
Popular airlines from McGhee Tyson Airport (TYS) to Chicago O'Hare Intl. Airport (ORD)
- Delta
Delta
- American Airlines
American Airlines
- United
United
- Frontier Airlines
Frontier Airlines
- Southwest Airlines
Southwest Airlines
- Be in the knowGet alerts if flight prices drop or rise*
- Book smarterSave up to 15% on select hotels after you book a flight*
Cheap flights from Knoxville to Chicago (TYS-ORD)
Prices were available within the past 7 days and start at €112 for one-way flights and €163 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Thu, 8 Jan - Sun, 11 Jan
TYS
Knoxville
ORD
Chicago
€163 Return, found 16 hours ago
€163
Return
found 16 hours ago

Thu, 8 Jan - Sun, 11 Jan
TYS
Knoxville
ORD
Chicago
€194 Return, found 16 hours ago
€194
Return
found 16 hours ago

Thu, 8 Jan - Sun, 11 Jan
TYS
Knoxville
ORD
Chicago
€202 Return, found 16 hours ago
€202
Return
found 16 hours ago

Thu, 8 Jan - Sun, 11 Jan
TYS
Knoxville
ORD
Chicago
€203 Return, found 16 hours ago
€203
Return
found 16 hours ago

Thu, 8 Jan - Sun, 11 Jan
TYS
Knoxville
ORD
Chicago
€216 Return, found 16 hours ago
€216
Return
found 16 hours ago

Thu, 8 Jan - Sun, 11 Jan
TYS
Knoxville
ORD
Chicago
€219 Return, found 16 hours ago
€219
Return
found 16 hours ago

Thu, 8 Jan - Sun, 11 Jan
TYS
Knoxville
ORD
Chicago
€228 Return, found 16 hours ago
€228
Return
found 16 hours ago

Thu, 8 Jan - Sun, 11 Jan
TYS
Knoxville
ORD
Chicago
€231 Return, found 16 hours ago
€231
Return
found 16 hours ago

Sat, 17 Jan - Sun, 18 Jan
TYS
Knoxville
ORD
Chicago
€233 Return, found 5 days ago
€233
Return
found 5 days ago

Thu, 8 Jan - Sun, 11 Jan
TYS
Knoxville
ORD
Chicago
€239 Return, found 16 hours ago
€239
Return
found 16 hours ago
Find the cheapest month to fly from Knoxville (TYS) to Chicago (ORD)
January is typically the cheapest month to fly
From €138 - €345 per traveller.
Origin airport | McGhee Tyson |
|---|---|
Destination airport | O'Hare Intl. |
Airlines serving | American Airlines, Delta, United |
Return price | €163 |
Distance | 760 km |
Average flight time | 1 hour 1 min |
Perfect flights from Knoxville to Chicago
Embark on an unforgettable journey without breaking the bank with Expedia's incredible deals on cheap flights from Knoxville to Chicago. Whether you're aching for a romantic escape with your partner, craving an adventurous solo expedition, or yearning to immerse yourself in the local history and culture, we've got you covered.
Picture yourself strolling through the streets of , surrounded by breathtaking architecture and absorbing the vibrant atmosphere of this captivating city. Indulge in the mouth-watering local specialties, from tantalizing street food to exquisite fine dining. With Expedia, you can experience all of this and more, without sacrificing your budget.
Our flexible McGhee Tyson to O'Hare Intl. ticket options cater to your travel preferences, with incredible one-way fares from €112 and roundtrip prices from €163. Whether you're planning a short city break or a longer adventure, our dynamic pricing ensures that you find the best deals for your journey.
But the magic doesn't stop there. Expedia offers a range of partner services to enhance your trip. Rent a car at O'Hare Intl. and explore and its surrounding areas at your own pace. Discover hidden gems off the beaten path, and create unforgettable memories. We also provide a handpicked selection of accommodations, from charming bed and breakfasts to luxury hotels, ensuring that you have a comfortable and memorable stay.
Planning your next great adventure is a breeze with Expedia. Our user-friendly platform, unbeatable prices, and round-the-clock customer support are designed to make your travel experience seamless and stress-free. So, why wait? Book your to travel arrangements today and embark on the journey of a lifetime in Chicago.
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Top Routes from Knoxville
Top Routes to Chicago
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- Flights from New York (JFK) to Chicago (ORD)
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