A modern glass building with a curved facade and a sign reading "The Kentucky Center".

4 Star Hotels in Southern Indiana, United States of America

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Check availability on Southern Indiana 4 Star Hotels

Tonight
28 Aug - 29 Aug
Tomorrow
29 Aug - 30 Aug
This weekend
28 Aug - 30 Aug
Next weekend
4 Sept - 6 Sept

Our top choices for Southern Indiana 4-star hotels

A modern interior with large windows offering a city view, a circular light fixture, and leather seating.
A balcony with a view of a river, a bridge, and a cityscape.
A modern bar with a long counter, multiple shelves of liquor bottles, and cushioned bar stools.
A spacious room with a large dining table, comfortable seating, a sofa, and a view of a bridge.

1. Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham
Downtown Louisville
United States
Jacob
€144
includes taxes & fees
8 Sept - 9 Sept
Galt House Hotel Trademark Collection by Wyndham
A spacious lobby with a high ceiling, a central chandelier, and seating areas with tables and chairs.
A lobby with a marble floor, a reception desk, and a large chandelier.
A rooftop bar with outdoor seating, including sofas and chairs, and a bar area with a television screen.
A modern building entrance with a glass facade, wooden ceiling, and illuminated fixtures.

2. Omni Louisville Hotel

Omni Louisville Hotel
Downtown Louisville
United States
Kara
€201
includes taxes & fees
30 Aug - 31 Aug
Omni Louisville Hotel
A spacious lobby with a central escalator, comfortable seating areas, and modern lighting fixtures.
An outdoor seating area with wicker furniture, wooden tables, and large lamps.
A modern lobby with a central seating area, an escalator, and a staircase.
A modern hotel exterior with outdoor seating, a glass canopy, and a visible sign for the Hyatt Regency.

3. Hyatt Regency Louisville

Hyatt Regency Louisville
Downtown Louisville
United States
Arnetta
€143
includes taxes & fees
6 Sept - 7 Sept
Hyatt Regency Louisville
A grand lobby with ornate columns, plush seating, and a chandelier.
A grand dining area with ornate ceiling, chandeliers, and a bar area with a sign reading "Cigar Bar".
A grand lobby with ornate ceiling and chandeliers, a large vase, and a seating area with multiple sofas and armchairs.
A grand lobby with ornate ceiling, multiple seating areas, and a staircase.

4. The Brown Hotel

The Brown Hotel
Downtown Louisville
United States
Rachel
€151
includes taxes & fees
4 Sept - 5 Sept
The Brown Hotel
A spacious lobby with a blue sofa, a wooden coffee table, and a chandelier.
A modern hotel room with a living area, a dining area, and a bedroom.
An indoor swimming pool with clear water, surrounded by white marble walls and columns, and furnished with lounge chairs and tables.
A hotel dining area with long tables, booths, and a bar.

5. Embassy Suites Louisville Downtown

Embassy Suites Louisville Downtown
Downtown Louisville
United States
Spencer
€130
includes taxes & fees
5 Sept - 6 Sept
Embassy Suites Louisville Downtown
A classical gold statue in front of a multi-story building with large windows and a brick facade.
A cozy room with a geometric-patterned ceiling, a sofa, and a chair.
A cozy room with wooden walls, a table with a lamp, and shelves displaying books and decorative items.
A steam fountain in a brick alleyway.

6. 21c Museum Hotel Louisville

21c Museum Hotel Louisville
Downtown Louisville
United States
Candice
€185
includes taxes & fees
1 Sept - 2 Sept
21c Museum Hotel Louisville
A room with a checkered floor, leather armchairs, a sofa, and a small table with a glass. There are windows with arched tops and a view of buildings outside.
A yellow coffee shop counter with a menu board above, displaying various coffee and food items.
A bedroom with a bed, a chair, a TV, and a window with curtains.
A bar area with a wooden bar counter, two stools, a chandelier, and a mirror.

7. Hotel Genevieve part of JdV by Hyatt

Hotel Genevieve part of JdV by Hyatt
Downtown Louisville
United States
Rebekah
€136
includes taxes & fees
3 Sept - 4 Sept
Hotel Genevieve part of JdV by Hyatt
A modern interior with a fireplace, bookshelves, a green sofa, and leather chairs.
A building with a sign reading "THE GRADY" at the entrance.
A modern restaurant interior with a staircase, round tables, and a brick wall.
A multi-level interior with a staircase, bookshelves, and a prominent sign reading "THE GRADY".

