4 Star Hotels in Southern Indiana, United States of America

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Check availability on Southern Indiana 4 Star Hotels

Our top choices for Southern Indiana 4-star hotels

4 restaurants, breakfast, lunch, dinner served; American cuisine

Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham
4.0 star property
Downtown Louisville
9.0 out of 10, Wonderful, (4,147 reviews)
"Great service, rooms were clean and restaurant was fantastic"
United States
Joshua
The price is €153
includes taxes & fees
19 Apr - 20 Apr
Galt House Hotel Trademark Collection by Wyndham
3 bars/lounges, cocktail bar, lobby lounge

Omni Louisville Hotel

Omni Louisville Hotel
4.0 star property
Downtown Louisville
9.2 out of 10, Wonderful, (1,817 reviews)
"Clean room and great staff "
United States
Salvatore
The price is €200
includes taxes & fees
13 Apr - 14 Apr
Omni Louisville Hotel
Reception

Embassy Suites Louisville Downtown

Embassy Suites Louisville Downtown
4.0 star property
Downtown Louisville
9.0 out of 10, Wonderful, (1,189 reviews)
"Great location "
United States
Robert
The price is €160
includes taxes & fees
12 Apr - 13 Apr
Embassy Suites Louisville Downtown
Lobby

The Brown Hotel

The Brown Hotel
4.5 star property
Downtown Louisville
9.4 out of 10, Exceptional, (1,171 reviews)
"Amazing old hotel, great people."
United States
Colin
The price is €164
includes taxes & fees
13 Apr - 14 Apr
The Brown Hotel
Terrace/patio

Hotel Genevieve part of JdV by Hyatt

Hotel Genevieve part of JdV by Hyatt
4.0 star property
Downtown Louisville
9.2 out of 10, Wonderful, (1,072 reviews)
"Love this hotel"
United States
Gina
The price is €154
includes taxes & fees
10 May - 11 May
Hotel Genevieve part of JdV by Hyatt
Exterior

Louisville Marriott Downtown

Louisville Marriott Downtown
4.0 star property
Downtown Louisville
9.0 out of 10, Wonderful, (1,000 reviews)
"Great stay"
United States
Peter
The price is €230
includes taxes & fees
10 May - 11 May
Louisville Marriott Downtown
Front of property

21c Museum Hotel Louisville

21c Museum Hotel Louisville
4.5 star property
Downtown Louisville
9.4 out of 10, Exceptional, (1,003 reviews)
"Lovely hotel. Would stay there again."
United States
Kristin Woxland
The price is €166
includes taxes & fees
10 May - 11 May
21c Museum Hotel Louisville
Lobby

Hyatt Regency Louisville

Hyatt Regency Louisville
4.0 star property
Downtown Louisville
8.8 out of 10, Excellent, (1,002 reviews)
"Nice property, friendly staff, great downtown location "
United States
Matthew
The price is €183
includes taxes & fees
13 Apr - 14 Apr
Hyatt Regency Louisville
Terrace/patio

Hotel Distil, Autograph Collection

Hotel Distil, Autograph Collection
4.0 star property
Downtown Louisville
9.6 out of 10, Exceptional, (460 reviews)
"Great hotel & location"
United States
Ana
The price is €202
includes taxes & fees
10 May - 11 May
Hotel Distil, Autograph Collection
Lobby

The Grady

The Grady
4.0 star property
Downtown Louisville
9.4 out of 10, Exceptional, (1,012 reviews)
"Great hospitality by hosts plus restaurant Mark "
United States
ANTHONY
The price is €202
includes taxes & fees
10 May - 11 May
The Grady
Lobby

DoubleTree by Hilton Evansville

DoubleTree by Hilton Evansville
4.0 star property
Downtown Evansville
8.6 out of 10, Excellent, (1,001 reviews)
"The entire stay was perfect from check in to check out"
United States
Stephen
The price is €107
includes taxes & fees
3 May - 4 May
DoubleTree by Hilton Evansville
Terrace/patio

Hotel Bourré Bonne Louisville, Curio Collection by Hilton

Hotel Bourré Bonne Louisville, Curio Collection by Hilton
4.0 star property
Downtown Louisville
9.2 out of 10, Wonderful, (90 reviews)
"Very friendly and helpful staff. Hotel is clean and wonderful. "
United States
Emily
The price is €221
includes taxes & fees
19 Apr - 20 Apr
Hotel Bourré Bonne Louisville, Curio Collection by Hilton
Exterior

