4 Star Hotels in Southern Indiana, United States of America

    calendar shield illustration

    Change your mind

    Book hotels with free cancellation
    deals illustration

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in
    bed illustration

    Be picky

    Search almost a million properties worldwide

Check availability on Southern Indiana 4 Star Hotels

Top Southern Indiana 4 Star Hotels

Galt House Hotel Trademark Collection by Wyndham
4 restaurants, breakfast, lunch, dinner served; American cuisine

Galt House Hotel Trademark Collection by Wyndham

4.0 star property
8.8 out of 10, Excellent, (3522)
"Wonderful and fun place to stay "
The price is €129
includes taxes & fees
31 Aug - 1 Sept
Galt House Hotel Trademark Collection by Wyndham
Omni Louisville Hotel
Sauna, body treatments, aromatherapy, hot stone massages

Omni Louisville Hotel

4.0 star property
9.2 out of 10, Wonderful, (1556)
"Wonderful stay and close to restaurants and shops."
The price is €160
includes taxes & fees
29 Aug - 30 Aug
Omni Louisville Hotel
Embassy Suites Louisville Downtown
Dinner served

Embassy Suites Louisville Downtown

4.0 star property
9.0 out of 10, Wonderful, (1000)
"Great place"
The price is €127
includes taxes & fees
24 Aug - 25 Aug
Embassy Suites Louisville Downtown
21c Museum Hotel Louisville
Front of property

21c Museum Hotel Louisville

4.5 star property
9.2 out of 10, Wonderful, (1001)
"Favorite in Louisville - such a fun & unique hotel "
The price is €156
includes taxes & fees
31 Aug - 1 Sept
21c Museum Hotel Louisville
Hotel Genevieve part of JdV by Hyatt
3 bars/lounges, cocktail bar, rooftop bar

Hotel Genevieve part of JdV by Hyatt

4.0 star property
9.2 out of 10, Wonderful, (933)
"Always a lovely visit! "
The price is €127
includes taxes & fees
17 Aug - 18 Aug
Hotel Genevieve part of JdV by Hyatt
The Brown Hotel
Lobby

The Brown Hotel

4.5 star property
9.4 out of 10, Exceptional, (1046)
"Beautiful hotel, great location, helpful staff. Will definitely stay here again"
The price is €144
includes taxes & fees
17 Aug - 18 Aug
The Brown Hotel
Hyatt Regency Louisville
Breakfast, lunch and dinner served

Hyatt Regency Louisville

4.0 star property
8.8 out of 10, Excellent, (1003)
"Loved staying here! "
The price is €128
includes taxes & fees
1 Sept - 2 Sept
Hyatt Regency Louisville
The Grady
Deluxe Single Room, 1 King Bed, River View | View from room

The Grady

4.0 star property
9.4 out of 10, Exceptional, (1003)
"Great Stay!"
The price is €178
includes taxes & fees
1 Sept - 2 Sept
The Grady
Louisville Marriott Downtown
Restaurant

Louisville Marriott Downtown

4.0 star property
9.0 out of 10, Wonderful, (1002)
"Great stay. Thank you"
The price is €172
includes taxes & fees
22 Aug - 23 Aug
Louisville Marriott Downtown
Hotel Distil, Autograph Collection
Exterior

Hotel Distil, Autograph Collection

4.0 star property
9.6 out of 10, Exceptional, (397)
"Bed was very comfortable. Location was great!"
The price is €176
includes taxes & fees
24 Aug - 25 Aug
Hotel Distil, Autograph Collection
Hotel Bourré Bonne Louisville, Curio Collection by Hilton
Exterior

Hotel Bourré Bonne Louisville, Curio Collection by Hilton

4.0 star property
9.2 out of 10, Wonderful, (28)
"Lovely location and friendly staff."
The price is €170
includes taxes & fees
1 Sept - 2 Sept
Hotel Bourré Bonne Louisville, Curio Collection by Hilton
DoubleTree by Hilton Evansville
View from room

DoubleTree by Hilton Evansville

4.0 star property
8.6 out of 10, Excellent, (1000)
"Awesome place to stay"
The price is €99
includes taxes & fees
1 Sept - 2 Sept
DoubleTree by Hilton Evansville
Seelbach Hilton Louisville Downtown
Lobby

