A modern glass building with a curved facade and a sign reading "The Kentucky Center".

4 Star Hotels in Southern Indiana, United States of America

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Check availability on Southern Indiana 4 Star Hotels

Tonight
15 Oct - 16 Oct
Tomorrow
16 Oct - 17 Oct
This weekend
16 Oct - 18 Oct
Next weekend
23 Oct - 25 Oct

Our top choices for Southern Indiana 4-star hotels

A modern interior with large windows offering a city view, a circular light fixture, and leather seating.
A balcony with a view of a river, a bridge, and a cityscape.
A nighttime view of The GALT and The Galthouse buildings with illuminated signage, a busy street with light trails from moving vehicles, and a modern urban setting.
A modern bar with a long counter, multiple shelves of liquor bottles, and cushioned bar stools.

1. Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham
Downtown Louisville
United States
Mark
€152
includes taxes & fees
25 Oct - 26 Oct
Galt House Hotel Trademark Collection by Wyndham
A spacious lobby with a high ceiling, a central chandelier, and seating areas with tables and chairs.
A lobby with a marble floor, a reception desk, and a large chandelier.
A modern interior with a fireplace, bookshelves, and seating areas.
A rooftop bar with outdoor seating, including sofas and chairs, and a bar area with a television screen.

2. Omni Louisville Hotel

Omni Louisville Hotel
Downtown Louisville
United States
Samantha
€132
includes taxes & fees
18 Oct - 19 Oct
Omni Louisville Hotel
A grand lobby with ornate columns, plush seating, and a chandelier.
A grand lobby with ornate ceiling, large windows, and classic furniture.
A grand dining area with ornate ceiling, chandeliers, and a bar area with a sign reading "Cigar Bar".
A grand lobby with ornate ceiling, multiple seating areas, and a staircase.

3. The Brown Hotel

The Brown Hotel
Downtown Louisville
United States
John
€132
includes taxes & fees
28 Oct - 29 Oct
The Brown Hotel
A spacious lobby with a blue sofa, a wooden coffee table, and a chandelier.
An indoor swimming pool with clear water, surrounded by white marble walls and columns, and furnished with lounge chairs and tables.
A hotel dining area with long tables, booths, and a bar.
A modern hotel room with a living area, a dining area, and a bedroom.

4. Embassy Suites Louisville Downtown

Embassy Suites Louisville Downtown
Downtown Louisville
United States
Frances
€137
includes taxes & fees
15 Nov - 16 Nov
Embassy Suites Louisville Downtown
A modern lobby with a curved metallic structure, a seating area with a sofa and a small table, and an escalator in the background.
A hotel room with a large bed, a desk, a chair, a sofa, and a view of a cityscape through the window.
A reception area with a wooden wall and a neon sign that reads "Sway LOCAL SOUTHERN EATERY".
A modern indoor swimming pool with clear glass walls, lounge chairs, and a wooden wall in the background.

5. Hyatt Regency Louisville

Hyatt Regency Louisville
Downtown Louisville
United States
Lester
€174
includes taxes & fees
29 Oct - 30 Oct
Hyatt Regency Louisville
A modern building with a restaurant on the ground floor, featuring large windows and outdoor seating.
A spacious lobby with a bar area, seating arrangements, and a visible kitchen bar.
A modern hotel room with a large window offering a city view, a cozy seating area with a sofa and chairs, a dining table with lamps, and a wooden floor.
A reception area with marble counters, modern pendant lighting, and potted orchids.

6. Louisville Marriott Downtown

Louisville Marriott Downtown
Downtown Louisville
United States
Jason
€145
includes taxes & fees
13 Nov - 14 Nov
Louisville Marriott Downtown
A classical gold statue in front of a multi-story building with large windows and a brick facade.
A cozy room with wooden walls, a table with a lamp, and shelves displaying books and decorative items.
A cozy room with a geometric-patterned ceiling, a sofa, and a chair.
A restaurant with multiple dining tables, a long bench seating area, and framed artwork on the walls.

7. 21c Museum Hotel Louisville

21c Museum Hotel Louisville
Downtown Louisville
United States
Matt
€165
includes taxes & fees
8 Nov - 9 Nov
21c Museum Hotel Louisville
A room with a checkered floor, leather armchairs, a sofa, and a small table with a glass. There are windows with arched tops and a view of buildings outside.
A yellow coffee shop counter with a menu board above, displaying various coffee and food items.
A bedroom with a bed, a chair, a TV, and a window with curtains.
A bar area with a wooden bar counter, two stools, a chandelier, and a mirror.

