Louisville Hotel Guide - 21c Museum Hotel hotels in Louisville, United States of America.

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Check prices for these dates

Tonight
10 Nov - 11 Nov
Tomorrow
11 Nov - 12 Nov
This weekend
13 Nov - 15 Nov
Next weekend
20 Nov - 22 Nov

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Our top choices for 21c Museum Hotel hotels

A grand staircase with a wooden handrail and carpeted steps, leading to an upper floor.

1. Louisville Bourbon Inn

Louisville Bourbon Inn
5.0 star property
Old Louisville, 2.8 km from 21c Museum Hotel
10.0 out of 10, Exceptional, (25 reviews)
"Absolutely the best B&B we have ever stayed with."
United States
Roy
The price is €321
includes taxes & fees
24 Nov - 25 Nov
Louisville Bourbon Inn
A wooden staircase with a balustrade leading to a landing.

2. Market Street Inn

Market Street Inn
3.5 star property
2.1 km from 21c Museum Hotel
9.8 out of 10, Exceptional, (127 reviews)
"Such a lovely stay at the Market Street Inn. A very charming, comfortable and feels like home kind of place. Carol and Steve are just the kindest owners. They were responsive and accommodating and always available if needed. We also loved meeting Lisa, who made breakfast each morning and took care of any housekeeping needs. We felt like we were treated as family and not just guests. The area and location is perfect, SUCH a cute little town. Plenty of restaurants, shops and entertainment within...
United States
Ryan
The price is €223
includes taxes & fees
17 Nov - 18 Nov
Market Street Inn
A grand hotel lobby with ornate ceiling designs, a central staircase, and a dining area.

3. The Brown Hotel

The Brown Hotel
4.5 star property
Downtown Louisville, 1.2 km from 21c Museum Hotel
9.4 out of 10, Exceptional, (1,471 reviews)
"Beautiful hotel!"
United States
Brianne
The price is €109
includes taxes & fees
24 Nov - 25 Nov
The Brown Hotel
An indoor dining area with tables set for guests, surrounded by potted plants and hanging lights.

4. Hotel Distil, Autograph Collection

Hotel Distil, Autograph Collection
4.0 star property
Downtown Louisville, 0.8 km from 21c Museum Hotel
9.6 out of 10, Exceptional, (519 reviews)
"Excellent location and room!"
United States
Athina
The price is €213
includes taxes & fees
22 Nov - 23 Nov
Hotel Distil, Autograph Collection
A spacious lobby with a high ceiling, a central chandelier, and seating areas with tables and chairs.

5. Omni Louisville Hotel

Omni Louisville Hotel
4.0 star property
Downtown Louisville, 0.8 km from 21c Museum Hotel
9.4 out of 10, Exceptional, (2,230 reviews)
"Very very nice property clean well taken care of and great staff would stay again"
United States
James
The price is €186
includes taxes & fees
24 Nov - 25 Nov
Omni Louisville Hotel
A spacious indoor patio with a fire pit, wooden pergola, and comfortable seating areas.

6. Homewood Suites by Hilton Louisville Downtown, KY

Homewood Suites by Hilton Louisville Downtown, KY
3.0 star property
Downtown Louisville, 0.1 km from 21c Museum Hotel
9.4 out of 10, Exceptional, (1,003 reviews)
"Nice hotel"
United States
Jeanette
The price is €120
includes taxes & fees
28 Nov - 29 Nov
Homewood Suites by Hilton Louisville Downtown, KY
A modern interior with a fireplace, bookshelves, a green sofa, and leather chairs.

7. The Grady

The Grady
4.0 star property
Downtown Louisville, 0.1 km from 21c Museum Hotel
9.4 out of 10, Exceptional, (1,011 reviews)
"Our stay at The Grady was exceptional and we will definitely be back to stay again soon!!"
United States
Greg
The price is €150
includes taxes & fees
22 Nov - 23 Nov
The Grady
A historic building with a grand entrance, steps leading up to the door, and a sign indicating it is a bed and breakfast.

8. DuPont Mansion Bed & Breakfast

DuPont Mansion Bed & Breakfast
4.0 star property
Old Louisville, 2.8 km from 21c Museum Hotel
9.6 out of 10, Exceptional, (151 reviews)
"Great staff, clean rooms, amazing historic vibe, and yummy breakfast!"
United States
Chris
The price is €190
includes taxes & fees
11 Nov - 12 Nov
DuPont Mansion Bed & Breakfast
An outdoor terrace with tables and chairs, large windows, and a view of the city skyline at sunset.

