4 Star Hotels in Southern Indiana, United States of America

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Southern Indiana 4 Star Hotels

Tonight
25 Nov - 26 Nov
Tomorrow
26 Nov - 27 Nov
This weekend
28 Nov - 30 Nov
Next weekend
5 Dec - 7 Dec

Top Southern Indiana 4 Star Hotels

4 restaurants, breakfast, lunch, dinner served; American cuisine
Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham

4.0 star property
Downtown Louisville
9.0 out of 10, Wonderful, (3801)
"Great place to stay "
United States
Tia
The price is €95
includes taxes & fees
15 Dec - 16 Dec
Galt House Hotel Trademark Collection by Wyndham
Sauna, body treatments, aromatherapy, hot stone massages
Omni Louisville Hotel

Omni Louisville Hotel

4.0 star property
Downtown Louisville
9.2 out of 10, Wonderful, (1697)
"Wonderful property and staff. Would love to stay again. "
United States
Hanna
The price is €203
includes taxes & fees
27 Nov - 28 Nov
Omni Louisville Hotel
Dinner served
Embassy Suites Louisville Downtown

Embassy Suites Louisville Downtown

4.0 star property
Downtown Louisville
9.0 out of 10, Wonderful, (1088)
"Clean, hotel was amazing, great breakfast "
United States
Alana
The price is €122
includes taxes & fees
3 Dec - 4 Dec
Embassy Suites Louisville Downtown
Lobby
The Brown Hotel

The Brown Hotel

4.5 star property
Downtown Louisville
9.4 out of 10, Exceptional, (1131)
"Wonderful hotel with lots of history; clean rooms; Nice lounge and restaurants."
United States
Kim
The price is €121
includes taxes & fees
26 Nov - 27 Nov
The Brown Hotel
Hypo-allergenic bedding, in-room safe, desk, laptop workspace
Hotel Genevieve part of JdV by Hyatt

Hotel Genevieve part of JdV by Hyatt

4.0 star property
Downtown Louisville
9.2 out of 10, Wonderful, (1009)
"Great stay"
United States
Katharine
The price is €138
includes taxes & fees
30 Nov - 1 Dec
Hotel Genevieve part of JdV by Hyatt
Front of property
21c Museum Hotel Louisville

21c Museum Hotel Louisville

4.5 star property
Downtown Louisville
9.2 out of 10, Wonderful, (1005)
" Loved our stay, would definitely plan to come back if we are ever in the area again."
United States
Erica
The price is €187
includes taxes & fees
26 Nov - 27 Nov
21c Museum Hotel Louisville
Breakfast, lunch and dinner served
Hyatt Regency Louisville

Hyatt Regency Louisville

4.0 star property
Downtown Louisville
8.8 out of 10, Excellent, (1008)
"Enjoyed our stay "
United States
Jedediah
The price is €119
includes taxes & fees
28 Nov - 29 Nov
Hyatt Regency Louisville
Deluxe Single Room, 1 King Bed, River View | View from room
The Grady

The Grady

4.0 star property
Downtown Louisville
9.4 out of 10, Exceptional, (1011)
"The location was outstanding and atmosphere was very nice."
United States
Malcolm
The price is €149
includes taxes & fees
26 Nov - 27 Nov
The Grady
Restaurant
Louisville Marriott Downtown

Louisville Marriott Downtown

4.0 star property
Downtown Louisville
9.0 out of 10, Wonderful, (1002)
"Room was great, but the service by the attendant that wait on me was exceptional in what she done for me."
United States
Michael
The price is €175
includes taxes & fees
30 Nov - 1 Dec
Louisville Marriott Downtown
Exterior
Hotel Distil, Autograph Collection

Hotel Distil, Autograph Collection

4.0 star property
Downtown Louisville
9.6 out of 10, Exceptional, (425)
"Really a nice place to stay "
United States
Jeanie
The price is €173
includes taxes & fees
30 Nov - 1 Dec
Hotel Distil, Autograph Collection
View from room
DoubleTree by Hilton Evansville

DoubleTree by Hilton Evansville

4.0 star property
Downtown Evansville
8.6 out of 10, Excellent, (1003)
"The staff were extremely friendly "
United States
Jill
The price is €97
includes taxes & fees
7 Dec - 8 Dec
DoubleTree by Hilton Evansville
Exterior
Hotel Bourré Bonne Louisville, Curio Collection by Hilton

Hotel Bourré Bonne Louisville, Curio Collection by Hilton

4.0 star property
Downtown Louisville
9.0 out of 10, Wonderful, (48)
"Lovely hotel in downtown Louisville. Well appointed room, comfy bed and outstanding dining. "
United States
Michelle
The price is €175
includes taxes & fees
25 Dec - 26 Dec
Hotel Bourré Bonne Louisville, Curio Collection by Hilton
Lobby
Seelbach Hilton Louisville Downtown