8. Hotel Genevieve part of JdV by Hyatt

Hotel Genevieve part of JdV by Hyatt
Downtown Louisville
United States
Tyler
€142
includes taxes & fees
25 Oct - 26 Oct
Hotel Genevieve part of JdV by Hyatt
An indoor dining area with tables set for guests, surrounded by potted plants and hanging lights.
A multi-story hotel with a classic facade, large windows, and a modern glass building adjacent to it.
A bar with shelves of liquor bottles and a bartender preparing drinks.
An outdoor dining area with tables and chairs, a green building facade, and a row of plants along the wall.

9. Hotel Distil, Autograph Collection

Hotel Distil, Autograph Collection
Downtown Louisville
United States
Heather
€240
includes taxes & fees
8 Nov - 9 Nov
Hotel Distil, Autograph Collection
A modern interior with a fireplace, bookshelves, a green sofa, and leather chairs.
A modern restaurant interior with a staircase, round tables, and a brick wall.
A modern hotel room with a large bed, a desk with a flat-screen TV, a green armchair, and a view of the city through large windows.
A building with a sign reading "THE GRADY" at the entrance.

10. The Grady

The Grady
Downtown Louisville
United States
Donna
€164
includes taxes & fees
15 Nov - 16 Nov
The Grady
An outdoor seating area with sofas and tables, a fire feature, and a clock tower in the background.
A hotel with a prominent sign, a central courtyard with a sculpture, and a dome structure in the background.
A modern living room with a sofa, a coffee table, a side table with a plant, and a view of a building with a clock tower.
A modern hotel room with a large bed, a city view, and a unique headboard design.

11. Hotel Bourré Bonne Louisville, Curio Collection by Hilton

Hotel Bourré Bonne Louisville, Curio Collection by Hilton
Downtown Louisville
United States
Cameron
€189
includes taxes & fees
25 Oct - 26 Oct
Hotel Bourré Bonne Louisville, Curio Collection by Hilton
A modern hotel entrance with a covered walkway, a parking area, and a building with multiple floors.
A fountain with multiple jets of water in front of a building with a curved facade and large windows.
A conference room with round tables, chairs, and a carpeted floor.
An outdoor seating area with wicker chairs and a central fire feature, surrounded by potted plants and a brick wall.

12. DoubleTree by Hilton Evansville

DoubleTree by Hilton Evansville
Downtown Evansville
United States
CheyAnne
€104
includes taxes & fees
25 Oct - 26 Oct
DoubleTree by Hilton Evansville
A historic hotel with ornate architecture, a grand entrance, and a red carpet leading to the doors.
A grand lobby with marble floors, a staircase, and a reception desk.
A bakery display with pastries and bread, a coffee station, and a Christmas tree in the background.
A grand staircase with ornate railings and a marble floor, leading to a high-ceilinged lobby with decorative moldings and a chandelier.

13. Seelbach Hilton Louisville Downtown

Seelbach Hilton Louisville Downtown
Downtown Louisville
United States
Colleen
€173
includes taxes & fees
29 Oct - 30 Oct
Seelbach Hilton Louisville Downtown
A modern hotel lobby with a reception desk, seating area, and a staircase leading to the upper floor.
A modern KFC building with large glass windows, a prominent sign, and a well-lit entrance area.
A modern bedroom with a bed, a blue sofa, a large rug, and a TV on the wall.
A modern interior with a green wall, black chairs, and a ceiling with exposed beams and lights.

14. Stellar Suites

Stellar Suites
Downtown Louisville
United States
Kevin
€167
includes taxes & fees
18 Oct - 19 Oct
Stellar Suites
A grand entrance with a staircase leading to a door, flanked by two lamp posts and a bench.
A long table set with white tablecloths, gold chargers, and clear glassware.
A marble countertop with a tray of colorful glassware, a bottle, and two glasses. A framed painting hangs above, and two lamps are on either side.
A grand hallway with a wooden floor, a staircase, a chandelier, and a large mirror.