Seelbach Hilton Louisville Downtown

4.0 star property
8.6 out of 10, Excellent, (1001)
"Love this hotel and my stay was wonderful!"
The price is €141
includes taxes & fees
29 Aug - 30 Aug
Seelbach Hilton Louisville Downtown
Envi Boutique Hotel
65-inch flat-screen TV with digital channels

Envi Boutique Hotel

4.0 star property
8.0 out of 10, Very good, (259)
"Room was clean. Bed was comfortable Morning breakfast was nice. "
The price is €103
includes taxes & fees
22 Aug - 23 Aug
Envi Boutique Hotel
Stellar Suites
Signature Suite, 1 Queen Bed, Non Smoking

Stellar Suites

4.5 star property
9.6 out of 10, Exceptional, (101)
"Great spot a must stay"
The price is €162
includes taxes & fees
31 Aug - 1 Sept
Stellar Suites
The Pepin Mansion Historic B&B
Deluxe Room, 1 King Bed (Culbertson Suite) | Balcony

The Pepin Mansion Historic B&B

4.0 star property
9.8 out of 10, Exceptional, (614)
"Ryan was a great innkeeper! Very friendly and helpful and serve delicious breakfast! Loved the history and beauty of the mansion."
The price is €86
includes taxes & fees
19 Aug - 20 Aug
The Pepin Mansion Historic B&B
CozySuites at Nulu
Seasonal outdoor pool

CozySuites at Nulu

4.0 star property
8.0 out of 10, Very good, (20)
"Wonderful stay - great spot and lots of great dining options and bars nearby "
The price is €169
includes taxes & fees
19 Aug - 20 Aug
CozySuites at Nulu
stayAPT Suites Louisville North-Clarksville
BBQ/picnic Area

stayAPT Suites Louisville North-Clarksville

4.0 star property
9.8 out of 10, Exceptional, (41)
"It was very nice. Plenty of room to move around. Staff was very good to work with."
stayAPT Suites Louisville North-Clarksville
Spacious 3 BR Ranch House W Patio Yard in a Quiet Suburb
Exterior detail

Spacious 3 BR Ranch House W Patio Yard in a Quiet Suburb

4.0 star property
9.4 out of 10, Exceptional, (10)
"Very nice house in a nice neighborhood, spacious home environmental, felt more that at home there,"
Spacious 3 BR Ranch House W Patio Yard in a Quiet Suburb
Holiday Inn Evansville Airport
Lounge

Holiday Inn Evansville Airport

4.0 star property
8.0 out of 10, Very good, (604)
"Nice hotel but it doesn’t have a fridge in the room or microwave."
Holiday Inn Evansville Airport
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Learn more about Southern Indiana

Find lots to see and do in Southern Indiana—live music, sports teams and sights from Patoka Lake Swimming Beach to Patoka Lake.

See all hotels in Southern Indiana
Kentucky Center for the Performing Arts which includes modern architecture

Top Southern Indiana Hotel Reviews

Frequently asked questions

What are the best 4-star hotels in Southern Indiana?
Based on reviews by our guests, Galt House Hotel Trademark Collection by Wyndham is among the best 4-star hotels in Southern Indiana. Situated in Louisville, it includes massage services and beauty services. Hyatt Regency Louisville is another sought-after option here. Also with a 4-star rating and offering premium bedding and designer toiletries, you're sure to have a comfortable stay.
How much does it cost to stay in a 4-star hotel in Southern Indiana?
To book a 4-star hotel in Southern Indiana that's within your budget, take advantage of Expedia's handy filters. Take a look at what's available during your preferred dates and use our pricing filter to set your limit. You can also sort your results by the most budget-friendly option first.

  • Search for the lowest price from €86

What's the difference between 5-star and 4-star hotels in Southern Indiana?
Give yourself the luxury treatment during your Southern Indiana escape by checking in to a 4-star hotel. As well as featuring upmarket surroundings, these properties are typically packed with amenities such as large beds, bathrobes and plenty more. A 5-star hotel will go the extra mile to make your stay an even more indulgent and memorable one. 24-hour concierge assistance, luxurious spas and world-class dining are a few of the exclusive services and conveniences you'll likely be able to enjoy.