4 Star Hotels in Southern Indiana, United States of America

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Check availability on Southern Indiana 4 Star Hotels

Tonight
9 Jan - 10 Jan
Tomorrow
10 Jan - 11 Jan
This weekend
9 Jan - 11 Jan
Next weekend
16 Jan - 18 Jan

Our top choices for Southern Indiana 4-star hotels

4 restaurants, breakfast, lunch, dinner served; American cuisine
Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham
4.0 star property
Downtown Louisville
9.0 out of 10, Wonderful, (3,966 reviews)
"Great stay"
United States
Carlos
The price is €134
includes taxes & fees
16 Jan - 17 Jan
Galt House Hotel Trademark Collection by Wyndham
3 bars/lounges, cocktail bar, lobby lounge
Omni Louisville Hotel

Omni Louisville Hotel

Omni Louisville Hotel
4.0 star property
Downtown Louisville
9.2 out of 10, Wonderful, (1,758 reviews)
"This is a beautiful hotel in a great location. Very kind staff and helpful with directions."
United States
Bonnie
The price is €169
includes taxes & fees
24 Jan - 25 Jan
Omni Louisville Hotel
Reception
Embassy Suites Louisville Downtown

Embassy Suites Louisville Downtown

Embassy Suites Louisville Downtown
4.0 star property
Downtown Louisville
9.0 out of 10, Wonderful, (1,148 reviews)
"Great room and breakfast. Close to several nice restaurants."
United States
Crystal
The price is €122
includes taxes & fees
26 Jan - 27 Jan
Embassy Suites Louisville Downtown
Lobby
The Brown Hotel

The Brown Hotel

The Brown Hotel
4.5 star property
Downtown Louisville
9.4 out of 10, Exceptional, (1,171 reviews)
"Fantastic place to stay in Louisville."
United States
Nathaniel
The Brown Hotel
Terrace/patio
Hotel Genevieve part of JdV by Hyatt

Hotel Genevieve part of JdV by Hyatt

Hotel Genevieve part of JdV by Hyatt
4.0 star property
Downtown Louisville
9.2 out of 10, Wonderful, (1,026 reviews)
"Spotless room and courteous staff "
United States
Mary
The price is €117
includes taxes & fees
12 Jan - 13 Jan
Hotel Genevieve part of JdV by Hyatt
Front of property
21c Museum Hotel Louisville

21c Museum Hotel Louisville

21c Museum Hotel Louisville
4.5 star property
Downtown Louisville
9.2 out of 10, Wonderful, (1,004 reviews)
"Excellent place. "
United States
Anatole
The price is €132
includes taxes & fees
31 Jan - 1 Feb
21c Museum Hotel Louisville
Lobby
Hyatt Regency Louisville

Hyatt Regency Louisville

Hyatt Regency Louisville
4.0 star property
Downtown Louisville
8.8 out of 10, Excellent, (1,001 reviews)
"Great hotel close to 4th street. Overall nice stay. "
United States
Collin
The price is €149
includes taxes & fees
18 Jan - 19 Jan
Hyatt Regency Louisville
Lobby
The Grady

The Grady

The Grady
4.0 star property
Downtown Louisville
9.4 out of 10, Exceptional, (1,000 reviews)
"Such an amazing hotel...restaurant is delicious! "
United States
Craig
The price is €146
includes taxes & fees
16 Jan - 17 Jan
The Grady
Exterior
Louisville Marriott Downtown

Louisville Marriott Downtown

Louisville Marriott Downtown
4.0 star property
Downtown Louisville
9.0 out of 10, Wonderful, (1,001 reviews)
"Very nice hotel. Great stay!"
United States
Brad
The price is €173
includes taxes & fees
1 Feb - 2 Feb
Louisville Marriott Downtown
Terrace/patio
Hotel Distil, Autograph Collection

Hotel Distil, Autograph Collection

Hotel Distil, Autograph Collection
4.0 star property
Downtown Louisville
9.6 out of 10, Exceptional, (432 reviews)
"Clean, well appointed, convenient to restaurants and downtown Louisville."
United States
Chris
The price is €177
includes taxes & fees
8 Feb - 9 Feb
Hotel Distil, Autograph Collection
Lobby
DoubleTree by Hilton Evansville

DoubleTree by Hilton Evansville

DoubleTree by Hilton Evansville
4.0 star property
Downtown Evansville
8.6 out of 10, Excellent, (1,002 reviews)
"The staff were extremely friendly "
United States
Jill
The price is €96
includes taxes & fees
18 Jan - 19 Jan
DoubleTree by Hilton Evansville
Exterior
Hotel Bourré Bonne Louisville, Curio Collection by Hilton

Hotel Bourré Bonne Louisville, Curio Collection by Hilton

Hotel Bourré Bonne Louisville, Curio Collection by Hilton
4.0 star property
Downtown Louisville
9.2 out of 10, Wonderful, (62 reviews)
"Amazing property! Best hotel in Louisville! Will be staying there again!"
United States
Norman
The price is €170
includes taxes & fees
21 Jan - 22 Jan
Hotel Bourré Bonne Louisville, Curio Collection by Hilton
Exterior
Seelbach Hilton Louisville Downtown

