Louisville Hotel Guide - 21c Museum Hotel hotels in Louisville, United States of America.

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Check prices for these dates

Tonight
21 Apr - 22 Apr
Tomorrow
22 Apr - 23 Apr
This weekend
24 Apr - 26 Apr
Next weekend
1 May - 3 May

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Our top choices for 21c Museum Hotel hotels

Terrace/patio

Homewood Suites by Hilton Louisville Downtown, KY

Homewood Suites by Hilton Louisville Downtown, KY
3.0 star property
Downtown Louisville, 0.1 km from 21c Museum Hotel
9.4 out of 10, Exceptional, (1,012 reviews)
"Perfect place to access all that Louisville has to offer. Clean, comfortable, quiet and a great staff always eager to help"
United States
Bill
The price is €138
includes taxes & fees
11 May - 12 May
Homewood Suites by Hilton Louisville Downtown, KY
Lobby

The Grady

The Grady
4.0 star property
Downtown Louisville, 0.1 km from 21c Museum Hotel
9.4 out of 10, Exceptional, (1,008 reviews)
"Such an amazing hotel...restaurant is delicious! "
United States
Craig
The price is €186
includes taxes & fees
26 Apr - 27 Apr
The Grady
Front of property

21c Museum Hotel Louisville

21c Museum Hotel Louisville
4.5 star property
Downtown Louisville, < 0.1 km from 21c Museum Hotel
9.4 out of 10, Exceptional, (1,004 reviews)
"Nice room and close to all the distilleries. Great restaurant on site as well!"
United States
Brent
The price is €198
includes taxes & fees
17 May - 18 May
21c Museum Hotel Louisville
Terrace/patio

Hotel Distil, Autograph Collection

Hotel Distil, Autograph Collection
4.0 star property
Downtown Louisville, 0.8 km from 21c Museum Hotel
9.6 out of 10, Exceptional, (461 reviews)
"Great hotel & location"
United States
Ana
The price is €202
includes taxes & fees
10 May - 11 May
Hotel Distil, Autograph Collection
Lobby

The Brown Hotel

The Brown Hotel
4.5 star property
Downtown Louisville, 1.2 km from 21c Museum Hotel
9.4 out of 10, Exceptional, (1,193 reviews)
"Awesome staff, beautiful hotel, great food and bar"
United States
Jason
The price is €163
includes taxes & fees
4 May - 5 May
The Brown Hotel
Interior entrance

Market Street Inn

Market Street Inn
3.5 star property
2.1 km from 21c Museum Hotel
9.8 out of 10, Exceptional, (121 reviews)
"The staff and breakfast were all exceptional. "
United States
Roberta
The price is €178
includes taxes & fees
27 Apr - 28 Apr
Market Street Inn
Interior entrance

Louisville Bourbon Inn

Louisville Bourbon Inn
5.0 star property
Old Louisville, 2.8 km from 21c Museum Hotel
10.0 out of 10, Exceptional, (22 reviews)
"Great breakfast. Frittata, French toast, eggs, bacon, sausage, grapes, toast, biscuits and gravy - all were excellent. "
United States
Gaven
The price is €305
includes taxes & fees
22 Apr - 23 Apr
Louisville Bourbon Inn
Dining

Cambria Hotel Louisville Downtown-Whiskey Row

Cambria Hotel Louisville Downtown-Whiskey Row
3.0 star property
Downtown Louisville, 1.2 km from 21c Museum Hotel
9.4 out of 10, Exceptional, (1,006 reviews)
"Clean room, friendly staff, nice bar"
United States
Jack
The price is €130
includes taxes & fees
22 May - 23 May
Cambria Hotel Louisville Downtown-Whiskey Row
Property amenity

Towneplace Suites By Marriott Louisville Downtown

Towneplace Suites By Marriott Louisville Downtown
3.0 star property
Downtown Louisville, 0.3 km from 21c Museum Hotel
9.2 out of 10, Wonderful, (591 reviews)
"Always enjoy our stays here, staff are so friendly and helpful!"
United States
Debra
The price is €139
includes taxes & fees
21 May - 22 May
Towneplace Suites By Marriott Louisville Downtown
Terrace/patio