8. The Grady

The Grady
Downtown Louisville
United States
Conswaila
€166
includes taxes & fees
30 Aug - 31 Aug
The Grady
A modern building with a restaurant on the ground floor, featuring large windows and outdoor seating.
A modern bar area with glass partitions, bar stools, and a variety of bottles.
A reception area with marble counters, modern pendant lighting, and potted orchids.
A spacious lobby with a bar area, seating arrangements, and a visible kitchen bar.

9. Louisville Marriott Downtown

Louisville Marriott Downtown
Downtown Louisville
United States
Lisa
€171
includes taxes & fees
4 Sept - 5 Sept
Louisville Marriott Downtown
An indoor dining area with tables set for guests, surrounded by potted plants and hanging lights.
A modern living room with a leather sectional sofa, a glass coffee table, and a view of the city skyline through large windows.
A multi-story hotel with a classic facade, large windows, and a modern glass building adjacent to it.
A bar with shelves of liquor bottles and a bartender preparing drinks.

10. Hotel Distil, Autograph Collection

Hotel Distil, Autograph Collection
Downtown Louisville
United States
Jasmine
€221
includes taxes & fees
7 Sept - 8 Sept
Hotel Distil, Autograph Collection
An outdoor seating area with sofas and tables, a fire feature, and a clock tower in the background.
A modern hotel room with a large bed, a city view, and a unique headboard design.
A modern lobby with a central reception desk, seating area, and a large abstract wall art piece.
A modern living room with a sofa, a coffee table, a side table with a plant, and a view of a building with a clock tower.

11. Hotel Bourré Bonne Louisville, Curio Collection by Hilton

Hotel Bourré Bonne Louisville, Curio Collection by Hilton
Downtown Louisville
United States
Kristen
€173
includes taxes & fees
7 Sept - 8 Sept
Hotel Bourré Bonne Louisville, Curio Collection by Hilton
A modern living room with a fireplace, a coffee table with books, a jar of cookies, and a plate of cookies.
A spacious lobby with a modern staircase, a round table with vases, and comfortable seating areas.
An outdoor pool area with lounge chairs, a fire pit, and a building with brick walls and windows.
A modern building with a prominent sculpture in front, large glass windows, and a brightly lit entrance.

12. DoubleTree by Hilton Evansville

DoubleTree by Hilton Evansville
Downtown Evansville
United States
Jennifer
€96
includes taxes & fees
13 Sept - 14 Sept
DoubleTree by Hilton Evansville
A historic hotel with ornate architecture, a grand entrance, and a red carpet leading to the doors.
A spacious living room with a fireplace, wooden paneling, a television, and a blue sofa.
A grand staircase with ornate railings and a marble floor, leading to a high-ceilinged lobby with decorative moldings and a chandelier.
A grand lobby with marble floors, a staircase, and a reception desk.

13. Seelbach Hilton Louisville Downtown

Seelbach Hilton Louisville Downtown
Downtown Louisville
United States
Jennifer
€153
includes taxes & fees
6 Sept - 7 Sept
Seelbach Hilton Louisville Downtown
A grand entrance with a staircase leading to a door, flanked by two lamp posts and a bench.
A marble countertop with a tray of colorful glassware, a bottle, and two glasses. A framed painting hangs above, and two lamps are on either side.
A long table set with white tablecloths, gold chargers, and clear glassware.
A grand hallway with a wooden floor, a staircase, a chandelier, and a large mirror.

14. The Pepin Mansion Historic B&B

The Pepin Mansion Historic B&B
New Albany
United States
Bonnie
€88
includes taxes & fees
31 Aug - 1 Sept
The Pepin Mansion Historic B&B
A modern hotel lobby with a reception desk, seating area, and a staircase leading to the upper floor.
A modern KFC building with large glass windows, a prominent sign, and a well-lit entrance area.
A modern, well-lit room with a large bed, a green sofa, a small round table, and a kitchen area in the background.
A modern interior with a green wall, black chairs, and a ceiling with exposed beams and lights.

