5 Star Hotels in Santa Cruz, Santa Cruz

    calendar shield illustration

    Change your mind

    Book hotels with free cancellation
    deals illustration

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in
    bed illustration

    Be picky

    Search almost a million properties worldwide

Check availability on Santa Cruz 5 Star Hotels

Top Santa Cruz 5 Star Hotels

Marriott Santa Cruz de la Sierra Hotel
Outdoor pool, pool umbrellas, pool loungers

Marriott Santa Cruz de la Sierra Hotel

5.0 star property
9.0 out of 10, Wonderful, (191)
"Our stay was comfortable and the service was great!"
The price is €103
22 Aug - 23 Aug
Marriott Santa Cruz de la Sierra Hotel
Novotel Santa Cruz De La Sierra
Lobby sitting area

Novotel Santa Cruz De La Sierra

5.0 star property
9.2 out of 10, Wonderful, (95)
"Nice hotel, modern, with pool, good restaurant. Would stay here again without no doubt. "
The price is €90
27 Aug - 28 Aug
Novotel Santa Cruz De La Sierra
Radisson Hotel Santa Cruz
Outdoor pool

Radisson Hotel Santa Cruz

5.0 star property
8.8 out of 10, Excellent, (234)
"Great experience! Great place to stay! "
Radisson Hotel Santa Cruz
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Santa Cruz.
Camino Real Hotel

Camino Real Hotel

Av. San Martín y 4to. Anillo, Equipetrol Norte, Santa Cruz
The price is €121 per night from 1 Sept to 2 Sept
€121
1 Sept - 2 Sept
8.8/10 Excellent! (396 reviews)
Still don't see what you're looking for?
See all properties in Santa Cruz.
You can also use these popular filters to refine your search.
PoolSpaHot tubBreakfast includedWaterpark
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Santa Cruz

Experience Bolivia as the locals see it in the country’s busiest city, where the museums, public squares and churches give you a glimpse into their everyday lives.

See all hotels in Santa Cruz
San Lorenzo Cathedral featuring a garden

Top Santa Cruz Hotel Reviews

Novotel Santa Cruz De La Sierra

Novotel Santa Cruz De La Sierra

10/10 Excellent
"The best place , best workers"
Leo 1-night trip
Posted 4 months ago
Novotel Santa Cruz De La Sierra
Marriott Santa Cruz de la Sierra Hotel

Marriott Santa Cruz de la Sierra Hotel

10/10 Excellent
"Everything was amazing! Great staff and amazing service! "
Laura 2-night trip
Posted 5 months ago
Marriott Santa Cruz de la Sierra Hotel

Frequently asked questions

What are the best 5-star hotels in Santa Cruz?
If you're looking for a 5-star experience, Marriott Santa Cruz de la Sierra Hotel offers one of the best of them according to our customer reviews. Stay at this Santa Cruz getaway and you can look forward to the highest standard of service, upscale furnishings and superior facilities.
How much does it cost to stay in a 5-star hotel in Santa Cruz?
How much you pay for a 5-star hotel in Santa Cruz depends on things like when you plan to go and the length of your holiday. An insider tip for landing the best deal? Use our pricing filters to compare all of the available hotels for your preferred dates.

  • Search for the lowest price per night from €65

What makes a hotel 5 stars in Santa Cruz?
Faultless guest service chatacterises every 5-star hotel in Santa Cruz. From the second you arrive, staff attend to your every whim, whether arranging valet parking or providing a nightly turn-down service. Plus, hotels must feature top-rate conveniences to meet the standard for a 5-star rating. These can include deluxe baths, spa facilities, pools, fine dining kitchens and knowledgeable concierge.