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Our top choices for Santa Cruz hotels

Casa Por Temporadas

Casa Por Temporadas
2.0 star property
Santa Cruz
10.0 out of 10, Exceptional, (1 review)
"The front desk staff was amazing! We checked in during a rain storm and the hotel had been hit by lightning and their computers and they computers were out. The staff maintained their professionalism and got us in a room quickly. Thank you for your help "
United States
Cynthia
Casa Por Temporadas

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
3.5 star property
Santa Cruz
9.0 out of 10, Wonderful, (372 reviews)
"Great"
United States
Maria helena
The price is €112
30 May - 31 May
Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

Marriott Santa Cruz de la Sierra Hotel

Marriott Santa Cruz de la Sierra Hotel
5.0 star property
Santa Cruz
9.0 out of 10, Wonderful, (230 reviews)
"Amazing time"
United States
JORGE
The price is €108
29 May - 30 May
Marriott Santa Cruz de la Sierra Hotel

Sun Hotel

Sun Hotel
3.5 star property
Santa Cruz
8.2 out of 10, Very good, (370 reviews)
"It’s close to the airport and a good spot to rest if you have a long layover. "
United States
Jon
The price is €92
6 May - 7 May
Sun Hotel

Camino Real Hotel

Camino Real Hotel
4.5 star property
Santa Cruz
9.0 out of 10, Wonderful, (426 reviews)
"Good property the great amenities and service"
United States
James
The price is €111
30 May - 31 May
Camino Real Hotel

Premium Suites Deluxe Aparthotel Equipetrol

Premium Suites Deluxe Aparthotel Equipetrol
3.5 star property
Santa Cruz
9.0 out of 10, Wonderful, (95 reviews)
"Great Location"
United States
Blanca
The price is €33
6 May - 7 May
Premium Suites Deluxe Aparthotel Equipetrol

Ibis Santa Cruz DE LA Sierra

Ibis Santa Cruz DE LA Sierra
3.0 star property
Santa Cruz
9.6 out of 10, Exceptional, (109 reviews)
"Nice place"
United States
Juan Carlos
The price is €47
4 May - 5 May
Ibis Santa Cruz DE LA Sierra

Novotel Santa Cruz De La Sierra

Novotel Santa Cruz De La Sierra
5.0 star property
Santa Cruz
9.2 out of 10, Wonderful, (111 reviews)
"REALLY NICE HOTEL. STAFF WONDERFULL"
United States
ERNESTO
The price is €90
24 May - 25 May
Novotel Santa Cruz De La Sierra

Chairú Eco Hotel

Chairú Eco Hotel
3.5 star property
Santa Cruz
9.4 out of 10, Exceptional, (63 reviews)
"Clean and close to the malls and restaurants "
United States
Luis
The price is €48
5 May - 6 May
Chairú Eco Hotel

Hampton by Hilton Santa Cruz/Equipetrol, Bolivia

Hampton by Hilton Santa Cruz/Equipetrol, Bolivia
4.5 star property
Santa Cruz
9.2 out of 10, Wonderful, (268 reviews)
"Convenient location clean rooms good breakfast with a view "
Canada
Jesus Enrique Cabello
The price is €80
14 May - 15 May
Hampton by Hilton Santa Cruz/Equipetrol, Bolivia

Apart Hotel Premium Suites Santa Cruz

Apart Hotel Premium Suites Santa Cruz
3.5 star property
Santa Cruz
8.6 out of 10, Excellent, (101 reviews)
"Place is clean , safe area , walking distance to shops "
United States
Nataly
The price is €23
6 May - 7 May
Apart Hotel Premium Suites Santa Cruz

Hotel Cortez

Hotel Cortez
3.5 star property
Santa Cruz
9.2 out of 10, Wonderful, (137 reviews)
"Lovely hotel. Great room, location, staff and amenities. "
Norway
Solvei Emily Brekke
The price is €91
8 May - 9 May
Hotel Cortez

Prince Hotel

Prince Hotel
3.0 star property
Santa Cruz
9.4 out of 10, Exceptional, (3 reviews)
"Nice place "
United States
Marco
The price is €48
4 May - 5 May
Prince Hotel

HOTEL OSHO

HOTEL OSHO
3.5 star property
Santa Cruz
9.4 out of 10, Exceptional, (49 reviews)
"Room was great and staff were very accommodating!"
Canada
David
The price is €49
15 May - 16 May
HOTEL OSHO