9. Tempo By Hilton Louisville Downtown Nulu

Tempo By Hilton Louisville Downtown Nulu
3.5 star property
Phoenix Hill, 2 km from 21c Museum Hotel
9.4 out of 10, Exceptional, (1,156 reviews)
"Great stay!"
United States
Addison
The price is €107
includes taxes & fees
25 Nov - 26 Nov
Tempo By Hilton Louisville Downtown Nulu
An outdoor seating area with sofas and tables, a fire feature, and a clock tower in the background.

10. Hotel Bourré Bonne Louisville, Curio Collection by Hilton

Hotel Bourré Bonne Louisville, Curio Collection by Hilton
4.0 star property
Downtown Louisville, 0.8 km from 21c Museum Hotel
9.4 out of 10, Exceptional, (178 reviews)
"Very good breakfast in hotel lobby restaurant. Extremely nice servers. Reasonably priced."
United States
Paul
The price is €146
includes taxes & fees
26 Nov - 27 Nov
Hotel Bourré Bonne Louisville, Curio Collection by Hilton
A cozy room with a geometric-patterned ceiling, a sofa, and a chair.

11. 21c Museum Hotel Louisville

21c Museum Hotel Louisville
4.5 star property
Downtown Louisville, < 0.1 km from 21c Museum Hotel
9.4 out of 10, Exceptional, (1,003 reviews)
"Nice modern rooms and excellent cocktails in the bar."
United States
Erick
The price is €165
includes taxes & fees
6 Dec - 7 Dec
21c Museum Hotel Louisville
A covered patio with a stone wall, a glass table, and a bench.

12. Central Park Bed & Breakfast

Central Park Bed & Breakfast
3.5 star property
Old Louisville, 2.9 km from 21c Museum Hotel
9.4 out of 10, Exceptional, (101 reviews)
"Amazing stay and hospitality. Will stay again"
United States
Stephen
The price is €177
includes taxes & fees
18 Nov - 19 Nov
Central Park Bed & Breakfast
A modern hotel lobby with a reception desk, seating area, and a staircase leading to the upper floor.

13. Stellar Suites

Stellar Suites
4.5 star property
East Market District, 2.2 km from 21c Museum Hotel
9.4 out of 10, Exceptional, (158 reviews)
"Location was great near meant restaurants and nightspots"
United States
Kevin
The price is €160
includes taxes & fees
18 Nov - 19 Nov
Stellar Suites
A modern bar area with a circular bar, multiple seating options, and a large screen.

14. Cambria Hotel Louisville Downtown-Whiskey Row

Cambria Hotel Louisville Downtown-Whiskey Row
3.0 star property
Downtown Louisville, 1.2 km from 21c Museum Hotel
9.2 out of 10, Wonderful, (1,023 reviews)
"Clean and bathrooms are nice I will be staying again."
United States
Trista
The price is €100
includes taxes & fees
3 Dec - 4 Dec
Cambria Hotel Louisville Downtown-Whiskey Row
An outdoor seating area with wicker furniture and a fire pit.

15. Towneplace Suites By Marriott Louisville Downtown

Towneplace Suites By Marriott Louisville Downtown
3.0 star property
Downtown Louisville, 0.3 km from 21c Museum Hotel
9.2 out of 10, Wonderful, (830 reviews)
"Nice stay, bed was comfortable"
United States
Brandi
The price is €102
includes taxes & fees
7 Dec - 8 Dec
Towneplace Suites By Marriott Louisville Downtown
An indoor dining area with wooden tables and chairs, a bar area, and a view of the street outside.

16. Aloft by Marriott Louisville Downtown

Aloft by Marriott Louisville Downtown
3.0 star property
Downtown Louisville, 0.9 km from 21c Museum Hotel
9.2 out of 10, Wonderful, (1,002 reviews)
"Great clean hotel awesome staff."
United States
Anthony
The price is €120
includes taxes & fees
23 Nov - 24 Nov
Aloft by Marriott Louisville Downtown
A bar area with a neon 'CHECK IN' sign, a variety of liquor bottles, and a modern seating arrangement.

