville (TYS) to Chicago (ORD)
September is typically the cheapest month to fly
From €129 - €338 per traveller.
Graph displaying average flight prices per month
Origin airport | McGhee Tyson |
Destination airport | O'Hare Intl. |
Return price | €179 |
Distance | 760 km |
Perfect flights from Knoxville to Chicago
Embark on an unforgettable journey without breaking the bank with Expedia's incredible deals on cheap flights from Knoxville to Chicago. Whether you're aching for a romantic escape with your partner, craving an adventurous solo expedition, or yearning to immerse yourself in the local history and culture, we've got you covered.
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Our flexible McGhee Tyson to O'Hare Intl. ticket options cater to your travel preferences, with incredible one-way fares and roundtrip prices from €180. Whether you're planning a short city break or a longer adventure, our dynamic pricing ensures that you find the best deals for your journey.
But the magic doesn't stop there. Expedia offers a range of partner services to enhance your trip. Rent a car at O'Hare Intl. and explore Chicago and its surrounding areas at your own pace. Discover hidden gems off the beaten path, and create unforgettable memories. We also provide a handpicked selection of accommodations, from charming bed and breakfasts to luxury hotels, ensuring that you have a comfortable and memorable stay.
Planning your next great adventure is a breeze with Expedia. Our user-friendly platform, unbeatable prices, and round-the-clock customer support are designed to make your travel experience seamless and stress-free. So, why wait? Book your TYS to ORD travel arrangements today and embark on the journey of a lifetime in Chicago.
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Top Routes from Knoxville
Top Routes to Chicago
- Newark Liberty Intl. Airport to Chicago (EWR - ORD)
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- New York to Chicago (JFK - ORD)
- Dublin to Chicago (DUB - ORD)
- Shannon to Chicago (SNN - ORD)
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- Flights from New York (JFK) to Chicago (ORD)
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