Seelbach Hilton Louisville Downtown

Seelbach Hilton Louisville Downtown
4.0 star property
Downtown Louisville
8.6 out of 10, Excellent, (1,001 reviews)
"Excellent location and a great lobby bar with a top notch bourbon selection. "
United States
vincent
The price is €144
includes taxes & fees
16 Jan - 17 Jan
Seelbach Hilton Louisville Downtown
Lounge
Stellar Suites

Stellar Suites

Stellar Suites
4.5 star property
Downtown Louisville
9.6 out of 10, Exceptional, (118 reviews)
"The check-in process was simple and easy, the room was spotless and had so many amenities. "
United States
Grace
The price is €162
includes taxes & fees
23 Jan - 24 Jan
Stellar Suites
Property entrance
The Pepin Mansion Historic B&B

The Pepin Mansion Historic B&B

The Pepin Mansion Historic B&B
4.0 star property
New Albany
9.8 out of 10, Exceptional, (651 reviews)
"This is our second visit this year. Lovely and comfortable rooms. Breakfast was wonderful "
United States
douglas f
The price is €86
includes taxes & fees
11 Jan - 12 Jan
The Pepin Mansion Historic B&B
Seasonal outdoor pool
CozySuites at Nulu

CozySuites at Nulu

CozySuites at Nulu
4.0 star property
Downtown Louisville
8.2 out of 10, Very good, (26 reviews)
"The unit was clean, all communications were timely, the property has all the amenities, and NULU is very walkable. A perfect stay! My only regret is that I wasn't able to extend the stay. Highly recommended if you're in the Louisville area "
United States
William
The price is €168
includes taxes & fees
27 Jan - 28 Jan
CozySuites at Nulu
Exterior
stayAPT Suites Louisville North-Clarksville

stayAPT Suites Louisville North-Clarksville

stayAPT Suites Louisville North-Clarksville
4.0 star property
Clarksville
9.8 out of 10, Exceptional, (46 reviews)
"room very good i love hotel ❤️"
United States
Kartar
The price is €144
includes taxes & fees
12 Jan - 13 Jan
stayAPT Suites Louisville North-Clarksville
32-inch Smart TV with cable channels
The Reserve on Main

The Reserve on Main

The Reserve on Main
4.0 star property
Downtown Louisville
10.0 out of 10, Exceptional, (1 review)
"Incredible stay. This stay was clean and inspiring for anyone wishing to take a break and recharge. We highly recommend this stay to everyone staying in the city. "
Canada
georgios
The price is €207
includes taxes & fees
14 Jan - 15 Jan
The Reserve on Main
Family House, Multiple Beds | Private kitchen
Spacious 3 BR Ranch House W Patio Yard in a Quiet Suburb

Spacious 3 BR Ranch House W Patio Yard in a Quiet Suburb

Spacious 3 BR Ranch House W Patio Yard in a Quiet Suburb
4.0 star property
Sellersburg
9.4 out of 10, Exceptional, (10 reviews)
"Very nice house in a nice neighborhood, spacious home environmental, felt more that at home there,"
United States
Tammy
Spacious 3 BR Ranch House W Patio Yard in a Quiet Suburb
Lounge
Holiday Inn Evansville Airport

Holiday Inn Evansville Airport

Holiday Inn Evansville Airport
4.0 star property
Evansville
8.0 out of 10, Very good, (604 reviews)
"Nice hotel but it doesn’t have a fridge in the room or microwave."
United States
Anonymous traveller
Holiday Inn Evansville Airport
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Learn more about Southern Indiana

Find lots to see and do in Southern Indiana—live music, sports teams and sights from Patoka Lake Swimming Beach to Patoka Lake.

See all hotels in Southern Indiana
Belle of Louisville featuring a bay or harbour and a ferry as well as a small group of people

Top Southern Indiana Hotel Reviews

DoubleTree by Hilton Evansville

DoubleTree by Hilton Evansville

10/10 Excellent
"Didnt eat breakfast. "
Steven 1-night trip
Posted 3 weeks ago
DoubleTree by Hilton Evansville

Frequently asked questions

What are the best 4-star hotels in Southern Indiana?
Based on reviews by our guests, Galt House Hotel Trademark Collection by Wyndham is among the best 4-star hotels in Southern Indiana. Situated in Louisville, it includes massage services and beauty services. Hyatt Regency Louisville is another sought-after option here. Also with a 4-star rating and offering premium bedding and designer toiletries, you're sure to have a comfortable stay.
How much does it cost to stay in a 4-star hotel in Southern Indiana?
To book a 4-star hotel in Southern Indiana that's within your budget, take advantage of Expedia's handy filters. Take a look at what's available during your preferred dates and use our pricing filter to set your limit. You can also sort your results by the most budget-friendly option first.

  • Search for the lowest price from €86

What's the difference between 5-star and 4-star hotels in Southern Indiana?
Give yourself the luxury treatment during your Southern Indiana escape by checking in to a 4-star hotel. As well as featuring upmarket surroundings, these properties are typically packed with amenities such as large beds, bathrobes and plenty more. A 5-star hotel will go the extra mile to make your stay an even more indulgent and memorable one. 24-hour concierge assistance, luxurious spas and world-class dining are a few of the exclusive services and conveniences you'll likely be able to enjoy.