A coastal fortress with a stone wall and a tiled-roof building.

5 Star Hotels in Syracuse, Sicily

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Check availability on Syracuse 5 Star Hotels

Tonight
15 Oct - 16 Oct
Tomorrow
16 Oct - 17 Oct
This weekend
16 Oct - 18 Oct
Next weekend
23 Oct - 25 Oct

Our top choices for Syracuse 5-star hotels

A large, historic building with multiple floors, a prominent tower, and a waterfront marina with boats.
A grand atrium with a central column, ornate railings, and a large mural on the wall.
A balcony with a glass table and two red chairs, overlooking a coastal view with buildings and boats.
A balcony with a view of the sea and a cityscape, furnished with two chairs and a small table with a vase of flowers.

1. Ortea Palace Hotel, Sicily, Autograph Collection

Ortea Palace Hotel, Sicily, Autograph Collection
Ortigia
Mexico
ALFONSO
€297
includes taxes & fees
8 Nov - 9 Nov
Ortea Palace Hotel, Sicily, Autograph Collection
A balcony with a view of the sea, a cactus, and potted plants.
A large, multi-story building with a symmetrical facade, arched windows, and a central entrance with a colorful awning.
A poolside area with lounge chairs and umbrellas, a clear pool, and a building with multiple windows in the background.
A large, classical building with multiple windows and balconies, surrounded by a calm body of water with several yachts docked.

2. Grand Hotel Ortigia Siracusa

Grand Hotel Ortigia Siracusa
Ortigia
United States
SEAN
€334
includes taxes & fees
1 Nov - 2 Nov
Grand Hotel Ortigia Siracusa
A poolside area with lounge chairs and umbrellas, a clear blue pool, and a building with balconies.
A grand hallway with ornate columns, a tiled floor, and large potted plants.
A terrace with a view of the sea and a cruise ship, featuring outdoor seating and potted cacti.
A spacious dining area with round tables and blue chairs, large windows offering a city view, and a wooden ceiling structure.

3. Grand Hotel Des Ètrangers - The Leading Hotels of the World

Grand Hotel Des Ètrangers - The Leading Hotels of the World
Ortigia
Canada
Steven
€691
includes taxes & fees
20 Oct - 21 Oct
Grand Hotel Des Ètrangers - The Leading Hotels of the World
A rooftop terrace with lounge chairs, a hot tub, and a view of palm trees and buildings.
A multi-story building with a rooftop terrace, balconies, and a street view.
A modern hotel room with a stone accent wall, a grey sofa, a large mirror, a chandelier, and a neatly made bed with rolled towels.
A multi-story building with a rooftop terrace featuring outdoor seating and a hot tub.

4. Caportigia Boutique Hotel

Caportigia Boutique Hotel
Santa Lucia
Canada
Dena
€160
includes taxes & fees
5 Nov - 6 Nov
Caportigia Boutique Hotel
A spa room with a large window, a hot tub, and two candles.
A spacious lobby with arched ceilings, a central round table with decorative items, and a modern chandelier.
A courtyard with a stone pathway, palm trees, and potted plants.
A stone building with arched walkways and outdoor seating areas.

5. Dimora Caiammari Luxury Hotel & Spa

Dimora Caiammari Luxury Hotel & Spa
Syracuse
United Kingdom
Chris
€317
includes taxes & fees
16 Oct - 17 Oct
Dimora Caiammari Luxury Hotel & Spa
An aerial view of a resort with multiple swimming pools, palm trees, and a clear view of the coastline.
A modern bathroom with a freestanding bathtub, a small table with toiletries, and a view of the ocean.
A modern bathroom with a freestanding bathtub, a round table with a magazine, and a view of a pool and greenery.
A pathway lined with palm trees leading to a building with a red-tiled roof.