Hotel Bourré Bonne Louisville, Curio Collection by Hilton

Hotel Bourré Bonne Louisville, Curio Collection by Hilton
4.0 star property
Downtown Louisville, 0.8 km from 21c Museum Hotel
9.4 out of 10, Exceptional, (96 reviews)
"Very friendly and helpful staff. Hotel is clean and wonderful. "
United States
Emily
The price is €220
includes taxes & fees
17 May - 18 May
Hotel Bourré Bonne Louisville, Curio Collection by Hilton
4 restaurants, breakfast, lunch, dinner served; American cuisine

Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham
4.0 star property
Downtown Louisville, 0.5 km from 21c Museum Hotel
9.0 out of 10, Wonderful, (4,172 reviews)
"The location is great. Close to lots of great spots!"
United States
Robert
The price is €204
includes taxes & fees
22 Apr - 23 Apr
Galt House Hotel Trademark Collection by Wyndham
Interior entrance

Moxy Louisville Downtown

Moxy Louisville Downtown
3.5 star property
Downtown Louisville, 0.9 km from 21c Museum Hotel
9.2 out of 10, Wonderful, (740 reviews)
"Such a cool place! Staff was wonderful! Will definitely stay here again!"
United States
Judy
The price is €104
includes taxes & fees
10 May - 11 May
Moxy Louisville Downtown
Lounge

Stellar Suites

Stellar Suites
4.5 star property
East Market District, 2.2 km from 21c Museum Hotel
9.6 out of 10, Exceptional, (132 reviews)
"Easy check in and check out process and very convenient location."
United States
Richard
The price is €160
includes taxes & fees
22 Apr - 23 Apr
Stellar Suites
Front of property

DuPont Mansion Bed & Breakfast

DuPont Mansion Bed & Breakfast
3.0 star property
Old Louisville, 2.8 km from 21c Museum Hotel
9.6 out of 10, Exceptional, (115 reviews)
"Breakfast was wonderful, great place to stay!"
United States
Janie
The price is €142
includes taxes & fees
26 Apr - 27 Apr
DuPont Mansion Bed & Breakfast
2 restaurants, breakfast served

Tempo By Hilton Louisville Downtown Nulu

Tempo By Hilton Louisville Downtown Nulu
3.5 star property
Phoenix Hill, 2 km from 21c Museum Hotel
9.4 out of 10, Exceptional, (993 reviews)
"Nice place with friendly staff."
United States
Steve
The price is €137
includes taxes & fees
10 May - 11 May
Tempo By Hilton Louisville Downtown Nulu
Reception

Embassy Suites Louisville Downtown

Embassy Suites Louisville Downtown
4.0 star property
Downtown Louisville, 0.8 km from 21c Museum Hotel
9.0 out of 10, Wonderful, (1,201 reviews)
"Great location "
United States
Robert
The price is €164
includes taxes & fees
10 May - 11 May
Embassy Suites Louisville Downtown
Lobby sitting area

Holiday Inn Express & Suites Louisville Downtown by IHG

Holiday Inn Express & Suites Louisville Downtown by IHG
2.5 star property
Downtown Louisville, 0.3 km from 21c Museum Hotel
8.8 out of 10, Excellent, (1,741 reviews)
"Property was great and affordable"
United States
Jessica
The price is €139
includes taxes & fees
10 May - 11 May
Holiday Inn Express & Suites Louisville Downtown by IHG
Terrace/patio

Hotel Genevieve part of JdV by Hyatt

Hotel Genevieve part of JdV by Hyatt
4.0 star property
East Market District, 2 km from 21c Museum Hotel
9.2 out of 10, Wonderful, (1,079 reviews)
"What a great unique hotel. Staff was fantastic and room was spotless. Only issue was the lounge/bar was closed on the only day we were there. We will definitely be back. "
United States
Matthew
The price is €145
includes taxes & fees
11 May - 12 May
Hotel Genevieve part of JdV by Hyatt
Lobby lounge