Delfines Collection Hotel By Mercure

Delfines Collection Hotel By Mercure
3.5 star property
Santa Cruz
9.0 out of 10, Wonderful, (88 reviews)
"Rooms are always spotless good breakfasts rooftop pool with decent view "
Canada
Peter
The price is €41
19 May - 20 May
Delfines Collection Hotel By Mercure

Alfonsina Hotel Boutique by Inboccaluppo

Alfonsina Hotel Boutique by Inboccaluppo
3.5 star property
Santa Cruz
9.4 out of 10, Exceptional, (43 reviews)
"Beautiful place, wonderful artwork"
United States
Elizabeth
The price is €69
21 May - 22 May
Alfonsina Hotel Boutique by Inboccaluppo

Hotel Las Américas

Hotel Las Américas
3.0 star property
Santa Cruz
7.6 out of 10, Good, (7 reviews)
"Very clean room and great staff"
Canada
Stanley
The price is €30
4 May - 5 May
Hotel Las Américas

TRYP by Wyndham Santa Cruz

TRYP by Wyndham Santa Cruz
4.0 star property
Santa Cruz
9.2 out of 10, Wonderful, (160 reviews)
"My go too hotel whenever I'm in town! "
United States
Pluetina
The price is €84
4 May - 5 May
TRYP by Wyndham Santa Cruz

Hotel LP Equipetrol

Hotel LP Equipetrol
3.5 star property
Santa Cruz
8.2 out of 10, Very good, (205 reviews)
"Nice place to stay"
United States
Ricardo
The price is €32
9 May - 10 May
Hotel LP Equipetrol

Swissôtel Santa Cruz De La Sierra

Swissôtel Santa Cruz De La Sierra
4.5 star property
Santa Cruz
9.2 out of 10, Wonderful, (87 reviews)
"Beautiful hotel"
Australia
Joanna
The price is €107
18 May - 19 May
Swissôtel Santa Cruz De La Sierra
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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Top Santa Cruz Hotel Reviews

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Frequently asked questions

How much do hotels in Santa Cruz cost?
The season and factors like school holidays, Christmas and Easter can influence the price of a hotel in Santa Cruz. You can find cheap options from €23 in a few different ways on Expedia. First, key in the dates you'd like to go on holiday, then use the filters such as property type and amenities to refine your search. You can also sort by price, so the most inexpensive options appear at the top.
When is the best time to go to Santa Cruz?
If you're thinking of visiting in summer, reserve your Santa Cruz hotel between December and February. Temperatures during the summer here range from 22ºC to 31ºC. Santa Cruz has an oceanic climate, so pack appropriately.
Are there any luxury hotels in Santa Cruz?
Expedia has got some terrific stays for an indulgent escape in Santa Cruz, Santa Cruz, such as Hampton by Hilton Santa Cruz/Equipetrol, Bolivia. Check in and make use of amenities like concierge services, a garden and complimentary breakfast. Alternatively, treat yourself at Radisson Hotel Santa Cruz.
What are the top all-inclusive hotels in Santa Cruz?
If you're looking for a relaxed and worry-free escape, throw your bags down at Prince Hotel. Generally including your drinks, food and some recreational activities in the flat upfront rate, it's one of the best options for an all-inclusive retreat in Santa Cruz.
How can I find cheap hotels in Santa Cruz?
Discover inexpensive hotels with minimal effort by making use of our filter tool. Choose the "Price per night" box to view low-cost options in Santa Cruz. Another way is to take a look at our cheap hotels in Santa Cruz page. The lowest price available starts from €23 per night.
What are the best hotels in Santa Cruz for families?
Cosmopolitano Hotel Boutique is one of the top-rated hotels for families, located in Santa Cruz, Santa Cruz. Book here and take advantage of conveniences such as complimentary breakfast and a cafe. Hampton by Hilton Santa Cruz/Equipetrol, Bolivia is another favourite where kiddos are welcome. For more hotel options, fine-tune your search results by selecting "Family friendly" under the "Traveller experience" filter heading.
Why should I book my Santa Cruz hotel with Expedia?
Book your Santa Cruz hotel with Expedia and enjoy a world of options at unbeatable prices. Use our search filters to help you find exactly what you want, whether that's a 5-star escape or something a little more unique, like a houseboat, log cabin or villa! Join Expedia Rewards and you'll save 10% or more on over 100,000 hotels worldwide when you're signed in. Collect points on eligible bookings, which you can use to save on your next epic adventure. Plus, many of our hotels come with flexible cancellation policies, so you can rest easy if your plans happen to change.