6. Minareto

Minareto
Syracuse
United States
Luis Alberto
€317
includes taxes & fees
6 Nov - 7 Nov
Minareto
A large swimming pool with a modern building in the background.
An outdoor dining area with tables and chairs, a pool, and palm trees in the background.
A beach with clear turquoise water, sandy shore, and sparse vegetation.
A woman relaxing in a spa bath with a modern design, including a ceiling with blue lighting and a tiled floor.

7. Wellness & Spa Hotel Principe di Fitalia

Wellness & Spa Hotel Principe di Fitalia
Syracuse
Australia
Nicholas
€333
includes taxes & fees
5 Nov - 6 Nov
Wellness & Spa Hotel Principe di Fitalia
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Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Syracuse.
Algila' Ortigia Charme Hotel

Algila' Ortigia Charme Hotel

Via Vittorio Veneto 93 Syracuse SR
€199
12 Nov - 13 Nov
includes taxes & fees
9.6/10 Exceptional! (1,002 reviews)
Algila' Ortigia Charme Hotel
UNA Hotels One Siracusa Wellness & SPA

UNA Hotels One Siracusa Wellness & SPA

Via Diodoro Siculo 4 Syracuse SR
€159
25 Oct - 26 Oct
includes taxes & fees
8.6/10 Excellent! (555 reviews)
UNA Hotels One Siracusa Wellness & SPA
Palazzo Artemide - VRetreats, SLH Collection

Palazzo Artemide - VRetreats, SLH Collection

Via Roma 66 Syracuse SR
€221
5 Nov - 6 Nov
includes taxes & fees
9.4/10 Exceptional! (694 reviews)
Palazzo Artemide - VRetreats, SLH Collection
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Learn more about Syracuse

Ancient Greek ruins in the Archaeological Park include the impressive Teatro Greco where summer performances still take place. Wander through Ortygia's narrow streets to discover the Duomo, built around a former Greek temple with columns still visible from inside.

See all hotels in Syracuse
An ancient amphitheater with stone ruins and a grassy field.

Top Syracuse Hotel Reviews

Grand Hotel Des Ètrangers - The Leading Hotels of the World

Grand Hotel Des Ètrangers - The Leading Hotels of the World

10/10 Excellent
"Absolutely beautiful hotel and in a perfect location with beautiful sea view. Wonderful and attentive staff."
nadia 3-night trip
Posted 9 hours ago
Grand Hotel Des Ètrangers - The Leading Hotels of the World
Grand Hotel Ortigia Siracusa

Grand Hotel Ortigia Siracusa

10/10 Excellent
"A splendid, classic property with first rate service, comfortable beds and a glorious breakfast on a breathtaking outdoor terrace. Wish we could have stayed longer."
Richard 1-night trip
Posted 3 days ago
Grand Hotel Ortigia Siracusa

Frequently asked questions

What are the best 5-star hotels in Syracuse?
Grand Hotel Ortigia Siracusa, Ortea Palace Hotel, Sicily, Autograph Collection and Grand Hotel Des Ètrangers are some of the top 5-star hotels in Syracuse, according to our customer reviews. These plush hotels rate highly for things such as their amenities, location and guest services. Book your favourite and enjoy all the luxury perks.
How much does it cost to stay in a 5-star hotel in Syracuse?
There are a variety of pricing options for a 5-star hotel in Syracuse on Expedia. The amount you pay will depend on when you want to travel, length of your trip and other factors. Compare all of the available accommodation for your desired dates and make use of our pricing and other filters to find the ideal upscale stay.
  • Search for the lowest price per night from €159
What makes a hotel 5 stars in Syracuse?
Impeccable guest service chatacterises every 5-star hotel in Syracuse. From the moment you enter the lobby, staff ensure your every need is met, whether arranging customised tours or providing in-room beauty treatments. On top of that, hotels must feature superior amenities to be entitled to a 5-star rating. These can include luxury bathrooms, on-site spa facilities, swimming pools, gourmet kitchens and knowledgeable concierge.

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