4 Star Hotels in Southern Indiana, United States of America

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Check availability on Southern Indiana 4 Star Hotels

This weekend
29 May - 31 May
Next weekend
5 Jun - 7 Jun

Our top choices for Southern Indiana 4-star hotels

4 restaurants; breakfast, lunch, and dinner served

Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham
4.0 star property
Downtown Louisville
9.0 out of 10, Wonderful, (4,193 reviews)
"The staff was super friendly and the stay was very comfortable!"
United States
James
The price is €150
includes taxes & fees
7 Jun - 8 Jun
Galt House Hotel Trademark Collection by Wyndham
3 bars/lounges, cocktail bar, lobby lounge

Omni Louisville Hotel

Omni Louisville Hotel
4.0 star property
Downtown Louisville
9.4 out of 10, Exceptional, (1,893 reviews)
"Great place to stay, perfect location "
United States
Ben
The price is €181
includes taxes & fees
2 Jun - 3 Jun
Omni Louisville Hotel
Lobby

The Brown Hotel

The Brown Hotel
4.5 star property
Downtown Louisville
9.4 out of 10, Exceptional, (1,228 reviews)
"Breakfast menu was great, bartender, and drinks were wonderful!"
United States
hannah
The price is €208
includes taxes & fees
31 May - 1 Jun
The Brown Hotel
Reception

Embassy Suites Louisville Downtown

Embassy Suites Louisville Downtown
4.0 star property
Downtown Louisville
9.0 out of 10, Wonderful, (1,250 reviews)
"Clean, great staff!"
United States
Natali
The price is €118
includes taxes & fees
14 Jun - 15 Jun
Embassy Suites Louisville Downtown
Lobby

Hyatt Regency Louisville

Hyatt Regency Louisville
4.0 star property
Downtown Louisville
8.8 out of 10, Excellent, (1,002 reviews)
"The hotel is perfectly located and the amenities are great!"
United States
Marcus
The price is €162
includes taxes & fees
31 May - 1 Jun
Hyatt Regency Louisville
Terrace/patio

Hotel Genevieve part of JdV by Hyatt

Hotel Genevieve part of JdV by Hyatt
4.0 star property
Downtown Louisville
9.2 out of 10, Wonderful, (1,094 reviews)
"Adorable rooms and great spaces in the lobby to work. "
United States
Marissa
The price is €136
includes taxes & fees
3 Jun - 4 Jun
Hotel Genevieve part of JdV by Hyatt
Front of property

21c Museum Hotel Louisville

21c Museum Hotel Louisville
4.5 star property
Downtown Louisville
9.4 out of 10, Exceptional, (1,002 reviews)
"Unique venue with some many amenities. Staff are super helpful and hospital. Will stay again when I’m in town."
United States
Jason
The price is €158
includes taxes & fees
21 Jun - 22 Jun
21c Museum Hotel Louisville
Exterior

Louisville Marriott Downtown

Louisville Marriott Downtown
4.0 star property
Downtown Louisville
9.0 out of 10, Wonderful, (1,000 reviews)
"Bar was great."
United Kingdom
Pete
The price is €199
includes taxes & fees
21 Jun - 22 Jun
Louisville Marriott Downtown
Terrace/patio

Hotel Distil, Autograph Collection

Hotel Distil, Autograph Collection
4.0 star property
Downtown Louisville
9.6 out of 10, Exceptional, (467 reviews)
"Bar and restaurant were amazing!!"
Canada
Cheryl
The price is €187
includes taxes & fees
14 Jun - 15 Jun
Hotel Distil, Autograph Collection
Lobby

The Grady

The Grady
4.0 star property
Downtown Louisville
9.4 out of 10, Exceptional, (1,004 reviews)
"Had a wonderful stay and the staff were so friendly!"
United States
Tanya
The price is €187
includes taxes & fees
14 Jun - 15 Jun
The Grady
Terrace/patio

Hotel Bourré Bonne Louisville, Curio Collection by Hilton

Hotel Bourré Bonne Louisville, Curio Collection by Hilton
4.0 star property
Downtown Louisville
9.4 out of 10, Exceptional, (108 reviews)
"Very nice and quiet hotel."
United States
Sandy
The price is €198
includes taxes & fees
7 Jun - 8 Jun
Hotel Bourré Bonne Louisville, Curio Collection by Hilton
Lobby

