A coastal fortress with a stone wall and a tiled-roof building.

5 Star Hotels in Syracuse, Sicily

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Check availability on Syracuse 5 Star Hotels

Tonight
31 Aug - 1 Sept
Tomorrow
1 Sept - 2 Sept
This weekend
4 Sept - 6 Sept
Next weekend
11 Sept - 13 Sept

Our top choices for Syracuse 5-star hotels

1. Ortea Palace Hotel, Sicily, Autograph Collection

Ortea Palace Hotel, Sicily, Autograph Collection
Ortigia
United States
kira
€490
includes taxes & fees
1 Sept - 2 Sept
Ortea Palace Hotel, Sicily, Autograph Collection

2. Grand Hotel Ortigia Siracusa

Grand Hotel Ortigia Siracusa
Ortigia
United States
NINA
€352
includes taxes & fees
1 Sept - 2 Sept
Grand Hotel Ortigia Siracusa

3. Grand Hotel Des Ètrangers - The Leading Hotels of the World

Grand Hotel Des Ètrangers - The Leading Hotels of the World
Ortigia
Australia
Leanne
€691
includes taxes & fees
3 Sept - 4 Sept
Grand Hotel Des Ètrangers - The Leading Hotels of the World

4. Caportigia Boutique Hotel

Caportigia Boutique Hotel
Santa Lucia
Canada
Alessia
€210
includes taxes & fees
2 Sept - 3 Sept
Caportigia Boutique Hotel

5. Minareto

Minareto
Syracuse
United States
Nariman
€412
includes taxes & fees
1 Sept - 2 Sept
Minareto

6. Wellness & Spa Hotel Principe di Fitalia

Wellness & Spa Hotel Principe di Fitalia
Syracuse
United States
Jeffrey
€395
includes taxes & fees
1 Sept - 2 Sept
Wellness & Spa Hotel Principe di Fitalia

7. Dimora Caiammari Luxury Hotel & Spa

Dimora Caiammari Luxury Hotel & Spa
Syracuse
United States
Jing
€326
includes taxes & fees
6 Sept - 7 Sept
Dimora Caiammari Luxury Hotel & Spa
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Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Syracuse.
Algila' Ortigia Charme Hotel

Algila' Ortigia Charme Hotel

Via Vittorio Veneto 93 Syracuse SR
€293
3 Sept - 4 Sept
includes taxes & fees
9.6/10 Exceptional! (1,004 reviews)
Algila' Ortigia Charme Hotel
Dolce by Wyndham Siracusa I Monasteri Golf & Spa

Dolce by Wyndham Siracusa I Monasteri Golf & Spa

Traversa Monasteri Di Sotto, 3 Syracuse SR
€85
6 Sept - 7 Sept
includes taxes & fees
7.4/10 Good! (44 reviews)
Dolce by Wyndham Siracusa I Monasteri Golf & Spa
UNA Hotels One Siracusa Wellness & SPA

UNA Hotels One Siracusa Wellness & SPA

Via Diodoro Siculo 4 Syracuse SR
€159
17 Sept - 18 Sept
includes taxes & fees
8.6/10 Excellent! (550 reviews)
UNA Hotels One Siracusa Wellness & SPA
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Syracuse

Ancient Greek ruins in the Archaeological Park include the impressive Teatro Greco where summer performances still take place. Wander through Ortygia's narrow streets to discover the Duomo, built around a former Greek temple with columns still visible from inside.

See all hotels in Syracuse
An ancient amphitheater with stone ruins and a grassy field.

Top Syracuse Hotel Reviews

Ortea Palace Hotel, Sicily, Autograph Collection

Ortea Palace Hotel, Sicily, Autograph Collection

10/10 Excellent
"We had a fantastic stay at Ortea Palace. I was travelling with my 2 kids - 11 and 15. The hotel is very conveniently located in Ortigia - right across the bridge from Syracusa so easy access to both. The main train station is about 15 mins walk from the hotel. A lot of good restaurants nearby and the main promenade within 10mins walk away. The room was a duplex with two double beds and two bathrooms, which worked great for the three of us. The hotel staff was amazing - anyone from the reception to the staff at the breakfast was super helpful and nothing was too much for them. We were told that this was one of the few luxury hotels in Syracusa. It was clean, modern, conveniently located with super helpful staff and good value for money."
Katya 6-night trip
Posted 20 hours ago
Ortea Palace Hotel, Sicily, Autograph Collection
Grand Hotel Ortigia Siracusa

Grand Hotel Ortigia Siracusa

10/10 Excellent
"Old world Italian charm and great service. Would have preferred something more centrally located with a pool and better breakfast."
Karen 3-night trip
Posted 2 days ago
Grand Hotel Ortigia Siracusa

Frequently asked questions

What are the best 5-star hotels in Syracuse?
Grand Hotel Ortigia Siracusa, Ortea Palace Hotel, Sicily, Autograph Collection and Grand Hotel Des Ètrangers are some of the top 5-star hotels in Syracuse, according to our customer reviews. These plush hotels rate highly for things such as their amenities, location and guest services. Book your favourite and enjoy all the luxury perks.
How much does it cost to stay in a 5-star hotel in Syracuse?
There are a variety of pricing options for a 5-star hotel in Syracuse on Expedia. The amount you pay will depend on when you want to travel, length of your trip and other factors. Compare all of the available accommodation for your desired dates and make use of our pricing and other filters to find the ideal upscale stay.
  • Search for the lowest price per night from €85
What makes a hotel 5 stars in Syracuse?
Impeccable guest service chatacterises every 5-star hotel in Syracuse. From the moment you enter the lobby, staff ensure your every need is met, whether arranging customised tours or providing in-room beauty treatments. On top of that, hotels must feature superior amenities to be entitled to a 5-star rating. These can include luxury bathrooms, on-site spa facilities, swimming pools, gourmet kitchens and knowledgeable concierge.

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