15. Stellar Suites

Stellar Suites
Downtown Louisville
United States
Brad
€145
includes taxes & fees
1 Sept - 2 Sept
Stellar Suites
A rooftop pool area with multiple lounge chairs and umbrellas, surrounded by a high-rise building with balconies.
A gym with exercise equipment, mirrors, and a TV screen.
A modern kitchen with white cabinets, stainless steel appliances, and a dining area with a table and chairs.
A multi-story residential building with balconies, a brick facade, and large windows.

16. CozySuites at Nulu

CozySuites at Nulu
Downtown Louisville
United States
Roy
€179
includes taxes & fees
31 Aug - 1 Sept
CozySuites at Nulu
A modern hotel with a 'Stay Apt Suites' sign, featuring a brick facade, large windows, and a parking lot.
A reception desk with a dark wood finish, a sign reading "stay apt SUITES", and a telephone.

17. stayAPT Suites Louisville North-Clarksville

stayAPT Suites Louisville North-Clarksville
Clarksville
United States
Chauntel
€144
includes taxes & fees
29 Aug - 30 Aug
stayAPT Suites Louisville North-Clarksville
A modern lounge with leather sofas, a coffee table, and a view of a classical building.
A modern living room with a leather sofa, two coffee tables, and a chessboard. There are shelves with bottles and glasses, and a large window on the right.
A modern interior with a wooden dining table, leather sofas, and a bar area with shelves.
A narrow corridor with exposed brick walls, wooden flooring, and a seating area with tables and chairs.

18. The Reserve on Main

The Reserve on Main
Downtown Louisville
United States
De'Carlon
The Reserve on Main
A large, multi-story building with a prominent tower and multiple windows.
A large outdoor swimming pool with a Ferris wheel in the background.
A spacious living area with a large, ornate rug, a wooden bench, and a staircase with white balusters.
A cozy seating area with two leather armchairs and a small round table. A table lamp and a wine glass are on the table.

19. Bourbon Barrel Inn Bed & Breakfast

Bourbon Barrel Inn Bed & Breakfast
Old Louisville
United States
jonathan
Bourbon Barrel Inn Bed & Breakfast
A modern kitchen with wooden cabinets, a black microwave, and a stainless steel refrigerator.
A living room with a sofa, a coffee table, and a ceiling fan. There is a dining area with a table and chairs.
A two-story brick house with a garage, a front door, and a small front yard with a lawn and a few shrubs.
A kitchen with wooden cabinets, a refrigerator, a coffee maker, and a tiled backsplash.

20. Spacious 3 BR Ranch House W Patio Yard in a Quiet Suburb

Spacious 3 BR Ranch House W Patio Yard in a Quiet Suburb
Sellersburg
United States
Tammy
Spacious 3 BR Ranch House W Patio Yard in a Quiet Suburb
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Learn more about Southern Indiana

Find lots to see and do in Southern Indiana—live music, sports teams and sights from Patoka Lake Swimming Beach to Patoka Lake.

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A riverboat with multiple decks and passengers, docked near a bridge.

Top Southern Indiana Hotel Reviews

Frequently asked questions

What are the best 4-star hotels in Southern Indiana?
Based on reviews by our guests, Galt House Hotel Trademark Collection by Wyndham is among the best 4-star hotels in Southern Indiana. Situated in Louisville, it includes massage services and beauty services. Hyatt Regency Louisville is another sought-after option here. Also with a 4-star rating and offering premium bedding and designer toiletries, you're sure to have a comfortable stay.
How much does it cost to stay in a 4-star hotel in Southern Indiana?
To book a 4-star hotel in Southern Indiana that's within your budget, take advantage of Expedia's handy filters. Take a look at what's available during your preferred dates and use our pricing filter to set your limit. You can also sort your results by the most budget-friendly option first.
  • Search for the lowest price from €88
What's the difference between 5-star and 4-star hotels in Southern Indiana?
Give yourself the luxury treatment during your Southern Indiana escape by checking in to a 4-star hotel. As well as featuring upmarket surroundings, these properties are typically packed with amenities such as large beds, bathrobes and plenty more. A 5-star hotel will go the extra mile to make your stay an even more indulgent and memorable one. 24-hour concierge assistance, luxurious spas and world-class dining are a few of the exclusive services and conveniences you'll likely be able to enjoy.

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