DoubleTree by Hilton Evansville

DoubleTree by Hilton Evansville
4.0 star property
Downtown Evansville
8.6 out of 10, Excellent, (1,001 reviews)
"Great location…nice rooms"
United States
Steven
The price is €100
includes taxes & fees
21 Jun - 22 Jun
DoubleTree by Hilton Evansville
Exterior

Seelbach Hilton Louisville Downtown

Seelbach Hilton Louisville Downtown
4.0 star property
Downtown Louisville
8.6 out of 10, Excellent, (1,001 reviews)
"Great place to stay. Highly recommend. "
United States
Justin
The price is €154
includes taxes & fees
6 Jun - 7 Jun
Seelbach Hilton Louisville Downtown
Lounge

Stellar Suites

Stellar Suites
4.5 star property
Downtown Louisville
9.6 out of 10, Exceptional, (135 reviews)
"Easy check in and check out process and very convenient location."
United States
Richard
The price is €152
includes taxes & fees
2 Jun - 3 Jun
Stellar Suites
Exterior

stayAPT Suites Louisville North-Clarksville

stayAPT Suites Louisville North-Clarksville
4.0 star property
Clarksville
9.8 out of 10, Exceptional, (49 reviews)
"Every thing was great. Especially impressed by the kitchen."
United States
Ronald
The price is €145
includes taxes & fees
28 May - 29 May
stayAPT Suites Louisville North-Clarksville
Property entrance

The Pepin Mansion Historic B&B

The Pepin Mansion Historic B&B
4.0 star property
New Albany
9.8 out of 10, Exceptional, (689 reviews)
"Absolutely a beautiful comfy place to stay."
United States
Susan
The price is €82
includes taxes & fees
27 May - 28 May
The Pepin Mansion Historic B&B
Seasonal outdoor pool

CozySuites at Nulu

CozySuites at Nulu
4.0 star property
Downtown Louisville
7.8 out of 10, Good, (29 reviews)
"Wonderful stay - great spot and lots of great dining options and bars nearby "
United States
Roy
The price is €173
includes taxes & fees
27 May - 28 May
CozySuites at Nulu
Exterior

Bourbon Barrel Inn Bed & Breakfast

Bourbon Barrel Inn Bed & Breakfast
4.0 star property
Old Louisville
10.0 out of 10, Exceptional, (4 reviews)
"Inn Keepers were wonderful. "
United States
jonathan
Bourbon Barrel Inn Bed & Breakfast
32-inch Smart TV with cable channels

The Reserve on Main

The Reserve on Main
4.0 star property
Downtown Louisville
9.4 out of 10, Exceptional, (3 reviews)
"The room was great and clean. Great location. "
United States
De'Carlon
The Reserve on Main
Family House, Multiple Beds | Private kitchen

Spacious 3 BR Ranch House W Patio Yard in a Quiet Suburb

Spacious 3 BR Ranch House W Patio Yard in a Quiet Suburb
4.0 star property
Sellersburg
9.4 out of 10, Exceptional, (10 reviews)
"Very nice house in a nice neighborhood, spacious home environmental, felt more that at home there,"
United States
Tammy
Spacious 3 BR Ranch House W Patio Yard in a Quiet Suburb
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Top Southern Indiana Hotel Reviews

Frequently asked questions

What are the best 4-star hotels in Southern Indiana?
Based on reviews by our guests, Galt House Hotel Trademark Collection by Wyndham is among the best 4-star hotels in Southern Indiana. Situated in Louisville, it includes massage services and beauty services. Hyatt Regency Louisville is another sought-after option here. Also with a 4-star rating and offering premium bedding and designer toiletries, you're sure to have a comfortable stay.
How much does it cost to stay in a 4-star hotel in Southern Indiana?
To book a 4-star hotel in Southern Indiana that's within your budget, take advantage of Expedia's handy filters. Take a look at what's available during your preferred dates and use our pricing filter to set your limit. You can also sort your results by the most budget-friendly option first.

  • Search for the lowest price from €82

What's the difference between 5-star and 4-star hotels in Southern Indiana?
Give yourself the luxury treatment during your Southern Indiana escape by checking in to a 4-star hotel. As well as featuring upmarket surroundings, these properties are typically packed with amenities such as large beds, bathrobes and plenty more. A 5-star hotel will go the extra mile to make your stay an even more indulgent and memorable one. 24-hour concierge assistance, luxurious spas and world-class dining are a few of the exclusive services and conveniences you'll likely be able to enjoy.