All hotels in Upstate South Carolina, South Carolina
Change your mindBook hotels with free cancellation
Be pickySearch almost a million properties worldwide
All hotels in Upstate South Carolina, South Carolina
We have found 3119 Upstate South Carolina Hotels
- Grand Bohemian Lodge Greenville, Autograph Collection
- Days Inn by Wyndham Anderson
- Best Western Plus Clemson Hotel & Conference Center
- Hyatt Place Greenville Downtown
- Best Western Plus Greenville I-385 Inn & Suites
- Hyatt Regency Greenville
- Hotel Hartness
- Embassy Suites Greenville Golf Resort & Conference Center
- Hilton Greenville
- Hyatt Place Greenville/Haywood
- La Quinta Inn & Suites by Wyndham Greenville Woodruff Rd.
- Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG
- The Shepherd Hotel Downtown Clemson
- Aloft by Marriott Greenville Downtown
- Comfort Inn Greenville - Haywood Mall
- Drury Inn & Suites Greenville
- Lakeside Lodge Clemson
- The Westin Poinsett Greenville
- Embassy Suites by Hilton Greenville Downtown Riverplace
- La Quinta by Wyndham Haywood Mall-Near Greenville Downtown
- SpringHill Suites by Marriott Greenville Downtown
- Courtyard by Marriott Greenville Haywood Mall
- Studio 6 Suites Greenville, SC - Haywood Mall
- Comfort Suites At WestGate Mall
- Days Inn by Wyndham Greenville
- Best Western Spartanburg Northwest
- Hampton Inn & Suites Greenville-Downtown-RiverPlace
- Woodspring Suites Greenville Airport
- Quality Inn & Suites Greenville - Haywood Mall
- Courtyard Marriott Clemson
- Holiday Inn Express Hotel & Suites Spartanburg-North by IHG
- Holiday Inn Express & Suites Greenville - Downtown by IHG
- Quality Inn Seneca Clemson Area US-123
- Homewood Suites by Hilton Greenville Downtown
- Microtel Inn & Suites by Wyndham Greenville / Woodruff Rd
- Inn @ Clemson
- AC Hotel By Marriott Greenville
- Greenville Inn and Suites
- MainStay Suites Greenville Airport
- Baymont by Wyndham Greenville Woodruff Rd
- Studio 6 Greenville, SC
- Comfort Suites Greenville Airport
- Clemson University's James F. Martin Inn
- Comfort Inn & Suites Clemson - University Area
- Fairfield Inn & Suites by Marriott Greenville Simpsonville
- Hampton Inn & Suites Greenville Airport, SC
- Spartanburg Marriott
- Fairfield Inn & Suites Seneca Clemson Univ Area
- AC Hotel by Marriott Spartanburg
- Courtyard by Marriott Greenville Downtown
- Urban Boutique Hotel, BW Signature Collection
- Four Points by Sheraton Spartanburg
- Days Inn by Wyndham Spartanburg Waccamaw
- Motel 6 Spartanburg, Sc – Northwest / Business 85
- Courtyard by Marriott Greenville Mauldin
- Wingate by Wyndham - Greenville-Airport
- Tru by Hilton Spartanburg
- Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG
- Hampton Inn Gaffney
- Motel 6 Greenville, SC
- Holiday Inn Greenville - Woodruff Road by IHG
- WoodSpring Suites Spartanburg - Duncan
- Greenville Marriott
- Quality Inn Simpsonville - Greenville
- Best Western Plus Spartanburg
- The Abernathy of Clemson
- Woodspring Suites Anderson North I-85
- Baymont by Wyndham Easley/Greenville
- Extended Stay America Premier Suites Greenville Woodruff Rd
- WoodSpring Suites Greenville Haywood Mall
- Quality Inn & Suites Easley - Greenville
- Home2 Suites by Hilton Greenville Downtown
- Days Inn by Wyndham Clinton / Laurens I-26
- Microtel Inn by Wyndham Duncan/Spartanburg
- Quality Inn Clemson near University
- Hampton Inn Greenville I-385 - Woodruff Rd.
- The Inn at Patrick Square
- Studio 6 Greenville, SC - I-85 Near Downtown
- Courtyard Greenville-Spartanburg by Marriott
- Fairfield Inn by Marriott Greenville-Spartanburg Airport
- Tru by Hilton Seneca Clemson
- Days Inn by Wyndham Easley/Greenville/Clemson Area
- Holiday Inn Express & Suites Greenville-Spartanburg (Duncan) by IHG
- Budget Inn Greenville By Hotel O I-85
- Baymont by Wyndham Greenwood
- Comfort Inn & Suites Greer - Greenville
- Holiday Inn Express & Suites Greenville Airport by IHG
- Hampton Inn Greer Greenville, SC
- Hampton Inn & Suites Seneca-Clemson Area
- ECHO Suites Extended Stay by Wyndham Spartanburg
- Holiday Inn Express & Suites Greenville - Taylors by IHG
- Hilton Garden Inn Anderson
- Comfort Suites Piedmont - Greenville South
- Hampton Inn & Suites Spartanburg-I-26-Westgate Mall
- Holiday Inn Express & Suites Greenwood Mall by IHG
Let Expedia take you to the best Hotels in Upstate South Carolina. You'll find the largest selection of hotel deals, discount prices, and cheap hotel rates on reservations anywhere in the world. Expedia, the leader in world travel, gives you customer reviews, maps, and the best selection of hotels near landmarks and attractions.