Photo by Ryan Watts

4 Star Hotels in Upstate South Carolina, South Carolina

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Check availability on Upstate South Carolina 4 Star Hotels

Tonight
2 Dec - 3 Dec
Tomorrow
3 Dec - 4 Dec
This weekend
5 Dec - 7 Dec
Next weekend
12 Dec - 14 Dec

Top Upstate South Carolina 4 Star Hotels

Lobby
Grand Bohemian Lodge Greenville, Autograph Collection

Grand Bohemian Lodge Greenville, Autograph Collection

4.0 star property
Greenville Downtown
9.6 out of 10, Exceptional, (411)
"The staff were really sweet and responsive. The views from the rooms are breathtaking! "
United States
Krystal
The price is €264
includes taxes & fees
18 Dec - 19 Dec
Grand Bohemian Lodge Greenville, Autograph Collection
Meeting facility
The Westin Poinsett Greenville

The Westin Poinsett Greenville

4.0 star property
Greenville Downtown
9.2 out of 10, Wonderful, (1003)
"Room was much smaller than other Westin's but great location and friendly staff"
United States
Aanal
The price is €128
includes taxes & fees
22 Dec - 23 Dec
The Westin Poinsett Greenville
In-room safe, blackout curtains, soundproofing, iron/ironing board
The Shepherd Hotel Downtown Clemson

The Shepherd Hotel Downtown Clemson

4.0 star property
Clemson
9.8 out of 10, Exceptional, (736)
"Wonderful staff, great location"
United States
Shelly
The price is €162
includes taxes & fees
7 Dec - 8 Dec
The Shepherd Hotel Downtown Clemson
Restaurant
Hotel Hartness

Hotel Hartness

4.0 star property
Greenville
9.8 out of 10, Exceptional, (623)
"Beautiful location, friendly staff"
United States
Andrew
The price is €181
includes taxes & fees
7 Dec - 8 Dec
Hotel Hartness
Premium bedding, down duvets, pillow-top beds, in-room safe
Greenville Marriott

Greenville Marriott

4.0 star property
Greenville
8.6 out of 10, Excellent, (606)
"we enjoyed the bar"
United States
Elizabeth
The price is €88
includes taxes & fees
20 Dec - 21 Dec
Greenville Marriott
Two Bedroom Suite
Mint House Greenville - Downtown

Mint House Greenville - Downtown

4.0 star property
Greenville Downtown
9.2 out of 10, Wonderful, (771)
"Excellent stay as always! "
United States
Elena
The price is €104
includes taxes & fees
24 Dec - 25 Dec
Mint House Greenville - Downtown
Meeting facility
The Abernathy of Clemson

The Abernathy of Clemson

4.0 star property
Clemson
9.6 out of 10, Exceptional, (555)
"location is amazing! "
United States
colleen
The Abernathy of Clemson
Apartment, 2 Bedrooms | Living area
Park Place Apartments by Landing

Park Place Apartments by Landing

4.0 star property
Greenville
7.6 out of 10, Good, (41)
"Great place for a different experience Enjoyed the train "
United States
Edward
Park Place Apartments by Landing
Trailside Wedge Cottage | Terrace/patio
The Station by Compo Hotels

The Station by Compo Hotels

4.0 star property
Travelers Rest
10.0 out of 10, Exceptional, (15)
"great place perfect for more privacy vs. a standard hotel"
United States
John
The price is €276
includes taxes & fees
17 Dec - 18 Dec
The Station by Compo Hotels
Bar (on property)
Hotel Domestique

Hotel Domestique

4.0 star property
Travelers Rest
9.6 out of 10, Exceptional, (30)
"Overall it was an exceptional experience and would highly recommend to anyone looking for a quiet get away."
United States
Chuck
The price is €308
includes taxes & fees
1 Jan - 2 Jan 2026
Hotel Domestique
Restaurant
Liberty Hall Bed and Breakfast

Liberty Hall Bed and Breakfast

4.0 star property
Pendleton
10.0 out of 10, Exceptional, (76)
"The owners are amazing. Comfy rooms, stellar breakfast and good people. "
United States
Renee
The price is €163
includes taxes & fees
20 Dec - 21 Dec
Liberty Hall Bed and Breakfast
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Learn more about Upstate South Carolina

Check out the local area in Upstate South Carolina—home to attractions like Discovery Island Water Park and Heritage Park.

See all hotels in Upstate South Carolina
It is only a 1 mile hike to this beauty. View a video about it here: https://www.hdcarolina.com/episode/riley-moore-falls #Waterfall
Photo by Ryan Watts
Open Photo by Ryan Watts

Top Upstate South Carolina Hotel Reviews

The Westin Poinsett Greenville

The Westin Poinsett Greenville

10/10 Excellent
"Easy check in and rooms were clean. The hotel has an old charm to it and is in a great location. "
Daniel 1-night trip
Posted 9 days ago
The Westin Poinsett Greenville
Grand Bohemian Lodge Greenville, Autograph Collection

Grand Bohemian Lodge Greenville, Autograph Collection

10/10 Excellent
"Loved the location, attention to design details in all spaces, complimentary cocktails and delicious lunch in hotel restaurant. Really used the swamp rabbit trail right outside…"
marcy 2-night trip
Posted 9 days ago
Grand Bohemian Lodge Greenville, Autograph Collection

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