17. Moxy Louisville Downtown

Moxy Louisville Downtown
3.5 star property
Downtown Louisville, 0.9 km from 21c Museum Hotel
9.2 out of 10, Wonderful, (862 reviews)
"Hotel was super clean and staff were friendly in a great location"
United States
Sheree
The price is €119
includes taxes & fees
25 Nov - 26 Nov
Moxy Louisville Downtown
An outdoor dining area with a long table and wicker chairs, overhead lighting, and a view of the city.

18. Hotel Genevieve part of JdV by Hyatt

Hotel Genevieve part of JdV by Hyatt
4.0 star property
East Market District, 2 km from 21c Museum Hotel
9.2 out of 10, Wonderful, (1,088 reviews)
"We’ve stayed here a number of times and we love it. Right in the middle of NuLu, it’s the perfect spot."
United States
Jesse
The price is €150
includes taxes & fees
15 Nov - 16 Nov
Hotel Genevieve part of JdV by Hyatt
A modern bar area with a marble countertop, seating, and a central bar stocked with bottles.

19. AC Hotel Louisville Downtown

AC Hotel Louisville Downtown
3.5 star property
East Market District, 2 km from 21c Museum Hotel
9.2 out of 10, Wonderful, (733 reviews)
"Great location, helpful staff, and nice clean rooms,"
United States
Kevin
The price is €150
includes taxes & fees
22 Nov - 23 Nov
AC Hotel Louisville Downtown
A modern interior with large windows offering a city view, a circular light fixture, and leather seating.

20. Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham
4.0 star property
Downtown Louisville, 0.5 km from 21c Museum Hotel
9.0 out of 10, Wonderful, (4,486 reviews)
"Great place to stay!!!"
United States
Shun
The price is €143
includes taxes & fees
24 Nov - 25 Nov
Galt House Hotel Trademark Collection by Wyndham
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Compare popular hotels close to 21c Museum Hotel

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
A grand staircase with a wooden handrail and carpeted steps, leading to an upper floor.
Louisville Bourbon Inn
5.0 star property
10.0
Exceptional
25 reviews
View
A wooden staircase with a balustrade leading to a landing.
Market Street Inn
3.5 star property
9.8
Exceptional
127 reviews
View
A grand hotel lobby with ornate ceiling designs, a central staircase, and a dining area.
The Brown Hotel
4.5 star property
9.4
Exceptional
1,471 reviews
View
An indoor dining area with tables set for guests, surrounded by potted plants and hanging lights.
Hotel Distil, Autograph Collection
4.0 star property
9.6
Exceptional
519 reviews
View
A spacious lobby with a high ceiling, a central chandelier, and seating areas with tables and chairs.
Omni Louisville Hotel
4.0 star property
9.4
Exceptional
2,230 reviews
View

Other attractions near 21c Museum Hotel

A historic building with ornate architecture, including columns and decorative moldings.

Louisville Science Center

7.8/10 (6 reviews)
Science is all around us, inescapable. Understand important elements of our world with a visit to this science center for all ages.
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Frequently Asked Questions

What's the area like around 21c Museum Hotel?

21c Museum Hotel is located in a family-friendly area of Louisville known for its stunning river views and great live music scene. If you're looking for a convenient place to stay, take a look at the 292 hotels and other accommodation options you'll find within a mile.

What's the best hotel to stay near 21c Museum Hotel?

Adjacent to 21c Museum Hotel, Galt House Hotel Trademark Collection by Wyndham is one of the top choices for your stay based on our traveller data, and this hotel offers a full-service spa and 4 restaurants. Other good choices within a short distance include Holiday Inn Express & Suites Louisville Downtown by IHG and Omni Louisville Hotel.

How many hotels are there near 21c Museum Hotel?

Expedia has 292 hotels and other accommodation options within a mile from 21c Museum Hotel.

If I need to cancel the hotel reservation for my stay near 21c Museum Hotel, will I receive a refund?

Yes, you'll find most room reservations are refundable if you cancel prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before your check-in date. If you have a non-refundable reservation, you might be able to still cancel and receive a refund within 24 hours of your booking. Add your dates and click on "Search", then use the "fully refundable" filter to get the best deals available near 21c Museum Hotel.

What can I see and do near 21c Museum Hotel?

You might want to spend some time browsing the exhibits at Muhammad Ali Center, Louisville Slugger Museum or Frazier International History Museum. Explore landmarks like Belle of Louisville, Whiskey Row and Big Four Bridge. You can watch performances at Louisville Palace, Derby Dinner Playhouse and Headliners Music Hall if you're interested in local theatre.