15. The Pepin Mansion Historic B&B

The Pepin Mansion Historic B&B
New Albany
United States
David
€128
includes taxes & fees
29 Oct - 30 Oct
The Pepin Mansion Historic B&B
A modern lounge with leather sofas, a coffee table, and a view of a classical building.
A narrow corridor with exposed brick walls, wooden flooring, and a seating area with tables and chairs.
A modern interior with a wooden dining table, leather sofas, and a bar area with shelves.
A modern living room with a leather sofa, two coffee tables, and a chessboard. There are shelves with bottles and glasses, and a large window on the right.

16. The Reserve on Main

The Reserve on Main
Downtown Louisville
United States
De'Carlon
The Reserve on Main
A rooftop pool area with multiple lounge chairs and umbrellas, surrounded by a high-rise building with balconies.
A modern kitchen with white cabinets, stainless steel appliances, and a dining area with a table and chairs.
A multi-story residential building with balconies, a brick facade, and large windows.
A modern living room with a dining area, a blue sofa, a ceiling fan, and a view of a balcony.

17. CozySuites at Nulu

CozySuites at Nulu
Downtown Louisville
United States
Jennifer
€202
includes taxes & fees
18 Oct - 19 Oct
CozySuites at Nulu
A modern hotel with a 'Stay Apt Suites' sign, featuring a brick facade, large windows, and a parking lot.
Terrace/patio
In-room dining
Private kitchen

18. stayAPT Suites Louisville North-Clarksville

stayAPT Suites Louisville North-Clarksville
Clarksville
Canada
Darlene
€151
includes taxes & fees
27 Oct - 28 Oct
stayAPT Suites Louisville North-Clarksville
A large, multi-story building with a prominent tower and multiple windows.
A large outdoor swimming pool with a Ferris wheel in the background.
A cozy seating area with two leather armchairs and a small round table. A table lamp and a wine glass are on the table.
A spacious living area with a large, ornate rug, a wooden bench, and a staircase with white balusters.

19. Bourbon Barrel Inn Bed & Breakfast

Bourbon Barrel Inn Bed & Breakfast
Old Louisville
United States
jonathan
Bourbon Barrel Inn Bed & Breakfast
A modern kitchen with wooden cabinets, a black microwave, and a stainless steel refrigerator.
A kitchen with a black refrigerator, a dining area with a table and chairs, and a living room with a blue sofa.
A kitchen with wooden cabinets, a refrigerator, a coffee maker, and a tiled backsplash.
A living room with a sofa, a coffee table, and a ceiling fan. There is a dining area with a table and chairs.

20. Spacious 3 BR Ranch House W Patio Yard in a Quiet Suburb

Spacious 3 BR Ranch House W Patio Yard in a Quiet Suburb
Sellersburg
United States
Tammy
Spacious 3 BR Ranch House W Patio Yard in a Quiet Suburb
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Learn more about Southern Indiana

Find lots to see and do in Southern Indiana—live music, sports teams and sights from Patoka Lake Swimming Beach to Patoka Lake.

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A riverboat with multiple decks and passengers, docked near a bridge.

Top Southern Indiana Hotel Reviews

Frequently asked questions

What are the best 4-star hotels in Southern Indiana?
Based on reviews by our guests, Galt House Hotel Trademark Collection by Wyndham is among the best 4-star hotels in Southern Indiana. Situated in Louisville, it includes massage services and beauty services. Hyatt Regency Louisville is another sought-after option here. Also with a 4-star rating and offering premium bedding and designer toiletries, you're sure to have a comfortable stay.
How much does it cost to stay in a 4-star hotel in Southern Indiana?
To book a 4-star hotel in Southern Indiana that's within your budget, take advantage of Expedia's handy filters. Take a look at what's available during your preferred dates and use our pricing filter to set your limit. You can also sort your results by the most budget-friendly option first.
  • Search for the lowest price from €104
What's the difference between 5-star and 4-star hotels in Southern Indiana?
Give yourself the luxury treatment during your Southern Indiana escape by checking in to a 4-star hotel. As well as featuring upmarket surroundings, these properties are typically packed with amenities such as large beds, bathrobes and plenty more. A 5-star hotel will go the extra mile to make your stay an even more indulgent and memorable one. 24-hour concierge assistance, luxurious spas and world-class dining are a few of the exclusive services and conveniences you'll likely be able to enjoy.

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