Seelbach Hilton Louisville Downtown

4.0 star property
Downtown Louisville
8.6 out of 10, Excellent, (1004)
"This was a lovely stay and we will definitely return. "
United States
Dolorse
The price is €129
includes taxes & fees
21 Dec - 22 Dec
Seelbach Hilton Louisville Downtown
Signature Suite, 1 Queen Bed, Non Smoking
Stellar Suites

Stellar Suites

4.5 star property
Downtown Louisville
9.6 out of 10, Exceptional, (114)
"Clean and great location "
United States
Greg
The price is €164
includes taxes & fees
9 Dec - 10 Dec
Stellar Suites
Deluxe Room, 1 King Bed (Culbertson Suite) | Balcony
The Pepin Mansion Historic B&B

The Pepin Mansion Historic B&B

4.0 star property
New Albany
9.8 out of 10, Exceptional, (645)
"Have stayed here once before. Accommodations are wonderful and the sit down breakfast is lovely. Highly recommend this beautiful property."
United States
Kathy
The price is €87
includes taxes & fees
26 Nov - 27 Nov
The Pepin Mansion Historic B&B
Seasonal outdoor pool
CozySuites at Nulu

CozySuites at Nulu

4.0 star property
Downtown Louisville
8.2 out of 10, Very good, (26)
"The unit was clean, all communications were timely, the property has all the amenities, and NULU is very walkable. A perfect stay! My only regret is that I wasn't able to extend the stay. Highly recommended if you're in the Louisville area "
United States
William
The price is €174
includes taxes & fees
26 Nov - 27 Nov
CozySuites at Nulu
BBQ/picnic Area
stayAPT Suites Louisville North-Clarksville

stayAPT Suites Louisville North-Clarksville

4.0 star property
Clarksville
9.8 out of 10, Exceptional, (43)
"Excellent stay. One of my favorite hotels in the area. They never disappoint "
United States
Julia
The price is €156
includes taxes & fees
26 Nov - 27 Nov
stayAPT Suites Louisville North-Clarksville
32-inch Smart TV with cable channels
The Reserve on Main

The Reserve on Main

4.0 star property
Downtown Louisville
10.0 out of 10, Exceptional, (1)
"Incredible stay. This stay was clean and inspiring for anyone wishing to take a break and recharge. We highly recommend this stay to everyone staying in the city. "
Canada
georgios
The price is €179
includes taxes & fees
30 Nov - 1 Dec
The Reserve on Main
Exterior detail
Spacious 3 BR Ranch House W Patio Yard in a Quiet Suburb

Spacious 3 BR Ranch House W Patio Yard in a Quiet Suburb

4.0 star property
Sellersburg
9.4 out of 10, Exceptional, (10)
"Very nice house in a nice neighborhood, spacious home environmental, felt more that at home there,"
United States
Tammy
Spacious 3 BR Ranch House W Patio Yard in a Quiet Suburb
Lounge
Holiday Inn Evansville Airport

Holiday Inn Evansville Airport

4.0 star property
Evansville
8.0 out of 10, Very good, (604)
"Nice hotel but it doesn’t have a fridge in the room or microwave."
United States
Anonymous traveller
Holiday Inn Evansville Airport
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Learn more about Southern Indiana

Find lots to see and do in Southern Indiana—live music, sports teams and sights from Patoka Lake Swimming Beach to Patoka Lake.

See all hotels in Southern Indiana
Belle of Louisville featuring a bay or harbour and a ferry as well as a small group of people

Top Southern Indiana Hotel Reviews

DoubleTree by Hilton Evansville

DoubleTree by Hilton Evansville

10/10 Excellent
"Great stay!"
Amy 1-night trip
Posted 10 days ago
DoubleTree by Hilton Evansville

Frequently asked questions

What are the best 4-star hotels in Southern Indiana?
Based on reviews by our guests, Galt House Hotel Trademark Collection by Wyndham is among the best 4-star hotels in Southern Indiana. Situated in Louisville, it includes massage services and beauty services. Hyatt Regency Louisville is another sought-after option here. Also with a 4-star rating and offering premium bedding and designer toiletries, you're sure to have a comfortable stay.
How much does it cost to stay in a 4-star hotel in Southern Indiana?
To book a 4-star hotel in Southern Indiana that's within your budget, take advantage of Expedia's handy filters. Take a look at what's available during your preferred dates and use our pricing filter to set your limit. You can also sort your results by the most budget-friendly option first.

  • Search for the lowest price from €87

What's the difference between 5-star and 4-star hotels in Southern Indiana?
Give yourself the luxury treatment during your Southern Indiana escape by checking in to a 4-star hotel. As well as featuring upmarket surroundings, these properties are typically packed with amenities such as large beds, bathrobes and plenty more. A 5-star hotel will go the extra mile to make your stay an even more indulgent and memorable one. 24-hour concierge assistance, luxurious spas and world-class dining are a few of the exclusive services and conveniences you'll likely be able to enjoy.

Explore a world of travel with Expedia