AC Hotel Louisville Downtown

AC Hotel Louisville Downtown
3.5 star property
East Market District, 2 km from 21c Museum Hotel
9.2 out of 10, Wonderful, (650 reviews)
"Great location, friendly staff, very clean and smelled good. Breakfast was really good too! Would stay here again. "
United States
Holly
The price is €120
includes taxes & fees
10 May - 11 May
AC Hotel Louisville Downtown
Restaurant

Aloft Louisville Downtown

Aloft Louisville Downtown
3.0 star property
Downtown Louisville, 0.9 km from 21c Museum Hotel
9.0 out of 10, Wonderful, (1,005 reviews)
"Staff always, clean rooms, easy access to lots of downtown fun!"
United States
Stephanie
The price is €140
includes taxes & fees
18 May - 19 May
Aloft Louisville Downtown
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Compare popular hotels close to 21c Museum Hotel

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
Interior entrance
Louisville Bourbon Inn
5.0 star property
10.0
Exceptional
22 reviews
View
Interior entrance
Market Street Inn
3.5 star property
9.8
Exceptional
121 reviews
View
Lobby
The Grady
4.0 star property
9.4
Exceptional
1,008 reviews
View
Terrace/patio
Hotel Distil, Autograph Collection
4.0 star property
9.6
Exceptional
461 reviews
View
Terrace/patio
Homewood Suites by Hilton Louisville Downtown, KY
3.0 star property
9.4
Exceptional
1,012 reviews
View

Top 21c Museum Hotel Hotel Reviews

Holiday Inn Express & Suites Louisville Downtown by IHG

Holiday Inn Express & Suites Louisville Downtown by IHG

8/10 Good
"A very clean hotel."
Miguel 3-night trip
Posted 2 hours ago
Holiday Inn Express & Suites Louisville Downtown by IHG

Hotels near other 21c Museum Hotel attractions

Louisville Science Center

3.9/5 (6 reviews)
Science is all around us, inescapable. Understand important elements of our world with a visit to this science center for all ages.
See properties

Kentucky Center for the Performing Arts

4.4/5 (49 reviews)
Enjoy a pleasant night at the opera or attend a concert, live dance or stage production at this glass-fronted venue in downtown Louisville.
See properties

Frequently asked questions

What's the area like around 21c Museum Hotel?
21c Museum Hotel is located in a family-friendly area of Louisville known for its stunning river views and great live music scene. If you're looking for a convenient place to stay, take a look at the 267 hotels and other accommodation options you'll find within a mile.
What's the best hotel to stay near 21c Museum Hotel?
Adjacent to 21c Museum Hotel, Galt House Hotel Trademark Collection by Wyndham is one of the top choices for your stay based on our traveller data, and this hotel offers a full-service spa and 4 restaurants. Other good choices within a short distance include Omni Louisville Hotel and Homewood Suites by Hilton Louisville Downtown, KY.
How many hotels are there near 21c Museum Hotel?
Expedia has 267 hotels and other accommodation options within a mile from 21c Museum Hotel.
If I need to cancel the hotel reservation for my stay near 21c Museum Hotel, will I receive a refund?
Yes, you'll find most room reservations are refundable if you cancel prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before your check-in date. If you have a non-refundable reservation, you might be able to still cancel and receive a refund within 24 hours of your booking. Add your dates and click on "Search", then use the "fully refundable" filter to get the best deals available near 21c Museum Hotel.
What can I see and do near 21c Museum Hotel?
You might want to spend some time browsing the exhibits at Louisville Science Center, Muhammad Ali Center or Louisville Slugger Museum. Explore landmarks like Belle of Louisville, Whiskey Row and Big Four Bridge. You can watch performances at Louisville Palace, Derby Dinner Playhouse and Headliners Music Hall if you're interested in local theatre.