5 Star Hotels in Syracuse, Sicily
Change your mind
Book hotels with free cancellation
Be picky
Search almost a million properties worldwide
Check availability on Syracuse 5 Star Hotels
Top Syracuse 5 Star Hotels

Grand Hotel Ortigia Siracusa
Grand Hotel Ortigia Siracusa
9.0 out of 10, Wonderful, (553)
The price is €330
includes taxes & fees
1 Sept - 2 Sept

Ortea Palace Hotel, Sicily, Autograph Collection
Ortea Palace Hotel, Sicily, Autograph Collection
9.4 out of 10, Exceptional, (238)
The price is €369
includes taxes & fees
29 Aug - 30 Aug

Caportigia Boutique Hotel
Caportigia Boutique Hotel
9.4 out of 10, Exceptional, (240)
The price is €205
includes taxes & fees
30 Aug - 31 Aug

Grand Hotel Des Ètrangers - The Leading Hotels of the World
Grand Hotel Des Ètrangers - The Leading Hotels of the World
9.4 out of 10, Exceptional, (61)
The price is €650
includes taxes & fees
1 Sept - 2 Sept

Dimora Caiammari Luxury Hotel & Spa
Dimora Caiammari Luxury Hotel & Spa
9.2 out of 10, Wonderful, (203)

Minareto
Minareto
8.8 out of 10, Excellent, (262)

Wellness & Spa Hotel Principe di Fitalia
Wellness & Spa Hotel Principe di Fitalia
9.6 out of 10, Exceptional, (88)
The price is €316
includes taxes & fees
10 Sept - 11 Sept
Save an average of 15% on thousands of hotels when you're signed in
Explore similar 4-star hotels
Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Syracuse.

Algila' Ortigia Charme Hotel
Via Vittorio Veneto 93, Syracuse, SR
Still don't see what you're looking for?
See all properties in Syracuse.
You can also use these popular filters to refine your search.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Learn more about Syracuse
Ancient Greek ruins in the Archaeological Park include the impressive Teatro Greco where summer performances still take place. Wander through Ortygia's narrow streets to discover the Duomo, built around a former Greek temple with columns still visible from inside.

Top Syracuse Hotel Reviews
Explore a world of travel with Expedia
Explore a world of travel with Expedia
Areas of Syracuse
Hotel Theme
- Adventure Sport Hotels in Syracuse
- Beach Hotels in Syracuse
- Boutique Hotels in Syracuse
- Casino Hotels in Syracuse
- Cheap Hotels in Syracuse
- Family Friendly Hotels in Syracuse
- Golf Hotels in Syracuse
- Historic Hotels in Syracuse
- Hotels with Air Conditioning in Syracuse
- Hotels with Bar in Syracuse
- Hotels with Breakfast in Syracuse
- Hotels with Childcare in Syracuse
- Hotels with Parking in Syracuse
- Hotels with Pool in Syracuse
- Hotels with Restaurant in Syracuse
- Hotels with Spa in Syracuse
- Hotels with WiFi in Syracuse
- Luxury Hotels in Syracuse
- Pet Friendly Hotels in Syracuse
- Romantic Hotels in Syracuse
- Wedding Hotels in Syracuse
More accommodation types in Syracuse
More top Syracuse Hotels
- Life Hotels Kalaonda Resort
- Hotel Como
- Charme Hotel Henry's House
- Grand Hotel Des Ètrangers - The Leading Hotels of the World
- Maniace Boutique Hotel Ortigia UNA Esperienze
- Mercure Siracusa Prometeo
- Eureka Palace Hotel Spa Resort
- Lanterne Magiche Ortigia
- Palazzo Artemide - VRetreats
- Caportigia Boutique Hotel
- Hotel Posta
- Park Hotel
- Dimora Caiammari Luxury Hotel & Spa
- Nostos rooms & Apartments
- VOI Arenella Resort
- Dolce by Wyndham Siracusa I Monasteri Golf & Spa
- Hotel Gargallo
- Palazzo Gilistro
- Hotel Palazzo Cavalieri
- Minareto
Expedia's Latest Trends
Hotels
Activities
Holiday Rentals