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Upstate South Carolina Hotels
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Our top choices for Upstate South Carolina hotels
Carolina Inn Anderson Clemson Area
Carolina Inn Anderson Clemson AreaAnderson
8.0 out of 10, Very good, (4 reviews)
"Clean room and great staff. Shops were nearby."
Trevor
The price is €53
includes taxes & fees
11 Jun - 12 Jun
Deluxe Inn
Deluxe InnMauldin
9.6 out of 10, Exceptional, (4 reviews)
"Jarod was very helpful and friendly. Amazing location. Within 1/2 mi several restaurants as well as 2 grocery stores. Very safe area as well as friendly folk. So close to Greenville concert hall. Definitely will stay again."
Diane
The price is €60
includes taxes & fees
15 Jun - 16 Jun
Quality Inn Seneca Clemson Area US-123
Quality Inn Seneca Clemson Area US-123Downtown
8.0 out of 10, Very good, (711 reviews)
"Clean room comfortable beds"
Cheryl
The price is €86
includes taxes & fees
14 Jun - 15 Jun
Best Western Plus Clemson Hotel & Conference Center
Best Western Plus Clemson Hotel & Conference CenterClemson
8.2 out of 10, Very good, (1,001 reviews)
"We always stay here when in Clemson. It's convenient and the breakfast and restaurant are great."
Greg
The price is €92
includes taxes & fees
14 Jun - 15 Jun
Lakeside Lodge Clemson
Lakeside Lodge ClemsonSeneca
9.0 out of 10, Wonderful, (1,010 reviews)
"I enjoyed my stay and all the amenities were excellent! I can’t wait to return!"
Renata
The price is €117
includes taxes & fees
9 Jul - 10 Jul
The Inn at Patrick Square
The Inn at Patrick SquareClemson
9.8 out of 10, Exceptional, (859 reviews)
"Terrific place to stay and the staff was very helpful too."
Anne
The price is €143
includes taxes & fees
16 Jun - 17 Jun
Inn @ Clemson
Inn @ ClemsonClemson
8.0 out of 10, Very good, (1,007 reviews)
"Wonderful stay "
Scott
The price is €77
includes taxes & fees
11 Jun - 12 Jun
Holiday Inn Express & Suites Greenville SE - Simpsonville by IHG
Holiday Inn Express & Suites Greenville SE - Simpsonville by IHGSimpsonville
9.4 out of 10, Exceptional, (536 reviews)
"Great place to stay"
Karen
The price is €124
includes taxes & fees
20 Jun - 21 Jun
Hampton Inn Gaffney
Hampton Inn GaffneyGaffney
8.8 out of 10, Excellent, (729 reviews)
"Everything was great!"
Cristen
The price is €79
includes taxes & fees
28 Jun - 29 Jun
La Quinta Inn & Suites by Wyndham Greenville Woodruff Rd.
La Quinta Inn & Suites by Wyndham Greenville Woodruff Rd.Greenville
8.6 out of 10, Excellent, (248 reviews)
"Hotel is near shopping and Restaurants"
Kristina
The price is €76
includes taxes & fees
9 Jul - 10 Jul
Fairfield Inn & Suites Seneca Clemson Univ Area
Fairfield Inn & Suites Seneca Clemson Univ AreaSeneca
9.4 out of 10, Exceptional, (235 reviews)
"Excellent in every way … staff, room, amenities and very comfortable bed!"
Sarah
The price is €114
includes taxes & fees
18 Jun - 19 Jun
Carolina Camp Cedar
Carolina Camp CedarPickens
10.0 out of 10, Exceptional, (3 reviews)
"The cottage was clean, staff was so friendly, our stay was quiet and peaceful… it was perfect! Definitely planning to stay there again!"
Katlynn
The price is €235
includes taxes & fees
16 Jun - 17 Jun
Inn on the Square, an Ascend Collection Hotel
Inn on the Square, an Ascend Collection HotelUptown Greenwood
9.2 out of 10, Wonderful, (744 reviews)
"Great for visiting my granddaughter at Lander. Was attending graduation this time. I always stay here when in town."
Margaret
The price is €106
includes taxes & fees
1 Jul - 2 Jul
Best Western Plus Greenville I-385 Inn & Suites
Best Western Plus Greenville I-385 Inn & SuitesGreenville
9.2 out of 10, Wonderful, (1,505 reviews)
"Location, clean, employees friendly & great breakfast with a reasonable price!"
Charles
The price is €78
includes taxes & fees
14 Jun - 15 Jun
Hampton Inn Greer Greenville, SC
Hampton Inn Greer Greenville, SCGreer
9.6 out of 10, Exceptional, (463 reviews)
"great service all around."
Alberto
The price is €131
includes taxes & fees
13 Jun - 14 Jun
Clemson University's James F. Martin Inn
Clemson University's James F. Martin InnClemson
9.4 out of 10, Exceptional, (1,004 reviews)
"Ery nice and quiet. Comfy beds. Fitness center is small. Would come back and stay here again."
Ryan
The price is €134
includes taxes & fees
11 Jun - 12 Jun
Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG
Holiday Inn Express Hotel & Suites Anderson-I-85 by IHGAnderson
9.2 out of 10, Wonderful, (624 reviews)
"Room was clean and customer service was excellent, check in was smooth "
Gina
The price is €106
includes taxes & fees
14 Jun - 15 Jun
Tru by Hilton Seneca Clemson
Tru by Hilton Seneca ClemsonSeneca
9.2 out of 10, Wonderful, (845 reviews)
"Everything about this hotel was great the staff was very friendly rooms was very clean great location I highly suggest staying here"
Jason
The price is €97
includes taxes & fees
18 Jun - 19 Jun
Hampton Inn & Suites Clinton - I-26
Hampton Inn & Suites Clinton - I-26Clinton
9.0 out of 10, Wonderful, (744 reviews)
"The breakfast was very good and the set up was excellent. "
Sarah
The price is €111
includes taxes & fees
6 Jul - 7 Jul
The Shepherd Hotel Downtown Clemson
The Shepherd Hotel Downtown ClemsonClemson
9.8 out of 10, Exceptional, (813 reviews)
"Great place to stay"
Amy
The price is €146
includes taxes & fees
15 Jun - 16 Jun
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Holiday Rentals in Upstate South Carolina
Cabin
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott BonvoySeneca
9.8 out of 10, Exceptional, (78 reviews)
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Stay near popular Upstate South Carolina attractions
Learn more about Upstate South Carolina
Check out the local area in Upstate South Carolina—home to attractions like Discovery Island Water Park and Heritage Park.
Photo by Ryan Watts
Open Photo by Ryan Watts
Top Upstate South Carolina Hotel Reviews
Hyatt Regency Greenville
10/10 Excellent
More cheap stays in Upstate South Carolina
Sleep Inn Spartanburg Southwest
501 South Blackstock Rd Spartanburg SC
The price is €59 per night from 10 Jul to 11 Jul
€59
10 Jul - 11 Jul
includes taxes & fees
6/10 (614 reviews)
4 Star Hotels
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- 295 Sports Complex
- Visit Anglewood
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- Roper Mountain Science Center
- Runway Park at GMU
- Wade Hampton Mall Shopping Center
- Woodfin Ridge Golf Club