Seelbach Hilton Louisville Downtown

Seelbach Hilton Louisville Downtown
4.0 star property
Downtown Louisville
8.6 out of 10, Excellent, (1,000 reviews)
"Hotel was great, staff friendly, breakfast was great. Area was good around hotel, fun restaurants near by."
United States
Melisa
The price is €169
includes taxes & fees
4 May - 5 May
Seelbach Hilton Louisville Downtown
Lounge

Stellar Suites

Stellar Suites
4.5 star property
Downtown Louisville
9.6 out of 10, Exceptional, (130 reviews)
"Easy check in and check out process and very convenient location."
United States
Richard
The price is €161
includes taxes & fees
12 Apr - 13 Apr
Stellar Suites
Property entrance

The Pepin Mansion Historic B&B

The Pepin Mansion Historic B&B
4.0 star property
New Albany
9.8 out of 10, Exceptional, (680 reviews)
"It was wonderful. I would stay again. "
United States
Chassity
The price is €81
includes taxes & fees
12 Apr - 13 Apr
The Pepin Mansion Historic B&B
Seasonal outdoor pool

CozySuites at Nulu

CozySuites at Nulu
4.0 star property
Downtown Louisville
7.8 out of 10, Good, (28 reviews)
"Garage key didn’t work so I had to park on the street until someone would answer the phone. Car was towed and after retrieving the car it still took three hours to get a working garage key "
United States
Carl
The price is €161
includes taxes & fees
12 Apr - 13 Apr
CozySuites at Nulu
Exterior

Bourbon Barrel Inn Bed & Breakfast

Bourbon Barrel Inn Bed & Breakfast
4.0 star property
Old Louisville
10.0 out of 10, Exceptional, (4 reviews)
"Inn Keepers were wonderful. "
United States
jonathan
Bourbon Barrel Inn Bed & Breakfast
32-inch Smart TV with cable channels

The Reserve on Main

The Reserve on Main
4.0 star property
Downtown Louisville
10.0 out of 10, Exceptional, (2 reviews)
"Incredible stay. This stay was clean and inspiring for anyone wishing to take a break and recharge. We highly recommend this stay to everyone staying in the city. "
Canada
georgios
The Reserve on Main
Exterior

stayAPT Suites Louisville North-Clarksville

stayAPT Suites Louisville North-Clarksville
4.0 star property
Clarksville
9.8 out of 10, Exceptional, (46 reviews)
"room very good i love hotel ❤️"
United States
Kartar
stayAPT Suites Louisville North-Clarksville
Family House, Multiple Beds | Private kitchen

Spacious 3 BR Ranch House W Patio Yard in a Quiet Suburb

Spacious 3 BR Ranch House W Patio Yard in a Quiet Suburb
4.0 star property
Sellersburg
9.4 out of 10, Exceptional, (10 reviews)
"Very nice house in a nice neighborhood, spacious home environmental, felt more that at home there,"
United States
Tammy
Spacious 3 BR Ranch House W Patio Yard in a Quiet Suburb
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Learn more about Southern Indiana

Find lots to see and do in Southern Indiana—live music, sports teams and sights from Patoka Lake Swimming Beach to Patoka Lake.

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Top Southern Indiana Hotel Reviews

DoubleTree by Hilton Evansville

DoubleTree by Hilton Evansville

8/10 Good
"Room was nice, we were placed behind the elevator so a bit noisey."
Chase 1-night trip
Posted 5 days ago
DoubleTree by Hilton Evansville

Frequently asked questions

What are the best 4-star hotels in Southern Indiana?
Based on reviews by our guests, Galt House Hotel Trademark Collection by Wyndham is among the best 4-star hotels in Southern Indiana. Situated in Louisville, it includes massage services and beauty services. Hyatt Regency Louisville is another sought-after option here. Also with a 4-star rating and offering premium bedding and designer toiletries, you're sure to have a comfortable stay.
How much does it cost to stay in a 4-star hotel in Southern Indiana?
To book a 4-star hotel in Southern Indiana that's within your budget, take advantage of Expedia's handy filters. Take a look at what's available during your preferred dates and use our pricing filter to set your limit. You can also sort your results by the most budget-friendly option first.

  • Search for the lowest price from €81

What's the difference between 5-star and 4-star hotels in Southern Indiana?
Give yourself the luxury treatment during your Southern Indiana escape by checking in to a 4-star hotel. As well as featuring upmarket surroundings, these properties are typically packed with amenities such as large beds, bathrobes and plenty more. A 5-star hotel will go the extra mile to make your stay an even more indulgent and memorable one. 24-hour concierge assistance, luxurious spas and world-class dining are a few of the exclusive services and conveniences you'll likely be able to enjoy.